- Must visit
Taubman Museum of Art
Major downtown art museum with American art, contemporary exhibitions, and notable architecture by Randall Stout.
Cheapest price
$27
Average price
$27
Fastest journey
17 h 40 m
Average duration
17 h 40 m
Buses per day
1
Distance
108 km
The best way to find a cheap bus ticket from Wytheville, VA to Roanoke, VA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Wytheville, VA to Roanoke, VA will cost around $27 if you buy it on the day, but the cheapest tickets can be found for only $27.
It's difficult to get from Wytheville, VA to Roanoke, VA without transferring at least once.


Omio recommends booking the bus as it is the most popular option from Wytheville, VA to Roanoke, VA among Omio's users. If you are prioritising price take the bus with prices starting from $26. For those with little time consider booking a bus which can get you there in 1h 10m. The ticket price range depends on the travel mode: a bus costs an average of $26, and a bus costs an average of $26.
Distance: 67 miles (108 km)
Most popular Bus | Driving |
|---|---|
$26 Average price Cheapest | $15 Average price (fuel + tolls) |
1h 40m Average total duration Fastest 1h 10m Onboard + 30m Additional time* | 1h 15m Average total duration (door-to-door) |
![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options |
You'll arrive about 5m sooner (1h 10m by bus vs 1h 15m by car). Tickets start at around $26 (€21) compared to roughly $15 (€13) in fuel and tolls — a bit more, but you're getting time back, skipping traffic and parking, and you can work or rest on board.
Direct coaches are operated by Greyhound.
Driving makes more sense if you're travelling as a group (where fuel splits across several people), want flexibility on timing, or plan to stop en route.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 06:45AM | Arrival Time 07:50AM | Duration 1h05 | Departure days Thu | Cheapest price $26 |
Operator Virginia Breeze | Departure Time 12:10PM | Arrival Time 05:50AM | Duration 17h40 | Departure days Mon, Tue, Wed, Sun | Cheapest price $27 |
Compare bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Wytheville, VA to Roanoke, VA run on average 1 times per day, taking around 1h 10m. Cheap bus tickets for this journey start at $26 (€21) if you book in advance.
There are 1 buses per day. The earliest bus runs at 02:35, the last at 12:50. The fastest bus covers the 67 miles (108 km) distance in 1h 5m.
Distance 67 miles (108 km) |
Average bus duration 1h 10m |
Cheapest ticket price $26 (€21) |
Buses per day 1 |
Direct buses 1 |
Fastest bus 1h 5m |
First bus 2:35 AM |
Last bus 12:50 PM |
Cheapest Month Dec |
Cheapest Day Mon |
High Season Oct - Dec |
Low Season Jan - Mar |
Discover the best of Roanoke — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Roanoke trip today.
Major downtown art museum with American art, contemporary exhibitions, and notable architecture by Randall Stout.
Well-known rail and transportation museum featuring locomotives, vintage railcars, and Virginia transport history.
Specialty museum dedicated to the photography and sound recordings of railroad photographer O. Winston Link.
Large mountain park with scenic overlooks, trails, the famous star, and some of the best panoramic city views.
Walkable city center with historic architecture, museums, nightlife, and frequent events around the market area.
Scenic mountain viewpoints just outside the city, especially popular for sunsets, foliage, and social-media photos.
Salt-cured Virginia ham served in soft biscuits, a classic Southwest Virginia breakfast and snack with deep regional roots.
A Southern spread made with cheddar, pimentos, and mayonnaise, commonly served with crackers or sandwiches in Virginia eateries.
A thick regional stew usually made with chicken or pork, tomatoes, beans, and vegetables, long associated with Virginia food traditions.
Well-regarded farm-to-table restaurant known for refined Southern cuisine, seasonal ingredients, and a polished but welcoming atmosphere.
Established South Roanoke favorite serving upscale New American dishes, cocktails, and brunch in a stylish neighborhood setting.
Historic downtown diner famous for chili dogs, burgers, and late-night comfort food in a tiny, classic Roanoke setting.
Costs are moderate by U.S. standards. Hotels and dining are usually cheaper than in major coastal cities.
Tip 18-20% at restaurants. Tip USD 1-2 per drink at bars, round up taxis, and tip hotel staff and drivers for good service.
Find answers to the most common questions about traveling from Wytheville, VA to Roanoke, VA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Roanoke, VA, this guide helps you travel smarter and with confidence.

Most Wytheville, VA to Roanoke, VA buses use the Wytheville, E Lee Hwy (Sunoco Gas Station) to Roanoke, Third Street Station station pair. Use this guide to compare Wytheville, VA and Roanoke, VA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Here are some other resources that might have the information you need