- Must visit
Virginia Museum of Transportation
Hands-on transportation museum focused on Roanoke's rail history, with locomotives, model trains, and exhibits inside a former freight station.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 06:45AM | Arrival Time 07:50AM | Duration 1h05 | Departure days Thu | Cheapest price $26 |
Operator Virginia Breeze | Departure Time 12:10PM | Arrival Time 05:50AM | Duration 17h40 | Departure days Mon, Tue, Wed, Sun | Cheapest price $27 |
Compare bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Wytheville, VA to Roanoke, VA run on average 1 times per day, taking around 1h 5m. Cheap bus tickets for this journey start at $18 (€14) if you book in advance.
There are 1 buses per day. The earliest bus runs at 02:35, the last at 12:50. The fastest bus covers the 67 miles (108 km) distance in 1h 5m.
Distance 67 miles (108 km) |
Average bus duration 1h 5m |
Cheapest ticket price $18 (€14) |
Buses per day 1 |
Direct buses 1 |
Fastest bus 1h 5m |
First bus 2:35 AM |
Last bus 12:50 PM |
Cheapest Month Dec |
Cheapest Day Sun |
High Season Jul - Sep |
Low Season Jan - Mar |
Discover the best of Roanoke, VA — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Roanoke, VA trip today.
Hands-on transportation museum focused on Roanoke's rail history, with locomotives, model trains, and exhibits inside a former freight station.
Contemporary and historic art museum in a striking modern building downtown. Its galleries and sculpture spaces make it a leading cultural stop.
Regional history museum covering southwest Virginia through artifacts, photographs, and changing exhibits in downtown Roanoke.
Downtown open-air market district with historic buildings, local shops, and frequent events. It is the city's liveliest area for walking and people-watching.
Mountain park with scenic overlooks, trails, and access to the Roanoke Star. A top outdoor area for views, short hikes, and sunset visits.
Urban greenway following the Roanoke River through parks and downtown. It is ideal for walking, cycling, and seeing the city at a relaxed pace.
Slow-cured Virginia country ham is saltier and drier than typical ham, often served in biscuits. It reflects the curing traditions of Virginia smokehouses.
Brunswick stew is a regional Virginia staple made with slow-cooked chicken or pork, tomatoes, beans, and corn. It is a classic comfort food in western Virginia.
Fried apples are a Southern side of tart apples cooked with butter and spices until tender. They are common in Virginia home cooking and mountain restaurants.
Long-running neighborhood spot serving Texas-style barbecue, smoked meats, and classic Southern sides in a casual setting.
Popular downtown brewery and restaurant with house beers, hearty pub food, and a lively warehouse-style space near the market district.
Stylish farm-to-table restaurant in downtown Roanoke known for seasonal Southern dishes, craft cocktails, and an energetic modern atmosphere.
Moderate by U.S. standards. Hotels and dining are usually cheaper than major cities, while car travel is common and public transit is limited for tourists.
Tip 18-20% at restaurants, 10-15% for taxis, and $1-2 per drink or coffee in cafes if service is good.
Find answers to the most common questions about traveling from Wytheville, VA to Roanoke, VA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Roanoke, VA, this guide helps you travel smarter and with confidence.

Most Wytheville, VA to Roanoke, VA buses use the Wytheville, E Lee Hwy (Sunoco Gas Station) to Roanoke, Third Street Station station pair. Use this guide to compare Wytheville, VA and Roanoke, VA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Wytheville, E Lee Hwy (Sunoco Gas Station) is 20 km from Wytheville city centre. Public transport options include:
Wytheville, E Lee Hwy (Sunoco Gas Station) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Small cafeteria or shop inside the gas station.
Wi-Fi is available at Wytheville, E Lee Hwy (Sunoco Gas Station). ATMs are available at Wytheville, E Lee Hwy (Sunoco Gas Station).
Ticket office support is available at Wytheville, E Lee Hwy (Sunoco Gas Station).
Available at Wytheville, E Lee Hwy (Sunoco Gas Station): Parking, Taxis, WC.
Accessibility facilities are available at Wytheville, E Lee Hwy (Sunoco Gas Station): No dedicated accessibility features.
Roanoke, Third Street Station has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Roanoke, Third Street Station. ATMs are available at Roanoke, Third Street Station.
Ticket office support is available at Roanoke, Third Street Station.
Available at Roanoke, Third Street Station: Parking, Taxis, WC.
Accessibility facilities are available at Roanoke, Third Street Station: Station is wheelchair accessible.
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