- Must visit
Buffalo AKG Art Museum
Major regional art museum with modern, contemporary, and historic works, plus a growing campus and frequent exhibitions.
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The cheapest and fastest buses from Middletown, NY to Buffalo, NY
Showing times, prices and bookable tickets for Sep 20
Cheapest price on Sep 20
$149
Average ticket price on Sep 20
$164
Fastest journey on Sep 20
10 h 45 m
Average journey duration on Sep 20
10 h 45 m
Buses on Sep 20
2
Distance
401 km
Cheap tickets
The best way to find a cheap bus ticket from Middletown, NY to Buffalo, NY is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Middletown, NY to Buffalo, NY will cost around $164 if you buy it on the day, but the cheapest tickets can be found for only $149.
Fast buses
On Sun, Sep 20, we found 2 buses from Middletown, NY to Buffalo, NY, including 2 direct services.
On Sun, Sep 20 the direct buses cover the 401 km distance in an average of 10 h 45 m but if you time it right, some buses will get you there in just 10 h 45 m .
On Sun, Sep 20 the slowest buses will take 10 h 45 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
9:00 PM10h45Middletown, NY7:45 AMBuffalo, NY$1491One-way0 transfers- 10:00 PM10h45Middletown, NY8:45 AMBuffalo, NY$1781One-way0 transfers
- 10:00 PM10h45Middletown, NY8:45 AMBuffalo, NY$1781One-way0 transfers
- 9:00 PM10h45Middletown, NY7:45 AMBuffalo, NY$1491One-way0 transfers
Travel Information
Compare bus, train, and flight for Middletown, NY to Buffalo, NY
Omio recommends booking the train as it is the most popular option from Middletown, NY to Buffalo, NY among Omio's users. If you are prioritising price, take the train, with an average ticket price of $123 For those with little time, consider booking a flight, which has an average total journey time of 5h 49m. Average ticket prices depend on the travel mode: a train costs an average of $123, while a flight costs an average of $576.
Distance: 249 miles (401 km)
Compare bus with
| Bus | Most popular Train | Flight | Driving |
|---|---|---|---|
$159 Average price | $123 Average price Cheapest | $576 Average price | $77 Average price (fuel + tolls) |
10h 8m Average total duration 9h 38m Onboard + 30m Additional time* | 7h 36m Average total duration 7h 6m Onboard + 30m Additional time* | 5h 49m Average total duration Fastest 3h 49m Onboard + 2h 0m Additional time* | 5h 8m Average total duration (door-to-door) |
Most popular bus company |  Most popular train company |  Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
The cheapest way to travel from Middletown, NY to Buffalo, NY is a train with an average price of $123.
This is compared to other travel options from Middletown, NY to Buffalo, NY:
A train is $36 less than a bus for this route with tickets for a bus from Middletown, NY to Buffalo, NY costing on average $159.
A train is $453 less than a flight for this route with tickets for a flight from Middletown, NY to Buffalo, NY costing on average $576.
The fastest way to travel from Middletown, NY to Buffalo, NY is by flight with an average journey time of 3h 49m.
Other travel options to Buffalo, NY take longer:
Train takes on average 7h 6m.
Bus takes on average 9h 38m.
It's helpful to compare your options as there are 3 ways to travel between Middletown, NY and Buffalo, NY including taking a bus, train, and flight.
We recommend using the flight as it is the most popular way to get from Middletown, NY to Buffalo, NY among Omio's users.
Take the bus. It's the cheapest way to make this trip, and the price gap is usually bigger than people expect.
