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Compare prices and tickets Jacksonville, FL to Durham, NC by bus
Compare bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Train from Jacksonville, FL to Durham, NC
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $185 (€151)
Distance 422 miles (680 km) |
Average train duration 9h 25m |
Trains per day 1 |
First train 17:01 |
Last train 22:33 |
Key Takeaways
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $185 (€151)
Train companies: Amtrak from Jacksonville, FL to Durham, NC trainsAmtrak trains will get you between Jacksonville, FL and Durham, NC from $185 (€151). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Amtrak
About
Amtrak is the main passenger train operator in the United States, providing medium- and long-distance intercity services across 46 states and three Canadian provinces. Operating over 300 trains daily and serving more than 500 destinations, Amtrak connects cities and regions nationwide through routes such as the high-speed Acela in the Northeast Corridor, the scenic Coast Starlight along the West Coast, and the Empire Builder linking Chicago to the Midwest and the Pacific Northwest. Other notable services include the Northeast Regional, Keystone Service, and the unique Auto Train, which allows passengers to bring their cars onboard. Amtrak offers a variety of classes to suit different budgets and travel needs, including Coach, Business, First Class, and Sleeper Class with options like Roomettes, Bedrooms, and Bedroom Suites for overnight journeys. Ticket types include Saver, Value, Flexible, Business, and Premium. Onboard amenities vary by service but may include comfortable seating, Wi-Fi, power outlets, dining options, and lounge access on select trains. Popular routes include Washington, D.C.–Boston, San Diego–San Luis Obispo, San Jose–Sacramento, and Chicago–Seattle.
Luggage & cancellation policy
Amtrak frequency
1 a day
Luggage included
2 personal items and 2 carry-on bags included free
Luggage storage
Overhead racks, under seats, and designated luggage areas at end of cars
Cancellation Policy
Cancellation policies depend on ticket type and timing
Refund
Full refund if train is canceled by Amtrak
Amenities on board the train
Wifi
Food sold onboard
Café car with snacks, beverages, and light meals. Long-distance trains have full-service dining cars
Seat reservation
Included in ticket price for Business and First Class. Optional fee for Coach Class
Toilets
USB plugs
Accessibility
Wheelchair spaces, accessible restrooms, Red Cap assistance service, accessible platforms and stations
Pets
Small pets under 20 pounds allowed for $26 fee. Must be in carrier. Service animals travel free
Quiet zone
FAQs: Trains from Jacksonville, FL to Durham, NC
Find answers to the most common questions about traveling from Jacksonville, FL to Durham, NC by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Durham, NC, this guide helps you travel smarter and with confidence.

The train journey from Jacksonville, FL to Durham, NC offers a pleasant view of the southeastern U.S., featuring lush forests, rolling hills, and glimpses of charming small towns along the way.
The last train from Jacksonville, FL to Durham, NC leaves at 10:33 PM.
The cheapest way to get from Jacksonville, FL to Durham, NC is by bus, with a cost of around $185 (€151).
To fully explore Durham, NC, including its historic sites, cultural attractions, and vibrant downtown, spending around 2 to 3 days would be ideal.
There is no direct train service currently available from Jacksonville, FL to Durham, NC.
The first train from Jacksonville, FL to Durham, NC leaves at 5:01 PM.
Yes, you can take the train from Jacksonville, FL to Durham, NC.
Unfortunately, there is no night train available from Jacksonville, FL to Durham, NC.
The distance by train from Jacksonville, FL to Durham, NC is 422 miles (680 km).
The train station in Jacksonville, FL that goes to Durham, NC is Jacksonville station, Jacksonville, FL, which connects to Durham Station, Durham, NC.
There is no high speed train available from Jacksonville, FL to Durham, NC.
popular train stations
Popular train stations from Jacksonville, FL to Durham, NC
Jacksonville
Durham
The major train station for departures in Jacksonville is Jacksonville Station. Find all the information you need to know about services, amenities and connections at Jacksonville Station for your trip from Jacksonville to Durham.
Jacksonville Station






Amenities at train station
information
Ticket Office Hours
- 6:00 AM - 11:00 PM Monday - Sunday
Distance to city center
7 kmNumber of platforms
1Parking
- Parking is available at the station.
Taxis
- Outside the main entrance.
Accessibility
- Ramps, restrooms.
Information Desk
- Located in the main hall
Luggage Carts
- Free
Station Plan
- The station has an enclosed waiting area.
Public transit options for Jacksonville Station
- Bus: Several lines available
The major train station for arrivals in Durham is Durham Station. Find all the information you need to know about services, amenities and connections at Durham Station for your journey to Durham from Jacksonville.
Durham Station












Amenities at train station
information
Ticket Office Hours
- 6:30 AM - 9:00 PM Monday - Sunday
Number of platforms
2Wifi
- Free
Parking
- Parking is available nearby, with several public parking options in the vicinity.
Dining
- Parker and Otis
- Dame's Chicken & Waffles
Taxis
- Outside the main entrance.
Accessibility
- Ramps.
WC
- Free of charge
Hotel
- Durham Marriott City Center
- 21c Museum Hotel Durham
- Aloft Durham Downtown
Lost and Found Office
- Located in the main hall
Information Desk
- Located in the main hall
Luggage Carts
- Free
Station Plan
- Hall 1: main entrance, ticketing, and waiting area
- Hall 2: platform access
Public transit options for Durham Station
- Bus: GoDurham buses available
- Amtrak Thruway buses
More options for your journey from Jacksonville, FL to Durham, NC
Here are some other resources that might have the information you need
