Travel Information
Compare train, bus, and flight for Chicago, IL to Independence, MO
Omio recommends booking the train as it is the most popular option from Chicago, IL to Independence, MO among Omio's users. If you are prioritising price, take the train, with an average ticket price of €92 For those with little time, consider booking a flight, which has an average total journey time of 6h 43m. Average ticket prices depend on the travel mode: a train costs an average of €92, while a flight costs an average of €559.
Distance: 403 miles (649 km)
Compare bus with
| Bus | Most popular Train | Flight | Driving |
|---|---|---|---|
€103 Average price | €92 Average price Cheapest | €559 Average price | €84 Average price (fuel + tolls) |
13h 3m Average total duration 12h 33m Onboard + 30m Additional time* | 10h 36m Average total duration 10h 6m Onboard + 30m Additional time* | 6h 43m Average total duration Fastest 4h 43m Onboard + 2h 0m Additional time* | 7h 28m Average total duration (door-to-door) |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Chicago, IL to Independence, MO:
A train is €11 less than a bus for this route with tickets for a bus from Chicago, IL to Independence, MO costing on average €103.
A train is €467 less than a flight for this route with tickets for a flight from Chicago, IL to Independence, MO costing on average €559.
Other travel options to Independence, MO take longer:
Train takes on average 10h 6m.
Bus takes on average 12h 33m.
Tickets start at around €103 compared to roughly €84 in fuel and tolls — a saving of about €-19.32. The journey takes 12h 33m versus 7h 28m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
Chicago, IL to Independence, MO Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 07:45PM | Arrival Time 11:00AM | Duration 15h15 | Departure days Wed, Sat | Cheapest price €90 |
Operator FlixBus | Departure Time 10:15PM | Arrival Time 11:00AM | Duration 12h45 | Departure days Fri | Cheapest price €84 |
Live departures
Chicago, IL to Independence, MO bus times
The table below shows live departures for Chicago, IL to Independence, MO buses for today, Saturday, September 19. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 7:45 PM Chicago, IL | 15h15 | 11:00 AM Independence, MO | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Chicago, IL to Independence, MO by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Sep 20
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Journey information
Overview: Bus from Chicago, IL to Independence, MO
Buses from Chicago, IL to Independence, MO run on average 6 times per day, taking around 12h 33m. Cheap bus tickets for this journey start at €70 but you can travel from only €57 by train.
The earliest bus runs at 00:15, the last at 23:10. The fastest bus covers the 403 miles (649 km) distance in 10h 5m.
Distance 403 miles (649 km) |
Average bus duration 12h 33m |
Cheapest ticket price €70 |
Buses per day 6 |
Fastest bus 10h 5m |
First bus 12:15 AM |
Last bus 11:10 PM |
Cheapest Month Jan |
Cheapest Day Sun |
High Season Apr - Jun |
Low Season Oct - Dec |
FAQs: Bus from Chicago, IL to Independence, MO
Find answers to the most common questions about traveling from Chicago, IL to Independence, MO by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Independence, MO, this guide helps you travel smarter and with confidence.

popular bus stations
Popular bus stations from Chicago, IL to Independence, MO
Most Chicago, IL to Independence, MO buses use the Chicago, Greyhound Bus Station to Kansas City, Jefferson Lines station pair. Use this guide to compare Chicago, IL and Independence, MO bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Which Chicago, IL station do buses to Independence, MO leave from?
Getting to Chicago, Greyhound Bus Station from Chicago city centre
Chicago, Greyhound Bus Station is 2 km from Chicago city centre. Public transport options include:
Chicago, Greyhound Bus Station bus station facilities and services
Chicago, Greyhound Bus Station has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Snack shop and vending machines available
Wi-Fi and ATMs
Free Wi-Fi in waiting area. ATMs are located near entrance.
Tickets and information
Ticket office support is available at Chicago, Greyhound Bus Station.
Parking, taxis and toilets
Available at Chicago, Greyhound Bus Station: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Chicago, Greyhound Bus Station: Wheelchair accessible entrances and seating.
Getting to Chicago, Union Station (Amtrak) from Chicago city centre
Chicago, Union Station (Amtrak) is 3 km from Chicago city centre. Public transport options include:
Chicago, Union Station (Amtrak) bus station facilities and services
Chicago, Union Station (Amtrak) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Multiple dining options are available inside the station.
Wi-Fi and ATMs
Free Wi-Fi is available in waiting areas. ATMs are aTMs are located near the main entrance.
Tickets and information
Ticket office support is available at Chicago, Union Station (Amtrak).
Parking, taxis and toilets
Available at Chicago, Union Station (Amtrak): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Chicago, Union Station (Amtrak): Station is accessible with elevators and ramps.
Most popular bus connections from Chicago, IL
More options for your journey from Chicago, IL to Independence, MO
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