- Must visit
The Charleston Museum
America’s first museum with natural history, decorative arts, and Charleston stories across several historic sites.
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Journey information
Overview: St. Louis, MO to Charleston, SC flight
USAUSA
Flights from St. Louis, MO to Charleston, SC depart on average 54 times per day, taking around 4h 36m. Cheap flight tickets for this journey start at $260 but you can travel from only $102 by bus.
The earliest flight runs at 05:00, the last at 19:05. The fastest flight covers the 702 miles (1131 km) distance in 3h 1m. October is the cheapest month to fly.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $102
Distance 702 miles (1131 km) |
Average flight duration 4h 36m |
Cheapest ticket price $260 |
Flights per day 54 |
Fastest flight 3h 1m |
First flight 5:00 AM |
Last flight 7:05 PM |
Cheapest Month Oct |
Cheapest Day Sat |
High Season Jul - Sep |
Low Season Oct - Dec |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $102
The cheapest and fastest flights from St. Louis, MO to Charleston, SC
Showing times, prices and bookable tickets for Sep 20
Cheapest price on Sep 20
$176
Average ticket price on Sep 20
$176
Fastest journey on Sep 20
4 h 45 m
Average journey duration on Sep 20
4 h 45 m
Flights on Sep 20
1
Distance
1131 km
Cheap tickets
The best way to find a cheap flight ticket from St. Louis, MO to Charleston, SC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from St. Louis, MO to Charleston, SC will cost around $176 if you buy it on the day, but the cheapest tickets can be found for only $176.
Fast flights
On Sun, Sep 20, we found 1 flights from St. Louis, MO to Charleston, SC, including 1 direct services.
On Sun, Sep 20 the direct flights cover the 1131 km distance in an average of 4 h 45 m but if you time it right, some flights will get you there in just 4 h 45 m .
On Sun, Sep 20 the longest flights will take 4 h 45 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
12:00 PM4h45St. Louis, MO4:45 PMCharleston, SC$1761One-way0 transfers
- 12:00 PM4h45St. Louis, MO4:45 PMCharleston, SC$1761One-way0 transfers
Travel Information
Compare bus and train for St. Louis, MO to Charleston, SC
Omio recommends booking the flight as it is the most popular option from St. Louis, MO to Charleston, SC among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $146 For those with little time, consider booking a flight, which has an average total journey time of 6h 36m. Average ticket prices depend on the travel mode: a bus costs an average of $146, while a train costs an average of $455.
Distance: 702 miles (1131 km)
Compare flight with
Most popular Flight | Train | Bus | Driving |
|---|---|---|---|
$384 Average price | $455 Average price | $146 Average price Cheapest | $173 Average price (fuel + tolls) |
6h 36m Average total duration Fastest 4h 36m Onboard + 2h 0m Additional time* | 33h 14m Average total duration 32h 44m Onboard + 30m Additional time* | 21h 50m Average total duration 21h 20m Onboard + 30m Additional time* | 13h 11m Average total duration (door-to-door) |
 Most popular airline |  Most popular train company |  Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
The cheapest way to travel from St. Louis, MO to Charleston, SC is a bus with an average price of $146.
This is compared to other travel options from St. Louis, MO to Charleston, SC:
A bus is $239 less than a flight for this route with tickets for a flight from St. Louis, MO to Charleston, SC costing on average $384.
A bus is $309 less than a train for this route with tickets for a train from St. Louis, MO to Charleston, SC costing on average $455.
The fastest way to travel from St. Louis, MO to Charleston, SC is by flight with an average journey time of 4h 36m.
Other travel options to Charleston, SC take longer:
Bus takes on average 21h 20m.
Train takes on average 32h 44m.
It's helpful to compare your options as there are 2 ways to travel between St. Louis, MO and Charleston, SC including taking a bus and train.
We recommend using the bus as it is the most popular way to get from St. Louis, MO to Charleston, SC among Omio's users.
Compare prices and tickets St. Louis, MO to Charleston, SC by bus or train
Compare bus and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Airlines: United, American Airlines, Republic Airlines, psa airlines from St. Louis, MO to Charleston, SCFind the best flights between St. Louis, MO to Charleston, SC with Omio's travel partners United, American Airlines, Republic Airlines, psa airlines from $102. We can find you the best deals, schedules and tickets when comparing and booking the best trip.
