Hamburg, Hauptbahnhof/Spitalerstraße to Karlsruhe Hbf train with Deutsche Bahn

Mon, Jun 22
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Deutsche Bahn
ÖBB | Nightjet
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ÖBB | Nightjet
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2,000+ travel companies
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The cheapest and fastest trains from Hamburg, Hauptbahnhof/Spitalerstraße to Karlsruhe Hbf

Showing times and prices for Jun 22

Cheapest price

$318

Average price

$318

Fastest journey

7 h 51 m

Average duration

7 h 51 m

Trains per day

1

Distance

519 km

Cheap tickets

The best way to find a cheap train ticket from Hamburg, Hauptbahnhof/Spitalerstraße to Karlsruhe Hbf is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Hamburg, Hauptbahnhof/Spitalerstraße to Karlsruhe Hbf will cost around $318 if you buy it on the day, but the cheapest tickets can be found for only $318.

Fast trains

Of the 1 trains that leave Hamburg, Hauptbahnhof/Spitalerstraße for Karlsruhe Hbf on Mon, Jun 22, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.

On Mon, Jun 22 the direct trains cover the 519 km distance in an average of 7 h 51 m but if you time it right, some trains will get you there in just 7 h 51 m .

On Mon, Jun 22 the slowest trains will take 7 h 51 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

  • Nightjet
    10:11 PM7h51
    Hamburg, Hauptbahnhof/Spitalerstraße
    6:02 AMKarlsruhe Hbf
    $3181One-way
    0 transfers

Travel Information

Compare train and bus for Hamburg, Hauptbahnhof/Spitalerstraße to Karlsruhe Hbf

Omio recommends booking the train as it is the most popular option from Hamburg, Hauptbahnhof/Spitalerstraße to Karlsruhe Hbf among Omio's users. If you are prioritising price take the bus with prices starting from $53. For those with little time consider booking a train which can get you there in 5h 57m. The ticket price range depends on the travel mode: a bus costs an average of $53, and a train costs an average of $103.

Distance: 322 miles (519 km)

Compare train with

Most popular
Train
Bus
Driving

$103

Average price

$53

Average price

Cheapest

$42

Average price

(fuel + tolls)

6h 27m

Average total duration

Fastest

5h 57m

Onboard

+

30m

Additional time*

10h 35m

Average total duration

10h 5m

Onboard

+

30m

Additional time*

6h 31m

Average total duration

(door-to-door)

Direct Options

Direct Options

Direct Options

The cheapest way to travel from Hamburg, Hauptbahnhof/Spitalerstraße to Karlsruhe Hbf is a bus with an average price of $53 (€44).

This is compared to other travel options from Hamburg, Hauptbahnhof/Spitalerstraße to Karlsruhe Hbf:

A bus is $49 (€40) less than a train for this route with tickets for a train from Hamburg, Hauptbahnhof/Spitalerstraße to Karlsruhe Hbf costing on average $103 (€84).

The fastest way to travel from Hamburg, Hauptbahnhof/Spitalerstraße to Karlsruhe Hbf is by train with an average journey time of 5h 57m.

Other travel options to Karlsruhe Hbf take longer:

Bus takes on average 10h 5m.

It's helpful to compare your options as there are 2 ways to travel between Hamburg, Hauptbahnhof/Spitalerstraße and Karlsruhe Hbf including taking a train and bus.
We recommend using the train as it is the most popular way to get from Hamburg, Hauptbahnhof/Spitalerstraße to Karlsruhe Hbf among Omio's users.
Take the train. It's meaningfully faster than driving, and the time saved usually justifies the price.

You'll arrive about 34m sooner (5h 57m by train vs 6h 31m by car). Tickets start at around $103 (€84) compared to roughly $42 (€34) in fuel and tolls — so you're paying a bit more, but getting hours of your day back, a city-centre arrival, and the freedom to work or relax instead of drive.

Direct services run with Deutsche Bahn, ÖBB | Nightjet.

Driving makes more sense if you're travelling as a group (where fuel costs split several ways), want to stop along the way, or need a car once you arrive.

Live departures

Hamburg, Hauptbahnhof/Spitalerstraße to Karlsruhe Hbf train times

The table below shows live departures for Hamburg, Hauptbahnhof/Spitalerstraße to Karlsruhe Hbf trains for today, Sunday, June 21. You can also manually refresh the results below to see updated train journeys.

