The cheapest and fastest buses from San Francisco, CA to Santa Maria, CA
Cheapest price
$55
Average price
$55
Fastest journey
5 h
Average duration
5 h
Buses per day
1
Distance
361 km
The best way to find a cheap bus ticket from San Francisco, CA to Santa Maria, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from San Francisco, CA to Santa Maria, CA will cost around $55 if you buy it on the day, but the cheapest tickets can be found for only $55.
Of the 1 buses that leave San Francisco, CA for Santa Maria, CA on Fri, Nov 07, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Fri, Nov 07 the direct buses cover the 361 km distance in an average of 5 h but if you time it right, some buses will get you there in just 5 h .
On Fri, Nov 07 the slowest buses will take 5 h and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Travel Information
Compare bus and train for San Francisco, CA to Santa Maria, CA
Omio recommends booking the bus as it is the most popular option from San Francisco, CA to Santa Maria, CA among Omio's users. If you are prioritising price take the bus with prices starting from €22. For those with little time consider booking a bus which can get you there in 5h 10m. The ticket price range depends on the travel mode: a bus costs an average of €22, and a train costs an average of €58.
Distance: 224 miles (361 km)
Compare bus with
Most popular Bus | Train |
|---|---|
€42 Average price Cheapest | €69 Average price |
5h 40m Average total duration Fastest 5h 10m Onboard + 30m Additional time* | 11h 3m Average total duration 10h 33m Onboard + 30m Additional time* |
Direct Options | Direct Options |
Live departures
San Francisco, CA to Santa Maria, CA bus times
The table below shows live departures for San Francisco, CA to Santa Maria, CA buses for tomorrow, Friday, November 7. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 7:05 PM San Francisco, CA | 5h00 | 12:05 AM Santa Maria, CA | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets San Francisco, CA to Santa Maria, CA by bus or train
Compare bus and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Nov 07
Nov 08
Nov 09
Nov 10
Nov 11
Nov 12
Nov 13
Journey information
Overview: Bus from San Francisco, CA to Santa Maria, CA
Buses from San Francisco, CA to Santa Maria, CA run on average 6 times per day, taking around 5h 10m. Cheap bus tickets for this journey start at $27 (€22) if you book in advance.
There are 1 buses per day. The earliest bus runs at 06:30, the last at 23:35. The fastest bus covers the 224 miles (361 km) distance in 5h 0m.
Distance 224 miles (361 km) |
Average bus duration 5h 10m |
Cheapest ticket price $27 (€22) |
Buses per day 6 |
Direct buses 1 |
Fastest bus 5h 0m |
First bus 06:30 |
Last bus 23:35 |
Bus providers: FlixBus from San Francisco, CA to Santa Maria, CAYou can travel by bus between San Francisco, CA to Santa Maria, CA with FlixBus for as low as $27 (€22). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
FAQs: Bus from San Francisco, CA to Santa Maria, CA
Find answers to the most common questions about traveling from San Francisco, CA to Santa Maria, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Santa Maria, CA, this guide helps you travel smarter and with confidence.

- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
To find the cheapest bus tickets for your trip from San Francisco, CA to Santa Maria, CA, follow these tips:
Start your search now and compare ticket prices to find the best deal!
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- Guide dogs travel for free.
popular bus stations
Popular bus stations from San Francisco, CA to Santa Maria, CA
Most popular bus connections from San Francisco, CA
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