St. Louis, MO STL to Charleston, SC CHS Flights

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Journey information

Overview: St. Louis, MO to Charleston, SC flight

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Flights from St. Louis, MO to Charleston, SC depart on average 36 times per day, taking around 5h 45m. Cheap flight tickets for this journey start at $177 (€144) but you can travel from only $132 (€108) by bus.

The earliest flight runs at 05:00, the last at 19:05. The fastest flight covers the 702 miles (1131 km) distance in 4h 45m. October is the cheapest month to fly.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $132 (€108)
Distance
702 miles (1131 km)
Average flight duration
5h 45m
Cheapest ticket price
$177 (€144)
Flights per day
36
Fastest flight
4h 45m
First flight
5:00 AM
Last flight
7:05 PM
Cheapest Month
Oct
Cheapest Day
Sat
High Season
Jul - Sep
Low Season
Apr - Jun
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $132 (€108)

Travel Information

Compare bus, train, and flight for St. Louis, MO to Charleston, SC

Omio recommends booking the flight as it is the most popular option from St. Louis, MO to Charleston, SC among Omio's users. If you are prioritising price take the bus with prices starting from $132. For those with little time consider booking a flight which can get you there in 5h 45m. The ticket price range depends on the travel mode: a bus costs an average of $132, and a train costs an average of $490.

Distance: 702 miles (1131 km)

Compare flight with

Most popular
Flight
Bus
Train
Driving

$208

Average price

$139

Average price

Cheapest

$495

Average price

$172

Average price

(fuel + tolls)

8h 45m

Average total duration

Fastest

5h 45m

Onboard

+

3h 0m

Additional time*

26h 0m

Average total duration

25h 30m

Onboard

+

30m

Additional time*

43h 22m

Average total duration

42h 52m

Onboard

+

30m

Additional time*

13h 11m

Average total duration

(door-to-door)

Direct Options

Direct Options

Direct Options

Direct Options

The cheapest way to travel from St. Louis, MO to Charleston, SC is a bus with an average price of $139 (€113).

This is compared to other travel options from St. Louis, MO to Charleston, SC:

A bus is $69 (€56) less than a flight for this route with tickets for a flight from St. Louis, MO to Charleston, SC costing on average $208 (€169).

A bus is $357 (€291) less than a train for this route with tickets for a train from St. Louis, MO to Charleston, SC costing on average $495 (€403).

The fastest way to travel from St. Louis, MO to Charleston, SC is by flight with an average journey time of 5h 45m.

Other travel options to Charleston, SC take longer:

Bus takes on average 25h 30m.

Train takes on average 42h 52m.

It's helpful to compare your options as there are 3 ways to travel between St. Louis, MO and Charleston, SC including taking a bus, train, and flight.
We recommend using the bus as it is the most popular way to get from St. Louis, MO to Charleston, SC among Omio's users.

Compare prices and tickets St. Louis, MO to Charleston, SC by bus, train, or flight

Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Wed
Aug 05
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Aug 06
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Aug 07
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Complete guide to Charleston, SC

Things to do in Charleston, SC

Discover the best of Charleston, SC — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Charleston, SC trip today.

  • Must visit

The Charleston Museum

America’s first museum with natural history, decorative arts, and Charleston stories across several historic sites.

  • Must visit

Gibbes Museum of Art

Leading Southern museum for contemporary art, known for bold exhibitions and strong local creative connections.

  • Must visit

International African American Museum

Powerful museum on Gadsden’s Wharf interpreting the African American journey and Charleston’s global significance.

US Dollar ($)

Moderate for a US coastal city; hotels and dining in the historic district run higher, while transit is limited and many visitors rely on walking, rideshare, or car hire.

Average meal costs

Budget
$10-18 for fast food or casual lunch.
Mid-range
$25-45 per person for a restaurant meal.
Fine dining
$60+ per person for upscale restaurants.
Coffee
$4-6 for coffee or cappuccino.

Tipping culture

Tip 18-20% in restaurants, $1-2 per drink at bars, and 10-15% for taxis. Cafes often have tip screens; small tips are appreciated but optional.

FAQs: St. Louis, MO to Charleston, SC Flight

Find answers to the most common questions about traveling from St. Louis, MO to Charleston, SC by flight. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest flight, the cheapest option, or tips for making the most of your visit at Charleston, SC, this guide helps you travel smarter and with confidence.

