The cheapest and fastest buses from Ypsilanti, MI to Chicago, IL
Cheapest price
$42
Average price
$43
Fastest journey
4 h 10 m
Average duration
5 h 15 m
Buses per day
4
Distance
336 km
The best way to find a cheap bus ticket from Ypsilanti, MI to Chicago, IL is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Ypsilanti, MI to Chicago, IL will cost around $43 if you buy it on the day, but the cheapest tickets can be found for only $42.
Of the 4 buses that leave Ypsilanti, MI for Chicago, IL on Tue, May 19, 4 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Tue, May 19 the direct buses cover the 336 km distance in an average of 5 h 15 m but if you time it right, some buses will get you there in just 4 h 10 m .
On Tue, May 19 the slowest buses will take 6 h and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
12:35 AM5h50Ann Arbor, Amtrak Station5:25 AMChicago, Greyhound Bus Station$421One-way0 transfers
5:25 PM5h00Ann Arbor, Amtrak Station9:25 PMChicago, Greyhound Bus Station$431One-way0 transfers
9:20 AM6h00Ann Arbor, Amtrak Station2:20 PMChicago, Greyhound Bus Station$431One-way0 transfers
FlixBus8:15 AM4h10Ann Arbor, Amtrak Station11:25 AMChicago, Greyhound Bus Station$451One-way0 transfers
FlixBus8:15 AM4h10Ann Arbor, Amtrak Station11:25 AMChicago, Greyhound Bus Station$451One-way0 transfers
5:25 PM5h00Ann Arbor, Amtrak Station9:25 PMChicago, Greyhound Bus Station$431One-way0 transfers
12:35 AM5h50Ann Arbor, Amtrak Station5:25 AMChicago, Greyhound Bus Station$421One-way0 transfers
9:20 AM6h00Ann Arbor, Amtrak Station2:20 PMChicago, Greyhound Bus Station$431One-way0 transfers
Travel Information
Compare bus, train, and flight for Ypsilanti, MI to Chicago, IL
Omio recommends booking the train as it is the most popular option from Ypsilanti, MI to Chicago, IL among Omio's users. If you are prioritising price take the bus with prices starting from $43. For those with little time consider booking a flight which can get you there in 1h 34m. The ticket price range depends on the travel mode: a bus costs an average of $43, and a flight costs an average of $338.
Distance: 208 miles (336 km)
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
$58 Average price Cheapest | $75 Average price | $395 Average price |
5h 3m Average total duration 4h 33m Onboard + 30m Additional time* | 5h 15m Average total duration 4h 45m Onboard + 30m Additional time* | 4h 34m Average total duration Fastest 1h 34m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Ypsilanti, MI to Chicago, IL:
A bus is $18 (€14) less than a train for this route with tickets for a train from Ypsilanti, MI to Chicago, IL costing on average $75 (€61).
A bus is $337 (€272) less than a flight for this route with tickets for a flight from Ypsilanti, MI to Chicago, IL costing on average $395 (€319).
Other travel options to Chicago, IL take longer:
Bus takes on average 4h 33m.
Train takes on average 4h 45m.
