- Recommended
Greenville County Museum of Art
A major art museum in downtown Greenville with American art, Southern works, and rotating exhibitions in a bright riverfront setting.
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Journey information
Overview: Pittsburgh, PA to Greenville, SC flight
USAUSA
Flights from Pittsburgh, PA to Greenville, SC depart on average 45 times per day, taking around 3h 55m. Cheap flight tickets for this journey start at €273 but you can travel from only €81 by bus.
The earliest flight runs at 05:00, the last at 20:21. The fastest flight covers the 407 miles (656 km) distance in 2h 28m. March is the cheapest month to fly.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from €81
Distance 407 miles (656 km) |
Average flight duration 3h 55m |
Cheapest ticket price €273 |
Flights per day 45 |
Fastest flight 2h 28m |
First flight 5:00 AM |
Last flight 8:21 PM |
Cheapest Month Mar |
Cheapest Day Tue |
High Season Jul - Sep |
Low Season Oct - Dec |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from €81
Travel Information
Compare bus and train for Pittsburgh, PA to Greenville, SC
Omio recommends booking the flight as it is the most popular option from Pittsburgh, PA to Greenville, SC among Omio's users. If you are prioritising price, take the bus, with an average ticket price of €120 For those with little time, consider booking a flight, which has an average total journey time of 5h 55m. Average ticket prices depend on the travel mode: a bus costs an average of €120, while a flight costs an average of €600.
Distance: 407 miles (656 km)
Compare flight with
Most popular Flight | Train | Bus |
|---|---|---|
€600 Average price | €245 Average price | €120 Average price Cheapest |
5h 55m Average total duration Fastest 3h 55m Onboard + 2h 0m Additional time* | 20h 27m Average total duration 19h 57m Onboard + 30m Additional time* | 18h 44m Average total duration 18h 14m Onboard + 30m Additional time* |
 Most popular airline |  Most popular train company |  Most popular bus company |
Direct Options | Direct Options | Direct Options |
The cheapest way to travel from Pittsburgh, PA to Greenville, SC is a bus with an average price of €120.
This is compared to other travel options from Pittsburgh, PA to Greenville, SC:
A bus is €126 less than a train for this route with tickets for a train from Pittsburgh, PA to Greenville, SC costing on average €245.
A bus is €480 less than a flight for this route with tickets for a flight from Pittsburgh, PA to Greenville, SC costing on average €600.
The fastest way to travel from Pittsburgh, PA to Greenville, SC is by flight with an average journey time of 3h 55m.
Other travel options to Greenville, SC take longer:
Bus takes on average 18h 14m.
Train takes on average 19h 57m.
It's helpful to compare your options as there are 2 ways to travel between Pittsburgh, PA and Greenville, SC including taking a bus and train.
We recommend using the flight as it is the most popular way to get from Pittsburgh, PA to Greenville, SC among Omio's users.
Compare prices and tickets Pittsburgh, PA to Greenville, SC by bus or train
Compare bus and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Pittsburgh, PA to Greenville, SC flights with Omio?
American Airlines as well as Republic Airlines, United, psa airlines and more offer flights services from Pittsburgh, PA to Greenville, SC.
Omio is an official ticket reseller for all your travel options from Pittsburgh, PA to Greenville, SC.
Why book with Omio vs American Airlines?
- Compare with other providers: On Omio, you can not only buy tickets for American Airlines, but also compare tickets for the likes of Republic Airlines, United or psa airlines to find the best option for your trip from Pittsburgh, PA to Greenville, SC.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare American Airlines with all available travel options, which are bus and train to ensure you get the best deal for traveling from Pittsburgh, PA to Greenville, SC.
Why book with Omio over Trip, Edreams or Skyscanner?
- Compare with other providers: On Omio, you can also compare tickets for the likes of Republic Airlines, United or psa airlines to find the best option for your trip from Pittsburgh, PA to Greenville, SC.
- Multiple modes of transport: Omio allows you to compare travel options including bus and train to find the ideal travel option from Pittsburgh, PA to Greenville, SC.
