Travel Information
Compare train and bus for Mendrisio to Florence
Omio recommends booking the train as it is the most popular option from Mendrisio to Florence among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $50 For those with little time, consider booking a train, which has an average total journey time of 3h 9m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.1 - 0.3kg. Average ticket prices depend on the travel mode: a bus costs an average of $50, while a flight costs an average of $356.
Distance: 182 miles (294 km)
Compare train with
Most popular Train | Flight | Bus | Driving |
|---|---|---|---|
$57 Average price | $356 Average price | $50 Average price Cheapest | $79 Average price (fuel + tolls) |
3h 9m Average total duration Fastest 2h 39m Onboard + 30m Additional time* | 4h 54m Average total duration 2h 54m Onboard + 2h 0m Additional time* | 6h 21m Average total duration 5h 51m Onboard + 30m Additional time* | 4h 6m Average total duration (door-to-door) |
0.1 - 0.3kg CO2 emissions Lowest | 0.9 - 1.8kg CO2 emissions | 0.3 - 0.7kg CO2 emissions | - CO2 emissions |
![]() Most popular train company | ![]() Most popular airline | ![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Compare ways to travel from Mendrisio to Florence
Compare the available ways to get from Mendrisio to Florence, with the key details around price, speed, convenience, and direct service.
This is compared to other travel options from Mendrisio to Florence:
A bus is $8 less than a train for this route with tickets for a train from Mendrisio to Florence costing on average $57.
A bus is $307 less than a flight for this route with tickets for a flight from Mendrisio to Florence costing on average $356.
Other travel options to Florence take longer:
Flight takes on average 4h 54m.
Bus takes on average 6h 21m.
The journey is about 1h 27m faster (2h 39m by train vs 4h 6m by car) and roughly $22 cheaper once you factor in fuel and tolls ($57 vs $79). You'll also arrive in the city centre rather than hunting for parking, and you can work, read, or watch the landscape go by instead of concentrating on the road.
Driving is still worth considering if you want to stop along the way or need a car once you arrive.
Compare prices and tickets Prices for trains, buses and flights
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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FAQs: Travel from Mendrisio to Florence
Travel to Florence easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Mendrisio to Florence.

This is compared to other travel options from Mendrisio to Florence:
A bus is $8 less than a train for this route with tickets for a train from Mendrisio to Florence costing on average $57.
A bus is $307 less than a flight for this route with tickets for a flight from Mendrisio to Florence costing on average $356.
Other travel options to Florence take longer:
Flight takes on average 4h 54m.
Bus takes on average 6h 21m.
- Around 32 trains per day.
- Around 14 flights per day.
- Around 12 buses per day.
However, we recommend checking specific travel dates for your route between Mendrisio and Florence as scheduled services by train and bus can vary by season or day of the week.
- Buses mostly depart from Como, Piazzale San Gottardo (Stazione San Giovanni) and arrive in Scandicci, Villa Costanza (Florence).
- Trains mostly depart from Milan Centrale and arrive in Florence Santa Maria Novella.
- Flights mostly depart from Milan Linate Airport and arrive in Florence Peretola Airport.
- Travel with FlixBus, Marino Autolinee, Itabus to go to Florence by bus.
- Travel with Italo, Frecciarossa, Regionale, Intercity, Intercity Notte to go to Florence by train.
- Travel with ITA to go to Florence by flight.
- 7 direct buses per day with FlixBus, Marino Autolinee, Itabus.
- 22 direct trains per day with Italo.
Travelling from Mendrisio to Florence: related information
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