- Must visit
Museo del Prado
World-class art museum with masterpieces by Velázquez, Goya, and Bosch; essential for Spanish and European painting.
Cheapest price on Sep 20
€25
Average ticket price on Sep 20
€25
Fastest journey on Sep 20
3 h 55 m
Average journey duration on Sep 20
4 h
Buses on Sep 20
2
Distance
221 km
The best way to find a cheap bus ticket from Puerto de Santa Cruz to Madrid is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Puerto de Santa Cruz to Madrid will cost around €25 if you buy it on the day, but the cheapest tickets can be found for only €25.
On Sun, Sep 20, we found 2 buses from Puerto de Santa Cruz to Madrid, including 2 direct services.
On Sun, Sep 20 the direct buses cover the 221 km distance in an average of 4 h but if you time it right, some buses will get you there in just 3 h 55 m .
On Sun, Sep 20 the slowest buses will take 4 h 5 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.




Omio recommends booking the bus as it is the most popular option from Puerto de Santa Cruz to Madrid among Omio's users. If you are prioritising price, take the bus, with an average ticket price of €34 For those with little time, consider booking a bus, which has an average total journey time of 4h 55m. Average ticket prices depend on the travel mode: a bus costs an average of €34, while a bus costs an average of €34.
Distance: 137 miles (221 km)
Most popular Bus | Driving |
|---|---|
€34 Average price Cheapest | €45 Average price (fuel + tolls) |
4h 55m Average total duration Fastest 4h 25m Onboard + 30m Additional time* | 2h 32m Average total duration (door-to-door) |
![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options |
This is compared to other travel options from Puerto de Santa Cruz to Madrid:
A bus is €24 less than a flight for this route with tickets for a flight from Puerto de Santa Cruz to Madrid costing on average €58.
Other travel options to Madrid take longer:
Bus takes on average 4h 25m.
Tickets start at around €34 compared to roughly €45 in fuel and tolls — a saving of about €11. The journey takes 4h 25m versus 2h 32m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by Avanza.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Avanza | Departure Time 09:50AM | Arrival Time 02:15PM | Duration 4h25 | Departure days Thu | Cheapest price €33 |
Operator Avanza Grupo | Departure Time 10:50AM | Arrival Time 02:45PM | Duration 3h55 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price €25 |
Operator Avanza Grupo | Departure Time 06:00PM | Arrival Time 10:05PM | Duration 4h05 | Departure days Fri, Sun | Cheapest price €25 |
The table below shows live departures for Puerto de Santa Cruz to Madrid buses for today, Saturday, September 19. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 10:50 AM Puerto De Santa Cruz | 3h55 | 2:45 PM Madrid | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Puerto de Santa Cruz to Madrid run on average 1 times per day, taking around 4h 25m. Cheap bus tickets for this journey start at €34 but you can travel from only €22 by flight.
There are 1 buses per day. The earliest bus runs at 07:15, the last at 18:00. The fastest bus covers the 137 miles (221 km) distance in 4h 25m.
Distance 137 miles (221 km) |
Average bus duration 4h 25m |
Cheapest ticket price €34 |
Buses per day 1 |
Direct buses 1 |
Fastest bus 4h 25m |
First bus 7:15 AM |
Last bus 6:00 PM |
Cheapest Month Mar |
Cheapest Day Fri |
High Season Jan - Mar |
Low Season Oct - Dec |
Discover the best of Madrid — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Madrid trip today.
World-class art museum with masterpieces by Velázquez, Goya, and Bosch; essential for Spanish and European painting.
Leading modern art museum best known for Picasso’s Guernica, plus major works by Dalí and Miró.
Celebrated collection of European masters from Van Eyck to Hopper in a refined palace setting.
Madrid’s most famous park offers gardens, a boating lake, monuments, and relaxed walks in the city center.
Lively grand avenue known for architecture, shopping, theaters, and nonstop energy from day to night.
Elegant boulevard linking major museums and landmarks, ideal for a classic central Madrid walk.
A hearty chickpea stew with meats, vegetables, and broth, especially traditional in Madrid and often served in stages.
Crisp fried squid rings served in a baguette roll. This iconic Madrid street food is especially linked to bars around Plaza Mayor.
Tripe stew with chorizo and morcilla in a rich sauce. A classic old Madrid tavern dish with deep local roots.
Refined two-Michelin-star dining focused on seasonal Spanish produce, with elegant modern cooking in a polished fine-dining room.
Traditional Madrid restaurant known for cocido madrileño served in stages, with an old-school dining room and loyal local following.
Historic century-old tavern famed for roast suckling pig and Castilian dishes in a classic, wood-lined setting near Plaza Mayor.
Moderate for Western Europe: hotels vary, dining is reasonable, and public transport is good value for tourists.
Tipping is modest: round up or leave 5-10% in restaurants for good service. Taxis are usually rounded up. In cafés, small change is enough.
Official public transport app
Madrid Estación Sur de Autobuses -> Puerta del Sol
Find answers to the most common questions about traveling from Puerto de Santa Cruz to Madrid by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Madrid, this guide helps you travel smarter and with confidence.

Most Puerto de Santa Cruz to Madrid buses use the Puerto de Santa Cruz to Madrid, Estación Sur de Autobuses station pair. Use this guide to compare Puerto de Santa Cruz and Madrid bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Puerto de Santa Cruz has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Puerto de Santa Cruz. ATMs are available at Puerto de Santa Cruz.
Ticket office support is available at Puerto de Santa Cruz.
Available at Puerto de Santa Cruz: Parking, Taxis, WC.
Accessibility facilities are available at Puerto de Santa Cruz: Basic accessibility features for disabled passengers.
Madrid, Estación Sur de Autobuses is 3 km from Madrid city centre. Public transport options include:
Madrid, Estación Sur de Autobuses has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Cafetería de la estación (in the station), Restaurante El Brillante (0.5 km), La Taberna de Domínguez (0.7 km).
Free Wi-Fi. ATMs are located near the main entrance and in the waiting area.
Ticket office support is available at Madrid, Estación Sur de Autobuses.
Available at Madrid, Estación Sur de Autobuses: Parking, Taxis, WC.
Accessibility facilities are available at Madrid, Estación Sur de Autobuses: Elevators, ramps.
Here are some other resources that might have the information you need