Travel Information
Compare bus and train for Hamburg, Hauptbahnhof/Spitalerstraße to Karlsruhe Hbf
Omio recommends booking the train as it is the most popular option from Hamburg, Hauptbahnhof/Spitalerstraße to Karlsruhe Hbf among Omio's users. If you are prioritising price take the bus with prices starting from €30. For those with little time consider booking a train which can get you there in 5h 34m. The ticket price range depends on the travel mode: a bus costs an average of €30, and a train costs an average of €34.
Distance: 322 miles (519 km)
Compare train with
Most popular Train | Bus |
|---|---|
€35 Average price | €34 Average price Cheapest |
6h 4m Average total duration Fastest 5h 34m Onboard + 30m Additional time* | 11h 50m Average total duration 11h 20m Onboard + 30m Additional time* |
Direct Options | Direct Options |
Compare prices and tickets Hamburg, Hauptbahnhof/Spitalerstraße to Karlsruhe Hbf by bus or train
Compare bus and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Train from Hamburg, Hauptbahnhof/Spitalerstraße to Karlsruhe Hbf
Trains from Hamburg, Hauptbahnhof/Spitalerstraße to Karlsruhe Hbf run on average 4 times per day, taking around 5h 34m. Cheap train tickets for this journey start at $42 (€34) but you can travel from only $37 (€30) by bus.
There are 1 trains per day. The earliest train runs at 04:30, the last at 05:17. The fastest train covers the 322 miles (519 km) distance in 11h 49m.
Distance 322 miles (519 km) |
Average train duration 5h 34m |
Cheapest ticket price $42 (€34) |
Trains per day 4 |
Direct trains 1 |
Fastest train 11h 49m |
First train 04:30 |
Last train 05:17 |
Train companies: Deutsche Bahn, Österreichische Bundesbahnen from Hamburg, Hauptbahnhof/Spitalerstraße to Karlsruhe Hbf trainsDeutsche Bahn, Österreichische Bundesbahnen trains will get you between Hamburg, Hauptbahnhof/Spitalerstraße and Karlsruhe Hbf from $37 (€30). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Deutsche Bahn
A Bordrestaurant (restaurant car) where you can sit and eat.
A Bordbistro (bistro bar) with snacks, hot meals, and drinks to-go.
At-seat service in 1st class: staff will take your order and serve food/drinks directly to your seat.
Regional trains (RE / RB / S-Bahn):
No onboard catering.
You’re welcome to bring your own food and drinks.
Not included by default.
You can add a seat reservation when booking (recommended for busy routes).
Costs around €4.90 per seat (or €5.90 if booked separately later).
First Class:
Yes, always included in the ticket price.
Allowed for free if they can fit in a transport box (max. size: hand luggage).
Must stay in the box for the entire journey.
Large dogs:
Require a separate (paid) ticket — typically half the price of a regular second-class ticket.
Must be leashed and wear a muzzle while on the train.
Cannot sit on seats.
Assistance dogs:
Travel free of charge.
Do not need a muzzle or leash if medically not required.
Allowed to accompany the passenger at all times.
Österreichische Bundesbahnen
FAQs: Trains from Hamburg, Hauptbahnhof/Spitalerstraße to Karlsruhe Hbf
Find answers to the most common questions about traveling from Hamburg, Hauptbahnhof/Spitalerstraße to Karlsruhe Hbf by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Karlsruhe Hbf, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Hamburg, Hauptbahnhof/Spitalerstraße to Karlsruhe Hbf
- Monday: 06:30 - 21:00
- Tuesday: 06:30 - 21:00
- Wednesday: 06:30 - 21:00
- Thursday: 06:30 - 21:00
- Friday: 06:30 - 21:00
- Saturday: 08:00 - 19:00
- Sunday: 09:00 - 20:00
- Vinarte
- Am Tiergarten
- Panorama
- Alter Brauhof
- Hotel Barbarossa
- Hotel Avisa
- Am Tiergarten
- Aparthotel Aijana
