Travel Information
Compare bus and flight for Buffalo, NY to Des Moines, IA
Omio recommends booking the bus as it is the most popular option from Buffalo, NY to Des Moines, IA among Omio's users. If you are prioritising price take the bus with prices starting from $124. For those with little time consider booking a flight which can get you there in 6h 22m. The ticket price range depends on the travel mode: a bus costs an average of $124, and a flight costs an average of $243.
Distance: 757 miles (1219 km)
Compare bus with
Most popular Bus | Flight |
|---|---|
$136 Average price Cheapest | $308 Average price |
23h 0m Average total duration 22h 30m Onboard + 30m Additional time* | 9h 22m Average total duration Fastest 6h 22m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options |
Compare prices and tickets Buffalo, NY to Des Moines, IA by bus or flight
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Train from Buffalo, NY to Des Moines, IA
Take a train from Buffalo, NY to Des Moines, IA and enjoy the approximately 757 miles (1219 km) long journey. Find schedules and pricing options for a convenient and affordable trip.
Distance 757 miles (1219 km) |
FAQs: Trains from Buffalo, NY to Des Moines, IA
Find answers to the most common questions about traveling from Buffalo, NY to Des Moines, IA by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Des Moines, IA, this guide helps you travel smarter and with confidence.

Most popular train connections from Buffalo, NY
More options for your journey from Buffalo, NY to Des Moines, IA
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