Last updated at
ProviderDepartsDurationArrivesTransfers
Tickets
Nightjet10:11 PM Hamburg, Hauptbahnhof/Spitalerstraße
7h51
6:02 AM Karlsruhe Hbf0 transfersDirect

This is the last train of the day.

Find all the dates and times for this journey

Compare prices and tickets Hamburg, Hauptbahnhof/Spitalerstraße to Karlsruhe Hbf by train or bus

Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Mon
Jun 22
Tue
Jun 23
Wed
Jun 24
Thu
Jun 25
Fri
Jun 26
Sat
Jun 27
Sun
Jun 28

Why should you book Hamburg, Hauptbahnhof/Spitalerstraße to Karlsruhe Hbf trains with Omio?

Deutsche Bahn as well as ÖBB | Nightjet offer trains services from Hamburg, Hauptbahnhof/Spitalerstraße to Karlsruhe Hbf.
Omio is an official ticket reseller for all your travel options from Hamburg, Hauptbahnhof/Spitalerstraße to Karlsruhe Hbf.

Why book with Omio vs Deutsche Bahn?

  • Compare with other providers: On Omio, you can not only buy tickets for Deutsche Bahn, but also compare tickets for the likes of ÖBB | Nightjet to find the best option for your trip from Hamburg, Hauptbahnhof/Spitalerstraße to Karlsruhe Hbf.
  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare Deutsche Bahn with all available travel options, which are train and bus to ensure you get the best deal for traveling from Hamburg, Hauptbahnhof/Spitalerstraße to Karlsruhe Hbf.

Why book with Omio over Trainline or Wanderu?

  • Multiple modes of transport: Omio allows you to compare travel options including train and bus to find the ideal travel option from Hamburg, Hauptbahnhof/Spitalerstraße to Karlsruhe Hbf.

Journey information

Overview: Train from Hamburg, Hauptbahnhof/Spitalerstraße to Karlsruhe Hbf

GermanyGermany
GermanyGermany
Icon of train

Trains from Hamburg, Hauptbahnhof/Spitalerstraße to Karlsruhe Hbf run on average 4 times per day, taking around 5h 57m. Cheap train tickets for this journey start at $103 (€84) but you can travel from only $53 (€44) by bus.

There are 2 trains per day. The earliest train runs at 02:00, the last at 02:00. The fastest train covers the 322 miles (519 km) distance in 11h 26m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $53 (€44)
Distance
322 miles (519 km)
Average train duration
5h 57m
Cheapest ticket price
$103 (€84)
Trains per day
4
Direct trains
2
Fastest train
11h 26m
First train
2:00 AM
Last train
2:00 AM
Cheapest Month
Apr
Cheapest Day
Sat
High Season
Apr - Jun
Low Season
Jul - Sep
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $53 (€44)

Train companies: Deutsche Bahn, ÖBB | Nightjet from Hamburg, Hauptbahnhof/Spitalerstraße to Karlsruhe Hbf trainsDeutsche Bahn, ÖBB | Nightjet trains will get you between Hamburg, Hauptbahnhof/Spitalerstraße and Karlsruhe Hbf from $53 (€44). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.