Airlines: American Airlines, United, Republic Airlines, psa airlines from Pittsburgh, PA to Greenville, SCFind the best flights between Pittsburgh, PA to Greenville, SC with Omio's travel partners American Airlines, United, Republic Airlines, psa airlines from €81. We can find you the best deals, schedules and tickets when comparing and booking the best trip.
United
About
United Airlines, established in 1926, is a major U.S. airline headquartered in Chicago, Illinois. Operating an extensive domestic and international network, United serves more destinations than any other airline, connecting travelers across six continents. The airline's eight hubs include Chicago–O'Hare, Denver, Houston–Intercontinental, Los Angeles, Newark, San Francisco, Washington–Dulles, and Guam. As a founding member of the Star Alliance, United offers a comprehensive range of services, including regional flights through United Express, catering to both leisure and business travelers. The airline is committed to sustainability, investing in sustainable aviation fuel and innovative technologies to reduce its environmental impact.
Luggage & cancellation policy
Average United Duration
3h 3m
Cheapest United Price
€273
United frequency
20 a day
Luggage included
Carry-on baggage allowance is 7kg total (2 pieces max. ) for both Choice and Flex fares on United Airlines and Virgin Australia flights.
Additional luggage
Excess baggage fees apply for additional checked luggage beyond the standard allowance.
Luggage storage
Both airlines provide checked baggage services for storing luggage during flights.
Cancellation Policy
Cancellation fees apply per person, per booking, with specific fees for different fare types.
Refund
Not applicable to flights; however, full refunds are available if flights are canceled by the airline.
Pregnant on board
Pregnant passengers are permitted to travel, with specific guidelines and medical certificates required after a certain gestational period.
Unaccompagned minor
Unaccompanied minors are permitted to travel, with specific age restrictions and services provided.
Amenities on board the airplane
Wifi
Food sold onboard
Meals and snacks are included on international flights operated by United Airlines and Virgin Australia.
Seat reservation
Seat selection may incur additional fees, depending on the fare type and airline.
Toilets
USB plugs
Accessibility
United Airlines and Virgin Australia offer services to and within Australia, providing accessible travel options for passengers with mobility needs.
Bikes
Both airlines permit bicycles onboard, with specific guidelines and fees.
Pets
United Airlines and Virgin Australia allow pets onboard, subject to specific policies and fees.
American Airlines
About
American Airlines is one of the largest airlines in the world, connecting travelers to hundreds of destinations across the United States, Latin America, Europe, Asia, and beyond. Operating from major hubs such as Dallas/Fort Worth, Miami, and Charlotte, American offers a wide range of travel options. Passengers can choose from Economy with affordable fares, Premium Economy with extra space, or Business and First Class featuring flat-bed seats, premium dining, and lounge access. With a modern fleet and membership in the oneworld alliance, American Airlines combines global reach with comfort and reliability.
Luggage & cancellation policy
Average American Airlines Duration
2h 28m
Cheapest American Airlines Price
€311
American Airlines frequency
20 a day
Luggage included
1 carry-on bag (22 x 14 x 9 inches) and 1 personal item (18 x 14 x 8 inches) included in most fares
Additional luggage
Checked bags fees vary by route. First checked bag typically $30, second $40 on domestic flights
Cancellation Policy
Basic Economy tickets cannot be changed or refunded. Other fares allow changes with fee, refunds subject to fare rules.
Pregnant on board
Passengers can fly up to 36 weeks for single pregnancies, 32 weeks for multiple pregnancies. Medical certificate required within 7 days of departure if within 4 weeks of due date.
Unaccompagned minor
Children ages 5-14 can travel alone using American Airlines Unaccompanied Minor Service. Service fee is $150 each way.
Amenities on board the airplane
Wifi
Food sold onboard
USB plugs
Accessibility
American Airlines provides wheelchair assistance and special services for passengers with disabilities. Assistance must be requested at least 48 hours before departure.
