Travel optionsfrom Frankfurt am Main to Karlovy Vary
How to get from Frankfurt am Main to Karlovy Vary by train, bus or flight.
Our recommendation
The best way to travel from Frankfurt am Main to Karlovy Vary is by taking a bus because it’s the best combination of price and speed.
FlixBus9:00 AM6h55Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof)3:55 PMKarlovy Vary, Dolní Nádraží$431One-way0 transfers
Cheapest
FlixBus9:00 AM6h55Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof)3:55 PMKarlovy Vary, Dolní Nádraží$431One-way0 transfers
Fastest
DE44073:00 PM1h00Frankfurt am Main Airport4:00 PMPrague Vaclav Havel Airport$1781One-way0 transfers
Other options
R 4609 · R 3007 · R 20881 · Sp 16689:36 AM7h55Frankfurt South station5:31 PMKarlovy Vary, nádraží$1691One-way3 transfers
ICE 25 · R 4609 · R 3007 · R 2088110:02 AM7h29Frankfurt Airport long-distance station5:31 PMKarlovy Vary, nádraží$1991One-way4 transfers
ICE 23 · R 4605 · R 3005 · R 208798:02 AM7h29Frankfurt Airport long-distance station3:31 PMKarlovy Vary, nádraží$1991One-way4 transfers
(Amsterdam -> Prague) · (Prague -> Karlovy Vary)10:30 PM11h15Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof)9:45 AMKarlovy Vary, Dolní Nádraží$601One-way1 transfer
FlixBus · FlixBus10:40 AM14h20Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36)1:00 AMKarlovy Vary, Dolní Nádraží$651One-way1 transfer
FlixBus · FlixBus4:20 AM11h35Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36)3:55 PMKarlovy Vary, Dolní Nádraží$721One-way1 transfer
DE44118:25 PM1h00Frankfurt am Main Airport9:25 PMPrague Vaclav Havel Airport$1781One-way0 transfers
DE440910:00 AM1h00Frankfurt am Main Airport11:00 AMPrague Vaclav Havel Airport$1781One-way0 transfers
LO382 · LO52110:35 AM6h45Frankfurt am Main Airport5:20 PMPrague Vaclav Havel Airport$3261One-way1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
Travel Information
Compare bus, train, and flight for Frankfurt am Main to Karlovy Vary
Omio recommends booking the train as it is the most popular option from Frankfurt am Main to Karlovy Vary among Omio's users. If you are prioritising price take the bus with prices starting from $25. For those with little time consider booking a train which can get you there in 4h 55m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.3kg. The ticket price range depends on the travel mode: a bus costs an average of $25, and a train costs an average of $33.
Distance: 185 miles (298 km)
Compare train with
Most popular Train | Bus | Driving |
|---|---|---|
$48 Average price | $41 Average price Cheapest | $70 Average price (fuel + tolls) |
5h 25m Average total duration Fastest 4h 55m Onboard + 30m Additional time* | 8h 22m Average total duration 7h 52m Onboard + 30m Additional time* | 4h 21m Average total duration (door-to-door) |
0.1 - 0.3kg CO2 emissions Lowest | 0.3 - 0.7kg CO2 emissions | - CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Frankfurt am Main to Karlovy Vary:
A bus is $7 less than a train for this route with tickets for a train from Frankfurt am Main to Karlovy Vary costing on average $48.
A bus is $167 less than a flight for this route with tickets for a flight from Frankfurt am Main to Karlovy Vary costing on average $208.
Other travel options to Karlovy Vary take longer:
Train takes on average 4h 55m.
Bus takes on average 7h 52m.
Compare prices and tickets Prices for trains, buses and flights
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Aug 06
Aug 07
Aug 08
Aug 09
Aug 10
Aug 11
Aug 12
More than 1,000 travel companies trust us to sell their tickets all in one place.
FAQs: Travel from Frankfurt am Main to Karlovy Vary
Travel to Karlovy Vary easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Frankfurt am Main to Karlovy Vary.

This is compared to other travel options from Frankfurt am Main to Karlovy Vary:
A bus is $7 less than a train for this route with tickets for a train from Frankfurt am Main to Karlovy Vary costing on average $48.
A bus is $167 less than a flight for this route with tickets for a flight from Frankfurt am Main to Karlovy Vary costing on average $208.
Other travel options to Karlovy Vary take longer:
Train takes on average 4h 55m.
Bus takes on average 7h 52m.
- Around 46 flights per day.
- Around 15 trains per day.
- Around 6 buses per day.
However, we recommend checking specific travel dates for your route between Frankfurt am Main and Karlovy Vary as scheduled services by bus, train, and flight can vary by season or day of the week.
- Flights mostly depart from Frankfurt am Main Airport and arrive in Prague Vaclav Havel Airport.
- Trains mostly depart from Frankfurt (Main) Hbf and arrive in Karlovy Vary, nádraží.
- Buses mostly depart from Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) and arrive in Karlovy Vary, Dolní Nádraží.
- Travel with FlixBus to go to Karlovy Vary by bus.
- Travel with Deutsche Bahn, České dráhy, Deutsche Bahn Intercity (DB IC), Deutsche Bahn Regio (DB Regional) to go to Karlovy Vary by train.
- 1 direct buses per day with FlixBus.
Travelling from Frankfurt am Main to Karlovy Vary: related information
Here are some other resources that might have the information you need

