Travel optionsfrom Frankfurt am Main to Sint-Gillis
How to get from Frankfurt am Main to Sint-Gillis by train, bus or flight.
Our recommendation
The best way to travel from Frankfurt am Main to Sint-Gillis is by taking a bus because it’s the best combination of price and speed.
(Prague -> Amsterdam)+
521205:25 AM14h00Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof)7:25 PMBrussels, Brussels South (Gare du Midi)$321One-way1 transfer
Cheapest
(Prague -> Amsterdam)+
521205:25 AM14h00Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof)7:25 PMBrussels, Brussels South (Gare du Midi)$321One-way1 transfer
Fastest
SN26144:25 PM1h05Frankfurt am Main Airport5:30 PMBrussels Airport$5071One-way0 transfers
Other options
29532 · Bus 82159 · Bus 5943 · IC 21277:24 PM12h04Frankfurt (Main) Hbf7:28 AMBrussels-Midi$1081One-way3 transfers
ICE 622 · 10928 · S41 · IC 5456:08 PM6h21Frankfurt (Main) Hbf12:29 AMBrussels-Midi$1121One-way3 transfers
29542 · IC 2041 · ICE 104:24 PM5h11Frankfurt (Main) Hbf9:35 PMBrussels-Midi$1241One-way2 transfers
(Prague -> Amsterdam)+
504295:25 AM10h15Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof)3:40 PMBrussels, Brussels South (Gare du Midi)$341One-way1 transfer
LH914+
SN20964:00 PM4h00Frankfurt am Main Airport8:00 PMBrussels Airport$3311One-way1 transfer
LH1394+
SN28109:50 AM3h30Frankfurt am Main Airport1:20 PMBrussels Airport$3951One-way1 transfer
KL1818 · KL170511:45 AM2h55Frankfurt am Main Airport2:40 PMBrussels Airport$4141One-way1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
Travel Information
Compare bus, train, and flight for Frankfurt am Main to Sint-Gillis
Omio recommends booking the train as it is the most popular option from Frankfurt am Main to Sint-Gillis among Omio's users. If you are prioritising price take the train with prices starting from $53. For those with little time consider booking a train which can get you there in 3h 20m. The ticket price range depends on the travel mode: a train costs an average of $53, and a train costs an average of $53.
Distance: 196 miles (317 km)
Compare train with
Most popular Train | Driving |
|---|---|
$157 Average price Cheapest | $82 Average price (fuel + tolls) |
3h 50m Average total duration Fastest 3h 20m Onboard + 30m Additional time* | 4h 40m Average total duration (door-to-door) |
![]() Most popular train company | Your own car or car rental |
Direct Options | Direct Options |
This is compared to other travel options from Frankfurt am Main to Sint-Gillis:
A bus is $110 less than a train for this route with tickets for a train from Frankfurt am Main to Sint-Gillis costing on average $157.
A bus is $357 less than a flight for this route with tickets for a flight from Frankfurt am Main to Sint-Gillis costing on average $404.
Other travel options to Sint-Gillis take longer:
Flight takes on average 6h 35m.
Bus takes on average 6h 55m.
Compare prices and tickets Prices for trains, buses and flights
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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FAQs: Travel from Frankfurt am Main to Sint-Gillis
Travel to Sint-Gillis easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Frankfurt am Main to Sint-Gillis.

This is compared to other travel options from Frankfurt am Main to Sint-Gillis:
A bus is $110 less than a train for this route with tickets for a train from Frankfurt am Main to Sint-Gillis costing on average $157.
A bus is $357 less than a flight for this route with tickets for a flight from Frankfurt am Main to Sint-Gillis costing on average $404.
Other travel options to Sint-Gillis take longer:
Flight takes on average 6h 35m.
Bus takes on average 6h 55m.
- Around 30 flights per day.
- Around 18 buses per day.
- Around 4 trains per day.
However, we recommend checking specific travel dates for your route between Frankfurt am Main and Sint-Gillis as scheduled services by bus, train, and flight can vary by season or day of the week.
- Trains mostly depart from Frankfurt (Main) Hbf and arrive in Brussels-Midi.
- Flights mostly depart from Frankfurt am Main Airport and arrive in Brussels Airport.
- Buses mostly depart from Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) and arrive in Brussels, Brussels South (Gare du Midi).
- Travel with Trans Nicolaescu to go to Sint-Gillis by bus.
- Travel with Deutsche Bahn, Deutsche Bahn Intercity (DB IC) to go to Sint-Gillis by train.
- 2 direct trains per day with Deutsche Bahn.
Travelling from Frankfurt am Main to Sint-Gillis: related information
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