- Must visit
Museo del Canal Interoceánico de Panamá
Museum in a former convent in Casco Antiguo presenting pre-Columbian, colonial, and modern artifacts for a concise overview of Panama's history.
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Journey information
Overview: Santo Domingo to Panama City flight
Dominican Republic
Panama
Flights from Santo Domingo to Panama City depart on average 12 times per day, taking around 3h 35m. Cheap flight tickets for this journey start at $320 if you book in advance.
There are 5 flights per day. The earliest flight runs at 02:55, the last at 23:13. The fastest flight covers the 916 miles (1475 km) distance in 2h 32m. July is the cheapest month to fly.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 916 miles (1475 km) |
Average flight duration 3h 35m |
Cheapest ticket price $320 |
Flights per day 12 |
Direct flights 5 |
Fastest flight 2h 32m |
First flight 2:55 AM |
Last flight 11:13 PM |
Cheapest Month Jul |
Cheapest Day Sat |
High Season Jul - Sep |
Low Season Jan - Mar |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
The cheapest and fastest flights from Santo Domingo to Panama City
Showing times, prices and bookable tickets for Sep 19
Cheapest price on Sep 19
$342
Average ticket price on Sep 19
$342
Fastest journey on Sep 19
21 h 30 m
Average journey duration on Sep 19
21 h 30 m
Flights on Sep 19
1
Distance
1475 km
Cheap tickets
The best way to find a cheap flight ticket from Santo Domingo to Panama City is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Santo Domingo to Panama City will cost around $342 if you buy it on the day, but the cheapest tickets can be found for only $342.
Fast flights
On Sat, Sep 19, we found 1 flights from Santo Domingo to Panama City, including 1 direct services.
On Sat, Sep 19 the direct flights cover the 1475 km distance in an average of 21 h 30 m but if you time it right, some flights will get you there in just 21 h 30 m .
On Sat, Sep 19 the longest flights will take 21 h 30 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
4:45 PM21h30Santo Domingo2:15 PMPanama City$3421One-way0 transfers
- 4:45 PM21h30Santo Domingo2:15 PMPanama City$3421One-way0 transfers
Live departures
Santo Domingo to Panama City flight times
The table below shows live departures for Santo Domingo to Panama City flights for tomorrow, Saturday, September 19. You can also manually refresh the results below to see updated flight journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| 4:45 PM Santo Domingo | 21h30 | 2:15 PM Panama City | 0 transfersDirect | |
This is the last flight of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Santo Domingo to Panama City by flight
Compare flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Sep 19
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Why should you book Santo Domingo to Panama City flights with Omio?
COPA Airlines as well as Avianca offer flights services from Santo Domingo to Panama City.
Omio is an official ticket reseller for all your travel options from Santo Domingo to Panama City.
Why book with Omio vs COPA Airlines?
- Compare with other providers: On Omio, you can not only buy tickets for COPA Airlines, but also compare tickets for the likes of Avianca to find the best option for your trip from Santo Domingo to Panama City.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
Why book with Omio over Skyscanner, Kayak or Trip?
- Compare with other providers: On Omio, you can also compare tickets for the likes of Avianca to find the best option for your trip from Santo Domingo to Panama City.
Airlines: Avianca, COPA Airlines from Santo Domingo to Panama CityFind the best flights between Santo Domingo to Panama City with Omio's travel partners Avianca, COPA Airlines from $320. We can find you the best deals, schedules and tickets when comparing and booking the best trip.
Avianca
About
Avianca is the national and largest airline of Colombia, and one of the oldest airlines in the world, tracing its origins back to 1919. It serves as the flagship of a group of airlines across the Americas, operating under a codesharing system. Avianca boasts an extensive network of destinations throughout the Americas, with its main hub located at El Dorado International Airport in Bogotá. The airline is a member of the Star Alliance, offering various classes of service from economy to business and first-class. Its fleet includes modern aircraft such as the Airbus A320 family, Airbus A330, and Boeing 787 Dreamliner.
Luggage & cancellation policy
Average Avianca Duration
4h 15m
Cheapest Avianca Price
$320
Avianca frequency
7 a day
Luggage included
1 carry-on bag (10kg) and 1 personal item included in most fares
Additional luggage
Additional checked baggage can be purchased, up to 32kg per piece
Cancellation Policy
Refunds available depending on fare type, some tickets non-refundable. Changes permitted with fee.
Pregnant on board
Pregnant women can travel up to 36 weeks for single pregnancies, 32 weeks for multiple pregnancies. Medical certificate required after 28 weeks
Unaccompagned minor
Children aged 5-17 can travel as unaccompanied minors with additional service fee. Must be booked at least 48 hours in advance
Amenities on board the airplane
Wifi
Food sold onboard
USB plugs
Accessibility
Assistance available for passengers with reduced mobility, must be requested 48h before flight
Pets
Small pets in cabin, max 8kg including carrier
Entertaiment on board
COPA Airlines
About
Copa Airlines, Panama's flag carrier, was founded in 1947 and is headquartered in Panama City with its main hub at Tocumen International Airport. The airline operates as a full-service carrier, connecting North, Central, and South America, as well as the Caribbean. As a member of the Star Alliance, Copa Airlines serves over 80 destinations in more than 30 countries. The airline's fleet primarily consists of Boeing 737 aircraft, with some Embraer 190s for regional flights. Copa Airlines is recognized for its punctuality and its strategic "Hub of the Americas" at Tocumen, which consolidates passenger traffic for efficient service.
