- Must visit
The Charleston Museum
America’s first museum with natural history, decorative arts, and Charleston stories across several historic sites.
Flights from Wilkes-Barre, PA to Charleston, SC depart on average 18 times per day, taking around 4h 22m. Cheap flight tickets for this journey start at $422 but you can travel from only $331 by train.
The earliest flight runs at 14:32, the last at 14:32. The fastest flight covers the 626 miles (1008 km) distance in 4h 22m. March is the cheapest month to fly.
Distance 626 miles (1008 km) |
Average flight duration 4h 22m |
Cheapest ticket price $422 |
Flights per day 18 |
Fastest flight 4h 22m |
First flight 2:32 PM |
Last flight 2:32 PM |
Cheapest Month Mar |
Cheapest Day Tue |
High Season Jan - Mar |
Low Season Jan - Mar |
Omio recommends booking the flight as it is the most popular option from Wilkes-Barre, PA to Charleston, SC among Omio's users. If you are prioritising price take the train with prices starting from $331. For those with little time consider booking a flight which can get you there in 4h 22m. The ticket price range depends on the travel mode: a train costs an average of $331, and a flight costs an average of $422.
Distance: 626 miles (1008 km)
Most popular Flight | Train | Driving |
|---|---|---|
$422 Average price | $331 Average price Cheapest | $145 Average price (fuel + tolls) |
7h 22m Average total duration Fastest 4h 22m Onboard + 3h 0m Additional time* | 24h 3m Average total duration 23h 33m Onboard + 30m Additional time* | 11h 21m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Wilkes-Barre, PA to Charleston, SC:
A train is $91 less than a flight for this route with tickets for a flight from Wilkes-Barre, PA to Charleston, SC costing on average $422.
Other travel options to Charleston, SC take longer:
Train takes on average 23h 33m.
Compare train and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Discover the best of Charleston, SC — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Charleston, SC trip today.
America’s first museum with natural history, decorative arts, and Charleston stories across several historic sites.
Leading Southern museum for contemporary art, known for bold exhibitions and strong local creative connections.
Powerful museum on Gadsden’s Wharf interpreting the African American journey and Charleston’s global significance.
Legendary waterfront promenade lined with antebellum homes, harbor breezes, and some of Charleston’s best views.
Historic defensive seawall and walk beside White Point Garden, ideal for sunset, mansions, and harbor panoramas.
Lively pedestrian-friendly market district known for crafts, architecture, and easy access to major downtown sights.
A Lowcountry rice dish with shrimp, sausage, or chicken simmered in rich broth. It reflects Charleston's Gullah Geechee and coastal cooking traditions.
Stone-ground grits cooked creamy and topped with local shrimp, often with bacon or gravy. It is one of Charleston's signature brunch and supper dishes.
A rich soup of blue crab, crab roe, cream, and sherry. This classic Charleston dish is closely tied to the city's historic seafood culture.
Historic fine-dining restaurant focused on seasonal Lowcountry cuisine. Known for polished Southern hospitality and dishes using regional ingredients.
Upscale seafood restaurant celebrated for local oysters and inventive Lowcountry dishes. Stylish, lively, and one of Charleston's best-known dining rooms.
Refined Southern restaurant in the Historic District, known for shrimp and grits, seafood, and polished service in an elegant setting.
Moderate for a US coastal city; hotels and dining in the historic district run higher, while transit is limited and many visitors rely on walking, rideshare, or car hire.
Tip 18-20% in restaurants, $1-2 per drink at bars, and 10-15% for taxis. Cafes often have tip screens; small tips are appreciated but optional.
Find answers to the most common questions about traveling from Wilkes-Barre, PA to Charleston, SC by flight. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest flight, the cheapest option, or tips for making the most of your visit at Charleston, SC, this guide helps you travel smarter and with confidence.

Most Wilkes-Barre, PA to Charleston, SC flights use the Wilkes-Barre/Scranton International Airport to Charleston International Airport airport pair. Use this guide to compare Wilkes-Barre, PA and Charleston, SC airports on this route, check city-centre transport, alongside checking practicalities like airport facilities and services.
Charleston International Airport is 2 km from Charleston city centre. Public transport options include:
Charleston International Airport has practical services for this route, including Wifi, Shopping, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lounge, Lost and Found Office, and Car Rental.
Food options include: Restaurants are available, including Charleston Beer Works (casual dining) and Caviar & Bas (café), located in the main terminal.
Free Wi-Fi available throughout the airport. ATMs are located in the main terminal.
Lost and found is available at the station.
Available at Charleston International Airport: Parking, Taxis, WC.
Available at Charleston International Airport: Car Rental.
Accessibility facilities are available at Charleston International Airport: Ramps, assistance.
Nearby hotels include Hotels like the DoubleTree by Hilton within walking distance..
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