- Must visit
Art Institute of Chicago
World-class art museum with masterpieces from Monet to Hopper and the famous Modern Wing.
Cheapest price on Oct 07
$45
Average ticket price on Oct 07
$46
Fastest journey on Oct 07
5 h
Average journey duration on Oct 07
5 h 25 m
Buses on Oct 07
2
Distance
336 km
The best way to find a cheap bus ticket from Ypsilanti, MI to Chicago, IL is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Ypsilanti, MI to Chicago, IL will cost around $46 if you buy it on the day, but the cheapest tickets can be found for only $45.
On Wed, Oct 07, we found 2 buses from Ypsilanti, MI to Chicago, IL, including 2 direct services.
On Wed, Oct 07 the direct buses cover the 336 km distance in an average of 5 h 25 m but if you time it right, some buses will get you there in just 5 h .
On Wed, Oct 07 the slowest buses will take 5 h 50 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.




Buses from Ypsilanti, MI to Chicago, IL run on average 4 times per day, taking around 5h 12m. Cheap bus tickets for this journey start at $45 (€38) if you book in advance.
There are 4 buses per day. The earliest bus runs at 00:35, the last at 23:35. The fastest bus covers the 208 miles (336 km) distance in 3h 55m.
Distance 208 miles (336 km) |
Average bus duration 5h 12m |
Cheapest ticket price $45 (€38) |
Buses per day 4 |
Direct buses 4 |
Fastest bus 3h 55m |
First bus 12:35 AM |
Last bus 11:35 PM |
Cheapest Month Jan |
Cheapest Day Mon |
High Season Apr - Jun |
Low Season Jul - Sep |
Busiest Day Wed |
Least Busy Day Wed |
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 12:35AM | Arrival Time 05:25AM | Duration 5h50 | Departure days Wed, Thu | Cheapest price $45 |
Operator Greyhound | Departure Time 05:35AM | Arrival Time 11:25AM | Duration 5h50 | Departure days Fri | Cheapest price $41 |
Operator FlixBus | Departure Time 12:15PM | Arrival Time 04:25PM | Duration 4h10 | Departure days Sun | Cheapest price $49 |
Operator FlixBus | Departure Time 01:15PM | Arrival Time 05:25PM | Duration 4h10 | Departure days Fri | Cheapest price $67 |
Operator Amtrak | Departure Time 02:23PM | Arrival Time 07:02PM | Duration 4h39 | Departure days Mon | Cheapest price $42 |
Operator The Ride Ann Arbor | Departure Time 03:53PM | Arrival Time 09:25PM | Duration 5h32 | Departure days Tue | Cheapest price $63 |
Operator Greyhound | Departure Time 05:25PM | Arrival Time 09:25PM | Duration 5h00 | Departure days Wed, Thu | Cheapest price $47 |
Operator Greyhound | Departure Time 09:25PM | Arrival Time 02:25AM | Duration 5h00 | Departure days Sat | Cheapest price $59 |
Operator Greyhound | Departure Time 10:25PM | Arrival Time 03:25AM | Duration 5h00 | Departure days Fri | Cheapest price $47 |
Operator The Ride Ann Arbor | Departure Time 10:30PM | Arrival Time 05:25AM | Duration 6h55 | Departure days Tue | Cheapest price $63 |
The table below shows live departures for Ypsilanti, MI to Chicago, IL buses for today, Tuesday, October 6. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 3:53 PM Ypsilanti, MI | 5h32 | 9:25 PM Chicago, IL | 2 transfers | |
![]() | 10:30 PM Ypsilanti, MI | 6h55 | 5:25 AM Chicago, IL | 2 transfers | |
| Wednesday, October 7 | |||||
![]() | 12:35 AM Ann Arbor, Amtrak Station | 5h50 | 5:25 AM Chicago, Greyhound Bus Station | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Discover the best of Chicago, IL — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Chicago, IL trip today.
World-class art museum with masterpieces from Monet to Hopper and the famous Modern Wing.
Major natural history museum with Sue the T. rex, ancient cultures, and strong family appeal.
Hands-on science museum in a grand former fair building, popular for exhibits and a U-505 submarine.
Lively lakefront park with Cloud Gate, Crown Fountain, gardens, and major public art in central Chicago.
Famous shopping boulevard lined with architecture, hotels, riverfront views, and major city energy.
Scenic pedestrian-friendly riverwalk with boat docks, public art, bridges, and standout skyline perspectives.
Deep-dish pizza is Chicago’s iconic pie with a tall buttery crust, layers of cheese and toppings, and chunky tomato sauce baked on top.
The Chicago-style hot dog is an all-beef frank on a poppy seed bun with mustard, relish, onion, tomato, pickle, peppers, and celery salt.
Italian beef is thin-sliced roast beef piled onto a roll, often dipped in savory juices and topped with sweet peppers or spicy giardiniera.
Classic spot for juicy Italian beef sandwiches, especially dipped and topped with spicy giardiniera, with a casual local feel.
Legendary stand for Chicago-style hot dogs and char-grilled sausages, served fast in a no-frills local landmark.
World-famous fine dining destination offering a highly creative tasting menu and refined service in an elegant setting.
Moderate for a major US city: hotels can be pricey, but transit is affordable and dining ranges from cheap eats to upscale options.
Tip 18-20% at restaurants, $1-2 per drink at bars, 10-15% for taxis, and optional small change at cafes.
Find answers to the most common questions about traveling from Ypsilanti, MI to Chicago, IL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Chicago, IL, this guide helps you travel smarter and with confidence.

Most Ypsilanti, MI to Chicago, IL buses use the Ann Arbor, Amtrak Station to Chicago, Greyhound Bus Station station pair. Use this guide to compare Ypsilanti, MI and Chicago, IL bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Chicago, Greyhound Bus Station is 2 km from Chicago city centre. Public transport options include:
Chicago, Greyhound Bus Station has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Snack shop and vending machines available
Free Wi-Fi in waiting area. ATMs are located near entrance.
Ticket office support is available at Chicago, Greyhound Bus Station.
Available at Chicago, Greyhound Bus Station: Parking, Taxis, WC.
Accessibility facilities are available at Chicago, Greyhound Bus Station: Wheelchair accessible entrances and seating.
Here are some other resources that might have the information you need