United
About
United Airlines, established in 1926, is a major U.S. airline headquartered in Chicago, Illinois. Operating an extensive domestic and international network, United serves more destinations than any other airline, connecting travelers across six continents. The airline's eight hubs include Chicago–O'Hare, Denver, Houston–Intercontinental, Los Angeles, Newark, San Francisco, Washington–Dulles, and Guam. As a founding member of the Star Alliance, United offers a comprehensive range of services, including regional flights through United Express, catering to both leisure and business travelers. The airline is committed to sustainability, investing in sustainable aviation fuel and innovative technologies to reduce its environmental impact.
Luggage & cancellation policy
Average United Duration
3h 52m
Cheapest United Price
$302
United frequency
30 a day
Luggage included
Carry-on baggage allowance is 7kg total (2 pieces max. ) for both Choice and Flex fares on United Airlines and Virgin Australia flights.
Additional luggage
Excess baggage fees apply for additional checked luggage beyond the standard allowance.
Luggage storage
Both airlines provide checked baggage services for storing luggage during flights.
Cancellation Policy
Cancellation fees apply per person, per booking, with specific fees for different fare types.
Refund
Not applicable to flights; however, full refunds are available if flights are canceled by the airline.
Pregnant on board
Pregnant passengers are permitted to travel, with specific guidelines and medical certificates required after a certain gestational period.
Unaccompagned minor
Unaccompanied minors are permitted to travel, with specific age restrictions and services provided.
Amenities on board the airplane
Wifi
Food sold onboard
Meals and snacks are included on international flights operated by United Airlines and Virgin Australia.
Seat reservation
Seat selection may incur additional fees, depending on the fare type and airline.
Toilets
USB plugs
Accessibility
United Airlines and Virgin Australia offer services to and within Australia, providing accessible travel options for passengers with mobility needs.
Bikes
Both airlines permit bicycles onboard, with specific guidelines and fees.
Pets
United Airlines and Virgin Australia allow pets onboard, subject to specific policies and fees.
American Airlines
About
American Airlines is one of the largest airlines in the world, connecting travelers to hundreds of destinations across the United States, Latin America, Europe, Asia, and beyond. Operating from major hubs such as Dallas/Fort Worth, Miami, and Charlotte, American offers a wide range of travel options. Passengers can choose from Economy with affordable fares, Premium Economy with extra space, or Business and First Class featuring flat-bed seats, premium dining, and lounge access. With a modern fleet and membership in the oneworld alliance, American Airlines combines global reach with comfort and reliability.
Luggage & cancellation policy
Average American Airlines Duration
3h 1m
Cheapest American Airlines Price
$260
American Airlines frequency
17 a day
Luggage included
1 carry-on bag (22 x 14 x 9 inches) and 1 personal item (18 x 14 x 8 inches) included in most fares
Additional luggage
Checked bags fees vary by route. First checked bag typically $30, second $40 on domestic flights
Cancellation Policy
Basic Economy tickets cannot be changed or refunded. Other fares allow changes with fee, refunds subject to fare rules.
Pregnant on board
Passengers can fly up to 36 weeks for single pregnancies, 32 weeks for multiple pregnancies. Medical certificate required within 7 days of departure if within 4 weeks of due date.
Unaccompagned minor
Children ages 5-14 can travel alone using American Airlines Unaccompanied Minor Service. Service fee is $150 each way.
Amenities on board the airplane
Wifi
Food sold onboard
USB plugs
Accessibility
American Airlines provides wheelchair assistance and special services for passengers with disabilities. Assistance must be requested at least 48 hours before departure.
Pets
Small dogs and cats allowed in cabin for $125 fee. Must be in approved carrier under seat. Service animals allowed.
psa airlines
About
PSA Airlines is an American regional airline and a wholly-owned subsidiary of the American Airlines Group, operating exclusively on behalf of American Airlines under the American Eagle brand. Headquartered in Charlotte, North Carolina, PSA Airlines operates over 800 daily flights to nearly 100 destinations across the United States. The airline maintains an all-jet fleet consisting of Bombardier CRJ700 and CRJ900 regional aircraft. With a team of over 5,000 employees, PSA Airlines plays a significant role in connecting smaller cities to major hubs within American Airlines' network.
Luggage & cancellation policy
Average psa airlines Duration
4h 2m
Cheapest psa airlines Price
$260
psa airlines frequency
3 a day
Luggage included
One carry-on bag and one personal item are allowed.