Deutsche Bahn

About
Deutsche Bahn (DB) is Germany’s main train operator, running around 40,000 domestic and international services each day. Its fleet includes a variety of train types: high-speed ICE (Intercity Express) trains, reaching up to 300 km/h; IC (Intercity) and EC (EuroCity) trains for long-distance travel; and IRE (Interregio-Express), RE (Regional Express), and RB (Regionalbahn) services for regional and local connections. While bathrooms are standard on all trains, amenities such as onboard restaurants and free Wi-Fi are available only on certain train types and routes. DB offers a wide range of fares, including Super Saver, Saver, and Flexible tickets, along with discount cards like the BahnCard 25, 50, and 100. Additional options include single tickets, day tickets, and group tickets. Popular routes include Berlin–Munich, Hamburg–Frankfurt, Cologne–Stuttgart, Berlin–Dresden, and Hamburg–Cologne, as well as numerous regional services across Germany.
Luggage & cancellation policy
Average Duration
4h 45m
Cheapest Price
$104 (€85)
Deutsche Bahn frequency
5 a day
Luggage included
Passengers are allowed to bring hand luggage and one additional larger item free of charge, provided they can carry it themselves
Luggage storage
Luggage can be stored in overhead racks, under the seat, or in designated luggage areas near the doors or in the middle of the carriage.
Cancellation Policy
Tickets can be canceled based on their fare conditions as mentioned in what type of train tickets are refundable?
Refund
If DB cancels a train, passengers are entitled to a full refund of the ticket price.
Amenities on board the train
Wifi
Food sold onboard
Most ICE and many IC/EC trains have:
A Bordrestaurant (restaurant car) where you can sit and eat.
A Bordbistro (bistro bar) with snacks, hot meals, and drinks to-go.
At-seat service in 1st class: staff will take your order and serve food/drinks directly to your seat.
Regional trains (RE / RB / S-Bahn):
No onboard catering.
You’re welcome to bring your own food and drinks.
Seat reservation
Second Class:
Not included by default.
You can add a seat reservation when booking (recommended for busy routes).
Costs around €4.90 per seat (or €5.90 if booked separately later).
First Class:
Yes, always included in the ticket price.
Toilets
USB plugs
Accessibility
DB trains are equipped with facilities for passengers with reduced mobility, including wheelchair spaces, accessible restrooms, and assistance services.
Pets
Small pets (e.g. cats, small dogs, etc.):
Allowed for free if they can fit in a transport box (max. size: hand luggage).
Must stay in the box for the entire journey.
Large dogs:
Require a separate (paid) ticket — typically half the price of a regular second-class ticket.
Must be leashed and wear a muzzle while on the train.
Cannot sit on seats.
Assistance dogs:
Travel free of charge.
Do not need a muzzle or leash if medically not required.
Allowed to accompany the passenger at all times.
Quiet zone

ÖBB | Nightjet

About
ÖBB Nightjet is an Austrian train company that offers overnight services across Europe. It has a range of train types, including the EuroNight, CityNightLine and Nightjet, which all offer comfortable sleeping compartments and couchettes. The EuroNight is the most luxurious option, with private compartments and a restaurant car. The CityNightLine is a more affordable option, with compartments and couchettes, while the Nightjet is the most basic option, with couchettes and reclining seats. Ticket types include Economy, Comfort and Business, with the latter offering the most luxurious experience. Onboard facilities include Wi-Fi, power sockets, a restaurant car and a bar. The most popular routes for ÖBB Nightjet are from Vienna to Munich, Berlin, Zurich, Amsterdam, Prague and Budapest.
Luggage & cancellation policy
Average Duration
7h 51m
Cheapest Price
$318 (€260)
ÖBB | Nightjet frequency
1 a day
Luggage included
2 pieces of hand luggage and 1 piece of larger luggage included
Luggage storage
Luggage racks above seats, at end of carriages, and under seats. Special storage for bikes and ski equipment.
Cancellation Policy
Cancellation possible according to ticket type conditions
Refund
Full refund if train cancelled by ÖBB
Amenities on board the train
Wifi
Food sold onboard
Restaurant car or bistro available on most routes. Night trains offer breakfast service in sleeper and couchette cars.
Seat reservation
Seat reservations recommended but not mandatory. Additional fee applies. Free for certain ticket types and first class.
Toilets
USB plugs
Accessibility
Wheelchair spaces, accessible toilets, boarding assistance available with advance notice
Pets
Small pets in carriers travel free. Larger dogs need ticket (50% of 2nd class fare) and muzzle. Guide dogs free.
Quiet zone

FAQs: Trains from Hamburg, Hauptbahnhof/Spitalerstraße to Karlsruhe Hbf

Find answers to the most common questions about traveling from Hamburg, Hauptbahnhof/Spitalerstraße to Karlsruhe Hbf by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Karlsruhe Hbf, this guide helps you travel smarter and with confidence.

