Travel Information
Compare train and bus for Brno to Karlovy Vary
Omio recommends booking the bus as it is the most popular option from Brno to Karlovy Vary among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $18 For those with little time, consider booking a bus, which has an average total journey time of 5h 25m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.1 - 0.3kg. Average ticket prices depend on the travel mode: a bus costs an average of $18, while a train costs an average of $29.
Distance: 181 miles (292 km)
Compare bus with
Most popular Bus | Train | Driving |
|---|---|---|
$18 Average price Cheapest | $29 Average price | $79 Average price (fuel + tolls) |
5h 25m Average total duration Fastest 4h 55m Onboard + 30m Additional time* | 5h 56m Average total duration 5h 26m Onboard + 30m Additional time* | 3h 30m Average total duration (door-to-door) |
0.3 - 0.7kg CO2 emissions | 0.1 - 0.3kg CO2 emissions Lowest | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Brno to Karlovy Vary:
A bus is $11 less than a train for this route with tickets for a train from Brno to Karlovy Vary costing on average $29.
Other travel options to Karlovy Vary take longer:
Train takes on average 5h 56m.
Tickets start at around $18 compared to roughly $79 in fuel and tolls — a saving of about $60. The journey takes 4h 55m versus 3h 30m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
Travel optionsfrom Brno to Karlovy Vary
How to get from Brno to Karlovy Vary by train, bus or flight.
Our recommendation
The best way to travel from Brno to Karlovy Vary is by taking a bus because it’s the best combination of price and speed.
FlixBus12:10 PM4h50Brno, Benešova - Grandhotel (Hlavní nádraží)5:00 PMKarlovy Vary, Dolní Nádraží$151One-way0 transfers
Cheapest
FlixBus12:10 PM4h50Brno, Benešova - Grandhotel (Hlavní nádraží)5:00 PMKarlovy Vary, Dolní Nádraží$151One-way0 transfers
Fastest
FlixBus · FlixBus1:10 PM4h45Brno, Benešova - Grandhotel (Hlavní nádraží)5:55 PMKarlovy Vary, Tržnice$381One-way1 transfer
Other options
RJ 256 · R 6128:46 AM6h15Brno hlavní nádraží3:01 PMKarlovy Vary, nádraží$1331One-way1 transfer
RJ 254 · R 61010:46 AM6h15Brno hlavní nádraží5:01 PMKarlovy Vary, nádraží$1331One-way1 transfer
RJ 252 · R 60812:46 PM6h15Brno hlavní nádraží7:01 PMKarlovy Vary, nádraží$1331One-way1 transfer
FlixBus1:10 PM6h15Brno, Benešova - Grandhotel (Hlavní nádraží)7:25 PMKarlovy Vary, Tržnice$151One-way0 transfers
FlixBus1:10 PM6h20Brno, Benešova - Grandhotel (Hlavní nádraží)7:30 PMKarlovy Vary, Dolní Nádraží$151One-way0 transfers
(Brno -> Prague) · (Prague -> Karlovy Vary)5:30 AM6h15Brno, Benešova - Grandhotel (Hlavní nádraží)11:45 AMKarlovy Vary, Dolní Nádraží$211One-way1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
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Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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FAQs: Travel from Brno to Karlovy Vary
Travel to Karlovy Vary easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Brno to Karlovy Vary.

This is compared to other travel options from Brno to Karlovy Vary:
A bus is $9 less than a train for this route with tickets for a train from Brno to Karlovy Vary costing on average $34.
Other travel options to Karlovy Vary take longer:
Train takes on average 6h 38m.
- Around 15 buses per day.
- Around 6 trains per day.
However, we recommend checking specific travel dates for your route between Brno and Karlovy Vary as scheduled services by train and bus can vary by season or day of the week.
- Trains mostly depart from Brno hlavní nádraží and arrive in Karlovy Vary, nádraží.
- Buses mostly depart from Brno, Benešova - Grandhotel (Hlavní nádraží) and arrive in Karlovy Vary, Dolní Nádraží.
- Travel with FlixBus to go to Karlovy Vary by bus.
- Travel with České dráhy to go to Karlovy Vary by train.
- 3 direct buses per day with FlixBus.
Travelling from Brno to Karlovy Vary: related information
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