Luggage & cancellation policy
Average COPA Airlines Duration
2h 32m
Cheapest COPA Airlines Price
$653
COPA Airlines frequency
5 a day
Luggage included
1 carry-on bag (22 x 14 x 9 inches) and 1 personal item
Additional luggage
Additional checked bags can be purchased, fees vary by route
Cancellation Policy
Refundable tickets available for full refund, non-refundable tickets can be changed for fee
Pregnant on board
Up to 36 weeks for single pregnancy, 32 weeks for multiple. Medical certificate required after 28 weeks
Unaccompagned minor
Ages 5-11 must use Unaccompanied Minor service. Ages 12-17 optional. Service fee applies
Amenities on board the airplane
Wifi
Food sold onboard
USB plugs
Accessibility
Wheelchair assistance available with 48-hour advance notice
Pets
Small pets in cabin, must be in approved carrier under seat
Entertaiment on board
Complete guide to Panama City
Things to do in Panama City
Discover the best of Panama City — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Panama City trip today.
- Must visit
Biomuseo
Modern museum by Frank Gehry exploring biodiversity, geology, and regional ecosystems through interactive exhibits on the Amador Causeway.
- Recommended
Museo de Arte Contemporáneo de Panamá
Contemporary art museum in Ancón with rotating exhibitions by Panamanian and international artists, plus a sculpture garden and canal views nearby.
- Must visit
Casco Antiguo
Atmospheric old quarter of plazas, churches, rooftops, and restored streets. Ideal for walking, architecture, and sunset views over the bay.
- Must visit
Cinta Costera
Long waterfront promenade popular for walking, cycling, skyline views, and breezes. A classic urban outing linking neighborhoods along the bay.
- Must visit
Amador Causeway
Scenic causeway built with canal excavation rock, known for bay views, marinas, bike rides, and easy access to museums and the cruise terminal area.
FAQs: Santo Domingo to Panama City Flight
Find answers to the most common questions about traveling from Santo Domingo to Panama City by flight. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest flight, the cheapest option, or tips for making the most of your visit at Panama City, this guide helps you travel smarter and with confidence.
Cheap plane tickets from Santo Domingo to Panama City can start from as little as $320 when you book in advance. The average flight ticket price for Santo Domingo to Panama City is $508 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by plane from Santo Domingo to Panama City is 2h 32m to travel the 916 miles (1475 km) long route. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest flight from Santo Domingo to Panama City leaves at 2:55 AM. Plan your trip with the Journey Planner from Omio.
The latest flight from Santo Domingo to Panama City leaves at 11:13 PM.
Yes, there are 5 direct flights a day from Santo Domingo to Panama City with COPA Airlines. Schedules can vary on holidays or weekends with fewer direct flights.
When taking a flight from Santo Domingo to Panama City, you can count on COPA Airlines, Avianca for the best way to get you to Panama City. You can also check all possible airlines who offer a service between Santo Domingo and Panama City and compare the amenities they offer before buying a plane ticket.
Flights from Santo Domingo to Panama City generally leave from Santo Domingo and arrive in Panama City.Santo Domingo is 3 miles (6 km) away from Santo Domingo city centre and Panama City is 0 miles (1 km) from Panama City city centre.
The cheapest month for a flight from Santo Domingo to Panama City is July.
Yes, you can take a flight between Santo Domingo and Panama City.
Since neither Santo Domingo nor Panama City are in the Schengen Area, passport requirements depend on the specific immigration rules of Dominican Republic and Panama. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
There is a time difference of 1 h between Santo Domingo and Panama City all year round.
The best events to attend in Panama City include:
- Carnaval de Panamá, a vibrant festival filled with parades, music, and dancing that celebrates the days leading up to Lent
- Festival de la Mejorana, a cultural event showcasing Panamanian folklore, music, and traditional crafts
- Panama Jazz Festival, an annual celebration of jazz featuring international artists and workshops for music enthusiasts.
The best holidays to experience in Panama City include:
- Carnival, vibrant street celebrations with colorful parades and lively music
- Independence Day, patriotic festivities with fireworks and cultural displays
- Labor Day, a chance to experience local traditions and community gatherings.
The best season to visit Panama City is Dry season or December to April. The best weather to explore Panama City is during December-April.
We recommend using the flight as it is the most popular way to get from Santo Domingo to Panama City among Omio's users.
For international flights we recommend to arrive 2.5 to 3 hours before departure. Please check the website of your departure airport if in doubt. Some airports may offer booking time slots for security checks or offer additional information on when to get there based on time of day.
