The cheapest and fastest trains from Milan Centrale to Syracuse station
Cheapest price
$208
Average price
$239
Fastest journey
14 h 14 m
Average duration
17 h 25 m
Trains per day
6
Distance
1064 km
The best way to find a cheap train ticket from Milan Centrale to Syracuse station is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Milan Centrale to Syracuse station will cost around $239 if you buy it on the day, but the cheapest tickets can be found for only $208.
It's difficult to get from Milan Centrale to Syracuse station without transferring at least once.
FRECCIAROSSA 9613+
Intercity 7278:30 AM14h14Milan Centrale10:44 PMSyracuse station$2081One-way1 transfer
Intercity 659 · Intercity 511+
InterCityNotte 19559:10 AM23h53Milan Centrale9:03 AMSyracuse station$2171One-way2 transfers
Intercity 597 · Intercity 594+
InterCityNotte 19591:48 PM23h38Milan Centrale1:26 PMSyracuse station$2201One-way2 transfers
FRECCIAROSSA 9555+
InterCityNotte 19555:10 PM15h53Milan Centrale9:03 AMSyracuse station$2381One-way1 transfer
FRECCIAROSSA 9663+
InterCityNotte 19597:35 PM17h51Milan Centrale1:26 PMSyracuse station$2531One-way1 transfer
FRECCIAROSSA 9613+
Intercity 7278:30 AM14h14Milan Centrale10:44 PMSyracuse station$2081One-way1 transfer
FRECCIAROSSA 9651 · FRECCIAROSSA 9555+
InterCityNotte 19555:35 PM15h28Milan Centrale9:03 AMSyracuse station$3011One-way2 transfers
FRECCIAROSSA 9555+
InterCityNotte 19555:10 PM15h53Milan Centrale9:03 AMSyracuse station$2381One-way1 transfer
FRECCIAROSSA 9663+
InterCityNotte 19597:35 PM17h51Milan Centrale1:26 PMSyracuse station$2531One-way1 transfer
Intercity 597 · Intercity 594+
InterCityNotte 19591:48 PM23h38Milan Centrale1:26 PMSyracuse station$2201One-way2 transfers
Travel Information
Compare train, bus, and flight for Milan Centrale to Syracuse station
Omio recommends booking the train as it is the most popular option from Milan Centrale to Syracuse station among Omio's users. If you are prioritising price take the flight with prices starting from $29. For those with little time consider booking a flight which can get you there in 1h 57m. The ticket price range depends on the travel mode: a flight costs an average of $29, and a train costs an average of $69.
Distance: 661 miles (1064 km)
Compare train with
Most popular Train | Bus | Flight | Driving |
|---|---|---|---|
$145 Average price | $84 Average price | $76 Average price Cheapest | $117 Average price (fuel + tolls) |
14h 46m Average total duration 14h 16m Onboard + 30m Additional time* | 23h 18m Average total duration 22h 48m Onboard + 30m Additional time* | 4h 57m Average total duration Fastest 1h 57m Onboard + 3h 0m Additional time* | 14h 28m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Milan Centrale to Syracuse station:
A flight is $9 (€7) less than a bus for this route with tickets for a bus from Milan Centrale to Syracuse station costing on average $84 (€67).
A flight is $70 (€56) less than a train for this route with tickets for a train from Milan Centrale to Syracuse station costing on average $145 (€116).
Other travel options to Syracuse station take longer:
Train takes on average 14h 16m.
Bus takes on average 22h 48m.
You'll arrive about 12m sooner (14h 16m by train vs 14h 28m by car). Tickets start at around $145 (€116) compared to roughly $117 (€93) in fuel and tolls — so you're paying a bit more, but getting hours of your day back, a city-centre arrival, and the freedom to work or relax instead of drive.
Direct services run with Intercity.
Driving makes more sense if you're travelling as a group (where fuel costs split several ways), want to stop along the way, or need a car once you arrive.
