Travel Information
Compare bus, train, and flight for Messina to Milan
Omio recommends booking the bus as it is the most popular option from Messina to Milan among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $103 For those with little time, consider booking a flight, which has an average total journey time of 4h 20m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.3 - 0.9kg. Average ticket prices depend on the travel mode: a bus costs an average of $103, while a flight costs an average of $329.
Distance: 599 miles (964 km)
Compare bus with
Most popular Bus | Train | Flight | Driving |
|---|---|---|---|
$103 Average price Cheapest | $159 Average price | $329 Average price | $323 Average price (fuel + tolls) |
18h 40m Average total duration 18h 10m Onboard + 30m Additional time* | 15h 34m Average total duration 15h 4m Onboard + 30m Additional time* | 4h 20m Average total duration Fastest 2h 20m Onboard + 2h 0m Additional time* | 12h 43m Average total duration (door-to-door) |
1.0 - 2.4kg CO2 emissions | 0.3 - 0.9kg CO2 emissions Lowest | 2.9 - 5.8kg CO2 emissions | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Compare ways to travel from Messina to Milan
Compare the available ways to get from Messina to Milan, with the key details around price, speed, convenience, and direct service.
This is compared to other travel options from Messina to Milan:
A bus is $56 (€47) less than a train for this route with tickets for a train from Messina to Milan costing on average $159 (€134).
A bus is $226 (€190) less than a flight for this route with tickets for a flight from Messina to Milan costing on average $329 (€276).
Other travel options to Milan take longer:
Train takes on average 15h 34m.
Bus takes on average 18h 40m.
Tickets start at around $103 (€87) compared to roughly $323 (€271) in fuel and tolls — a saving of about $220 (€185). The journey takes 18h 10m versus 12h 43m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
Travel optionsfrom Messina to Milan
How to get from Messina to Milan by train, bus or flight.
Our recommendation
The best way to travel from Messina to Milan is by taking a bus because it’s the best combination of price and speed.
21269:35 PM 19h05 Messina, Piazza Della Repubblica (Stazione Centrale) 4:40 PM Milano, Autostazione Lampugnano $84 1 One-way 0 transfers
Cheapest
21269:35 PM 19h05 Messina, Piazza Della Repubblica (Stazione Centrale) 4:40 PM Milano, Autostazione Lampugnano $84 1 One-way 0 transfers
Fastest
FlixBus8:15 PM 17h30 Messina, Piazza Della Repubblica (Stazione Centrale) 1:45 PM Milano, Autostazione Lampugnano $101 1 One-way 0 transfers
Other options
FlixBus10:55 AM 18h20 Messina, Piazza Della Repubblica (Stazione Centrale) 5:15 AM Milano, San Donato - Settore B (Viale Giuseppe Impastato) $158 1 One-way 0 transfers
FlixBus10:55 AM 19h00 Messina, Piazza Della Repubblica (Stazione Centrale) 5:55 AM Milano, Autostazione Lampugnano $158 1 One-way 0 transfers
FlixBus · FlixBus8:15 PM 18h20 Messina, Piazza Della Repubblica (Stazione Centrale) 2:35 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) $167 1 One-way 1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
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FAQs: Travel from Messina to Milan
Travel to Milan easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Messina to Milan.

This is compared to other travel options from Messina to Milan:
A bus is $56 (€47) less than a train for this route with tickets for a train from Messina to Milan costing on average $159 (€134).
A bus is $226 (€190) less than a flight for this route with tickets for a flight from Messina to Milan costing on average $329 (€276).
Other travel options to Milan take longer:
Train takes on average 15h 34m.
Bus takes on average 18h 40m.
- Around 11 trains per day.
- Around 11 buses per day.
- Around 5 flights per day.
However, we recommend checking specific travel dates for your route between Messina and Milan as scheduled services by bus, train, and flight can vary by season or day of the week.
- Flights mostly depart from Catania Fontanarossa Airport and arrive in Milan Malpensa Airport.
- Trains mostly depart from Messina Centrale and arrive in Milan Centrale.
- Buses mostly depart from Messina, Piazza Della Repubblica (Stazione Centrale) and arrive in Milano, Autostazione Lampugnano.
- Travel with FlixBus, Itabus, Salemi to go to Milan by bus.
- Travel with Intercity Notte, Intercity, Frecciarossa to go to Milan by train.
- Travel with Aeroitalia, easyJet, Eurowings to go to Milan by flight.
- 4 direct buses per day with FlixBus, Itabus.
- 1 direct trains per day with Intercity Notte.
- 3 direct flights per day with Aeroitalia, easyJet.
Travelling from Messina to Milan: related information
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