FAQs
Train ticket prices from Hamburg, Hauptbahnhof/Spitalerstraße to Karlsruhe Hbf can vary. The cheapest ticket starts at $103 (€84), while the average price is around $103 (€84).
The train from Hamburg, Hauptbahnhof/Spitalerstraße to Karlsruhe Hbf takes 11h 26m and runs 4 per day.
The first train from Hamburg, Hauptbahnhof/Spitalerstraße to Karlsruhe Hbf leaves at 2:00 AM.
The distance by train from Hamburg, Hauptbahnhof/Spitalerstraße to Karlsruhe Hbf is 322 miles (519 km).
The last train from Hamburg, Hauptbahnhof/Spitalerstraße to Karlsruhe Hbf leaves at 2:00 AM.
Yes, there is a direct train from Hamburg, Hauptbahnhof/Spitalerstraße to Karlsruhe Hbf. This service operates 2 times per day, provided by Deutsche Bahn, ÖBB | Nightjet.
Yes, there is a night train from Hamburg, Hauptbahnhof/Spitalerstraße to Karlsruhe Hbf.
The cheapest way to get from Hamburg, Hauptbahnhof/Spitalerstraße to Karlsruhe Hbf is by bus, with a cost of around $53 (€44).
Yes, you can take the train from Hamburg, Hauptbahnhof/Spitalerstraße to Karlsruhe Hbf.
Since both Hamburg, Hauptbahnhof/Spitalerstraße and Karlsruhe Hbf are in the Schengen Area, a passport is not required for European Union (EU) or Schengen-associated country citizens. A national ID card is sufficient.
Popular day trips by train from Karlsruhe Hbf include Strasbourg, Frankfurt am Main, Stuttgart, Freiburg im Breisgau, Mannheim.
We recommend using the train as it is the most popular way to get from Hamburg, Hauptbahnhof/Spitalerstraße to Karlsruhe Hbf among Omio's users.
Items not allowed on trains typically include hazardous materials such as explosives, flammable liquids, corrosive substances, and illegal drugs. Additionally, large or bulky items that may obstruct aisles or emergency exits, as well as pets without proper carriers, may be restricted. Specific prohibited items can vary by train operator and region, so please check the rules for your particular journey.
Yes, rail passes such as the Eurail Pass and Interrail Pass are valid on most trains in Germany, including Deutsche Bahn regional and long-distance services. Some high-speed trains may require a reservation fee even with a rail pass.
Germany uses the euro (€) as its currency. Travelers generally find it convenient to use cards, especially contactless payments, in cities and larger establishments. However, cash is still widely accepted and sometimes preferred in smaller shops, markets, and rural areas. Carrying some cash is recommended for flexibility.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

popular train stations

Popular train stations from Hamburg, Hauptbahnhof/Spitalerstraße to Karlsruhe Hbf

Most Hamburg, Hauptbahnhof/Spitalerstraße to Karlsruhe Hbf trains use the Hamburg Hbf to Karlsruhe Hbf station pair, with some services arriving at Karlsruhe-Durlach. Use this guide to compare Hamburg, Hauptbahnhof/Spitalerstraße and Karlsruhe Hbf train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.

Departure train stations in Hamburg
Arrival train stations in Karlsruhe
Hamburg HbfHachmannplatz 16, 20099 Hamburg, GermanyWifiLockersShoppingParkingDiningATMTaxisAccessibilityWCHotelLoungeLost and Found OfficeTicket OfficeBike ParkingBike RentalCar RentalInformation Desk
City-centre transport

Getting to Hamburg Hbf from Hamburg city centre

Hamburg Hbf is 2 km from Hamburg city centre. Public transport options include:

TrainS5, S3, S1 · 2m · $4 · every ~44 min
BusX35, 16, 606, 17, 6 · 3m · $2 · every ~47 min
SubwayU4, U2 · 1m · $2 · every ~33 min

Hamburg Hbf train station facilities and services

Hamburg Hbf has practical services for this route, including Wifi, Lockers, Shopping, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lounge, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, and Information Desk.

Food and drink

Food options include: Le Crobag, Burger King, Coffee Fellows, Havin Grill, KFC, Mr. CLOU, Starbucks, dean&david, SPAR Express, Pommesfreunde, & more

Wi-Fi and ATMs

Free Wi-Fi in the station. ATMs are available at Hamburg Hbf.

Tickets and information

Ticket office support is available at Hamburg Hbf. Information desks are located in the east hall on the opposite side of the DB ticket office.

Luggage and lost property

Luggage storage is the station has luggage lockers. Lost and found is available at the station.