Live departures
Milan Centrale to Syracuse station train times
The table below shows live departures for Milan Centrale to Syracuse station trains for today, Wednesday, May 6. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 4:10 PM Milan Centrale | 15h51 | 8:01 AM Syracuse station | 0 transfersDirect | |
![]() | 6:10 PM Milan Centrale | 17h19 | 11:29 AM Syracuse station | 0 transfersDirect | |
![]() | 7:10 PM Milan Centrale | 19h38 | 2:48 PM Syracuse station | 0 transfersDirect | |
| Thursday, May 7 | |||||
FRECCIAROSSA 9613+ Intercity 727 | 8:30 AM Milan Centrale | 14h14 | 10:44 PM Syracuse station | 1 transfer | |
Intercity 659 · Intercity 511+ InterCityNotte 1955 | 9:10 AM Milan Centrale | 23h53 | 9:03 AM Syracuse station | 2 transfers | |
Intercity 597 · Intercity 594+ InterCityNotte 1959 | 1:48 PM Milan Centrale | 23h38 | 1:26 PM Syracuse station | 2 transfers | |
FRECCIAROSSA 9555+ InterCityNotte 1955 | 5:10 PM Milan Centrale | 15h53 | 9:03 AM Syracuse station | 1 transfer | |
FRECCIAROSSA 9651 · FRECCIAROSSA 9555+ InterCityNotte 1955 | 5:35 PM Milan Centrale | 15h28 | 9:03 AM Syracuse station | 2 transfers | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Milan Centrale to Syracuse station by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
May 07
May 08
May 09
May 10
May 11
May 12
May 13
Why should you book Milan Centrale to Syracuse station trains with Omio?
Why book with Omio vs Intercity Notte?
- Compare with other providers: On Omio, you can not only buy tickets for Intercity Notte, but also compare tickets for the likes of Intercity, Frecciarossa, Frecciargento or Italo to find the best option for your trip from Milan Centrale to Syracuse station.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Intercity Notte with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Milan Centrale to Syracuse station.
Journey information
Overview: Train from Milan Centrale to Syracuse station
Trains from Milan Centrale to Syracuse station run on average 7 times per day, taking around 14h 16m. Cheap train tickets for this journey start at $69 (€55) but you can travel from only $29 (€23) by flight.
There are 1 trains per day. The earliest train runs at 07:30, the last at 20:25. The fastest train covers the 661 miles (1064 km) distance in 14h 8m.
Distance 661 miles (1064 km) |
Average train duration 14h 16m |
Cheapest ticket price $69 (€55) |
Trains per day 7 |
Direct trains 1 |
Fastest train 14h 8m |
First train 7:30 AM |
Last train 8:25 PM |
Cheapest Month Sep |
Cheapest Day Tue |
High Season Jan - Mar |
Low Season Jul - Sep |
Busiest Day Fri |
Least Busy Day Fri |
Train companies: Intercity Notte, Intercity, Frecciarossa, Frecciargento, Italo from Milan Centrale to Syracuse station trainsIntercity Notte, Intercity, Frecciarossa, Frecciargento, Italo trains will get you between Milan Centrale and Syracuse station from $29 (€23). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Intercity Notte
Intercity
Frecciarossa
Frecciargento
Italo
FAQs: Trains from Milan Centrale to Syracuse station
Find answers to the most common questions about traveling from Milan Centrale to Syracuse station by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Syracuse station, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Milan Centrale to Syracuse station
- Mon - Sun: 05:50 - 22:20
- Free WiFi in the station.
- Provided by KiPoint and located on the ground floor, on the side of Piazza Luigi di Savoia. It is open every day from 06:00 to 23:00.
- Venchi
- Panzera Coffee
- Burger King
- Bar Motta
- Caffè Napoli
- VyTA Boulangerie
- Spontini
- Starbucks
- Dispensa Emilia
- McDonald's
- & many more
- Station is wheelchair accessible, has elevators and the Sala Blu, Trenitalia's office of assistance for disabled travelers, is next to Platform 4.
- Glam Hotel Milano
- NYX MIlan
- iQ Hotel Milano
- Mon - Sun: 05:50 - 22:20
- Located next to the ticket office on the ground floor in the shopping gallery.
- Metro lines: M2 (green), M3 (yellow)
- Tram lines: 1
- Bus lines: 5, 9, 10, 42, 81, 87, 152, 728, N26, NM2, NM3, Air Bus, Orio Shuttle
- Train lines: FR, FB, EC, Thello, XP2, R28, IC, ICN, RV, R, Regio, Italo
Most popular train connections from Milan Centrale
More options for your journey from Milan Centrale to Syracuse station
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