Tickets start at around $159 compared to roughly $77 in fuel and tolls — a saving of about $-81.64. The journey takes 9h 38m versus 5h 8m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
Middletown, NY to Buffalo, NY Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Shortline Bus | Departure Time 05:30AM | Arrival Time 04:20PM | Duration 10h50 | Departure days Mon, Tue, Wed, Thu | Cheapest price $84 |
Operator Shortline Bus | Departure Time 06:45AM | Arrival Time 06:30PM | Duration 11h45 | Departure days Sat | Cheapest price $207 |
Operator Shortline Bus | Departure Time 08:05AM | Arrival Time 06:30PM | Duration 10h25 | Departure days Mon, Tue, Wed, Thu | Cheapest price $207 |
Operator Shortline Bus | Departure Time 10:15AM | Arrival Time 06:50PM | Duration 8h35 | Departure days Mon, Tue, Wed, Thu, Sat | Cheapest price $77 |
Operator Shortline Bus | Departure Time 01:20PM | Arrival Time 04:00AM | Duration 14h40 | Departure days Mon, Tue, Wed, Thu | Cheapest price $207 |
Operator Shortline Bus | Departure Time 03:45PM | Arrival Time 04:00AM | Duration 12h15 | Departure days Sat | Cheapest price $207 |
Operator Shortline Bus | Departure Time 06:57PM | Arrival Time 04:00AM | Duration 9h03 | Departure days Mon, Tue, Wed, Thu | Cheapest price $147 |
Operator Adirondack Trailways | Departure Time 09:00PM | Arrival Time 07:45AM | Duration 10h45 | Departure days Fri, Sun | Cheapest price $149 |
Operator Adirondack Trailways | Departure Time 10:00PM | Arrival Time 08:45AM | Duration 10h45 | Departure days Fri, Sun | Cheapest price $178 |
Live departures
Middletown, NY to Buffalo, NY bus times
The table below shows live departures for Middletown, NY to Buffalo, NY buses for today, Saturday, September 19. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
 | 6:45 AM Middletown, NY | 11h45 | 6:30 PM Buffalo, NY | 1 transfer | |
| 10:15 AM Middletown, NY | 8h35 | 6:50 PM Buffalo, NY | 2 transfers | |
| 3:45 PM Middletown, NY | 12h15 | 4:00 AM Buffalo, NY | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Middletown, NY to Buffalo, NY by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Bus from Middletown, NY to Buffalo, NY
USAUSA
Buses from Middletown, NY to Buffalo, NY run on average 2 times per day, taking around 9h 38m. Cheap bus tickets for this journey start at $132 but you can travel from only $84 by train.
The earliest bus runs at 06:00, the last at 23:15. The fastest bus covers the 249 miles (401 km) distance in 9h 0m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Train from $84
Distance 249 miles (401 km) |
Average bus duration 9h 38m |
Cheapest ticket price $132 |
Buses per day 2 |
Fastest bus 9h 0m |
First bus 6:00 AM |
Last bus 11:15 PM |
Cheapest Month May |
Cheapest Day Sun |
High Season Oct - Dec |
Low Season Apr - Jun |
Busiest Day Sun |
Least Busy Day Sun |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Train from $84
Bus providers: Adirondack Trailways, New York Trailways from Middletown, NY to Buffalo, NYYou can travel by bus between Middletown, NY to Buffalo, NY with Adirondack Trailways, New York Trailways for as low as $84. When you search for schedules and tickets, Omio will show you the best journey
Adirondack Trailways
Luggage & cancellation policy
Average Adirondack Trailways Duration
9h 40m
Cheapest Adirondack Trailways Price
$152
Adirondack Trailways frequency
2 a day
New York Trailways
Luggage & cancellation policy
Average New York Trailways Duration
9h 0m
Cheapest New York Trailways Price
$132
New York Trailways frequency
2 a day
Complete guide to Buffalo, NY
Things to do in Buffalo, NY
Discover the best of Buffalo, NY — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Buffalo, NY trip today.
- Recommended
Theodore Roosevelt Inaugural National Historic Site
Former presidential inaugural site with exhibits on Theodore Roosevelt, the Pan-American Exposition, and Buffalo politics.
- Recommended
Michigan Street African American Heritage Corridor
Community museum preserving Buffalo’s African American heritage through local history, culture, and rotating exhibitions.
- Must visit
Canalside
Waterfront district with canal history, public art, seasonal events, skating, and frequent family-friendly activities downtown.
- Must visit
Elmwood Village
Lively walkable neighborhood known for boutiques, galleries, architecture, and one of Buffalo’s most popular main streets.
