Travel Information
Compare bus, train, and flight for Frankfurt am Main to Karlovy Vary
Omio recommends booking the bus as it is the most popular option from Frankfurt am Main to Karlovy Vary among Omio's users. If you are prioritising price, take the bus, with an average ticket price of €47 For those with little time, consider booking a flight, which has an average total journey time of 4h 45m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.1 - 0.3kg. Average ticket prices depend on the travel mode: a bus costs an average of €47, while a flight costs an average of €351.
Distance: 185 miles (298 km)
Compare bus with
Most popular Bus | Train | Flight | Driving |
|---|---|---|---|
€47 Average price Cheapest | €85 Average price | €351 Average price | €58 Average price (fuel + tolls) |
9h 23m Average total duration 8h 53m Onboard + 30m Additional time* | 6h 22m Average total duration 5h 52m Onboard + 30m Additional time* | 4h 45m Average total duration Fastest 2h 45m Onboard + 2h 0m Additional time* | 4h 21m Average total duration (door-to-door) |
0.3 - 0.7kg CO2 emissions | 0.1 - 0.3kg CO2 emissions Lowest | - CO2 emissions | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Compare ways to travel from Frankfurt am Main to Karlovy Vary
Compare the available ways to get from Frankfurt am Main to Karlovy Vary, with the key details around price, speed, convenience, and direct service.
This is compared to other travel options from Frankfurt am Main to Karlovy Vary:
A bus is €38 less than a train for this route with tickets for a train from Frankfurt am Main to Karlovy Vary costing on average €85.
A bus is €305 less than a flight for this route with tickets for a flight from Frankfurt am Main to Karlovy Vary costing on average €351.
Other travel options to Karlovy Vary take longer:
Train takes on average 6h 22m.
Bus takes on average 9h 23m.
Tickets start at around €47 compared to roughly €58 in fuel and tolls — a saving of about €12. The journey takes 8h 53m versus 4h 21m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
Travel optionsfrom Frankfurt am Main to Karlovy Vary
How to get from Frankfurt am Main to Karlovy Vary by train, bus or flight.
Our recommendation
The best way to travel from Frankfurt am Main to Karlovy Vary is by taking a train because it’s the best combination of price and speed.
ICE 621 · R 3469 · OPB 79726 · Sp 528910:57 AM 6h34 Frankfurt (Main) Hbf 5:31 PM Karlovy Vary, nádraží €28 1 One-way 4 transfers
Cheapest
ICE 621 · R 3469 · OPB 79726 · Sp 528910:57 AM 6h34 Frankfurt (Main) Hbf 5:31 PM Karlovy Vary, nádraží €28 1 One-way 4 transfers
Fastest
DE44842:30 PM 1h00 Frankfurt am Main Airport 3:30 PM Prague Vaclav Havel Airport €138 1 One-way 0 transfers
Other options
ICE 523 · 3461 · 5285 · Sp 16646:57 AM 6h34 Frankfurt (Main) Hbf 1:31 PM Karlovy Vary, nádraží €33 1 One-way 4 transfers
ICE 523 · 3461 · 5285 · Sp 16646:41 AM 6h50 Frankfurt Airport long-distance station 1:31 PM Karlovy Vary, nádraží €33 1 One-way 4 transfers
ICE 521 · 3459 · 4854 · R 6135:54 AM 7h01 Frankfurt (Main) Hbf 12:55 PM Karlovy Vary, nádraží €33 1 One-way 4 transfers
FlixBus · FlixBus11:59 PM 11h06 Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) 11:05 AM Karlovy Vary, Tržnice €40 1 One-way 1 transfer
FlixBus · FlixBus11:59 PM 11h11 Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) 11:10 AM Karlovy Vary, Dolní Nádraží €40 1 One-way 1 transfer
FlixBus · FlixBus11:30 PM 11h35 Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) 11:05 AM Karlovy Vary, Tržnice €41 1 One-way 1 transfer
DE44829:55 AM 1h00 Frankfurt am Main Airport 10:55 AM Prague Vaclav Havel Airport €138 1 One-way 0 transfers
DE44808:10 PM 1h00 Frankfurt am Main Airport 9:10 PM Prague Vaclav Havel Airport €174 1 One-way 0 transfers
LO378 · LO5294:55 PM 4h50 Frankfurt am Main Airport 9:45 PM Prague Vaclav Havel Airport €271 1 One-way 1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
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FAQs: Travel from Frankfurt am Main to Karlovy Vary
Travel to Karlovy Vary easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Frankfurt am Main to Karlovy Vary.

This is compared to other travel options from Frankfurt am Main to Karlovy Vary:
A bus is €38 less than a train for this route with tickets for a train from Frankfurt am Main to Karlovy Vary costing on average €85.
A bus is €305 less than a flight for this route with tickets for a flight from Frankfurt am Main to Karlovy Vary costing on average €351.
Other travel options to Karlovy Vary take longer:
Train takes on average 6h 22m.
Bus takes on average 9h 23m.
- Around 51 flights per day.
- Around 9 trains per day.
- Around 5 buses per day.
However, we recommend checking specific travel dates for your route between Frankfurt am Main and Karlovy Vary as scheduled services by bus, train, and flight can vary by season or day of the week.
- Flights mostly depart from Frankfurt am Main Airport and arrive in Prague Vaclav Havel Airport.
- Trains mostly depart from Frankfurt (Main) Hbf and arrive in Karlovy Vary, nádraží.
- Buses mostly depart from Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) and arrive in Karlovy Vary, Dolní Nádraží.
- Travel with FlixBus to go to Karlovy Vary by bus.
- Travel with Deutsche Bahn, České dráhy to go to Karlovy Vary by train.
- Travel with Lufthansa, KLM, Lot Polish Airlines, Condor Flugdienst, British Airways, Austrian Airlines, Turkish Airlines, Qatar Airways, KLM Cityhopper, Swiss, Air Baltic, Air Dolomiti, Brussels Airlines, Lufthansa Cityline, CitizenPlane, Helvetic Airways, Edelweiss Air to go to Karlovy Vary by flight.
- 1 direct buses per day with FlixBus.
- 8 direct flights per day with Lufthansa, Condor Flugdienst, Air Dolomiti.
Travelling from Frankfurt am Main to Karlovy Vary: related information
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