- Must visit
Pinacoteca di Brera
One of Milan’s premier art museums, known for masterpieces by Raphael, Caravaggio, and Mantegna in the historic Brera district.
Cheapest price
$143
Average price
$223
Fastest journey
17 h 36 m
Average duration
19 h 11 m
Trains per day
3
Distance
1064 km
The best way to find a cheap train ticket from Syracuse station to Milan Centrale is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Syracuse station to Milan Centrale will cost around $223 if you buy it on the day, but the cheapest tickets can be found for only $143.
Of the 3 trains that leave Syracuse station for Milan Centrale on Sun, Jun 21, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sun, Jun 21 the direct trains cover the 1064 km distance in an average of 19 h 11 m but if you time it right, some trains will get you there in just 17 h 36 m .
On Sun, Jun 21 the slowest trains will take 20 h 36 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
InterCityNotte 1962
InterCityNotte 36270+
FRECCIAROSSA 9520+
BUS L960A
InterCityNotte 1962+
FRECCIAROSSA 9574
InterCityNotte 36270+
FRECCIAROSSA 9520+
BUS L960A
InterCityNotte 1962+
FRECCIAROSSA 9574
InterCityNotte 1962Omio recommends booking the train as it is the most popular option from Syracuse station to Milan Centrale among Omio's users. If you are prioritising price take the bus with prices starting from $49. For those with little time consider booking a train which can get you there in 16h 3m. The ticket price range depends on the travel mode: a bus costs an average of $49, and a train costs an average of $67.
Distance: 661 miles (1064 km)
Most popular Train | Bus | Driving |
|---|---|---|
$126 Average price | $83 Average price Cheapest | $136 Average price (fuel + tolls) |
16h 33m Average total duration Fastest 16h 3m Onboard + 30m Additional time* | 19h 20m Average total duration 18h 50m Onboard + 30m Additional time* | 14h 41m Average total duration (door-to-door) |
![]() Most popular train company | ![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Syracuse station to Milan Centrale:
A bus is $43 (€35) less than a train for this route with tickets for a train from Syracuse station to Milan Centrale costing on average $126 (€103).
Other travel options to Milan Centrale take longer:
Bus takes on average 18h 50m.
Tickets start at around {cheapestPrice} compared to roughly {drivingPriceInCents} in fuel and tolls — a saving of about {savingsAmount}. The journey takes {durationInMinutes} versus {drivingDurationInMinutes} by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Direct services run with Intercity Notte, Intercity.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
The table below shows live departures for Syracuse station to Milan Centrale trains for tomorrow, Sunday, June 21. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
InterCityNotte 1962 | 1:29 PM Syracuse station | 20h36 | 10:05 AM Milan Centrale | 0 transfersDirect | |
InterCityNotte 1962+ FRECCIAROSSA 9574 | 1:29 PM Syracuse station | 19h21 | 8:50 AM Milan Centrale | 1 transfer | |
InterCityNotte 36270+ FRECCIAROSSA 9520+ BUS L960A | 7:14 PM Syracuse station | 17h36 | 12:50 PM Milan Centrale | 2 transfers | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Trains from Syracuse station to Milan Centrale run on average 7 times per day, taking around 16h 3m. Cheap train tickets for this journey start at $67 (€55) but you can travel from only $49 (€40) by bus.
There are 1 trains per day. The earliest train runs at 06:36, the last at 19:53. The fastest train covers the 661 miles (1064 km) distance in 20h 35m.
Distance 661 miles (1064 km) |
Average train duration 16h 3m |
Cheapest ticket price $67 (€55) |
Trains per day 7 |
Direct trains 1 |
Fastest train 20h 35m |
First train 6:36 AM |
Last train 7:53 PM |
Cheapest Month Oct |
Cheapest Day Sun |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Sun |
Least Busy Day Thu |
Discover the best of Milano Centrale — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Milano Centrale trip today.
One of Milan’s premier art museums, known for masterpieces by Raphael, Caravaggio, and Mantegna in the historic Brera district.
Italy’s largest science museum, featuring Leonardo-inspired displays, transport collections, and interactive exhibits in a former monastery.
A major museum of 20th-century Italian art facing Piazza del Duomo, especially noted for Futurist works and its central location.
Milan’s central square and the city’s main gathering point, ideal for first-time visitors and iconic city views.
A charming historic district known for elegant streets, art atmosphere, boutiques, and a classic Milanese walking experience.
Milan’s canal district, very popular for waterside walks, photos, and lively urban atmosphere, especially in the evening.
Milan’s signature saffron risotto, rich with butter and cheese, celebrated for its golden color and elegant, comforting flavor.
A classic Milanese breaded veal cutlet, traditionally cooked in butter and prized as one of the city’s most iconic dishes.
Braised veal shank, often served with risotto alla Milanese, valued for its tender meat and rich marrow-filled sauce.
Long-standing fine dining destination and one of Milan’s best-known vegetarian restaurants, refined and creative in style.
Well-known Milanese restaurant with a modern approach to Lombard classics such as risotto and mondeghili in a stylish setting.
Historic traditional trattoria known for classic Milanese dishes, old-world atmosphere, and a strong local reputation.
Prices are above the Italian average, especially near the station. Casual meals are manageable, but hotels and sit-down dining cost more.
Service is often included or covered by a coperto. Tipping is not mandatory; round up or leave EUR 1-5 for good service. Taxis can be rounded up.
Official public transport app
Milano Centrale, Milan -> Duomo di Milano, Milan
Find answers to the most common questions about traveling from Syracuse station to Milan Centrale by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Milan Centrale, this guide helps you travel smarter and with confidence.

Here are some other resources that might have the information you need