Additional luggage
Additional luggage can be checked for a fee, with weight limits up to 32kg (70lbs) for a single piece.
Cancellation Policy
PSA Airlines' cancellation policy depends on the timeframe of cancellation and ticket flexibility, with some flexible ticket options offering easier cancellations.
Refund
Passengers are entitled to a refund if the airline cancels a flight and they choose not to travel.
Amenities on board the airplane
Food sold onboard
Non-alcoholic beverages are complimentary in Economy Class, while alcoholic drinks and snack boxes can be purchased.
Seat reservation
Seat selection for standard seating is typically included, but preferred or Main Cabin Extra seats may require an additional fee.
Accessibility
Wheelchair assistance is available and should be requested at least 24 hours prior to flight departure.
Bikes
Bicycles can be carried as checked baggage if handlebars are turned sideways, pedals are removed, tires are deflated, and the bike is packed in a case or durable cardboard box.
Republic Airlines
About
Republic Airways is a major regional airline in the United States, operating as a subsidiary of Republic Airways Holdings. It provides scheduled passenger service for American Airlines (as American Eagle), Delta Air Lines (as Delta Connection), and United Airlines (as United Express) using a fleet of Embraer 170 and 175 regional jets. Headquartered in Indianapolis, Indiana, Republic Airways operates over 900 daily flights to more than 80 cities across the U.S. and Canada. The company is known for its large fleet of Embraer E-Jets and its state-of-the-art training facilities. In April 2025, Republic Airways Holdings announced its acquisition of Mesa Air Group, which is expected to create the second-largest regional carrier in the U.S.
Luggage & cancellation policy
Average Republic Airlines Duration
4h 20m
Cheapest Republic Airlines Price
$260
Republic Airlines frequency
4 a day
Luggage included
One carry-on bag (24 x 16 x 10) and one personal item
Additional luggage
Checked bags for a fee
Cancellation Policy
Tickets are non-refundable but may be cancelled for future flight credit minus applicable fees
Pregnant on board
Passengers can fly up to the end of their 36th week for single pregnancies and the end of their 32nd week for multiple pregnancies
Unaccompagned minor
Unaccompanied minor service is available for children ages 5-14. Must be booked directly with Republic Airlines
Amenities on board the airplane
USB plugs
Accessibility
Republic Airlines offers assistance for passengers with reduced mobility, including wheelchair services and priority boarding. Passengers are advised to request these services in advance to ensure availability and proper arrangements.
Complete guide to Charleston, SC
Things to do in Charleston, SC
Discover the best of Charleston, SC — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Charleston, SC trip today.
- Must visit
Gibbes Museum of Art
Leading Southern museum for contemporary art, known for bold exhibitions and strong local creative connections.
- Must visit
International African American Museum
Powerful museum on Gadsden’s Wharf interpreting the African American journey and Charleston’s global significance.
- Must visit
The Battery
Legendary waterfront promenade lined with antebellum homes, harbor breezes, and some of Charleston’s best views.
- Must visit
East Battery
Historic defensive seawall and walk beside White Point Garden, ideal for sunset, mansions, and harbor panoramas.
- Must visit
Charleston City Market
Lively pedestrian-friendly market district known for crafts, architecture, and easy access to major downtown sights.
- Gluten-free
Perloo
A Lowcountry rice dish with shrimp, sausage, or chicken simmered in rich broth. It reflects Charleston's Gullah Geechee and coastal cooking traditions.
- Gluten-free
Shrimp And Grits
Stone-ground grits cooked creamy and topped with local shrimp, often with bacon or gravy. It is one of Charleston's signature brunch and supper dishes.
She-Crab Soup
A rich soup of blue crab, crab roe, cream, and sherry. This classic Charleston dish is closely tied to the city's historic seafood culture.
Circa 1886 Restaurant
Historic fine-dining restaurant focused on seasonal Lowcountry cuisine. Known for polished Southern hospitality and dishes using regional ingredients.
The Ordinary
Upscale seafood restaurant celebrated for local oysters and inventive Lowcountry dishes. Stylish, lively, and one of Charleston's best-known dining rooms.
Magnolias
Refined Southern restaurant in the Historic District, known for shrimp and grits, seafood, and polished service in an elegant setting.
