The cheapest and fastest buses from Mendrisio to Florence
Cheapest price
$58
Average price
$58
Fastest journey
7 h 10 m
Average duration
7 h 10 m
Buses per day
1
Distance
294 km
The best way to find a cheap bus ticket from Mendrisio to Florence is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Mendrisio to Florence will cost around $58 if you buy it on the day, but the cheapest tickets can be found for only $58.
Of the 1 buses that leave Mendrisio for Florence on Thu, Feb 05, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Thu, Feb 05 the direct buses cover the 294 km distance in an average of 7 h 10 m but if you time it right, some buses will get you there in just 7 h 10 m .
On Thu, Feb 05 the slowest buses will take 7 h 10 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Compare prices and tickets Mendrisio to Florence by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Bus from Mendrisio to Florence
Take a bus from Mendrisio to Florence and enjoy the approximately 182 miles (294 km) long journey. Find schedules and pricing options for a convenient and affordable trip.
There are 7 buses per day. The earliest bus runs at 00:05, the last at 23:40.
Distance 182 miles (294 km) |
Buses per day 11 |
Direct buses 7 |
First bus 00:05 |
Last bus 23:40 |
FAQs: Bus from Mendrisio to Florence
Find answers to the most common questions about traveling from Mendrisio to Florence by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Florence, this guide helps you travel smarter and with confidence.

- Florence Cathedral, an iconic Gothic structure known for its stunning dome designed by Brunelleschi
- Uffizi Gallery, a renowned art museum housing masterpieces by artists like Botticelli and Michelangelo
- Ponte Vecchio, a historic bridge famous for its shops and picturesque views over the Arno River
- Palazzo Vecchio, a medieval fortress-palace that serves as Florence's town hall and a museum
- Boboli Gardens, a vast and elegant park behind Pitti Palace featuring sculptures and fountains.
- Climb to Piazzale Michelangelo, a popular spot offering panoramic views of Florence's skyline
- Visit the Accademia Gallery to see Michelangelo's David
- Take a cooking class to learn how to make traditional Tuscan dishes
- Enjoy a wine tasting tour in the Chianti region
- Explore the vibrant San Lorenzo Market for local goods and delicacies.
popular bus stations
Popular bus stations from Mendrisio to Florence
- 06:00-22:00
- Free Wi-Fi
- Elevators, ramps
- Available in the station.
- Bus: 37, 72 Tram: T1
- 06:00-21:00
- Free Wi-Fi
- Available near the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 12, 13, 17 Train: Firenze Santa Maria Novella
More options for your journey from Mendrisio to Florence
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