- Must visit
Städel Museum
Major German art museum with masterpieces from Old Masters to modernism; a cornerstone stop on Frankfurt’s Museum Embankment.
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The cheapest and fastest trains from Mendrisio to Frankfurt am Main
Showing times, prices and bookable tickets for Sep 18
Cheapest price on Sep 18
$187
Average ticket price on Sep 18
$187
Fastest journey on Sep 18
6 h 40 m
Average journey duration on Sep 18
6 h 40 m
Trains on Sep 18
1
Distance
473 km
Cheap tickets
The best way to find a cheap train ticket from Mendrisio to Frankfurt am Main is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Mendrisio to Frankfurt am Main will cost around $187 if you buy it on the day, but the cheapest tickets can be found for only $187.
Fast trains
It's difficult to get from Mendrisio to Frankfurt am Main without transferring at least once.
12:04 PM6h40Mendrisio6:44 PMFrankfurt am Main$1871One-way1 transfer
- 12:04 PM6h40Mendrisio6:44 PMFrankfurt am Main$1871One-way1 transfer
Travel Information
Compare train for Mendrisio to Frankfurt am Main
Omio recommends booking the flight as it is the most popular option from Mendrisio to Frankfurt am Main among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $100 For those with little time, consider booking a flight, which has an average total journey time of 4h 31m. If you are seeking to minimise your carbon footprint, the bus is your best option, with estimated CO2 emissions of 0.5 - 1.2kg. Average ticket prices depend on the travel mode: a bus costs an average of $100, while a flight costs an average of $467.
Distance: 293 miles (473 km)
Compare flight with
Most popular Flight | Bus | Driving |
|---|---|---|
$467 Average price | $100 Average price Cheapest | $136 Average price (fuel + tolls) |
4h 31m Average total duration Fastest 2h 31m Onboard + 2h 0m Additional time* | 12h 52m Average total duration 12h 22m Onboard + 30m Additional time* | 6h 21m Average total duration (door-to-door) |
1.4 - 2.8kg CO2 emissions | 0.5 - 1.2kg CO2 emissions Lowest | - CO2 emissions |
 Most popular airline |  Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
The cheapest way to travel from Mendrisio to Frankfurt am Main is a bus with an average price of $100.
This is compared to other travel options from Mendrisio to Frankfurt am Main:
A bus is $366 less than a flight for this route with tickets for a flight from Mendrisio to Frankfurt am Main costing on average $467.
The fastest way to travel from Mendrisio to Frankfurt am Main is by flight with an average journey time of 2h 31m.
Other travel options to Frankfurt am Main take longer:
Bus takes on average 12h 22m.
Yes, you can take a train between Mendrisio and Frankfurt am Main.
We recommend using the train as it is the most popular way to get from Mendrisio to Frankfurt am Main among Omio's users.
Live departures
Mendrisio to Frankfurt am Main train times
The table below shows live departures for Mendrisio to Frankfurt am Main trains for tomorrow, Friday, September 18. You can also manually refresh the results below to see updated train journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| 12:04 PM Mendrisio | 6h40 | 6:44 PM Frankfurt am Main | 1 transfer | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Mendrisio to Frankfurt am Main by train
Compare train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Train from Mendrisio to Frankfurt am Main
Switzerland
Germany
Take a train from Mendrisio to Frankfurt am Main and enjoy the approximately 293 miles (473 km) long journey. Find schedules and pricing options for a convenient and affordable trip.
The earliest train runs at 02:25, the last at 20:51.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $71
Distance 293 miles (473 km) |
First train 2:25 AM |
Last train 8:51 PM |
High Season Jan - Mar |
Low Season Oct - Dec |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $71
Complete guide to Frankfurt am Main
Things to do in Frankfurt am Main
Discover the best of Frankfurt am Main — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Frankfurt am Main trip today.
- Must visit
Goethe-Haus und Goethe-Museum
Museum in Goethe’s birthplace presenting the writer’s life, era, and manuscripts; essential for literary and cultural history fans.
- Must visit
Senckenberg Naturmuseum
Large natural history museum with dinosaur skeletons, biodiversity displays, and strong geology exhibits; excellent for all ages.
- Must visit
Neue Altstadt
Rebuilt old town quarter between Römer and cathedral, blending historic layouts with new architecture; ideal for strolling and photos.
- Must visit
Museumsufer
Frankfurt’s riverside museum district and promenade, perfect for walking, major museums, and skyline views across the Main.
- Must visit
Palmengarten
Large inner-city palm garden with themed greenhouses and landscaped grounds; a relaxing break from museums and shopping.
