The cheapest and fastest buses from Puerto de Santa Cruz to Madrid
Cheapest price
$26
Average price
$27
Fastest journey
3 h 52 m
Average duration
3 h 54 m
Buses per day
2
Distance
221 km
The best way to find a cheap bus ticket from Puerto de Santa Cruz to Madrid is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Puerto de Santa Cruz to Madrid will cost around $27 if you buy it on the day, but the cheapest tickets can be found for only $26.
Of the 2 buses that leave Puerto de Santa Cruz for Madrid on Tue, Dec 23, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Tue, Dec 23 the direct buses cover the 221 km distance in an average of 3 h 54 m but if you time it right, some buses will get you there in just 3 h 52 m .
On Tue, Dec 23 the slowest buses will take 3 h 55 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.




Live departures
Puerto de Santa Cruz to Madrid bus times
The table below shows live departures for Puerto de Santa Cruz to Madrid buses for today, Monday, December 22. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 10:50 AM Puerto De Santa Cruz | 3h52 | 2:42 PM Madrid | 1 transfer | |
![]() | 10:50 AM Puerto De Santa Cruz | 3h55 | 2:45 PM Madrid | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Puerto de Santa Cruz to Madrid by bus
Compare bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Dec 29
Journey information
Overview: Bus from Puerto de Santa Cruz to Madrid
Buses from Puerto de Santa Cruz to Madrid run on average 7 times per day, taking around 4h 5m. Cheap bus tickets for this journey start at $40 (€32) if you book in advance.
There are 7 buses per day. The earliest bus runs at 07:15, the last at 18:00. The fastest bus covers the 137 miles (221 km) distance in 4h 5m.
Distance 137 miles (221 km) |
Average bus duration 4h 5m |
Cheapest ticket price $40 (€32) |
Buses per day 7 |
Direct buses 7 |
Fastest bus 4h 5m |
First bus 07:15 |
Last bus 18:00 |
Bus providers: Avanza from Puerto de Santa Cruz to MadridYou can travel by bus between Puerto de Santa Cruz to Madrid with Avanza for as low as $40 (€32). When you search for schedules and tickets, Omio will show you the best journey
Avanza
FAQs: Bus from Puerto de Santa Cruz to Madrid
Find answers to the most common questions about traveling from Puerto de Santa Cruz to Madrid by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Madrid, this guide helps you travel smarter and with confidence.

Passengers board the bus most frequently from Puerto de Santa Cruz, which is located around 0.1 miles (183 m) away from the city centre, and they get off the bus at Madrid, Estación Sur de Autobuses, located 3.1 miles (5 km) away from the city centre.
- Avanza
- Assistance
- Priority boarding
- Accessible seating.
- Prado Museum, a renowned art museum housing European masterpieces from the 12th to the early 20th century
- Royal Palace of Madrid, the official residence of the Spanish royal family with opulent architecture and historical artifacts
- Retiro Park, a large and popular park in the city center featuring sculptures, a lake, and the Crystal Palace
- Plaza Mayor, a grand square surrounded by historic buildings and a hub for cultural events and markets
- Gran Vía, a bustling street known for its shopping, theaters, and vibrant nightlife.
- Puerta del Sol, a bustling public square known for its iconic clock and vibrant atmosphere
- Mercado de San Miguel, a historic market offering a variety of gourmet foods and traditional Spanish delicacies
- Explore the vibrant nightlife in the Malasaña district, known for its eclectic bars and live music venues
- Attend a flamenco show to experience traditional Spanish dance and music
- Visit the Santiago Bernabéu Stadium, home to Real Madrid, for a tour or to catch a football match.
- Avanza
- You can cancel your ticket up to 24 hours before departure for a partial refund. No refunds for cancellations within 24 hours.
To find the cheapest bus tickets for your trip from Puerto de Santa Cruz to Madrid, follow these tips:
Start your search now and compare ticket prices to find the best deal!
- Avanza
- One carry-on bag up to 10kg and one checked bag up to 25kg.
- Avanza
- Additional luggage can be purchased for a fee.
- Avanza
- Small pets allowed in carriers
- Guide dogs travel for free.
popular bus stations
Popular bus stations from Puerto de Santa Cruz to Madrid
- 06:00-23:00
- Free Wi-Fi
- Cafetería de la estación (in the station)
- Restaurante El Brillante (0.5 km)
- La Taberna de Domínguez (0.7 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 8, 102, 148 Metro: L6 Train: C1, C5
More options for your journey from Puerto de Santa Cruz to Madrid
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