Travel optionsfrom Mendrisio to Florence
How to get from Mendrisio to Florence by train, bus or flight.
Our recommendation
The best way to travel from Mendrisio to Florence is by taking a train because it’s the best combination of price and speed.
7:18 AM3h17Mendrisio10:35 AMFlorence$1191One-way1 transfer
Cheapest
7:18 AM3h17Mendrisio10:35 AMFlorence$1191One-way1 transfer
Fastest
7:18 AM3h17Mendrisio10:35 AMFlorence$1191One-way1 transfer
Other options
8:18 AM3h17Mendrisio11:35 AMFlorence$1191One-way1 transfer
10:18 AM3h17Mendrisio1:35 PMFlorence$1191One-way1 transfer
12:18 PM3h17Mendrisio3:35 PMFlorence$1191One-way1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
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FAQs: Travel from Mendrisio to Florence
Travel to Florence easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Mendrisio to Florence.

This is compared to other travel options from Mendrisio to Florence:
A train is 0 less than a bus for this route with tickets for a bus from Mendrisio to Florence costing on average $37 (€30).
Other travel options to Florence take longer:
Bus takes on average 7h 20m.
- Around 45 trains per day.
- Around 14 flights per day.
- Around 11 buses per day.
However, we recommend checking specific travel dates for your route between Mendrisio and Florence as scheduled services by train and bus can vary by season or day of the week.
- Flights mostly depart from Milan Malpensa Airport and arrive in Florence Peretola Airport.
- Trains mostly depart from Chiasso station and arrive in Florence Santa Maria Novella.
- Buses mostly depart from Como, Piazzale San Gottardo (Stazione San Giovanni) and arrive in Scandicci, Villa Costanza (Florence).
- Travel with Italo, Regionale, Swiss Federal Railways (SBB CFF FFS) to go to Florence by train.
Travelling from Mendrisio to Florence: related information
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