- Vegetarian
- Gluten-free
Frankfurter Grüne Soße
Green sauce made with seven fresh herbs, usually served with boiled eggs and potatoes. It is a Frankfurt classic with protected regional status.
Frankfurter Würstchen
Pork sausage lightly smoked and traditionally served hot with potato salad, sauerkraut, or bread. It is one of Frankfurt’s signature sausages.
Frankfurter Rindswurst
Pressed and cured pork sausage, often sliced and served cold with bread, mustard, and pickles. It is a staple in Frankfurt cider taverns.
Lafleur
Two Michelin-starred dining with creative modern cuisine, extensive wine pairings, and a formal fine dining experience.
Restaurant Opéra
Refined restaurant in the old opera house area, known for modern European cuisine, polished service, and an elegant dining room.
Apfelwein Wagner
Historic apple wine tavern in Sachsenhausen known for Apfelwein, green sauce, and classic Frankfurt dishes in a lively traditional setting.
Euro (€)
Moderate for Germany: hotels can be pricey during trade fairs, but dining and public transport are reasonable for most tourists.
Average meal costs
- Budget
- €8-12 for fast food or simple takeaway.
- Mid-range
- €18-30 per person for a casual restaurant meal.
- Fine dining
- €70+ per person for upscale dining.
- Coffee
- €3-4.50 for a cappuccino.
Tipping culture
Round up or tip about 5-10% in restaurants for good service. Taxis are usually rounded up. Small change is common for cafes.
FAQs: Trains from Mendrisio to Frankfurt am Main
Find answers to the most common questions about traveling from Mendrisio to Frankfurt am Main by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Frankfurt am Main, this guide helps you travel smarter and with confidence.
The distance by train from Mendrisio to Frankfurt am Main is 293 miles (473 km).
The first train from Mendrisio to Frankfurt am Main leaves at 2:25 AM.
The last train from Mendrisio to Frankfurt am Main leaves at 8:51 PM.
Unfortunately, there is no night train available from Mendrisio to Frankfurt am Main.
The cheapest way to get from Mendrisio to Frankfurt am Main is by bus, with a cost of around $71.
Yes, the train journey from Mendrisio to Frankfurt am Main is scenic, offering picturesque views of the Swiss Alps, charming villages, and scenic landscapes, especially during the Swiss leg of the journey.
In Frankfurt am Main, visitors can enjoy panoramic views from the Main Tower and explore the vibrant Kleinmarkthalle for a variety of foods. The Senckenberg Natural History Museum offers fascinating dinosaur fossils, while a walk along the River Main provides scenic vistas. Shop at the lively Zeil or visit the Römer, a historic city hall. Art enthusiasts can explore the Städel Museum, while nature lovers will appreciate the Palmengarten. Delve into literary history at the Goethe House and admire the Gothic architecture of Frankfurt Cathedral.
Typically, spending 2 to 3 days in Frankfurt am Main is sufficient to explore its main attractions, such as the Römer, Städel Museum, and Palmengarten, while also enjoying the city's vibrant dining and shopping scenes.
No, you cannot take the train from Mendrisio to Frankfurt am Main.
Since both Mendrisio and Frankfurt am Main are in the Schengen Area, a passport is not required for European Union (EU) or Schengen-associated country citizens. A national ID card is sufficient.
Popular day trips by train from Frankfurt am Main include Heidelberg, Mannheim, Karlsruhe, Baden-Baden, Würzburg.
We recommend using the bus as it is the most popular way to get from Mendrisio to Frankfurt am Main among Omio's users.
Items not allowed on trains typically include hazardous materials such as explosives, flammable liquids, corrosive substances, and illegal drugs. Additionally, large or bulky items that may obstruct aisles or emergency exits, as well as pets without proper carriers, may be restricted. Specific prohibited items can vary by train operator and region, so please check the rules for your particular journey.
Germany uses the euro (€) as its currency. Travelers generally find it convenient to use cards, especially contactless payments, in cities and larger establishments. However, cash is still widely accepted and sometimes preferred in smaller shops, markets, and rural areas. Carrying some cash is recommended for flexibility.
In Frankfurt am Main, travelers should be cautious of pickpocketing, especially in crowded areas like train stations, public transport, and popular tourist spots. Common scams include distraction techniques where one person diverts attention while another steals belongings. It's also important to be wary of unofficial taxi drivers overcharging and to use licensed services. Staying alert in nightlife districts and avoiding poorly lit areas at night can help ensure safety.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
Most popular train connections from Mendrisio
More options for your journey from Mendrisio to Frankfurt am Main
Here are some other resources that might have the information you need
Most popular trains to and from Frankfurt am Main and Mendrisio
Most popular train connections to Frankfurt am Main
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