Travel Information
Compare train and bus for Mendrisio to Florence
Omio recommends booking the train as it is the most popular option from Mendrisio to Florence among Omio's users. If you are prioritising price take the bus with prices starting from $37. For those with little time consider booking a train which can get you there in 4h 48m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.3kg. The ticket price range depends on the travel mode: a bus costs an average of $37, and a train costs an average of $37.
Distance: 182 miles (294 km)
Compare bus with
| Bus | Most popular Train |
|---|---|
$37 Average price Cheapest | $37 Average price |
7h 50m Average total duration 7h 20m Onboard + 30m Additional time* | 5h 18m Average total duration Fastest 4h 48m Onboard + 30m Additional time* |
0.3 - 0.7kg CO2 emissions | 0.1 - 0.3kg CO2 emissions Lowest |
Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Compare prices and tickets Mendrisio to Florence by train or bus
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Mar 23
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Journey information
Overview: Bus from Mendrisio to Florence
Buses from Mendrisio to Florence run on average 11 times per day, taking around 7h 20m. Cheap bus tickets for this journey start at $37 (€30) but you can travel from only $37 (€30) by train.
There are 7 buses per day. The earliest bus runs at 00:50, the last at 23:40. The fastest bus covers the 182 miles (294 km) distance in 7h 20m.
Distance 182 miles (294 km) |
Average bus duration 7h 20m |
Cheapest ticket price $37 (€30) |
Buses per day 11 |
Direct buses 7 |
Fastest bus 7h 20m |
First bus 00:50 |
Last bus 23:40 |
Cheapest month Mar |
Cheapest day Mon |
High season Jul - Sep |
Low season Apr - Jun |
Busiest day Thu |
Least busy day Thu |
Best day to book ahead 63 days |
FAQs: Bus from Mendrisio to Florence
Find answers to the most common questions about traveling from Mendrisio to Florence by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Florence, this guide helps you travel smarter and with confidence.

- Florence Cathedral, an iconic Gothic structure known for its stunning dome designed by Brunelleschi
- Uffizi Gallery, a renowned art museum housing masterpieces by artists like Botticelli and Michelangelo
- Ponte Vecchio, a historic bridge famous for its shops and picturesque views over the Arno River
- Palazzo Vecchio, a medieval fortress-palace that serves as Florence's town hall and a museum
- Boboli Gardens, a vast and elegant park behind Pitti Palace featuring sculptures and fountains.
- Climb to Piazzale Michelangelo, a popular spot offering panoramic views of Florence's skyline
- Visit the Accademia Gallery to see Michelangelo's David
- Take a cooking class to learn how to make traditional Tuscan dishes
- Enjoy a wine tasting tour in the Chianti region
- Explore the vibrant San Lorenzo Market for local goods and delicacies.
popular bus stations
Popular bus stations from Mendrisio to Florence
- 06:00-22:00
- Free Wi-Fi
- Elevators, ramps
- Available in the station.
- Bus: 37, 72 Tram: T1
- 06:00-21:00
- Free Wi-Fi
- Available near the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 12, 13, 17 Train: Firenze Santa Maria Novella
More options for your journey from Mendrisio to Florence
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