Journey information
Overview: Pittsburgh, PA to Greenville, SC flight
Flights from Pittsburgh, PA to Greenville, SC depart on average 61 times per day, taking around 2h 58m. Cheap flight tickets for this journey start at $108 (€88) if you book in advance.
There are 1 flights per day. The earliest flight runs at 05:00, the last at 20:10. The fastest flight covers the 407 miles (656 km) distance in 1h 37m. November is the cheapest month to fly.
Distance 407 miles (656 km) |
Average flight duration 2h 58m |
Cheapest ticket price $108 (€88) |
Flights per day 61 |
Direct flights 1 |
Fastest flight 1h 37m |
Cheapest month November |
First flight 05:00 |
Last flight 20:10 |
The cheapest and fastest flights from Pittsburgh, PA to Greenville, SC
Cheapest price
$266
Average price
$266
Fastest journey
5 h 41 m
Average duration
5 h 41 m
Flights per day
1
Distance
656 km
The best way to find a cheap flight ticket from Pittsburgh, PA to Greenville, SC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Pittsburgh, PA to Greenville, SC will cost around $266 if you buy it on the day, but the cheapest tickets can be found for only $266.
Of the 1 flights that leave Pittsburgh, PA for Greenville, SC onMon, Mar 23, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Mon, Mar 23 the direct flights cover the 656 km distance in an average of 5 h 41 m but if you time it right, some flights will get you there in just 5 h 41 m .
On Mon, Mar 23 the longest flights will take 5 h 41 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Travel Information
Compare bus, train, and flight for Pittsburgh, PA to Greenville, SC
Omio recommends booking the bus as it is the most popular option from Pittsburgh, PA to Greenville, SC among Omio's users. If you are prioritising price take the bus with prices starting from $146. For those with little time consider booking a flight which can get you there in 2h 58m. The ticket price range depends on the travel mode: a bus costs an average of $146, and a train costs an average of $207.
Distance: 407 miles (656 km)
Compare flight with
| Flight | Most popular Bus | Train |
|---|---|---|
$194 Average price | $182 Average price Cheapest | $526 Average price |
5h 58m Average total duration Fastest 2h 58m Onboard + 3h 0m Additional time* | 23h 20m Average total duration 22h 50m Onboard + 30m Additional time* | 23h 47m Average total duration 23h 17m Onboard + 30m Additional time* |
Direct Options | Direct Options | Direct Options |
Compare prices and tickets Pittsburgh, PA to Greenville, SC by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Mar 29
FAQs: Pittsburgh, PA to Greenville, SC Flight
Find answers to the most common questions about traveling from Pittsburgh, PA to Greenville, SC by flight. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest flight, the cheapest option, or tips for making the most of your visit at Greenville, SC, this guide helps you travel smarter and with confidence.

- Greenville Jazz Festival, a vibrant celebration of jazz music featuring local and national artists performing in various venues
- Artisphere, an annual arts festival showcasing visual arts, live performances, and culinary delights from regional artists
- Fall for Greenville, a food and music festival highlighting the best local cuisine and entertainment in a family-friendly atmosphere.
- Memorial Day, the unofficial start of summer with vibrant local events and parades
- Independence Day, spectacular fireworks and festive celebrations throughout the city
- Labor Day, a perfect time for outdoor activities and community gatherings as summer winds down.
popular airports
Popular airports from Pittsburgh, PA to Greenville, SC
- Free Wi-Fi available throughout the airport.
- Shops are located in the Airside terminal, including Duty-Free and Hudson News.
- Parking available at terminal 1 and terminal 2, approximately 1.9€ (BRL 10) per hour.
- Various restaurants are located in the Airside terminal, including fast food and sit-down options like Chick-fil-A and The Burgh Sportz Bar.
- Available outside the terminal.
- Elevators, ramps
- Available throughout the airport, in both terminals.
- Hotels like Hyatt Regency Pittsburgh Intertiol Airport are connected to the terminal.
- Showers are available in the airport lounges; access may require a lounge pass or membership.
- Lounges available, including The Club Lounge, which offers amenities for a fee or membership.
- Lost and Found located in the Landside terminal; inquiries can be made at the airport information desk.
- Car rental services are available on-site, with companies like Hertz and Enterprise.
- 28X Airport Flyer bus, stop at Pittsburgh Intertiol Airport, 45 minutes to city center
Most popular flights from Pittsburgh, PA
More options for your journey from Pittsburgh, PA to Greenville, SC
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