US Dollar ($)
Moderate for a US coastal city; hotels and dining in the historic district run higher, while transit is limited and many visitors rely on walking, rideshare, or car hire.
Average meal costs
- Budget
- $10-18 for fast food or casual lunch.
- Mid-range
- $25-45 per person for a restaurant meal.
- Fine dining
- $60+ per person for upscale restaurants.
- Coffee
- $4-6 for coffee or cappuccino.
Tipping culture
Tip 18-20% in restaurants, $1-2 per drink at bars, and 10-15% for taxis. Cafes often have tip screens; small tips are appreciated but optional.
FAQs: St. Louis, MO to Charleston, SC Flight
Find answers to the most common questions about traveling from St. Louis, MO to Charleston, SC by flight. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest flight, the cheapest option, or tips for making the most of your visit at Charleston, SC, this guide helps you travel smarter and with confidence.
Cheap plane tickets from St. Louis, MO to Charleston, SC can start from as little as $260 when you book in advance. The average flight ticket price for St. Louis, MO to Charleston, SC is $384 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by plane from St. Louis, MO to Charleston, SC is 3h 1m to travel the 702 miles (1131 km) long route. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest flight from St. Louis, MO to Charleston, SC leaves at 5:00 AM. Plan your trip with the Journey Planner from Omio.
The latest flight from St. Louis, MO to Charleston, SC leaves at 7:05 PM.
There are 54 flights a day from St. Louis, MO to Charleston, SC which require at least one change with American Airlines, Republic Airlines, United, psa airlines. Schedules can vary on holidays or weekends with fewer flights.
When taking a flight from St. Louis, MO to Charleston, SC, you can count on American Airlines, Republic Airlines, United, psa airlines for the best way to get you to Charleston, SC. You can also check all possible airlines who offer a service between St. Louis, MO and Charleston, SC and compare the amenities they offer before buying a plane ticket.
Flights from St. Louis, MO to Charleston, SC generally leave from St. Louis Lambert International Airport and arrive in Charleston International Airport.St. Louis Lambert International Airport is 1 miles (2 km) away from St. Louis, MO city centre and Charleston International Airport is 1 miles (2 km) from Charleston, SC city centre.
The cheapest month for a flight from St. Louis, MO to Charleston, SC is October.
It's helpful to compare your options as there are 2 ways to travel between St. Louis, MO and Charleston, SC including taking a bus and train.
Since neither St. Louis, MO nor Charleston, SC are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
There is a time difference of 1 h between St. Louis, MO and Charleston, SC all year round.
The best events to attend in Charleston, SC include:
- Spoleto Festival USA, a 17-day arts festival featuring performances in theater, music, and dance
- Charleston Wine + Food Festival, a culinary celebration showcasing local chefs and wines
- MOJA Arts Festival, a vibrant event celebrating African American and Caribbean culture through art, music, and food.
The best holidays to experience in Charleston, SC include:
- Spoleto Festival USA, vibrant arts and cultural performances throughout the city
- Memorial Day, the start of summer with various outdoor activities and events
- Labor Day, pleasant weather and a chance to enjoy the beach before fall.
The best season to visit Charleston, SC is Spring or Fall. The best weather to explore Charleston, SC is during March-May or September-November.
We recommend using the flight as it is the most popular way to get from St. Louis, MO to Charleston, SC among Omio's users.
For domestic flights we recommend to arrive 1.5 to 2 hours before departure. Please check the website of your departure airport if in doubt. Some airports may offer booking time slots for security checks or offer additional information on when to get there based on time of day.
Most airlines permit carry-on bags that fit within specific dimensions (e.g., 22 x 14 x 9 inches or 56 x 36 x 23 cm), including handles and wheels. Bags must fit in the overhead bin or under the seat in front of you.
Many airlines impose weight limits, commonly ranging between 7 kg (15 lbs) and 12 kg (26 lbs). Typically, passengers are allowed one carry-on bag and one personal item (for example a purse, laptop bag, or backpack). Personal items must fit under the seat in front of you. Budget Airlines (like Ryanair or Wizz Air) have stricter size and weight limits, often requiring fees for larger carry-ons. Full-Service Airlines have more lenient policies, sometimes including more spacious dimensions or higher weight limits depending on your ticket class.