- Must visit
Outer Harbor
Long urban trail and greenway connecting waterfront areas, parks, and neighborhoods for walking, biking, and sightseeing.
Buffalo Wings
Crisp fried chicken wings coated in spicy butter-hot sauce. Created in Buffalo, they are the city’s signature bar food and a must-try local classic.
Beef On Weck
Thin-sliced roast beef on a kummelweck roll topped with coarse salt and caraway, usually dipped in jus. It is a longtime Western New York sandwich staple.
- Gluten-free
Buffalo-Style Bean Soup
Slow-cooked bean soup with ham, tomatoes, and vegetables. It is strongly associated with Buffalo’s old taverns and Friday lunch traditions.
Oliver's Restaurant
Refined fine-dining restaurant known for seasonal New American tasting menus, polished service, and an elegant special-occasion atmosphere.
Schwabl's
Traditional German restaurant celebrated for beef on weck, sausages, and old-world charm. A Buffalo dining landmark with a cozy historic feel.
Duff's Famous Wings
Long-standing wing institution known for crispy, saucy chicken wings in a classic neighborhood bar setting with a devoted local following.
United States dollar ($)
Moderate for U.S. city travel; hotels are often cheaper than NYC, while dining and local transit stay fairly manageable for visitors.
Average meal costs
- Budget
- $10-18 for fast food or casual takeout.
- Mid-range
- $20-40 per person for a mid-range restaurant meal.
- Fine dining
- $60+ per person for upscale dining.
- Coffee
- $3-6 for a coffee or cappuccino.
Tipping culture
Tip 18-20% at restaurants, more for great service. Taxis usually 10-15%. For cafes, round up or add $1 per drink.
FAQs: Bus from Middletown, NY to Buffalo, NY
Find answers to the most common questions about traveling from Middletown, NY to Buffalo, NY by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Buffalo, NY, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Middletown, NY to Buffalo, NY can start from as little as $132 when you book in advance. The average bus ticket price for Middletown, NY to Buffalo, NY is $159 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Middletown, NY to Buffalo, NY is 9h 0m to travel the 249 miles (401 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Middletown, NY to Buffalo, NY leaves at 6:00 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Middletown, NY to Buffalo, NY leaves at 11:15 PM.
There are 2 buses a day from Middletown, NY to Buffalo, NY which require at least one change with New York Trailways, Adirondack Trailways. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Middletown, NY to Buffalo, NY, you can count on New York Trailways, Adirondack Trailways for the best way to get you to Buffalo, NY. You can also check all possible bus companies who offer a service between Middletown, NY and Buffalo, NY and compare the amenities they offer before buying a bus ticket.
When departing from Middletown, NY , you have various bus station options to start your journey from including Middletown, Crystal Run Road (Exit 122 Park & Ride), NY . When arriving in Buffalo, NY , you can end your journey in bus stations like Buffalo, NFTA Metro Center, Cheektowaga, BNIA Drway & BNIA Terminal .Passengers board the bus most frequently from Middletown, Crystal Run Road (Exit 122 Park & Ride), NY, which is located around 3 miles (5 km) away from the city centre, and they get off the bus at Buffalo, NFTA Metro Center, located 0 away from the city centre.
A trip to Buffalo, NY from Middletown, NY is worth doing but not as a day trip with a journey time of 9h 0m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Middletown, NY to Buffalo, NY is May.
It's helpful to compare your options as there are 3 ways to travel between Middletown, NY and Buffalo, NY including taking a bus, train, and flight.
No, there are no bathrooms on board the bus from Middletown, NY to Buffalo, NY.
No, the bus from Middletown, NY to Buffalo, NY has no accessibility options.
No, bikes are not allowed on board the bus from Middletown, NY to Buffalo, NY.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
No, there is no food available to purchase on board the bus from Middletown, NY to Buffalo, NY.
No, luggage for the bus from Middletown, NY to Buffalo, NY needs to be booked in addition.
No, there are no additional luggage options for the bus from Middletown, NY to Buffalo, NY.