Pets
Small dogs and cats allowed in cabin for $125 fee. Must be in approved carrier under seat. Service animals allowed.
psa airlines
About
PSA Airlines is an American regional airline and a wholly-owned subsidiary of the American Airlines Group, operating exclusively on behalf of American Airlines under the American Eagle brand. Headquartered in Charlotte, North Carolina, PSA Airlines operates over 800 daily flights to nearly 100 destinations across the United States. The airline maintains an all-jet fleet consisting of Bombardier CRJ700 and CRJ900 regional aircraft. With a team of over 5,000 employees, PSA Airlines plays a significant role in connecting smaller cities to major hubs within American Airlines' network.
Luggage & cancellation policy
Average psa airlines Duration
3h 19m
Cheapest psa airlines Price
€681
psa airlines frequency
2 a day
Luggage included
One carry-on bag and one personal item are allowed.
Additional luggage
Additional luggage can be checked for a fee, with weight limits up to 32kg (70lbs) for a single piece.
Cancellation Policy
PSA Airlines' cancellation policy depends on the timeframe of cancellation and ticket flexibility, with some flexible ticket options offering easier cancellations.
Refund
Passengers are entitled to a refund if the airline cancels a flight and they choose not to travel.
Amenities on board the airplane
Food sold onboard
Non-alcoholic beverages are complimentary in Economy Class, while alcoholic drinks and snack boxes can be purchased.
Seat reservation
Seat selection for standard seating is typically included, but preferred or Main Cabin Extra seats may require an additional fee.
Accessibility
Wheelchair assistance is available and should be requested at least 24 hours prior to flight departure.
Bikes
Bicycles can be carried as checked baggage if handlebars are turned sideways, pedals are removed, tires are deflated, and the bike is packed in a case or durable cardboard box.
Republic Airlines
About
Republic Airways is a major regional airline in the United States, operating as a subsidiary of Republic Airways Holdings. It provides scheduled passenger service for American Airlines (as American Eagle), Delta Air Lines (as Delta Connection), and United Airlines (as United Express) using a fleet of Embraer 170 and 175 regional jets. Headquartered in Indianapolis, Indiana, Republic Airways operates over 900 daily flights to more than 80 cities across the U.S. and Canada. The company is known for its large fleet of Embraer E-Jets and its state-of-the-art training facilities. In April 2025, Republic Airways Holdings announced its acquisition of Mesa Air Group, which is expected to create the second-largest regional carrier in the U.S.
Luggage & cancellation policy
Average Republic Airlines Duration
3h 46m
Cheapest Republic Airlines Price
€555
Republic Airlines frequency
3 a day
Luggage included
One carry-on bag (24 x 16 x 10) and one personal item
Additional luggage
Checked bags for a fee
Cancellation Policy
Tickets are non-refundable but may be cancelled for future flight credit minus applicable fees
Pregnant on board
Passengers can fly up to the end of their 36th week for single pregnancies and the end of their 32nd week for multiple pregnancies
Unaccompagned minor
Unaccompanied minor service is available for children ages 5-14. Must be booked directly with Republic Airlines
Amenities on board the airplane
USB plugs
Accessibility
Republic Airlines offers assistance for passengers with reduced mobility, including wheelchair services and priority boarding. Passengers are advised to request these services in advance to ensure availability and proper arrangements.
Complete guide to Greenville, SC
Things to do in Greenville, SC
Discover the best of Greenville, SC — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Greenville, SC trip today.
Greenville Center for Creative Arts
A contemporary art center showing regional and international artists through rotating exhibitions in a modern downtown gallery space.
Metropolitan Arts Council Gallery
A local gallery and arts space featuring exhibitions, classes, and community-focused programming in Greenville's Village area.
- Must visit
Falls Park on the Reedy
A signature downtown park with waterfalls, gardens, river trails, and lawns. It is Greenville's most popular public space for walking and views.
- Must visit
Main Street
Greenville's central street lined with shops, public art, and historic buildings. It is ideal for strolling between downtown attractions.
- Recommended
Prisma Health Swamp Rabbit Trail
A swamp rabbit-themed riverside greenway popular for walking and cycling, linking downtown Greenville with parks and nearby districts.