Most airlines permit carry-on bags that fit within specific dimensions (e.g., 22 x 14 x 9 inches or 56 x 36 x 23 cm), including handles and wheels. Bags must fit in the overhead bin or under the seat in front of you.
Many airlines impose weight limits, commonly ranging between 7 kg (15 lbs) and 12 kg (26 lbs). Typically, passengers are allowed one carry-on bag and one personal item (for example a purse, laptop bag, or backpack). Personal items must fit under the seat in front of you. Budget Airlines (like Ryanair or Wizz Air) have stricter size and weight limits, often requiring fees for larger carry-ons. Full-Service Airlines have more lenient policies, sometimes including more spacious dimensions or higher weight limits depending on your ticket class.
The list of items prohibited on an airplane varies by country and airline, but in general, the following items are not allowed in carry-on or checked baggage: Weapons and self-defence items, sharp objects, flammable materials, explosives, toxic substances, or liquids over 100ml (except for medications and baby essentials). In checked baggage, firearms (without authorization), explosives, large lithium batteries, and hazardous chemicals are prohibited. Electronic cigarettes must be in carry-on bags, while alcohol and dry ice have restrictions. Always check with your airline for specific regulations.
Panama uses the Balboa (PAB) alongside the US Dollar (USD), which is widely accepted. For travelers, using cards is convenient in cities and tourist areas, but carrying some cash is recommended for smaller vendors and rural locations.
In Panama City, travelers should be cautious of petty theft, especially pickpocketing and bag snatching in crowded areas like Casco Viejo and public transportation. Avoid flashing valuables and be vigilant at ATMs to prevent card skimming. Scams involving unofficial taxi drivers overcharging or taking longer routes are common, so using authorized taxi services or ride-hailing apps is recommended. Additionally, travelers should stay aware of their surroundings at night and avoid poorly lit or isolated areas to ensure personal safety.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular airports
Popular airports from Santo Domingo to Panama City
Most Santo Domingo to Panama City flights use the Santo Domingo to Panama City airport pair. Use this guide to compare Santo Domingo and Panama City airports on this route, check city-centre transport, alongside checking practicalities like airport facilities and services.
Departure airports in Santo Domingo
Arrival airports in Panama City
Which Santo Domingo airport do flights to Panama City leave from?
Flights from Santo Domingo to Panama City depart from Santo Domingo. The airport is 4 miles (7 km) from Santo Domingo city centre at Ruta 66, Santo Domingo Este, Dominican Republic.
Santo Domingo (SDQ)Ruta 66, Santo Domingo Este, Dominican Republic
City-centre transport
Getting to Santo Domingo from Santo Domingo city centre
Santo Domingo is 6 km from Santo Domingo city centre. Public transport options include:
Bus OMSA, Route 40B, 30 km
Santo Domingo airport facilities and services
Santo Domingo has practical services for this route, including Wifi, Shopping, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Shower, Lounge, Lost and Found Office, and Car Rental.
Food and drink
Food options include: Several restaurants are available, including local cuisine and fast food options. Top choices include Café Santo Domingo and Pizza Hut.
Wi-Fi and ATMs
Free Wi-Fi available throughout the airport. ATMs are located in the arrivals and departures areas.
Luggage and lost property
Lost and found is available at the station.
Parking, taxis and toilets
Available at Santo Domingo: Parking, Taxis, WC.
Bike and car services
Available at Santo Domingo: Car Rental.
Accessibility
Accessibility facilities are available at Santo Domingo.
Shops, hotels and contact
Nearby hotels include Hotels are available within walking distance, including the Quality Hotel Real Aeropuerto Santo Domingo..
Which Panama City airport do flights from Santo Domingo arrive at?
Flights from Santo Domingo to Panama City arrive at Panama City. Panama City is 1 miles (2 km) from Panama City city centre.
Panama City (PTY)Tocumen Intertiol Airport, Avenida Domingo Díaz, Pama City, Pama
City-centre transport
Getting to Panama City from Panama City city centre
Panama City is 1 km from Panama City city centre. Public transport options include:
Metro Line 2, Estación Corredor Sur, 24 km
Panama City airport facilities and services
Panama City has practical services for this route, including Wifi, Shopping, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Shower, Lounge, Lost and Found Office, and Car Rental.
Food and drink
Food options include: Various restaurants in food court, including local cuisine and fast food
Wi-Fi and ATMs
Free Wi-Fi available throughout the airport. ATMs are located in all terminals.
Luggage and lost property
Lost and found is available at the station.
Parking, taxis and toilets
Available at Panama City: Parking, Taxis, WC.
Bike and car services
Available at Panama City: Car Rental.
Accessibility
Accessibility facilities are available at Panama City: Elevators, ramps.
Shops, hotels and contact
Nearby hotels include Hotels nearby, such as Crowne Plaza Pama Airport..
Most popular flights from Santo Domingo
More options for your journey from Santo Domingo to Panama City
Here are some other resources that might have the information you need
Most popular flights to and from Panama City and Santo Domingo
Most popular flights to Panama City
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