Travel Information
Compare bus and train for Mendrisio to Domodossola
Omio recommends booking the bus as it is the most popular option from Mendrisio to Domodossola among Omio's users. If you are prioritising price take the bus with prices starting from $17. For those with little time consider booking a train which can get you there in 2h 59m. The ticket price range depends on the travel mode: a bus costs an average of $17, and a train costs an average of $92.
Distance: 37 miles (60 km)
Compare train with
| Train | Most popular Bus |
|---|---|
$92 Average price | $17 Average price Cheapest |
3h 29m Average total duration Fastest 2h 59m Onboard + 30m Additional time* | 13h 50m Average total duration 13h 20m Onboard + 30m Additional time* |
Direct Options | Direct Options |
Compare prices and tickets Mendrisio to Domodossola by bus or train
Compare bus and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Train from Mendrisio to Domodossola
Trains from Mendrisio to Domodossola run on average 4 times per day, taking around 2h 59m. Cheap train tickets for this journey start at $92 (€75) but you can travel from only $17 (€14) by bus.
The earliest train runs at 04:56, the last at 20:07. The fastest train covers the 37 miles (60 km) distance in 2h 59m.
Distance 37 miles (60 km) |
Average train duration 2h 59m |
Cheapest ticket price $92 (€75) |
Trains per day 4 |
Fastest train 2h 59m |
First train 04:56 |
Last train 20:07 |
Train companies: Trenord from Mendrisio to Domodossola trainsTrenord trains will get you between Mendrisio and Domodossola from $17 (€14). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Trenord
FAQs: Trains from Mendrisio to Domodossola
Find answers to the most common questions about traveling from Mendrisio to Domodossola by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Domodossola, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Mendrisio to Domodossola
- 6:00 AM - 8:00 PM Monday - Sunday
- Free
- Parking is available 24/7 in the nearby parking lot.
- Ristorante Pizzeria Corona
- Osteria Lanterna
- Outside the main entrance.
- Ramps, restrooms.
- CHF 1
- Hotel Coronado
- Albergo Stazione Mendrisio
- Hotel Milano
- Located in the main hall
- 200 places, covered
- Europcar
- Located in the main hall
- Free
- Hall 1: main entrance, platform 1-3 for trains to Italy and regional destinations
- Train: S10, S40
- Bus: Several lines available
- 6:00 AM - 8:00 PM Monday - Sunday
- Free
- The car park is open 7 days a week, accessible from the main entrance.
- Ristorante La Meridiana
- Osteria Vecchio Borgo
- Outside the main entrance.
- Elevators, ramps.
- €1
- Hotel Corona
- Hotel Ristorante Eurossola
- Hotel Domodossola
- Located in the main hall
- Avis
- Europcar
- Located in the main hall
- Free
- Hall 1: main entrance, platform 1-5 for trains to Switzerland and regional destinations
- Train: Regional and Eurocity trains
- Bus: Several local lines available
Most popular train connections from Mendrisio
More options for your journey from Mendrisio to Domodossola
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