Travel Information
Compare train and bus for Brno to Karlovy Vary
Omio recommends booking the bus as it is the most popular option from Brno to Karlovy Vary among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $25 For those with little time, consider booking a bus, which has an average total journey time of 5h 22m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.1 - 0.3kg. Average ticket prices depend on the travel mode: a bus costs an average of $25, while a train costs an average of $48.
Distance: 181 miles (292 km)
Compare bus with
Most popular Bus | Train | Driving |
|---|---|---|
$25 Average price Cheapest | $48 Average price | $77 Average price (fuel + tolls) |
5h 22m Average total duration Fastest 4h 52m Onboard + 30m Additional time* | 6h 38m Average total duration 6h 8m Onboard + 30m Additional time* | 3h 30m Average total duration (door-to-door) |
0.3 - 0.7kg CO2 emissions | 0.1 - 0.3kg CO2 emissions Lowest | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Compare ways to travel from Brno to Karlovy Vary
Compare the available ways to get from Brno to Karlovy Vary, with the key details around price, speed, convenience, and direct service.
This is compared to other travel options from Brno to Karlovy Vary:
A bus is $23 (€20) less than a train for this route with tickets for a train from Brno to Karlovy Vary costing on average $48 (€41).
Other travel options to Karlovy Vary take longer:
Train takes on average 6h 38m.
Tickets start at around $25 (€21) compared to roughly $77 (€65) in fuel and tolls — a saving of about $52 (€44). The journey takes 4h 52m versus 3h 30m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
Travel optionsfrom Brno to Karlovy Vary
How to get from Brno to Karlovy Vary by train, bus or flight.
Our recommendation
The best way to travel from Brno to Karlovy Vary is by taking a bus because it’s the best combination of price and speed.
FlixBus · FlixBus1:10 PM 4h45 Brno, Benešova - Grandhotel (Hlavní nádraží) 5:55 PM Karlovy Vary, Tržnice $15 1 One-way 1 transfer
Cheapest
FlixBus · FlixBus1:10 PM 4h45 Brno, Benešova - Grandhotel (Hlavní nádraží) 5:55 PM Karlovy Vary, Tržnice $15 1 One-way 1 transfer
Fastest
FlixBus · FlixBus1:10 PM 4h45 Brno, Benešova - Grandhotel (Hlavní nádraží) 5:55 PM Karlovy Vary, Tržnice $15 1 One-way 1 transfer
Other options
rj 174 · Sp 1948 · Os 706211:46 AM 6h20 Brno hlavní nádraží 6:06 PM Karlovy Vary, nádraží $26 1 One-way 2 transfers
EC 280 · rj 176 · Sp 1946 · Os 70609:46 AM 6h20 Brno hlavní nádraží 4:06 PM Karlovy Vary, nádraží $30 1 One-way 3 transfers
rj 256 · R 6128:46 AM 6h15 Brno hlavní nádraží 3:01 PM Karlovy Vary, nádraží $31 1 One-way 1 transfer
FlixBus · FlixBus1:10 PM 4h50 Brno, Benešova - Grandhotel (Hlavní nádraží) 6:00 PM Karlovy Vary, Dolní Nádraží $15 1 One-way 1 transfer
FlixBus · FlixBus7:40 AM 5h15 Brno, Benešova - Grandhotel (Hlavní nádraží) 12:55 PM Karlovy Vary, Tržnice $15 1 One-way 1 transfer
FlixBus · FlixBus7:40 AM 5h20 Brno, Benešova - Grandhotel (Hlavní nádraží) 1:00 PM Karlovy Vary, Dolní Nádraží $15 1 One-way 1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
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FAQs: Travel from Brno to Karlovy Vary
Travel to Karlovy Vary easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Brno to Karlovy Vary.

This is compared to other travel options from Brno to Karlovy Vary:
A bus is $23 (€20) less than a train for this route with tickets for a train from Brno to Karlovy Vary costing on average $48 (€41).
Other travel options to Karlovy Vary take longer:
Train takes on average 6h 38m.
- Around 15 buses per day.
- Around 5 trains per day.
However, we recommend checking specific travel dates for your route between Brno and Karlovy Vary as scheduled services by train and bus can vary by season or day of the week.
- Trains mostly depart from Brno hlavní nádraží and arrive in Karlovy Vary, nádraží.
- Buses mostly depart from Brno, Benešova - Grandhotel (Hlavní nádraží) and arrive in Karlovy Vary, Dolní Nádraží.
- Travel with FlixBus to go to Karlovy Vary by bus.
- Travel with České dráhy, Deutsche Bahn to go to Karlovy Vary by train.
- 3 direct buses per day with FlixBus.
Travelling from Brno to Karlovy Vary: related information
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