FAQs: Pittsburgh, PA to Greenville, SC Flight
Find answers to the most common questions about traveling from Pittsburgh, PA to Greenville, SC by flight. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest flight, the cheapest option, or tips for making the most of your visit at Greenville, SC, this guide helps you travel smarter and with confidence.
Cheap plane tickets from Pittsburgh, PA to Greenville, SC can start from as little as €273 when you book in advance. The average flight ticket price for Pittsburgh, PA to Greenville, SC is €600 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by plane from Pittsburgh, PA to Greenville, SC is 2h 28m to travel the 407 miles (656 km) long route. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest flight from Pittsburgh, PA to Greenville, SC leaves at 5:00 AM. Plan your trip with the Journey Planner from Omio.
The latest flight from Pittsburgh, PA to Greenville, SC leaves at 8:21 PM.
There are 45 flights a day from Pittsburgh, PA to Greenville, SC which require at least one change with American Airlines, Republic Airlines, United, psa airlines. Schedules can vary on holidays or weekends with fewer flights.
When taking a flight from Pittsburgh, PA to Greenville, SC, you can count on American Airlines, Republic Airlines, United, psa airlines for the best way to get you to Greenville, SC. You can also check all possible airlines who offer a service between Pittsburgh, PA and Greenville, SC and compare the amenities they offer before buying a plane ticket.
Flights from Pittsburgh, PA to Greenville, SC generally leave from Pittsburgh International Airport and arrive in Greenville-Spartanburg International Airport.Pittsburgh International Airport is 2 miles (4 km) away from Pittsburgh, PA city centre and Greenville-Spartanburg International Airport is 3 miles (5 km) from Greenville, SC city centre.
The cheapest month for a flight from Pittsburgh, PA to Greenville, SC is March.
It's helpful to compare your options as there are 2 ways to travel between Pittsburgh, PA and Greenville, SC including taking a bus and train.
Since neither Pittsburgh, PA nor Greenville, SC are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
There is no time difference between Pittsburgh, PA and Greenville, SC.
The best events to attend in Greenville, SC include:
- Greenville Jazz Festival, a vibrant celebration of jazz music featuring local and national artists performing in various venues
- Artisphere, an annual arts festival showcasing visual arts, live performances, and culinary delights from regional artists
- Fall for Greenville, a food and music festival highlighting the best local cuisine and entertainment in a family-friendly atmosphere.
The best holidays to experience in Greenville, SC include:
- Memorial Day, the unofficial start of summer with vibrant local events and parades
- Independence Day, spectacular fireworks and festive celebrations throughout the city
- Labor Day, a perfect time for outdoor activities and community gatherings as summer winds down.
The best season to visit Greenville, SC is Spring or Fall. The best weather to explore Greenville, SC is during April-May or September-October.
We recommend using the flight as it is the most popular way to get from Pittsburgh, PA to Greenville, SC among Omio's users.
For domestic flights we recommend to arrive 1.5 to 2 hours before departure. Please check the website of your departure airport if in doubt. Some airports may offer booking time slots for security checks or offer additional information on when to get there based on time of day.
Most airlines permit carry-on bags that fit within specific dimensions (e.g., 22 x 14 x 9 inches or 56 x 36 x 23 cm), including handles and wheels. Bags must fit in the overhead bin or under the seat in front of you.
Many airlines impose weight limits, commonly ranging between 7 kg (15 lbs) and 12 kg (26 lbs). Typically, passengers are allowed one carry-on bag and one personal item (for example a purse, laptop bag, or backpack). Personal items must fit under the seat in front of you. Budget Airlines (like Ryanair or Wizz Air) have stricter size and weight limits, often requiring fees for larger carry-ons. Full-Service Airlines have more lenient policies, sometimes including more spacious dimensions or higher weight limits depending on your ticket class.
