- Must visit
Art Institute Of Chicago
One of the world’s leading art museums, famous for Impressionist masterpieces, American art, and major special exhibitions.
Cheapest price
$54
Average price
$64
Fastest journey
5 h
Average duration
5 h
Buses per day
2
Distance
336 km
The best way to find a cheap bus ticket from Ypsilanti, MI to Chicago, IL is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Ypsilanti, MI to Chicago, IL will cost around $64 if you buy it on the day, but the cheapest tickets can be found for only $54.
Of the 2 buses that leave Ypsilanti, MI for Chicago, IL on Wed, Jul 08, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Wed, Jul 08 the direct buses cover the 336 km distance in an average of 5 h but if you time it right, some buses will get you there in just 5 h .
On Wed, Jul 08 the slowest buses will take 5 h and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.




Omio recommends booking the train as it is the most popular option from Ypsilanti, MI to Chicago, IL among Omio's users. If you are prioritising price take the bus with prices starting from $42. For those with little time consider booking a flight which can get you there in 1h 34m. The ticket price range depends on the travel mode: a bus costs an average of $42, and a flight costs an average of $332.
Distance: 208 miles (336 km)
| Bus | Most popular Train | Flight |
|---|---|---|
$57 Average price Cheapest | $74 Average price | $388 Average price |
5h 3m Average total duration 4h 33m Onboard + 30m Additional time* | 5h 15m Average total duration 4h 45m Onboard + 30m Additional time* | 4h 34m Average total duration Fastest 1h 34m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Ypsilanti, MI to Chicago, IL:
A bus is $17 (€14) less than a train for this route with tickets for a train from Ypsilanti, MI to Chicago, IL costing on average $74 (€61).
A bus is $331 (€272) less than a flight for this route with tickets for a flight from Ypsilanti, MI to Chicago, IL costing on average $388 (€319).
Other travel options to Chicago, IL take longer:
Bus takes on average 4h 33m.
Train takes on average 4h 45m.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 05:35AM | Arrival Time 11:25AM | Duration 5h50 | Departure days Fri | Cheapest price $42 |
Operator FlixBus | Departure Time 12:15PM | Arrival Time 04:25PM | Duration 4h10 | Departure days Sun | Cheapest price $50 |
Operator FlixBus | Departure Time 01:15PM | Arrival Time 05:25PM | Duration 4h10 | Departure days Fri | Cheapest price $68 |
Operator Amtrak | Departure Time 02:23PM | Arrival Time 07:02PM | Duration 4h39 | Departure days Mon, Thu | Cheapest price $43 |
Operator The Ride Ann Arbor | Departure Time 03:53PM | Arrival Time 09:25PM | Duration 5h32 | Departure days Tue | Cheapest price $64 |
Operator Greyhound | Departure Time 09:25PM | Arrival Time 02:25AM | Duration 5h00 | Departure days Wed, Sat | Cheapest price $61 |
Operator Greyhound | Departure Time 10:25PM | Arrival Time 03:25AM | Duration 5h00 | Departure days Wed, Thu, Fri | Cheapest price $47 |
Operator The Ride Ann Arbor | Departure Time 10:30PM | Arrival Time 05:25AM | Duration 6h55 | Departure days Tue | Cheapest price $64 |
The table below shows live departures for Ypsilanti, MI to Chicago, IL buses for today, Tuesday, July 7. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 10:30 PM Ypsilanti, MI | 6h55 | 5:25 AM Chicago, IL | 2 transfers | |
| Wednesday, July 8 | |||||
![]() | 9:25 PM Ypsilanti, MI | 5h00 | 2:25 AM Chicago, IL | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Ypsilanti, MI to Chicago, IL run on average 4 times per day, taking around 4h 33m. Cheap bus tickets for this journey start at $42 (€35) if you book in advance.
There are 3 buses per day. The earliest bus runs at 00:35, the last at 23:35. The fastest bus covers the 208 miles (336 km) distance in 4h 10m.
Distance 208 miles (336 km) |
Average bus duration 4h 33m |
Cheapest ticket price $42 (€35) |
Buses per day 4 |
Direct buses 3 |
Fastest bus 4h 10m |
First bus 12:35 AM |
Last bus 11:35 PM |
Cheapest Month Aug |
Cheapest Day Mon |
High Season Apr - Jun |
Low Season Jul - Sep |
Busiest Day Tue |
Least Busy Day Tue |
Discover the best of Chicago — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Chicago trip today.
One of the world’s leading art museums, famous for Impressionist masterpieces, American art, and major special exhibitions.
A top natural history museum known for Sue the T. rex, ancient cultures, fossils, and broad science collections.
A large hands-on science museum with a German submarine, space exhibits, and interactive engineering displays.
Chicago’s signature downtown park, home to Cloud Gate, gardens, public art, and major seasonal events.
The city’s best-known avenue for architecture, shopping, and bustling urban energy along North Michigan Avenue.
A popular pedestrian waterfront with excellent skyline views, bridges, and easy access to boat architecture tours.
A thick, buttery crust pizza baked in a deep pan with layers of cheese, toppings, and chunky tomato sauce. It is one of Chicago’s most iconic and debated local specialties.
An all-beef hot dog on a poppy seed bun topped with yellow mustard, relish, onions, tomato, pickle spear, sport peppers, and celery salt. It is a classic local street food served without ketchup.
Thinly sliced seasoned roast beef piled onto an Italian roll, often dipped in its juices and topped with sweet peppers or giardiniera. It is a defining working-class Chicago sandwich.
Chicago’s world-famous fine-dining restaurant known for highly creative tasting menus and theatrical presentation. It offers one of the city’s most celebrated upscale dining experiences.
A beloved casual institution best known for breaded steak sandwiches and hearty Italian-American comfort food. It has a loyal local following and an old-school atmosphere.
A legendary Chicago chain celebrated for buttery-crust deep-dish pizza and a classic casual atmosphere. One of the city’s best-known places to try this signature dish.
Chicago is pricey for hotels and dining, but budget eats and public transit help keep daily costs manageable.
Tip 18-20% at restaurants; 15-20% for taxis and rideshares; USD 1-2 per drink at bars; USD 1-2 per bag for bellhops; USD 2-5 per night for housekeeping.
Find answers to the most common questions about traveling from Ypsilanti, MI to Chicago, IL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Chicago, IL, this guide helps you travel smarter and with confidence.

Most Ypsilanti, MI to Chicago, IL buses use the Ann Arbor, Amtrak Station to Chicago, Greyhound Bus Station station pair, with some services arriving at Chicago, 95th Red Line Station. Use this guide to compare Ypsilanti, MI and Chicago, IL bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Here are some other resources that might have the information you need