- Recommended
Cummer Museum of Art & Gardens
A nationally recognized museum featuring historic and modern art collections as well as a stunning garden.
Omio recommends booking the bus as it is the most popular option from Mechanicsburg, PA to Jacksonville, FL among Omio's users. If you are prioritising price take the bus with prices starting from $173. For those with little time consider booking a bus which can get you there in 30h 21m. The ticket price range depends on the travel mode: a bus costs an average of $173, and a bus costs an average of $173.
Distance: 731 miles (1177 km)
Most popular Bus | Driving |
|---|---|
$173 Average price Cheapest | $166 Average price (fuel + tolls) |
30h 51m Average total duration Fastest 30h 21m Onboard + 30m Additional time* | 12h 12m Average total duration (door-to-door) |
Direct Options | Direct Options |
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Rabbit Transit | Departure Time 11:19AM | Arrival Time 11:30AM | Duration 24h11 | Departure days Wed, Thu | Cheapest price $173 |
Operator Rabbit Transit | Departure Time 04:48PM | Arrival Time 11:30AM | Duration 42h42 | Departure days Sat | Cheapest price $173 |
The table below shows live departures for Mechanicsburg, PA to Jacksonville, FL buses for today, Saturday, May 16. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 4:48 PM Mechanicsburg, PA | 42h42 | 11:30 AM Jacksonville, FL | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
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Buses from Mechanicsburg, PA to Jacksonville, FL run on average 1 times per day, taking around 30h 21m. Cheap bus tickets for this journey start at $173 (€140) if you book in advance.
The earliest bus runs at 11:19, the last at 16:48. The fastest bus covers the 731 miles (1177 km) distance in 24h 11m.
Distance 731 miles (1177 km) |
Average bus duration 30h 21m |
Cheapest ticket price $173 (€140) |
Buses per day 1 |
Fastest bus 24h 11m |
First bus 11:19 AM |
Last bus 4:48 PM |
Discover the best of Jacksonville — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Jacksonville trip today.
A nationally recognized museum featuring historic and modern art collections as well as a stunning garden.
Focusing on local history, science, and innovation, this museum offers engaging exhibits and a planetarium.
Located in the historic African American community of LaVilla, it celebrates the heritage and culture of the area's residents.
A hip neighborhood known for its eclectic shops, dining, and vibrant nightlife.
A historic neighborhood with Mediterranean revival architecture, trendy eateries, and shopping.
A charming beach town offering stunning beach views, local eateries, and shops.
A popular Southern dish featuring shrimp cooked with a savory sauce and served over creamy grits, often seasoned with spices unique to Jacksonville.
Fresh shrimp caught from the nearby Mayport waters, often boiled or fried, showcasing local seafood quality.
A spicy condiment native to the region, made from the locally grown Datil Pepper. Adds a kick to many local meals.
A casual eatery known for its hearty breakfast and brunch offerings, including their famous biscuits and gravy.
A trendy spot known for its eclectic menu and modern American dishes, featuring a lively atmosphere and a creative cocktail menu.
Located in historic Avondale, this venue specializes in fresh seafood and a relaxed dining experience.
Jacksonville offers moderate prices compared to other major U.S. cities, with a variety of options for dining and accommodation.
15-20% is standard for restaurants. Round up at cafes and for taxi drivers. Tipping is customary for most services.
Find answers to the most common questions about traveling from Mechanicsburg, PA to Jacksonville, FL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Jacksonville, FL, this guide helps you travel smarter and with confidence.

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