The list of items prohibited on an airplane varies by country and airline, but in general, the following items are not allowed in carry-on or checked baggage: Weapons and self-defence items, sharp objects, flammable materials, explosives, toxic substances, or liquids over 100ml (except for medications and baby essentials). In checked baggage, firearms (without authorization), explosives, large lithium batteries, and hazardous chemicals are prohibited. Electronic cigarettes must be in carry-on bags, while alcohol and dry ice have restrictions. Always check with your airline for specific regulations.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Greenville, SC, travelers should be cautious of pickpocketing and petty theft, especially in crowded areas like downtown and popular events. Common scams include overcharging by unofficial taxi or ride-share drivers and fake charity solicitations. It is advisable to use authorized transportation services, avoid displaying valuables openly, and stay aware of surroundings, particularly at night.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular airports
Popular airports from Pittsburgh, PA to Greenville, SC
Most Pittsburgh, PA to Greenville, SC flights use the Pittsburgh International Airport to Greenville-Spartanburg International Airport airport pair. Use this guide to compare Pittsburgh, PA and Greenville, SC airports on this route, check city-centre transport, alongside checking practicalities like airport facilities and services.
Departure airports in Pittsburgh
Arrival airports in Greenville
Which Pittsburgh, PA airport do flights to Greenville, SC leave from?
Flights from Pittsburgh, PA to Greenville, SC depart from Pittsburgh International Airport. The airport is 2 miles (4 km) from Pittsburgh, PA city centre at 1000 Airport Blvd, Pittsburgh, PA 15231, USA.
Pittsburgh International Airport (PIT)1000 Airport Blvd, Pittsburgh, PA 15231, USA
City-centre transport
Getting to Pittsburgh International Airport from Pittsburgh city centre
Pittsburgh International Airport is 4 km from Pittsburgh city centre. Public transport options include:
BusRt 29 · 30m · €28
28X · 48m · every ~4 min
Pittsburgh International Airport airport facilities and services
Pittsburgh International Airport has practical services for this route, including Wifi, Shopping, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Shower, Lounge, Lost and Found Office, and Car Rental.
Food and drink
Food options include: Various restaurants are located in the Airside terminal, including fast food and sit-down options like Chick-fil-A and The Burgh Sportz Bar.
Wi-Fi and ATMs
Free Wi-Fi available throughout the airport. ATMs are located throughout the airport, including near the baggage claim and in the Airside terminal.
Luggage and lost property
Lost and found is available at the station.
Parking, taxis and toilets
Available at Pittsburgh International Airport: Parking, Taxis, WC.
Bike and car services
Available at Pittsburgh International Airport: Car Rental.
Accessibility
Accessibility facilities are available at Pittsburgh International Airport: Elevators, ramps.
Shops, hotels and contact
Nearby hotels include Hotels like Hyatt Regency Pittsburgh Intertiol Airport are connected to the terminal..
Which Greenville, SC airport do flights from Pittsburgh, PA arrive at?
Flights from Pittsburgh, PA to Greenville, SC arrive at Greenville-Spartanburg International Airport. Greenville-Spartanburg International Airport is 3 miles (5 km) from Greenville, SC city centre.
Greenville-Spartanburg International Airport (GSP)Greenville-Spartanburg International Airport (GSP), 2000 GSP Dr, Greer, SC 29651, USA
City-centre transport
Getting to Greenville-Spartanburg International Airport from Greenville city centre
Greenville-Spartanburg International Airport is 5 km from Greenville city centre. Public transport options include:
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Greenville-Spartanburg International Airport airport facilities and services
Greenville-Spartanburg International Airport has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Several dining options are available in the terminal.
Wi-Fi and ATMs
Free Wi-Fi available throughout the terminal. ATMs are aTMs available near baggage claim.
Tickets and information
Ticket office support is available at Greenville-Spartanburg International Airport.
Parking, taxis and toilets
Available at Greenville-Spartanburg International Airport: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Greenville-Spartanburg International Airport: Elevators and ramps available for accessibility.
Most popular flights from Pittsburgh, PA
More options for your journey from Pittsburgh, PA to Greenville, SC
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Most popular flights to and from Greenville, SC and Pittsburgh, PA
Most popular flights to Greenville, SC
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