Parking, taxis and toilets

Available at Hamburg Hbf: Parking, Taxis, WC.

Bike and car services

Available at Hamburg Hbf: Bike Parking, Bike Rental, Car Rental.

Accessibility

Accessibility facilities are available at Hamburg Hbf: Wheelchair friendly with lifts and ramps. Contact the Mobility Service Centre at +49 3065212888 or [email protected].

Shops, hotels and contact

Nearby hotels include Boutique 053 Hamburg Main Station, IntercityHotel Hamburg Hauptbahnhof, Park Hyatt Hamburg.

Hamburg-HarburgHamburg-Harburg, Hannoversche Str. 85, 21079 HamburgWifiLockersShoppingParkingDiningATMTaxisAccessibilityWCHotelLoungeLost and Found OfficeTicket OfficeBike ParkingBike RentalCar RentalInformation Desk
City-centre transport

Getting to Hamburg-Harburg from Hamburg city centre

Hamburg-Harburg is 13 km from Hamburg city centre. Public transport options include:

TrainS3, S5 · 10m · $4 · every ~25 min
S3, S5 · 18m · $4 · every ~14 min
Bus641 · 24m · $4

Hamburg-Harburg train station facilities and services

Hamburg-Harburg has practical services for this route, including Wifi, Lockers, Shopping, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lounge, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, and Information Desk.

Food and drink

Food options include: Café Bom Dia, Hünkar, Yoko Sushi Harburg, Mathewes Grill

Wi-Fi and ATMs

Wi-Fi is available at Hamburg-Harburg. ATMs are available at Hamburg-Harburg.

Tickets and information

Ticket office support is available at Hamburg-Harburg. Information desks are available at Hamburg-Harburg.

Luggage and lost property

Luggage storage is available at Hamburg-Harburg. Lost and found is available at the station.

Parking, taxis and toilets

Available at Hamburg-Harburg: Parking, Taxis, WC.

Bike and car services

Available at Hamburg-Harburg: Bike Parking, Bike Rental, Car Rental.

Accessibility

Accessibility facilities are available at Hamburg-Harburg.

Shops, hotels and contact

Nearby hotels include Hotel Panorama, Hotel Harburger Hof, Hotel Jeta, Hotel Süderelbe.

Hamburg-AltonaHamburg-Altona, Scheel-Plessen-Str. 17, 22765 HamburgWifiLockersShoppingParkingDiningATMTaxisAccessibilityWCHotelLoungeLost and Found OfficeTicket OfficeBike ParkingBike RentalCar RentalInformation Desk
City-centre transport

Getting to Hamburg-Altona from Hamburg city centre

Hamburg-Altona is 5 km from Hamburg city centre. Public transport options include:

TrainS3, S1, S7, S5 · 7m · $4 · every ~56 min
S3, S1, S7, S5 · 9m · $4 · every ~56 min
BusRe7 · 14m
16 · 18m · $4 · every ~11 min
2 · 20m · $4 · every ~13 min
16, 601 · 20m · $4 · every ~12 min

Hamburg-Altona train station facilities and services

Hamburg-Altona has practical services for this route, including Wifi, Lockers, Shopping, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lounge, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, and Information Desk.

Food and drink

Food options include: Ethio, Trattoria Toscana, Marta, Pavillon

Wi-Fi and ATMs

Wi-Fi is available at Hamburg-Altona. ATMs are available at Hamburg-Altona.

Tickets and information

Ticket office support is available at Hamburg-Altona. Information desks are available at Hamburg-Altona.

Luggage and lost property

Luggage storage is available at Hamburg-Altona. Lost and found is available at the station.

Parking, taxis and toilets

Available at Hamburg-Altona: Parking, Taxis, WC.

Bike and car services

Available at Hamburg-Altona: Bike Parking, Bike Rental, Car Rental.

Accessibility

Accessibility facilities are available at Hamburg-Altona.

Shops, hotels and contact

Nearby hotels include Schanzenstern Bio-Restaurant, Hotel Hamburg Altona, Hotel Central, Best Western Raphael Hotel Altona.

Most popular trains to and from Karlsruhe Hbf and Hamburg, Hauptbahnhof/Spitalerstraße

HomeTrainsTrains in GermanyHamburg, Hauptbahnhof/Spitalerstraße to Karlsruhe Hbf train

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