Travel Information
Compare bus, train, and flight for Frankfurt am Main to Karlovy Vary
Omio recommends booking the train as it is the most popular option from Frankfurt am Main to Karlovy Vary among Omio's users. If you are prioritising price take the train with prices starting from €23. For those with little time consider booking a train which can get you there in 4h 55m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.3kg. The ticket price range depends on the travel mode: a train costs an average of €23, and a bus costs an average of €22.
Distance: 185 miles (298 km)
Compare train with
Most popular Train | Bus |
|---|---|
€39 Average price Cheapest | €39 Average price |
5h 25m Average total duration Fastest 4h 55m Onboard + 30m Additional time* | 8h 20m Average total duration 7h 50m Onboard + 30m Additional time* |
0.1 - 0.3kg CO2 emissions Lowest | 0.3 - 0.7kg CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company |
Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Travel optionsfrom Frankfurt am Main to Karlovy Vary
How to get from Frankfurt am Main to Karlovy Vary by train, bus or flight.
Our recommendation
The best way to travel from Frankfurt am Main to Karlovy Vary is by taking a bus because it’s the best combination of price and speed.
FlixBusCheapest
ICE 527 · R 3465 · Sp 5287 · Os 7007Fastest
DE4409Other options
ICE 1557 · rj 383 · R 608
ICE 527 · 3465 · Bus EV · Os 7007
ICE 527 · 3465 · Bus EV · Os 7007
FlixBus · FlixBus
FlixBus · FlixBus
(Amsterdam -> Prague) · (Prague -> Karlovy Vary)
DE4411
DE4407
LO384 · LO527Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
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FAQs: Travel from Frankfurt am Main to Karlovy Vary
Travel to Karlovy Vary easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Frankfurt am Main to Karlovy Vary.

This is compared to other travel options from Frankfurt am Main to Karlovy Vary:
A bus is $0.77 (€0.61) less than a train for this route with tickets for a train from Frankfurt am Main to Karlovy Vary costing on average $29 (€23).
A bus is $137 (€109) less than a flight for this route with tickets for a flight from Frankfurt am Main to Karlovy Vary costing on average $165 (€132).
Other travel options to Karlovy Vary take longer:
Train takes on average 5h 2m.
Bus takes on average 6h 55m.
- Around 43 flights per day.
- Around 14 trains per day.
- Around 6 buses per day.
However, we recommend checking specific travel dates for your route between Frankfurt am Main and Karlovy Vary as scheduled services by bus, train, and flight can vary by season or day of the week.
- Flights mostly depart from Frankfurt am Main Airport and arrive in Prague Vaclav Havel Airport.
- Trains mostly depart from Frankfurt (Main) Hbf and arrive in Karlovy Vary, nádraží.
- Buses mostly depart from Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) and arrive in Karlovy Vary, Dolní Nádraží.
- Travel with FlixBus to go to Karlovy Vary by bus.
- Travel with Deutsche Bahn to go to Karlovy Vary by train.
- 1 direct buses per day with FlixBus.
Travelling from Frankfurt am Main to Karlovy Vary: related information
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