- Must visit
The State Museum of Pennsylvania
Major regional museum with American art, natural history, and science exhibits. It is Harrisburg's best-known museum and a strong all-ages visit.
Buses from Cincinnati, OH to Harrisburg, PA run on average 4 times per day, taking around 12h 48m. Cheap bus tickets for this journey start at $58 if you book in advance.
There are 2 buses per day. The earliest bus runs at 01:41, the last at 21:05. The fastest bus covers the 413 miles (665 km) distance in 10h 35m.
Distance 413 miles (665 km) |
Average bus duration 12h 48m |
Cheapest ticket price $58 |
Buses per day 4 |
Direct buses 2 |
Fastest bus 10h 35m |
First bus 1:41 AM |
Last bus 9:05 PM |
Cheapest Month Aug |
Cheapest Day Sat |
High Season Jul - Sep |
Low Season Oct - Dec |
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Cincinnati, OH to Harrisburg, PA.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 04:40AM | Arrival Time 11:15PM | Duration 18h35 | Departure days Sun | Cheapest price $75 |
Operator Greyhound | Departure Time 08:25AM | Arrival Time 04:30AM | Duration 20h05 | Departure days Thu, Fri | Cheapest price $125 |
Operator Greyhound | Departure Time 09:25AM | Arrival Time 05:30AM | Duration 20h05 | Departure days Thu | Cheapest price $166 |
Operator FlixBus | Departure Time 02:10PM | Arrival Time 01:35AM | Duration 11h25 | Departure days Sun | Cheapest price $82 |
Operator FlixBus | Departure Time 03:00PM | Arrival Time 01:35AM | Duration 10h35 | Departure days Sun | Cheapest price $82 |
Operator Greyhound | Departure Time 05:40PM | Arrival Time 10:25AM | Duration 16h45 | Departure days Sun | Cheapest price $75 |
Operator Greyhound | Departure Time 10:30PM | Arrival Time 03:15PM | Duration 16h45 | Departure days Tue | Cheapest price $137 |
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
Discover the best of Harrisburg, PA — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Harrisburg, PA trip today.
Major regional museum with American art, natural history, and science exhibits. It is Harrisburg's best-known museum and a strong all-ages visit.
National Civil War museum with broad exhibits on soldiers, civilians, and the war's legacy. It is one of the city's most important history stops.
Museum at Fort Hunter highlighting local river history, mansion life, and the Susquehanna landscape. A quieter favorite with a scenic setting.
Riverfront promenade and park system with skyline views, paths, and event spaces. It is one of the most pleasant walks in central Harrisburg.
Car-free island in the Susquehanna with walking paths, recreation, and broad water views. A classic local escape close to downtown.
Victorian neighborhood known for colorful homes, local shops, and a creative atmosphere. It is ideal for strolling and seeing everyday Harrisburg charm.
Pennsylvania Dutch chicken pot pie is a rich stew with square noodles, chicken, and vegetables. It is a regional comfort food common around Harrisburg.
Shoofly pie is a classic Pennsylvania Dutch dessert made with molasses crumb filling. Its deep sweetness makes it a traditional local bakery staple.
Whoopie pie features two soft chocolate cake rounds with creamy filling. It is a beloved Amish and Pennsylvania Dutch treat found across the region.
Long-running local favorite serving creative American dishes and seafood in a comfortable, polished neighborhood setting.
Historic market with many established local vendors for Pennsylvania Dutch baked goods, pretzels, sandwiches, and regional specialties in a lively setting.
Popular casual tavern and brewery pouring local beer with pub fare. It is well known for a relaxed atmosphere and central location.
Moderate for US state capitals; hotels and dining are usually below major East Coast cities, while transit needs and limited cheap tourist areas can raise daily costs.
Tip 18-20% at restaurants, 15-20% for taxis, and $1-2 per drink or café order if service is provided.
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Harrisburg, PA.
Find answers to the most common questions about traveling from Cincinnati, OH to Harrisburg, PA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Harrisburg, PA, this guide helps you travel smarter and with confidence.

Most Cincinnati, OH to Harrisburg, PA buses use the Cincinnati, Greyhound Bus Station to Harrisburg, Market St (Bus Station) station pair, with some services arriving at Harrisburg, Chestnut Street / South 4th Street. Use this guide to compare Cincinnati, OH and Harrisburg, PA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Cincinnati, Greyhound Bus Station is 12 km from Cincinnati city centre. Public transport options include:
Cincinnati, Greyhound Bus Station has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Free Wi-Fi available in the waiting area. ATMs are aTM machines available inside the station.
Ticket office support is available at Cincinnati, Greyhound Bus Station.
Available at Cincinnati, Greyhound Bus Station: Parking, Taxis, WC.
Accessibility facilities are available at Cincinnati, Greyhound Bus Station: Wheelchair accessible entrances and seating available.
Cincinnati, Short Vine St (University of Cincinnati) is 3 km from Cincinnati city centre. Public transport options include:
Cincinnati, Short Vine St (University of Cincinnati) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Restaurants available along Short Vine St.
Wi-Fi is available at Cincinnati, Short Vine St (University of Cincinnati). ATMs are aTMs available in nearby banks.
Ticket office support is available at Cincinnati, Short Vine St (University of Cincinnati).
Available at Cincinnati, Short Vine St (University of Cincinnati): Parking, Taxis, WC.
Accessibility facilities are available at Cincinnati, Short Vine St (University of Cincinnati): Accessible pathways available.
Cincinnati, Gilbert Ave (Greyhound Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Cincinnati, Gilbert Ave (Greyhound Bus Station). ATMs are available at Cincinnati, Gilbert Ave (Greyhound Bus Station).
Ticket office support is available at Cincinnati, Gilbert Ave (Greyhound Bus Station).
Available at Cincinnati, Gilbert Ave (Greyhound Bus Station): Parking, Taxis, WC.
Accessibility facilities are available at Cincinnati, Gilbert Ave (Greyhound Bus Station): Wheelchair accessible facility.
Harrisburg, Market St (Bus Station) is 1 km from Harrisburg city centre. Public transport options include:
Harrisburg, Market St (Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Free WiFi inside the station. ATMs are available at Harrisburg, Market St (Bus Station).
Ticket office support is available at Harrisburg, Market St (Bus Station).
Available at Harrisburg, Market St (Bus Station): Parking, Taxis, WC.
Accessibility facilities are available at Harrisburg, Market St (Bus Station): Wheelchair accessible with ramps.
Harrisburg, Chestnut Street / South 4th Street is 1 km from Harrisburg city centre. Public transport options include:
Harrisburg, Chestnut Street / South 4th Street has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Harrisburg, Chestnut Street / South 4th Street. ATMs are available at Harrisburg, Chestnut Street / South 4th Street.
Ticket office support is available at Harrisburg, Chestnut Street / South 4th Street.
Available at Harrisburg, Chestnut Street / South 4th Street: Parking, Taxis, WC.
Accessibility facilities are available at Harrisburg, Chestnut Street / South 4th Street: Accessible by wheelchair via main entrance.
Check bus stations information for Cincinnati, OH and Harrisburg, PA, including where buses depart and arrive on this route.
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