- Must visit
Buffalo AKG Art Museum
Major regional art museum with modern, contemporary, and historic works, plus a growing campus and frequent exhibitions.
2,000+ travel companies
2,000+ travel companies
Scan to get our free app
Use our app to get live travel updates and book mobile tickets for trains, buses, flights, and ferries.
App Store
4.942K ratings
Google Play
4.6136K reviews
Journey information
Overview: Bus from Middletown, PA to Buffalo, NY
USAUSA
Take a bus from Middletown, PA to Buffalo, NY and enjoy the approximately 216 miles (348 km) long journey. Find schedules and pricing options for a convenient and affordable trip.
The earliest bus runs at 00:55, the last at 23:20.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 216 miles (348 km) |
First bus 12:55 AM |
Last bus 11:20 PM |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Complete guide to Buffalo, NY
Things to do in Buffalo, NY
Discover the best of Buffalo, NY — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Buffalo, NY trip today.
- Recommended
Theodore Roosevelt Inaugural National Historic Site
Former presidential inaugural site with exhibits on Theodore Roosevelt, the Pan-American Exposition, and Buffalo politics.
- Recommended
Michigan Street African American Heritage Corridor
Community museum preserving Buffalo’s African American heritage through local history, culture, and rotating exhibitions.
- Must visit
Canalside
Waterfront district with canal history, public art, seasonal events, skating, and frequent family-friendly activities downtown.
- Must visit
Elmwood Village
Lively walkable neighborhood known for boutiques, galleries, architecture, and one of Buffalo’s most popular main streets.
- Must visit
Outer Harbor
Long urban trail and greenway connecting waterfront areas, parks, and neighborhoods for walking, biking, and sightseeing.
Buffalo Wings
Crisp fried chicken wings coated in spicy butter-hot sauce. Created in Buffalo, they are the city’s signature bar food and a must-try local classic.
Beef On Weck
Thin-sliced roast beef on a kummelweck roll topped with coarse salt and caraway, usually dipped in jus. It is a longtime Western New York sandwich staple.
- Gluten-free
Buffalo-Style Bean Soup
Slow-cooked bean soup with ham, tomatoes, and vegetables. It is strongly associated with Buffalo’s old taverns and Friday lunch traditions.
Oliver's Restaurant
Refined fine-dining restaurant known for seasonal New American tasting menus, polished service, and an elegant special-occasion atmosphere.
Schwabl's
Traditional German restaurant celebrated for beef on weck, sausages, and old-world charm. A Buffalo dining landmark with a cozy historic feel.
Duff's Famous Wings
Long-standing wing institution known for crispy, saucy chicken wings in a classic neighborhood bar setting with a devoted local following.
United States dollar ($)
Moderate for U.S. city travel; hotels are often cheaper than NYC, while dining and local transit stay fairly manageable for visitors.
Average meal costs
- Budget
- $10-18 for fast food or casual takeout.
- Mid-range
- $20-40 per person for a mid-range restaurant meal.
- Fine dining
- $60+ per person for upscale dining.
- Coffee
- $3-6 for a coffee or cappuccino.
Tipping culture
Tip 18-20% at restaurants, more for great service. Taxis usually 10-15%. For cafes, round up or add $1 per drink.
FAQs: Bus from Middletown, PA to Buffalo, NY
Find answers to the most common questions about traveling from Middletown, PA to Buffalo, NY by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Buffalo, NY, this guide helps you travel smarter and with confidence.
popular bus stations
Popular bus stations from Middletown, PA to Buffalo, NY
Most Middletown, PA to Buffalo, NY buses use the Harrisburg, Market St (Bus Station) to Buffalo, NFTA Metro Center station pair, with some services arriving at Cheektowaga, BNIA Drway & BNIA Terminal. Use this guide to compare Middletown, PA and Buffalo, NY bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in Middletown
Arrival bus stations in Buffalo
Which Middletown, PA station do buses to Buffalo, NY leave from?
Buses from Middletown, PA to Buffalo, NY leave from Harrisburg, Market St (Bus Station). The station is 0 miles (1 km) from Middletown, PA city centre at Harrisburg, 411 Market St, Harrisburg, PA 17101, USA.
