Travel Information
Compare train and bus for Mendrisio to Florence
Omio recommends booking the train as it is the most popular option from Mendrisio to Florence among Omio's users. If you are prioritising price take the train with prices starting from $24. For those with little time consider booking a train which can get you there in 4h 45m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.3kg. The ticket price range depends on the travel mode: a train costs an average of $24, and a train costs an average of $24.
Distance: 182 miles (294 km)
Compare train with
Most popular Train | Driving |
|---|---|
$31 Average price Cheapest | $80 Average price (fuel + tolls) |
5h 15m Average total duration Fastest 4h 45m Onboard + 30m Additional time* | 4h 6m Average total duration (door-to-door) |
0.1 - 0.3kg CO2 emissions Lowest | - CO2 emissions |
![]() Most popular train company | Your own car or car rental |
Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Mendrisio to Florence:
A train is $4 (€3) less than a bus for this route with tickets for a bus from Mendrisio to Florence costing on average $34 (€28).
Other travel options to Florence take longer:
Bus takes on average 6h 53m.
Compare prices and tickets Prices for trains, buses and flights
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FAQs: Travel from Mendrisio to Florence
Travel to Florence easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Mendrisio to Florence.

This is compared to other travel options from Mendrisio to Florence:
A train is $4 (€3) less than a bus for this route with tickets for a bus from Mendrisio to Florence costing on average $34 (€28).
Other travel options to Florence take longer:
Bus takes on average 6h 53m.
- Around 47 trains per day.
- Around 14 flights per day.
- Around 11 buses per day.
However, we recommend checking specific travel dates for your route between Mendrisio and Florence as scheduled services by train and bus can vary by season or day of the week.
- Trains mostly depart from Chiasso station and arrive in Florence Santa Maria Novella.
- Buses mostly depart from Como, Piazzale San Gottardo (Stazione San Giovanni) and arrive in Scandicci, Villa Costanza (Florence).
- Flights mostly depart from Milan Malpensa Airport and arrive in Florence Peretola Airport.
- Travel with Regionale, Intercity, Italo, Swiss Federal Railways (SBB CFF FFS) to go to Florence by train.
- 30 direct trains per day with Italo.
Travelling from Mendrisio to Florence: related information
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