- Must visit
Santa Maria della Scala
A vast former hospital complex opposite the cathedral, now a major museum with archaeological finds, frescoed halls, and temporary exhibitions.
Cheapest price
$84
Average price
$84
Fastest journey
1 d 3 h 35 m
Average duration
1 d 3 h 35 m
Buses per day
1
Distance
592 km
The best way to find a cheap bus ticket from Grottaglie to Siena is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Grottaglie to Siena will cost around $84 if you buy it on the day, but the cheapest tickets can be found for only $84.
It's difficult to get from Grottaglie to Siena without transferring at least once.


Omio recommends booking the bus as it is the most popular option from Grottaglie to Siena among Omio's users. If you are prioritising price take the flight with prices starting from $23. For those with little time consider booking a flight which can get you there in 1h 30m. The ticket price range depends on the travel mode: a flight costs an average of $23, and a bus costs an average of $50.
Distance: 367 miles (592 km)
Most popular Bus | Flight | Driving |
|---|---|---|
$65 Average price | $23 Average price Cheapest | $148 Average price (fuel + tolls) |
11h 31m Average total duration 11h 1m Onboard + 30m Additional time* | 4h 30m Average total duration Fastest 1h 30m Onboard + 3h 0m Additional time* | 7h 30m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Grottaglie to Siena:
A flight is $42 (€34) less than a bus for this route with tickets for a bus from Grottaglie to Siena costing on average $65 (€54).
Other travel options to Siena take longer:
Bus takes on average 11h 1m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Marino Autolinee | Departure Time 04:45AM | Arrival Time 02:50PM | Duration 10h05 | Departure days Mon, Tue, Thu | Cheapest price $68 |
Operator Marino Autolinee | Departure Time 05:45AM | Arrival Time 03:50PM | Duration 10h05 | Departure days Thu, Fri | Cheapest price $50 |
Operator FlixBus | Departure Time 11:15AM | Arrival Time 02:50PM | Duration 27h35 | Departure days Wed, Sat, Sun | Cheapest price $84 |
The table below shows live departures for Grottaglie to Siena buses for today, Friday, July 10. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 5:45 AM Grottaglie | 10h05 | 3:50 PM Siena | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Grottaglie to Siena run on average 2 times per day, taking around 11h 1m. Cheap bus tickets for this journey start at $50 (€41) but you can travel from only $23 (€19) by flight.
The earliest bus runs at 00:45, the last at 23:15. The fastest bus covers the 367 miles (592 km) distance in 10h 5m.
Distance 367 miles (592 km) |
Average bus duration 11h 1m |
Cheapest ticket price $50 (€41) |
Buses per day 2 |
Fastest bus 10h 5m |
First bus 12:45 AM |
Last bus 11:15 PM |
Cheapest Month Aug |
Cheapest Day Thu |
High Season Apr - Jun |
Low Season Jul - Sep |
Best time to book 14 days |
Discover the best of Siena — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Siena trip today.
A vast former hospital complex opposite the cathedral, now a major museum with archaeological finds, frescoed halls, and temporary exhibitions.
The cathedral museum displaying Duomo treasures, sculptures by Giovanni Pisano, stained glass, and access to the Panorama dal Facciatone viewpoint.
Inside Palazzo Pubblico, this museum is famous for Ambrogio Lorenzetti's fresco cycle Allegory of Good and Bad Government.
Siena's shell-shaped main square is the social and visual heart of the city, famous for the Palio and essential for any visit.
A highly popular panoramic terrace above the unfinished cathedral facade, especially sought after for skyline photos and sunset views.
One of Siena's most elegant historic streets, lined with palaces, shops, and a steady flow of visitors between key monuments.
Thick hand-rolled Tuscan pasta served with a garlicky tomato sauce made with aglione, a traditional local garlic variety. It is one of Siena’s most iconic rustic dishes.
Pici pasta dressed simply with olive oil, garlic, chili, and toasted breadcrumbs. This classic Sienese preparation highlights peasant cooking traditions.
A hearty Tuscan soup of bread, cannellini beans, and vegetables, especially kale and cabbage. It is a beloved traditional comfort food in Siena and across Tuscany.
A celebrated traditional Sienese restaurant with vaulted cellars, famous for Tuscan specialties, pici, grilled meats, and a strong local wine list.
Elegant, long-established restaurant near Piazza del Campo known for refined Tuscan cooking, excellent wine, and a polished but welcoming atmosphere.
Historic restaurant set in atmospheric Etruscan-era rooms, offering classic Tuscan dishes with a slightly upscale style and memorable setting.
Moderate by Italian standards. Meals and coffee are reasonable, but hotels and dining cost more in peak season and near Piazza del Campo.
Service is often included or covered by a coperto. Tipping is not required, but rounding up or leaving 5-10% for good restaurant service is appreciated. Round up taxis.
Official public transport app
Siena Stazione FS, Piazzale Carlo Rosselli, Siena -> Piazza del Campo, Siena
Find answers to the most common questions about traveling from Grottaglie to Siena by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Siena, this guide helps you travel smarter and with confidence.

Most Grottaglie to Siena buses use the Grottaglie, Largo Unicef to Siena, Stazione FS (Piazzale Carlo Rosselli) station pair, with some services arriving at Siena, Siena/Viale Pietro Toselli. Use this guide to compare Grottaglie and Siena bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Here are some other resources that might have the information you need