Ypsilanti, MI to Chicago, IL Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 12:35AM | Arrival Time 05:25AM | Duration 5h50 | Departure days Tue | Cheapest price $42 |
Operator Greyhound | Departure Time 05:35AM | Arrival Time 11:25AM | Duration 5h50 | Departure days Fri | Cheapest price $43 |
Operator FlixBus | Departure Time 08:15AM | Arrival Time 11:25AM | Duration 4h10 | Departure days Tue | Cheapest price $45 |
Operator Greyhound | Departure Time 09:20AM | Arrival Time 02:20PM | Duration 6h00 | Departure days Tue | Cheapest price $43 |
Operator FlixBus | Departure Time 12:15PM | Arrival Time 04:25PM | Duration 4h10 | Departure days Sun | Cheapest price $51 |
Operator FlixBus | Departure Time 01:15PM | Arrival Time 05:25PM | Duration 4h10 | Departure days Fri | Cheapest price $69 |
Operator Amtrak | Departure Time 02:23PM | Arrival Time 07:02PM | Duration 4h39 | Departure days Mon, Thu | Cheapest price $44 |
Operator Greyhound | Departure Time 05:25PM | Arrival Time 09:25PM | Duration 5h00 | Departure days Tue | Cheapest price $43 |
Operator Greyhound | Departure Time 09:25PM | Arrival Time 02:25AM | Duration 5h00 | Departure days Wed, Sat | Cheapest price $62 |
Operator Greyhound | Departure Time 10:25PM | Arrival Time 03:25AM | Duration 5h00 | Departure days Wed, Thu, Fri | Cheapest price $48 |
Live departures
Ypsilanti, MI to Chicago, IL bus times
The table below shows live departures for Ypsilanti, MI to Chicago, IL buses for today, Monday, May 18. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 2:23 PM Ypsilanti, MI | 4h39 | 7:02 PM Chicago, IL | 0 transfersDirect | |
| Tuesday, May 19 | |||||
![]() | 12:35 AM Ann Arbor, Amtrak Station | 5h50 | 5:25 AM Chicago, Greyhound Bus Station | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Ypsilanti, MI to Chicago, IL by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
May 19
May 20
May 21
May 22
May 23
May 24
May 25
Why should you book Ypsilanti, MI to Chicago, IL buses with Omio?
Why book with Omio vs Greyhound?
- Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of FlixBus or The Ride Ann Arbor to find the best option for your trip from Ypsilanti, MI to Chicago, IL.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Ypsilanti, MI to Chicago, IL.
Why book with Omio over Wanderu or Trainline?
- Compare with other providers: On Omio, you can also compare tickets for the likes of FlixBus or The Ride Ann Arbor to find the best option for your trip from Ypsilanti, MI to Chicago, IL.
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Ypsilanti, MI to Chicago, IL.
Journey information
Overview: Bus from Ypsilanti, MI to Chicago, IL
Buses from Ypsilanti, MI to Chicago, IL run on average 4 times per day, taking around 4h 33m. Cheap bus tickets for this journey start at $43 (€35) if you book in advance.
There are 3 buses per day. The earliest bus runs at 00:35, the last at 23:35. The fastest bus covers the 208 miles (336 km) distance in 4h 10m.
Distance 208 miles (336 km) |
Average bus duration 4h 33m |
Cheapest ticket price $43 (€35) |
Buses per day 4 |
Direct buses 3 |
Fastest bus 4h 10m |
First bus 12:35 AM |
Last bus 11:35 PM |
Cheapest Month Aug |
Cheapest Day Mon |
High Season Apr - Jun |
Low Season Jul - Sep |
Busiest Day Tue |
Least Busy Day Tue |
Bus providers: Greyhound, FlixBus, The Ride Ann Arbor from Ypsilanti, MI to Chicago, ILYou can travel by bus between Ypsilanti, MI to Chicago, IL with Greyhound, FlixBus, The Ride Ann Arbor for as low as $43 (€35). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Greyhound
The Ride Ann Arbor
FAQs: Bus from Ypsilanti, MI to Chicago, IL
Find answers to the most common questions about traveling from Ypsilanti, MI to Chicago, IL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Chicago, IL, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Millennium Park, a public park known for its modern art installations and the iconic Cloud Gate sculpture
- Art Institute of Chicago, a renowned museum housing an extensive collection of art from around the world
- Navy Pier, a popular entertainment destination featuring rides, restaurants, and lakefront views
- Willis Tower Skydeck, an observation deck offering panoramic views of the city from one of the tallest buildings in the Western Hemisphere
- Field Museum, a natural history museum with vast exhibits including the famous T. rex skeleton, Sue.
- Museum of Science and Industry, an interactive museum featuring exhibits on science, technology, and industry
- Explore the vibrant neighborhoods of Chicago, such as Wicker Park and Lincoln Park, known for their unique shops and eateries
- Take a river cruise to see the city's iconic architecture from a different perspective
- Attend a live performance at the historic Chicago Theatre
- Enjoy a day at Lincoln Park Zoo, one of the oldest zoos in the U.S., offering free admission.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Greyhound
- $15 per additional bag.
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Popular bus stations from Ypsilanti, MI to Chicago, IL
More options for your journey from Ypsilanti, MI to Chicago, IL
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