Travel Information
Compare bus and train for Hamburg, Hauptbahnhof/Spitalerstraße to Mannheim Hbf
Omio recommends booking the train as it is the most popular option from Hamburg, Hauptbahnhof/Spitalerstraße to Mannheim Hbf among Omio's users. If you are prioritising price take the bus with prices starting from €46. For those with little time consider booking a train which can get you there in 5h 12m. The ticket price range depends on the travel mode: a bus costs an average of €46, and a train costs an average of €78.
Distance: 288 miles (465 km)
Compare train with
Most popular Train | Bus |
|---|---|
€81 Average price | €46 Average price Cheapest |
5h 42m Average total duration Fastest 5h 12m Onboard + 30m Additional time* | 8h 15m Average total duration 7h 45m Onboard + 30m Additional time* |
Direct Options | Direct Options |
Compare prices and tickets Hamburg, Hauptbahnhof/Spitalerstraße to Mannheim Hbf by bus or train
Compare bus and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Hamburg, Hauptbahnhof/Spitalerstraße to Mannheim Hbf trains with Omio?
Deutsche Bahn operates all train services from Hamburg, Hauptbahnhof/Spitalerstraße to Mannheim Hbf. Omio is the only official third party seller for Deutsche Bahn tickets.
Why book with Omio vs Deutsche Bahn?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Deutsche Bahn with all available travel options, which are bus and train to ensure you get the best deal for traveling from Hamburg, Hauptbahnhof/Spitalerstraße to Mannheim Hbf.
Why book with Omio over Trainline and Rail Europe?
- Official reseller: Deutsche Bahn tickets can only be bought on Omio or Deutsche Bahn's website as Omio is the only official third party seller for Deutsche Bahn tickets. Trainline, RailEurope, and Rail.Ninja do not sell Deutsche Bahn tickets as they are not official sellers.
- Multiple modes of transport: Omio allows you to compare travel options including bus and train to find the ideal travel option from Hamburg, Hauptbahnhof/Spitalerstraße to Mannheim Hbf.
Journey information
Overview: Train from Hamburg, Hauptbahnhof/Spitalerstraße to Mannheim Hbf
Trains from Hamburg, Hauptbahnhof/Spitalerstraße to Mannheim Hbf run on average 8 times per day, taking around 5h 12m. Cheap train tickets for this journey start at $97 (€78) but you can travel from only $57 (€46) by bus.
There are 3 trains per day. The earliest train runs at 03:20, the last at 20:01. The fastest train covers the 288 miles (465 km) distance in 4h 20m.
Distance 288 miles (465 km) |
Average train duration 5h 12m |
Cheapest ticket price $97 (€78) |
Trains per day 8 |
Direct trains 3 |
Fastest train 4h 20m |
First train 03:20 |
Last train 20:01 |
Train companies: Deutsche Bahn from Hamburg, Hauptbahnhof/Spitalerstraße to Mannheim Hbf trainsDeutsche Bahn trains will get you between Hamburg, Hauptbahnhof/Spitalerstraße and Mannheim Hbf from $57 (€46). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Deutsche Bahn
A Bordrestaurant (restaurant car) where you can sit and eat.
A Bordbistro (bistro bar) with snacks, hot meals, and drinks to-go.
At-seat service in 1st class: staff will take your order and serve food/drinks directly to your seat.
Regional trains (RE / RB / S-Bahn):
No onboard catering.
You’re welcome to bring your own food and drinks.
Not included by default.
You can add a seat reservation when booking (recommended for busy routes).
Costs around €4.90 per seat (or €5.90 if booked separately later).
First Class:
Yes, always included in the ticket price.
Allowed for free if they can fit in a transport box (max. size: hand luggage).
Must stay in the box for the entire journey.
Large dogs:
Require a separate (paid) ticket — typically half the price of a regular second-class ticket.
Must be leashed and wear a muzzle while on the train.
Cannot sit on seats.
Assistance dogs:
Travel free of charge.
Do not need a muzzle or leash if medically not required.
Allowed to accompany the passenger at all times.
FAQs: Trains from Hamburg, Hauptbahnhof/Spitalerstraße to Mannheim Hbf
Find answers to the most common questions about traveling from Hamburg, Hauptbahnhof/Spitalerstraße to Mannheim Hbf by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Mannheim Hbf, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Hamburg, Hauptbahnhof/Spitalerstraße to Mannheim Hbf
- Monday: 06:00 - 21:00
- Tuesday: 06:00 - 21:00
- Wednesday: 06:00 - 21:00
- Thursday: 06:00 - 21:00
- Friday: 06:00 - 21:00
- Saturday: 08:00 - 20:30
- Sunday: 08:00 - 20:30
- Safran Persisch-Afghanische Spezialitäten
- Corner
- Liman Döner
- Kaschmir-Tandoori
- Central
- Leonardo Hotel Mannheim City Center
- InterCityHotel Mannheim
- City Hotel
