Travel Information
Compare train and bus for Domodossola to Milan
Omio recommends booking the train as it is the most popular option from Domodossola to Milan among Omio's users. If you are prioritising price, take the bus, with an average ticket price of Kč303 For those with little time, consider booking a train, which has an average total journey time of 2h 25m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.0 - 0.1kg. Average ticket prices depend on the travel mode: a bus costs an average of Kč303, while a train costs an average of Kč305.
Distance: 62 miles (100 km)
Compare train with
Most popular Train | Bus | Driving |
|---|---|---|
Kč305 Average price | Kč303 Average price Cheapest | Kč973 Average price (fuel + tolls) |
2h 25m Average total duration Fastest 1h 55m Onboard + 30m Additional time* | 2h 36m Average total duration 2h 6m Onboard + 30m Additional time* | 1h 42m Average total duration (door-to-door) |
0.0 - 0.1kg CO2 emissions Lowest | 0.1 - 0.3kg CO2 emissions | - CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Domodossola to Milan:
A bus is Kč2 less than a train for this route with tickets for a train from Domodossola to Milan costing on average Kč305.
Other travel options to Milan take longer:
Bus takes on average 2h 36m.
Tickets start at around Kč305 compared to roughly Kč973 in fuel and tolls — a saving of about Kč668. The journey takes 1h 55m versus 1h 42m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
Travel optionsfrom Domodossola to Milan
How to get from Domodossola to Milan by train, bus or flight.
Our recommendation
The best way to travel from Domodossola to Milan is by taking a bus because it’s the best combination of price and speed.
Autobus TRENORD 2427A · Regionale TRENORD 242712:10 PM2h25Domodossola station2:35 PMMilan CentraleKč2881One-way1 transfer
Cheapest
Autobus TRENORD 2427A · Regionale TRENORD 242712:10 PM2h25Domodossola station2:35 PMMilan CentraleKč2881One-way1 transfer
Fastest
Autobus EC0454:30 PM2h20Domodossola station6:50 PMMilan CentraleKč4141One-way0 transfers
Other options
Regionale 11415 · Regionale Veloce 20156:17 AM2h28Domodossola station8:45 AMMilan CentraleKč3061One-way1 transfer
Regionale 11433 · S6 TRENORD 246933:45 PM2h44Domodossola station6:29 PMMilano CertosaKč3061One-way1 transfer
Regionale 11413 · Regionale Veloce 20535:20 AM2h55Domodossola station8:15 AMMilan Porta GaribaldiKč3061One-way1 transfer
Autobus TRENORD 4419A · Regionale TRENORD 24198:03 AM2h32Domodossola station10:35 AMMilan CentraleKč2881One-way1 transfer
Autobus TRENORD 4439A · Regionale TRENORD 24396:03 PM2h32Domodossola station8:35 PMMilan CentraleKč2881One-way1 transfer
Autobus TRENORD 4437A · Regionale TRENORD 24375:03 PM2h32Domodossola station7:35 PMMilan CentraleKč2881One-way1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
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FAQs: Travel from Domodossola to Milan
Travel to Milan easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Domodossola to Milan.

This is compared to other travel options from Domodossola to Milan:
A bus is Kč2 less than a train for this route with tickets for a train from Domodossola to Milan costing on average Kč305.
Other travel options to Milan take longer:
Bus takes on average 2h 36m.
- Around 18 trains per day.
- Around 11 buses per day.
However, we recommend checking specific travel dates for your route between Domodossola and Milan as scheduled services by train and bus can vary by season or day of the week.
- Trains mostly depart from Domodossola station and arrive in Milan Centrale.
- Travel with Regionale, Trenord to go to Milan by train.
- Travel with BlaBlaCar, Autoservizi Comazzi srl to go to Milan by bus.
- 8 direct trains per day with Regionale, Trenord.
- 4 direct buses per day with BlaBlaCar.
Travelling from Domodossola to Milan: related information
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