FAQs
Cheap plane tickets from St. Louis, MO to Charleston, SC can start from as little as $177 (€144) when you book in advance. The average flight ticket price for St. Louis, MO to Charleston, SC is $208 (€169) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by plane from St. Louis, MO to Charleston, SC is 4h 45m to travel the 702 miles (1131 km) long route. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest flight from St. Louis, MO to Charleston, SC leaves at 5:00 AM. Plan your trip with the Journey Planner from Omio.
The latest flight from St. Louis, MO to Charleston, SC leaves at 7:05 PM.
Flights from St. Louis, MO to Charleston, SC generally leave from St. Louis Lambert International Airport and arrive in Charleston International Airport.St. Louis Lambert International Airport is 1 miles (2 km) away from St. Louis, MO city centre and Charleston International Airport is 1 miles (2 km) from Charleston, SC city centre.
The cheapest month for a flight from St. Louis, MO to Charleston, SC is October.
It's helpful to compare your options as there are 3 ways to travel between St. Louis, MO and Charleston, SC including taking a bus, train, and flight.
Since neither St. Louis, MO nor Charleston, SC are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
There is a time difference of 1 h between St. Louis, MO and Charleston, SC all year round.
The best events to attend in Charleston, SC include:
  • Spoleto Festival USA, a 17-day arts festival featuring performances in theater, music, and dance
  • Charleston Wine + Food Festival, a culinary celebration showcasing local chefs and wines
  • MOJA Arts Festival, a vibrant event celebrating African American and Caribbean culture through art, music, and food.
The best holidays to experience in Charleston, SC include:
  • Spoleto Festival USA, vibrant arts and cultural performances throughout the city
  • Memorial Day, the start of summer with various outdoor activities and events
  • Labor Day, pleasant weather and a chance to enjoy the beach before fall.
The best season to visit Charleston, SC is Spring or Fall. The best weather to explore Charleston, SC is during March-May or September-November.
We recommend using the bus as it is the most popular way to get from St. Louis, MO to Charleston, SC among Omio's users.
For domestic flights we recommend to arrive 1.5 to 2 hours before departure. Please check the website of your departure airport if in doubt. Some airports may offer booking time slots for security checks or offer additional information on when to get there based on time of day.
Most airlines permit carry-on bags that fit within specific dimensions (e.g., 22 x 14 x 9 inches or 56 x 36 x 23 cm), including handles and wheels. Bags must fit in the overhead bin or under the seat in front of you.
Many airlines impose weight limits, commonly ranging between 7 kg (15 lbs) and 12 kg (26 lbs). Typically, passengers are allowed one carry-on bag and one personal item (for example a purse, laptop bag, or backpack). Personal items must fit under the seat in front of you. Budget Airlines (like Ryanair or Wizz Air) have stricter size and weight limits, often requiring fees for larger carry-ons. Full-Service Airlines have more lenient policies, sometimes including more spacious dimensions or higher weight limits depending on your ticket class.
The list of items prohibited on an airplane varies by country and airline, but in general, the following items are not allowed in carry-on or checked baggage: Weapons and self-defence items, sharp objects, flammable materials, explosives, toxic substances, or liquids over 100ml (except for medications and baby essentials). In checked baggage, firearms (without authorization), explosives, large lithium batteries, and hazardous chemicals are prohibited. Electronic cigarettes must be in carry-on bags, while alcohol and dry ice have restrictions. Always check with your airline for specific regulations.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Charleston, SC, travelers should be cautious of pickpocketing and petty theft, especially in crowded areas like the historic district and popular tourist spots. Beware of overly aggressive street vendors and unofficial taxi services that may overcharge. Additionally, travelers should avoid leaving valuables unattended and be cautious when using ride-sharing apps to ensure the driver matches the booking details. Staying aware of surroundings and using authorized services helps minimize safety risks.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

popular airports

Popular airports from St. Louis, MO to Charleston, SC

Most St. Louis, MO to Charleston, SC flights use the St. Louis Lambert International Airport to Charleston International Airport airport pair. Use this guide to compare St. Louis, MO and Charleston, SC airports on this route, check city-centre transport, alongside checking practicalities like airport facilities and services.

Departure airports in St. Louis
Arrival airports in Charleston

Which St. Louis, MO airport do flights to Charleston, SC leave from?

Flights from St. Louis, MO to Charleston, SC depart from St. Louis Lambert International Airport. The airport is 1 miles (2 km) from St. Louis, MO city centre at 10701 Lambert Intertiol Blvd, St. Louis, MO 63145, USA.
St. Louis Lambert International Airport (STL)10701 Lambert Intertiol Blvd, St. Louis, MO 63145, USAWifiShoppingParkingDiningATMTaxisAccessibilityWCHotelShowerLoungeLost and Found OfficeCar Rental
City-centre transport

Getting to St. Louis Lambert International Airport from St. Louis city centre

St. Louis Lambert International Airport is 2 km from St. Louis city centre. Public transport options include:

TrainMlr · 31m · $4 · every ~7 min
BusGreyhound US1210 · 25m · $2

St. Louis Lambert International Airport airport facilities and services

St. Louis Lambert International Airport has practical services for this route, including Wifi, Shopping, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Shower, Lounge, Lost and Found Office, and Car Rental.

Food and drink

Food options include: Restaurants in both terminals, including fast food and sit-down options like Starbucks and Chili's

Wi-Fi and ATMs

Free Wi-Fi available throughout the airport. ATMs are located in both terminals.

Luggage and lost property

Lost and found is available at the station.

Parking, taxis and toilets

Available at St. Louis Lambert International Airport: Parking, Taxis, WC.

Bike and car services

Available at St. Louis Lambert International Airport: Car Rental.

Accessibility

Accessibility facilities are available at St. Louis Lambert International Airport: Elevators, ramps.

Shops, hotels and contact

Nearby hotels include Hotels nearby, such as Marriott St. Louis Airport within walking distance..

More options for your journey from St. Louis, MO to Charleston, SC

Here are some other resources that might have the information you need

Most popular flights to and from Charleston, SC and St. Louis, MO

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