The cheapest and fastest trains from Milan Centrale to Karlsruhe Hbf
Cheapest price
$73
Average price
$73
Fastest journey
6 h 19 m
Average duration
6 h 19 m
Trains per day
1
Distance
395 km
The best way to find a cheap train ticket from Milan Centrale to Karlsruhe Hbf is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Milan Centrale to Karlsruhe Hbf will cost around $73 if you buy it on the day, but the cheapest tickets can be found for only $73.
Of the 1 trains that leave Milan Centrale for Karlsruhe Hbf on Sun, Dec 21, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sun, Dec 21 the direct trains cover the 395 km distance in an average of 6 h 19 m but if you time it right, some trains will get you there in just 6 h 19 m .
On Sun, Dec 21 the slowest trains will take 6 h 19 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Travel Information
Compare train, bus, and flight for Milan Centrale to Karlsruhe Hbf
Omio recommends booking the train as it is the most popular option from Milan Centrale to Karlsruhe Hbf among Omio's users. If you are prioritising price take the bus with prices starting from €21. For those with little time consider booking a flight which can get you there in 1h 6m. The ticket price range depends on the travel mode: a bus costs an average of €21, and a train costs an average of €50.
Distance: 245 miles (395 km)
Compare train with
Most popular Train | Bus | Flight |
|---|---|---|
€90 Average price | €38 Average price Cheapest | €62 Average price |
6h 43m Average total duration 6h 13m Onboard + 30m Additional time* | 9h 32m Average total duration 9h 2m Onboard + 30m Additional time* | 4h 6m Average total duration Fastest 1h 6m Onboard + 3h 0m Additional time* |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Live departures
Milan Centrale to Karlsruhe Hbf train times
The table below shows live departures for Milan Centrale to Karlsruhe Hbf trains for today, Saturday, December 20. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 9:10 AM Milan Centrale | 6h19 | 3:29 PM Karlsruhe Hbf | 0 transfersDirect | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Milan Centrale to Karlsruhe Hbf by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Dec 21
Dec 22
Dec 23
Dec 24
Dec 25
Dec 26
Dec 27
Why should you book Milan Centrale to Karlsruhe Hbf trains with Omio?
Deutsche Bahn (EC) as well as Trenitalia and Trenitalia EuroCity offer trains services from Milan Centrale to Karlsruhe Hbf. Omio is an official ticket reseller for all your travel options from Milan Centrale to Karlsruhe Hbf.
Why book with Omio vs Deutsche Bahn (EC)?
- Compare with other providers: On Omio, you can not only buy tickets for Deutsche Bahn (EC), but also compare tickets for the likes of Trenitalia and Trenitalia EuroCity to find the best option for your trip from Milan Centrale to Karlsruhe Hbf.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Deutsche Bahn (EC) with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Milan Centrale to Karlsruhe Hbf.
Why book with Omio over Trainline and Rail Europe?
- Multiple travel company options: While Deutsche Bahn (EC) tickets can be bought on Deutsche Bahn (EC)'s website or third party sellers, Omio allows you to compare with the likes of Trenitalia and Trenitalia EuroCity to help you choose the right option for your journey from Milan Centrale to Karlsruhe Hbf.
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Milan Centrale to Karlsruhe Hbf.
Journey information
Overview: Train from Milan Centrale to Karlsruhe Hbf
Trains from Milan Centrale to Karlsruhe Hbf run on average 1 times per day, taking around 6h 13m. Cheap train tickets for this journey start at $62 (€50) but you can travel from only $23 (€18) by flight.
There are 1 trains per day. The earliest train runs at 09:10, the last at 10:10. The fastest train covers the 245 miles (395 km) distance in 6h 19m.
Distance 245 miles (395 km) |
Average train duration 6h 13m |
Cheapest ticket price $62 (€50) |
Trains per day 1 |
Direct trains 1 |
Fastest train 6h 19m |
First train 09:10 |
Last train 10:10 |
Train companies: Deutsche Bahn, Trenitalia, Trenitalia EuroCity from Milan Centrale to Karlsruhe Hbf trainsDeutsche Bahn, Trenitalia, Trenitalia EuroCity trains will get you between Milan Centrale and Karlsruhe Hbf from $23 (€18). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Deutsche Bahn
A Bordrestaurant (restaurant car) where you can sit and eat.
A Bordbistro (bistro bar) with snacks, hot meals, and drinks to-go.
At-seat service in 1st class: staff will take your order and serve food/drinks directly to your seat.
Regional trains (RE / RB / S-Bahn):
No onboard catering.
You’re welcome to bring your own food and drinks.
Not included by default.
You can add a seat reservation when booking (recommended for busy routes).
Costs around €4.90 per seat (or €5.90 if booked separately later).
First Class:
Yes, always included in the ticket price.
Allowed for free if they can fit in a transport box (max. size: hand luggage).
Must stay in the box for the entire journey.
Large dogs:
Require a separate (paid) ticket — typically half the price of a regular second-class ticket.
Must be leashed and wear a muzzle while on the train.
Cannot sit on seats.
Assistance dogs:
Travel free of charge.
Do not need a muzzle or leash if medically not required.
Allowed to accompany the passenger at all times.
Trenitalia
Trenitalia EuroCity
FAQs: Trains from Milan Centrale to Karlsruhe Hbf
Find answers to the most common questions about traveling from Milan Centrale to Karlsruhe Hbf by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Karlsruhe Hbf, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Milan Centrale to Karlsruhe Hbf
- Mon - Sun: 05:50 - 22:20
- Free WiFi in the station.
- Provided by KiPoint and located on the ground floor, on the side of Piazza Luigi di Savoia. It is open every day from 06:00 to 23:00.
- Venchi
- Panzera Coffee
- Burger King
- Bar Motta
- Caffè Napoli
- VyTA Boulangerie
- Spontini
- Starbucks
- Dispensa Emilia
- McDonald's
- & many more
- Station is wheelchair accessible, has elevators and the Sala Blu, Trenitalia's office of assistance for disabled travelers, is next to Platform 4.
- Glam Hotel Milano
- NYX MIlan
- iQ Hotel Milano
- Mon - Sun: 05:50 - 22:20
- Located next to the ticket office on the ground floor in the shopping gallery.
- Metro lines: M2 (green), M3 (yellow)
- Tram lines: 1
- Bus lines: 5, 9, 10, 42, 81, 87, 152, 728, N26, NM2, NM3, Air Bus, Orio Shuttle
- Train lines: FR, FB, EC, Thello, XP2, R28, IC, ICN, RV, R, Regio, Italo
- Monday: 06:30 - 21:00
- Tuesday: 06:30 - 21:00
- Wednesday: 06:30 - 21:00
- Thursday: 06:30 - 21:00
- Friday: 06:30 - 21:00
- Saturday: 08:00 - 19:00
- Sunday: 09:00 - 20:00
- Vinarte
- Am Tiergarten
- Panorama
- Alter Brauhof
- Hotel Barbarossa
- Hotel Avisa
- Am Tiergarten
- Aparthotel Aijana
Most popular train connections from Milan Centrale
More options for your journey from Milan Centrale to Karlsruhe Hbf
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