- Must visit
Virginia Museum of Transportation
Hands-on transportation museum focused on Roanoke's rail history, with locomotives, model trains, and exhibits inside a former freight station.
Cheapest price on Sep 21
$102
Average ticket price on Sep 21
$102
Fastest journey on Sep 21
17 h 45 m
Average journey duration on Sep 21
17 h 45 m
Buses on Sep 21
1
Distance
295 km
The best way to find a cheap bus ticket from Greenville, NC to Roanoke, VA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Greenville, NC to Roanoke, VA will cost around $102 if you buy it on the day, but the cheapest tickets can be found for only $102.
On Mon, Sep 21, we found 1 buses from Greenville, NC to Roanoke, VA, including 1 direct services.
On Mon, Sep 21 the direct buses cover the 295 km distance in an average of 17 h 45 m but if you time it right, some buses will get you there in just 17 h 45 m .
On Mon, Sep 21 the slowest buses will take 17 h 45 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Omio recommends booking the bus as it is the most popular option from Greenville, NC to Roanoke, VA among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $99 For those with little time, consider booking a bus, which has an average total journey time of 13h 40m. Average ticket prices depend on the travel mode: a bus costs an average of $99, while a bus costs an average of $99.
Distance: 183 miles (295 km)
Most popular Bus | Driving |
|---|---|
$99 Average price Cheapest | $47 Average price (fuel + tolls) |
13h 40m Average total duration Fastest 13h 10m Onboard + 30m Additional time* | 4h 16m Average total duration (door-to-door) |
![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options |
Tickets start at around $99 (€81) compared to roughly $47 (€39) in fuel and tolls — a saving of about $-51.80 (€-42.37). The journey takes 13h 10m versus 4h 16m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 11:20PM | Arrival Time 05:05PM | Duration 17h45 | Departure days Mon, Tue, Thu | Cheapest price $102 |
Compare bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Greenville, NC to Roanoke, VA run on average 1 times per day, taking around 13h 10m. Cheap bus tickets for this journey start at $99 (€81) if you book in advance.
The earliest bus runs at 18:20, the last at 18:20. The fastest bus covers the 183 miles (295 km) distance in 13h 10m.
Distance 183 miles (295 km) |
Average bus duration 13h 10m |
Cheapest ticket price $99 (€81) |
Buses per day 1 |
Fastest bus 13h 10m |
First bus 6:20 PM |
Last bus 6:20 PM |
Cheapest Month Mar |
Cheapest Day Mon |
High Season Jan - Mar |
Low Season Oct - Dec |
Discover the best of Roanoke, VA — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Roanoke, VA trip today.
Hands-on transportation museum focused on Roanoke's rail history, with locomotives, model trains, and exhibits inside a former freight station.
Contemporary and historic art museum in a striking modern building downtown. Its galleries and sculpture spaces make it a leading cultural stop.
Regional history museum covering southwest Virginia through artifacts, photographs, and changing exhibits in downtown Roanoke.
Downtown open-air market district with historic buildings, local shops, and frequent events. It is the city's liveliest area for walking and people-watching.
Mountain park with scenic overlooks, trails, and access to the Roanoke Star. A top outdoor area for views, short hikes, and sunset visits.
Urban greenway following the Roanoke River through parks and downtown. It is ideal for walking, cycling, and seeing the city at a relaxed pace.
Find answers to the most common questions about traveling from Greenville, NC to Roanoke, VA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Roanoke, VA, this guide helps you travel smarter and with confidence.

Most Greenville, NC to Roanoke, VA buses use the Greenville, S Pitt St (Butterfield Transportation Center) to Roanoke, Third Street Station station pair. Use this guide to compare Greenville, NC and Roanoke, VA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Greenville, S Pitt St (Butterfield Transportation Center) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Free wifi available in waiting areas. ATMs are available at Greenville, S Pitt St (Butterfield Transportation Center).
Ticket office support is available at Greenville, S Pitt St (Butterfield Transportation Center).
Available at Greenville, S Pitt St (Butterfield Transportation Center): Parking, Taxis, WC.
Accessibility facilities are available at Greenville, S Pitt St (Butterfield Transportation Center): Wheelchair accessible entrances and seating areas.
Roanoke, Third Street Station has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Roanoke, Third Street Station. ATMs are available at Roanoke, Third Street Station.
Ticket office support is available at Roanoke, Third Street Station.
Available at Roanoke, Third Street Station: Parking, Taxis, WC.
Accessibility facilities are available at Roanoke, Third Street Station: Station is wheelchair accessible.
Here are some other resources that might have the information you need