Travel optionsfrom Mendrisio to Florence
How to get from Mendrisio to Florence by train, bus or flight.
Our recommendation
The best way to travel from Mendrisio to Florence is by taking a bus because it’s the best combination of price and speed.

Cheapest

Fastest

Find all the dates and times for this journey by train, bus, flight, and ferry .
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FAQs: Travel from Mendrisio to Florence
Travel to Florence easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Mendrisio to Florence.

- Around 45 trains per day.
- Around 14 flights per day.
- Around 11 buses per day.
However, we recommend checking specific travel dates for your route between Mendrisio and Florence as scheduled services by train, bus, and flight can vary by season or day of the week.
- Flights mostly depart from Milan Malpensa Airport and arrive in Florence Peretola Airport.
- Trains mostly depart from Chiasso station and arrive in Florence Santa Maria Novella.
- Buses mostly depart from Como, Piazzale San Gottardo (Stazione San Giovanni) and arrive in Scandicci, Villa Costanza (Florence).
- Travel with Italo, Regionale, Frecciarossa, Swiss Railways (SBB/CFF/FFS) to go to Florence by train.
- 28 direct trains per day with Italo.
Travelling from Mendrisio to Florence: related information
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