- Must visit
Vatican Museums
World-famous papal museums with the Sistine Chapel, Raphael Rooms, and major classical collections.
Omio recommends booking the flight as it is the most popular option from Strasbourg to Rome among Omio's users. If you are prioritising price take the bus with prices starting from $72. For those with little time consider booking a flight which can get you there in 2h 23m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 0.8 - 2.1kg. The ticket price range depends on the travel mode: a bus costs an average of $72, and a train costs an average of $425.
Distance: 516 miles (831 km)
| Train | Most popular Flight | Bus | Driving |
|---|---|---|---|
$425 Average price | $184 Average price | $107 Average price Cheapest | $334 Average price (fuel + tolls) |
13h 5m Average total duration 12h 35m Onboard + 30m Additional time* | 5h 23m Average total duration Fastest 2h 23m Onboard + 3h 0m Additional time* | 20h 25m Average total duration 19h 55m Onboard + 30m Additional time* | 11h 28m Average total duration (door-to-door) |
- CO2 emissions | 2.5 - 5.0kg CO2 emissions | 0.8 - 2.1kg CO2 emissions Lowest | - CO2 emissions |
![]() Most popular train company | ![]() Most popular airline | ![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Strasbourg to Rome:
A bus is $77 less than a flight for this route with tickets for a flight from Strasbourg to Rome costing on average $184.
A bus is $319 less than a train for this route with tickets for a train from Strasbourg to Rome costing on average $425.
Other travel options to Rome take longer:
Train takes on average 12h 35m.
Bus takes on average 19h 55m.
Tickets start at around $425 compared to roughly $334 in fuel and tolls — a saving of about $-90.98. The journey takes 12h 35m versus 11h 28m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Trains from Strasbourg to Rome run on average 1 times per day, taking around 12h 35m. Cheap train tickets for this journey start at $425 but you can travel from only $72 by bus.
The earliest train runs at 00:01, the last at 22:55. The fastest train covers the 516 miles (831 km) distance in 9h 19m.
Distance 516 miles (831 km) |
Average train duration 12h 35m |
Cheapest ticket price $425 |
Trains per day 1 |
Fastest train 9h 19m |
First train 12:01 AM |
Last train 10:55 PM |
High Season Oct - Dec |
Low Season Apr - Jun |
Busiest Day Fri |
Least Busy Day Wed |
Best time to book 5 days |
Discover the best of Rome — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Rome trip today.
World-famous papal museums with the Sistine Chapel, Raphael Rooms, and major classical collections.
Outstanding ancient sculpture and mosaic museum housed in the Palazzo dei Conservatori and Palazzo Nuovo.
Celebrated villa museum with Bernini sculptures, Caravaggio paintings, and refined garden setting.
Elegant Baroque square with Bernini's fountains, lively atmosphere, and superb people-watching.
Historic square and gathering place at the Spanish Steps, ideal for classic city views and strolls.
Charming cobbled neighborhood filled with ivy-clad lanes, churches, nightlife, and local character.
Classic Roman pasta with guanciale, egg yolk, Pecorino Romano, and black pepper. A city icon known for rich flavor without cream.
Roman pasta with guanciale, tomato, and Pecorino Romano. A traditional Lazio staple tied to shepherd cooking and bold savory flavor.
Pasta with guanciale, Pecorino Romano, and black pepper. Considered one of Rome's oldest pasta dishes and prized for its simplicity.
Three-Michelin-star dining by Niko Romito at Bulgari Hotel Roma, offering refined Italian tasting menus in an elegant setting.
Historic trattoria in Testaccio known for classic Roman pasta and quinto quarto dishes in a lively, traditional setting.
Popular casual spot famed for Roman-style pizzas and fried starters. Bustling atmosphere and a long-standing local reputation.
Moderate for Europe: stays in central Rome are pricey, but transit is cheap and meals range from affordable pizza to costly tourist-area dining.
Service may be included via coperto or servizio. Round up or leave 5-10% at restaurants if service is good; round up in taxis; small change is fine at cafés.
Official public transport app
Roma Termini -> Piazza Di Spagna, Rome
Find answers to the most common questions about traveling from Strasbourg to Rome by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Rome, this guide helps you travel smarter and with confidence.

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