- Recommended
Museum of Osteopathic Medicine
Museum on osteopathic medicine history with medical artifacts and exhibits tied to Kirksville's role in the field's development.
The best way to find a cheap train ticket from Kansas City, MO to Kirksville, MO is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Kansas City, MO to Kirksville, MO will cost around $262 if you buy it on the day, but the cheapest tickets can be found for only $262.
On Sun, Nov 01, we found 1 trains from Kansas City, MO to Kirksville, MO, including 1 direct services.
On Sun, Nov 01 the direct trains cover the 210 km distance in an average of 2 h 3 m but if you time it right, some trains will get you there in just 2 h 3 m .
On Sun, Nov 01 the slowest trains will take 2 h 3 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

|
| ||||||||||||

|
| ||||||||||||
Trains from Kansas City, MO to Kirksville, MO run on average 1 times per day, taking around 2h 9m. Cheap train tickets for this journey start at $49 if you book in advance.
There are 1 trains per day. The earliest train runs at 07:01, the last at 19:19. The fastest train covers the 130 miles (210 km) distance in 2h 3m.
Plan this route
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Kansas City, MO to Kirksville, MO.
The table below shows live departures for Kansas City, MO to Kirksville, MO trains for tomorrow, Sunday, November 1. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 12:01 PM Kansas City, MO | 2h03 | 2:04 PM Kirksville, MO | 0 transfersDirect | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Trains from Kansas City, MO to Kirksville, MO with Amtrak. Night trains available on this route with Amtrak. High-speed trains available on this route with Amtrak. Use the details below to compare onboard facilities.
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
Discover the best of Kirksville, MO — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Kirksville, MO trip today.
Museum on osteopathic medicine history with medical artifacts and exhibits tied to Kirksville's role in the field's development.
University art gallery presenting rotating contemporary and regional exhibitions. A compact cultural stop on the Truman State campus.
Campus museum with changing exhibits on local history, culture, and teaching collections. Good for a deeper look at regional stories.
Large city park with lake views, trails, playgrounds, and event spaces. It is one of Kirksville's best outdoor places for a relaxed walk.
Downtown main street area with historic storefronts, shops, and the courthouse square. Ideal for strolling and seeing Kirksville's core.
Central civic green beside the courthouse used for events, gatherings, and seasonal displays. A practical stop while exploring downtown.
Breaded and deep-fried pork loin on a bun. A Midwest favorite in Missouri, prized for its crisp crust and hearty portions.
Slow-smoked pork shoulder, ribs, or burnt ends with sweet-tangy barbecue sauce. Missouri barbecue is a regional staple locals seek out.
Thin, yeast-leavened cracker crust pizza cut into squares, often topped with Provel-style cheese. A distinctly Missouri comfort food.
Popular casual diner for breakfast and lunch, with hearty Midwestern plates, pies, and a welcoming local feel.
Casual local barbecue spot known for smoked meats, classic sides, and a relaxed small-town atmosphere.
Established American restaurant serving steaks, seafood, and comfort food in a traditional, family-friendly setting.
Moderate for the U.S.; lodging and dining are usually cheaper than big cities, but limited transit means visitors often need a car.
Tip 15%-20% at restaurants, $1-$2 per drink at bars, round up or tip about 10% for taxis, and tipping at cafes is optional.
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Kirksville, MO.
Find answers to the most common questions about traveling from Kansas City, MO to Kirksville, MO by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Kirksville, MO, this guide helps you travel smarter and with confidence.

Most Kansas City, MO to Kirksville, MO trains use the Kansas City Station to station pair. Use this guide to compare Kansas City, MO and Kirksville, MO train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
Kansas City Station is 1 km from Kansas City city centre. Public transport options include:
Kansas City Station has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Car Rental, Information Desk, and Luggage Carts.
Food options include: Pierpont's at Union Station, Harvey's at Union Station
Free. ATMs are available in the train station.
Ticket office support is available at Kansas City Station. Information desks are located in the main hall.
Luggage storage is available at Kansas City Station. Lost and found is available at the station.
Available at Kansas City Station: Parking, Taxis, WC.
Available at Kansas City Station: Bike Parking, Car Rental.
Accessibility facilities are available at Kansas City Station: Ramps, restrooms.
Nearby hotels include The Westin Kansas City at Crown Center, Sheraton Kansas City Hotel at Crown Center, Hotel Kansas City.