Unfortunately, pets are not allowed on the bus from Middletown, NY to Buffalo, NY.
No, there are no USB plugs on board the bus from Middletown, NY to Buffalo, NY.
No, there is no WiFi on board the bus from Middletown, NY to Buffalo, NY.
Since neither Middletown, NY nor Buffalo, NY are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the flight as it is the most popular way to get from Middletown, NY to Buffalo, NY among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Buffalo, NY, travelers should be cautious of pickpocketing and petty theft, especially in crowded areas like downtown and tourist spots. Scams involving overcharging for taxi or rideshare services have been reported, so it's advised to use licensed transportation and confirm fares beforehand. Additionally, travelers should stay aware of their surroundings at night, particularly in less populated neighborhoods, to avoid potential safety risks.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Middletown, NY to Buffalo, NY
Most Middletown, NY to Buffalo, NY buses use the Middletown, Crystal Run Road (Exit 122 Park & Ride) to Cheektowaga, BNIA Drway & BNIA Terminal station pair, with some services arriving at Buffalo, NFTA Metro Center. Use this guide to compare Middletown, NY and Buffalo, NY bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in Middletown
Arrival bus stations in Buffalo
Which Middletown, NY station do buses to Buffalo, NY leave from?
Buses from Middletown, NY to Buffalo, NY leave from Middletown, Crystal Run Road (Exit 122 Park & Ride). The station is 3 miles (5 km) from Middletown, NY city centre at Crystal Run Rd, Middletown, NY 10941, USA.
Middletown, Crystal Run Road (Exit 122 Park & Ride)Crystal Run Rd, Middletown, NY 10941, USA
City-centre transport
Getting to Middletown, Crystal Run Road (Exit 122 Park & Ride) from Middletown city centre
Middletown, Crystal Run Road (Exit 122 Park & Ride) is 5 km from Middletown city centre. Public transport options include:
Bus3 · 36m · $5
Middletown, Crystal Run Road (Exit 122 Park & Ride) bus station facilities and services
Middletown, Crystal Run Road (Exit 122 Park & Ride) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Middletown, Crystal Run Road (Exit 122 Park & Ride). ATMs are available at Middletown, Crystal Run Road (Exit 122 Park & Ride).
Tickets and information
Ticket office support is available at Middletown, Crystal Run Road (Exit 122 Park & Ride).
Parking, taxis and toilets
Available at Middletown, Crystal Run Road (Exit 122 Park & Ride): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Middletown, Crystal Run Road (Exit 122 Park & Ride): Wheelchair accessible parking and ramps available.
Which Buffalo, NY station do buses from Middletown, NY arrive at?
Buses from Middletown, NY to Buffalo, NY most often arrive at Buffalo, NFTA Metro Center. Some services arrive at Cheektowaga, BNIA Drway & BNIA Terminal, so check your ticket before travel to confirm your Buffalo, NY arrival station.
Buffalo, NFTA Metro CenterBuffalo, NY, USA
City-centre transport
Getting to Buffalo, NFTA Metro Center from Buffalo city centre
TRUE
Buffalo, NFTA Metro Center bus station facilities and services
Buffalo, NFTA Metro Center has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Free WiFi is available in the station. ATMs are aTM services are available near the entrance.
Tickets and information
Ticket office support is available at Buffalo, NFTA Metro Center.
Parking, taxis and toilets
Available at Buffalo, NFTA Metro Center: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Buffalo, NFTA Metro Center: Accessible for passengers with reduced mobility.
Cheektowaga, BNIA Drway & BNIA Terminal
City-centre transport
Getting to Cheektowaga, BNIA Drway & BNIA Terminal from Buffalo city centre
BusAdt N809 · 10m · $7
24, 78 · 31m · $2 · every ~4 min
24, 78 · 46m · $2 · every ~4 min
More options for your journey from Middletown, NY to Buffalo, NY
Here are some other resources that might have the information you need
Most popular buses to and from Buffalo, NY and Middletown, NY
Most popular bus connections to Buffalo, NY
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