The list of items prohibited on an airplane varies by country and airline, but in general, the following items are not allowed in carry-on or checked baggage: Weapons and self-defence items, sharp objects, flammable materials, explosives, toxic substances, or liquids over 100ml (except for medications and baby essentials). In checked baggage, firearms (without authorization), explosives, large lithium batteries, and hazardous chemicals are prohibited. Electronic cigarettes must be in carry-on bags, while alcohol and dry ice have restrictions. Always check with your airline for specific regulations.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Charleston, SC, travelers should be cautious of pickpocketing and petty theft, especially in crowded areas like the historic district and popular tourist spots. Beware of overly aggressive street vendors and unofficial taxi services that may overcharge. Additionally, travelers should avoid leaving valuables unattended and be cautious when using ride-sharing apps to ensure the driver matches the booking details. Staying aware of surroundings and using authorized services helps minimize safety risks.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular airports
Popular airports from St. Louis, MO to Charleston, SC
Most St. Louis, MO to Charleston, SC flights use the St. Louis Lambert International Airport to Charleston International Airport airport pair. Use this guide to compare St. Louis, MO and Charleston, SC airports on this route, check city-centre transport, alongside checking practicalities like airport facilities and services.
Departure airports in St. Louis
Arrival airports in Charleston
Which St. Louis, MO airport do flights to Charleston, SC leave from?
Flights from St. Louis, MO to Charleston, SC depart from St. Louis Lambert International Airport. The airport is 1 miles (2 km) from St. Louis, MO city centre at 10701 Lambert Intertiol Blvd, St. Louis, MO 63145, USA.
St. Louis Lambert International Airport (STL)10701 Lambert Intertiol Blvd, St. Louis, MO 63145, USA
City-centre transport
Getting to St. Louis Lambert International Airport from St. Louis city centre
St. Louis Lambert International Airport is 2 km from St. Louis city centre. Public transport options include:
TrainMlr · 31m · $4 · every ~7 min
BusGreyhound US1210 · 25m · $2
St. Louis Lambert International Airport airport facilities and services
St. Louis Lambert International Airport has practical services for this route, including Wifi, Shopping, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Shower, Lounge, Lost and Found Office, and Car Rental.
Food and drink
Food options include: Restaurants in both terminals, including fast food and sit-down options like Starbucks and Chili's
Wi-Fi and ATMs
Free Wi-Fi available throughout the airport. ATMs are located in both terminals.
Luggage and lost property
Lost and found is available at the station.
Parking, taxis and toilets
Available at St. Louis Lambert International Airport: Parking, Taxis, WC.
Bike and car services
Available at St. Louis Lambert International Airport: Car Rental.
Accessibility
Accessibility facilities are available at St. Louis Lambert International Airport: Elevators, ramps.
Shops, hotels and contact
Nearby hotels include Hotels nearby, such as Marriott St. Louis Airport within walking distance..
Which Charleston, SC airport do flights from St. Louis, MO arrive at?
Flights from St. Louis, MO to Charleston, SC arrive at Charleston International Airport. Charleston International Airport is 1 miles (3 km) from Charleston, SC city centre.
Charleston International Airport (CHS)5500 Intertiol Blvd, North Charleston, SC 29418, USA
City-centre transport
Getting to Charleston International Airport from Charleston city centre
Charleston International Airport is 2 km from Charleston city centre. Public transport options include:
BusXp3 · 18m
Xp3 · 20m
11 · 1h 31m · $5 · every ~2 min
Charleston International Airport airport facilities and services
Charleston International Airport has practical services for this route, including Wifi, Shopping, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lounge, Lost and Found Office, and Car Rental.
Food and drink
Food options include: Restaurants are available, including Charleston Beer Works (casual dining) and Caviar & Bas (café), located in the main terminal.
Wi-Fi and ATMs
Free Wi-Fi available throughout the airport. ATMs are located in the main terminal.
Luggage and lost property
Lost and found is available at the station.
Parking, taxis and toilets
Available at Charleston International Airport: Parking, Taxis, WC.
Bike and car services
Available at Charleston International Airport: Car Rental.
Accessibility
Accessibility facilities are available at Charleston International Airport: Ramps, assistance.
Shops, hotels and contact
Nearby hotels include Hotels like the DoubleTree by Hilton within walking distance..
Most popular flights from St. Louis, MO
More options for your journey from St. Louis, MO to Charleston, SC
Here are some other resources that might have the information you need
Most popular flights to and from Charleston, SC and St. Louis, MO
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