- Must visit
California Academy of Sciences
Renowned science museum with rainforest dome, aquarium, and planetarium. Interactive exhibits make it a standout for all ages.
Cheapest price
$20
Average price
$20
Fastest journey
1 h 45 m
Average duration
1 h 45 m
Buses per day
1
Distance
75 km
The best way to find a cheap bus ticket from Vacaville, CA to San Francisco, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Vacaville, CA to San Francisco, CA will cost around $20 if you buy it on the day, but the cheapest tickets can be found for only $20.
Of the 1 buses that leave Vacaville, CA for San Francisco, CA on Sun, Aug 23, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sun, Aug 23 the direct buses cover the 75 km distance in an average of 1 h 45 m but if you time it right, some buses will get you there in just 1 h 45 m .
On Sun, Aug 23 the slowest buses will take 1 h 45 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 04:25AM | Arrival Time 06:05AM | Duration 1h40 | Departure days Tue, Wed, Thu, Fri, Sat, Sun | Cheapest price $16 |
Operator Greyhound | Departure Time 05:25AM | Arrival Time 07:05AM | Duration 1h40 | Departure days Fri, Sat, Sun | Cheapest price $14 |
Operator Greyhound | Departure Time 10:50AM | Arrival Time 12:35PM | Duration 1h45 | Departure days Sun | Cheapest price $20 |
Operator Greyhound | Departure Time 05:40PM | Arrival Time 07:25PM | Duration 1h45 | Departure days Sat | Cheapest price $22 |
The table below shows live departures for Vacaville, CA to San Francisco, CA buses for today, Saturday, August 22. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 5:40 PM Vacaville, CA | 1h45 | 7:25 PM San Francisco, CA | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Take a bus from Vacaville, CA to San Francisco, CA and enjoy the approximately 46 miles (75 km) long journey. Find schedules and pricing options for a convenient and affordable trip.
There are 2 buses per day. The earliest bus runs at 04:56, the last at 21:39.
Distance 46 miles (75 km) |
Average bus duration 1h 45m |
Buses per day 12 |
Direct buses 2 |
First bus 4:56 AM |
Last bus 9:39 PM |
Cheapest Month Mar |
Cheapest Day Sat |
High Season Apr - Jun |
Low Season Oct - Dec |
Busiest Day Mon |
Least Busy Day Mon |
Discover the best of San Francisco, CA — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect San Francisco, CA trip today.
Renowned science museum with rainforest dome, aquarium, and planetarium. Interactive exhibits make it a standout for all ages.
Major fine arts museum in Golden Gate Park with American art, textiles, and a panoramic tower. A classic cultural highlight.
Leading modern and contemporary art museum with landmark architecture and strong global collections. Essential for art-focused visitors.
Large urban park with gardens, lakes, museums, and trails. It is a must for relaxing, walking, and seeing several major attractions.
Steeply curving block lined with flowers and grand homes. This famous street offers classic photos and a quintessential San Francisco scene.
Popular waterfront promenade with bay views, piers, and ferries. Great for walking, people-watching, and connecting to nearby sights.
A crusty loaf with a tangy flavor shaped by the city’s historic wild yeast culture. It is one of San Francisco’s most iconic foods.
Fresh local Dungeness crab, often cracked and served simply or in cioppino. It is a Bay Area seasonal specialty tied to the fishing waterfront.
A tomato-based seafood stew created by Italian American fishermen in North Beach. It is a classic San Francisco dish built from the day’s catch.
Celebrated fine dining destination known for inventive tasting menus and polished service in an elegant, intimate setting.
Historic North Beach seafood house famous for cioppino, crab, and old-school San Francisco waterfront charm.
Legendary Mission taqueria known for large Mission-style burritos and a lively, no-frills local atmosphere.
Very high hotel, dining, and transport costs make San Francisco pricier than most US cities and many major tourist destinations.
Tip 18-20% at restaurants, 15-20% for taxis, and round up or tip $1 at cafes for good service.
Find answers to the most common questions about traveling from Vacaville, CA to San Francisco, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at San Francisco, CA, this guide helps you travel smarter and with confidence.

Most Vacaville, CA to San Francisco, CA buses use the Suisun City, Train Depot to San Francisco, Transit Center Bay 29 station pair. Use this guide to compare Vacaville, CA and San Francisco, CA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
San Francisco, Transit Center Bay 29 is 2 km from San Francisco city centre. Public transport options include:
San Francisco, Transit Center Bay 29 has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at San Francisco, Transit Center Bay 29. ATMs are available at San Francisco, Transit Center Bay 29.
Ticket office support is available at San Francisco, Transit Center Bay 29.
Available at San Francisco, Transit Center Bay 29: Parking, Taxis, WC.
Accessibility facilities are available at San Francisco, Transit Center Bay 29: Wheelchair accessible areas present.
Here are some other resources that might have the information you need