Middletown, Terminal Dr (Harrisburg Airport)Harrisburg International Airport (MDT), 1 Terminal Dr, Middletown, PA 17057, USA
City-centre transport
Getting to Middletown, Terminal Dr (Harrisburg Airport) from Middletown city centre
Middletown, Terminal Dr (Harrisburg Airport) is 2 km from Middletown city centre. Public transport options include:
Bus7 · 5m · $2 · every ~3 min
7 · 7m · $2 · every ~3 min
7 · 8m · $2 · every ~3 min
7 · 22m · $2 · every ~3 min
Middletown, Terminal Dr (Harrisburg Airport) bus station facilities and services
Middletown, Terminal Dr (Harrisburg Airport) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Middletown, Terminal Dr (Harrisburg Airport). ATMs are available at Middletown, Terminal Dr (Harrisburg Airport).
Tickets and information
Ticket office support is available at Middletown, Terminal Dr (Harrisburg Airport).
Parking, taxis and toilets
Available at Middletown, Terminal Dr (Harrisburg Airport): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Middletown, Terminal Dr (Harrisburg Airport): Wheelchair accessible via airport facilities.
Middletown, Harrisburg International AirportHarrisburg International Airport (MDT), 1 Terminal Dr, Middletown, PA 17057, USA
City-centre transport
Getting to Middletown, Harrisburg International Airport from Middletown city centre
Middletown, Harrisburg International Airport is 2 km from Middletown city centre. Public transport options include:
TRUE
Middletown, Harrisburg International Airport bus station facilities and services
Middletown, Harrisburg International Airport has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Middletown, Harrisburg International Airport. ATMs are aTM located near the entrance.
Tickets and information
Ticket office support is available at Middletown, Harrisburg International Airport.
Parking, taxis and toilets
Available at Middletown, Harrisburg International Airport: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Middletown, Harrisburg International Airport: Wheelchair accessible facilities present.
Which Buffalo, NY station do buses from Middletown, PA arrive at?
Buses from Middletown, PA to Buffalo, NY most often arrive at Buffalo, NFTA Metro Center. Some services arrive at Cheektowaga, BNIA Drway & BNIA Terminal, so check your ticket before travel to confirm your Buffalo, NY arrival station.
Buffalo, NFTA Metro CenterBuffalo, NY, USA
City-centre transport
Getting to Buffalo, NFTA Metro Center from Buffalo city centre
TRUE
Buffalo, NFTA Metro Center bus station facilities and services
Buffalo, NFTA Metro Center has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Free WiFi is available in the station. ATMs are aTM services are available near the entrance.
Tickets and information
Ticket office support is available at Buffalo, NFTA Metro Center.
Parking, taxis and toilets
Available at Buffalo, NFTA Metro Center: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Buffalo, NFTA Metro Center: Accessible for passengers with reduced mobility.
Cheektowaga, BNIA Drway & BNIA Terminal
City-centre transport
Getting to Cheektowaga, BNIA Drway & BNIA Terminal from Buffalo city centre
BusAdt N809 · 10m · $7
24, 78 · 31m · $2 · every ~4 min
24, 78 · 46m · $2 · every ~4 min
BuffaloBuffalo Bus, Buffalo, NY 14203, USA
City-centre transport
Getting to Buffalo from Buffalo city centre
TrainEmpire Service, Maple Leaf · 17m · $23
Buffalo bus station facilities and services
Buffalo has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Snack bar available inside the station.
Wi-Fi and ATMs
Free wifi available throughout the station. ATMs are aTM located near the main entrance.
Tickets and information
Ticket office support is available at Buffalo.
Parking, taxis and toilets
Available at Buffalo: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Buffalo: Station is wheelchair accessible.
More options for your journey from Middletown, PA to Buffalo, NY
Here are some other resources that might have the information you need
Most popular buses to and from Buffalo, NY and Middletown, PA
Most popular bus connections to Buffalo, NY
The Omio App Makes Travel Planning Easy
We’ll get you where you want to go. From live train updates to mobile tickets, our innovative app is the ideal way to plan and keep track of your travel.
