Travel Information
Compare train, bus, and flight for Chicago, IL to Independence, MO
Omio recommends booking the train as it is the most popular option from Chicago, IL to Independence, MO among Omio's users. If you are prioritising price take the bus with prices starting from $60. For those with little time consider booking a flight which can get you there in 1h 44m. The ticket price range depends on the travel mode: a bus costs an average of $60, and a flight costs an average of $404.
Distance: 403 miles (649 km)
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
$72 Average price Cheapest | $82 Average price | $404 Average price |
20h 43m Average total duration 20h 13m Onboard + 30m Additional time* | 10h 33m Average total duration 10h 3m Onboard + 30m Additional time* | 4h 44m Average total duration Fastest 1h 44m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
Compare prices and tickets Chicago, IL to Independence, MO by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Bus from Chicago, IL to Independence, MO
Buses from Chicago, IL to Independence, MO run on average 5 times per day, taking around 20h 13m. Cheap bus tickets for this journey start at $60 (€49) but you can travel from only $59 (€48) by train.
The earliest bus runs at 00:15, the last at 23:50. The fastest bus covers the 403 miles (649 km) distance in 20h 0m.
Distance 403 miles (649 km) |
Average bus duration 20h 13m |
Cheapest ticket price $60 (€49) |
Buses per day 5 |
Fastest bus 20h 0m |
First bus 00:15 |
Last bus 23:50 |
Cheapest month May |
Cheapest day Mon |
High season Apr - Jun |
Low season Oct - Dec |
FAQs: Bus from Chicago, IL to Independence, MO
Find answers to the most common questions about traveling from Chicago, IL to Independence, MO by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Independence, MO, this guide helps you travel smarter and with confidence.

popular bus stations
Popular bus stations from Chicago, IL to Independence, MO
Most popular bus connections from Chicago, IL
More options for your journey from Chicago, IL to Independence, MO
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