The cheapest and fastest buses from Vandalia, OH to Chicago, IL
Cheapest price
$54
Average price
$63
Fastest journey
6 h 42 m
Average duration
6 h 50 m
Buses per day
2
Distance
363 km
The best way to find a cheap bus ticket from Vandalia, OH to Chicago, IL is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Vandalia, OH to Chicago, IL will cost around $63 if you buy it on the day, but the cheapest tickets can be found for only $54.
It's difficult to get from Vandalia, OH to Chicago, IL without transferring at least 2 times.




Travel Information
Compare bus and flight for Vandalia, OH to Chicago, IL
Omio recommends booking the flight as it is the most popular option from Vandalia, OH to Chicago, IL among Omio's users. If you are prioritising price take the bus with prices starting from $51. For those with little time consider booking a flight which can get you there in 1h 38m. The ticket price range depends on the travel mode: a bus costs an average of $51, and a flight costs an average of $334.
Distance: 225 miles (363 km)
Compare bus with
| Bus | Most popular Flight |
|---|---|
$53 Average price Cheapest | $337 Average price |
6h 50m Average total duration 6h 20m Onboard + 30m Additional time* | 4h 38m Average total duration Fastest 1h 38m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options |
Live departures
Vandalia, OH to Chicago, IL bus times
The table below shows live departures for Vandalia, OH to Chicago, IL buses for today, Saturday, March 21. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 9:33 AM Vandalia, OH | 6h42 | 4:15 PM Chicago, IL | 2 transfers | |
| Sunday, March 22 | |||||
![]() | 6:37 AM Vandalia, OH | 6h58 | 1:35 PM Chicago, IL | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Vandalia, OH to Chicago, IL by bus or flight
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Mar 22
Mar 23
Mar 24
Mar 25
Mar 26
Mar 27
Mar 28
Journey information
Overview: Bus from Vandalia, OH to Chicago, IL
Buses from Vandalia, OH to Chicago, IL run on average 5 times per day, taking around 6h 20m. Cheap bus tickets for this journey start at $51 (€41) if you book in advance.
There are 3 buses per day. The earliest bus runs at 00:35, the last at 23:10. The fastest bus covers the 225 miles (363 km) distance in 6h 20m.
Distance 225 miles (363 km) |
Average bus duration 6h 20m |
Cheapest ticket price $51 (€41) |
Buses per day 5 |
Direct buses 3 |
Fastest bus 6h 20m |
First bus 00:35 |
Last bus 23:10 |
Bus providers: Dayton RTA from Vandalia, OH to Chicago, ILYou can travel by bus between Vandalia, OH to Chicago, IL with Dayton RTA for as low as $51 (€41). When you search for schedules and tickets, Omio will show you the best journey
Dayton RTA
FAQs: Bus from Vandalia, OH to Chicago, IL
Find answers to the most common questions about traveling from Vandalia, OH to Chicago, IL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Chicago, IL, this guide helps you travel smarter and with confidence.

- Millennium Park, a public park known for its modern art installations and the iconic Cloud Gate sculpture
- Art Institute of Chicago, a renowned museum housing an extensive collection of art from around the world
- Navy Pier, a popular entertainment destination featuring rides, restaurants, and lakefront views
- Willis Tower Skydeck, an observation deck offering panoramic views of the city from one of the tallest buildings in the Western Hemisphere
- Field Museum, a natural history museum with vast exhibits including the famous T. rex skeleton, Sue.
- Museum of Science and Industry, an interactive museum featuring exhibits on science, technology, and industry
- Explore the vibrant neighborhoods of Chicago, such as Wicker Park and Lincoln Park, known for their unique shops and eateries
- Take a river cruise to see the city's iconic architecture from a different perspective
- Attend a live performance at the historic Chicago Theatre
- Enjoy a day at Lincoln Park Zoo, one of the oldest zoos in the U.S., offering free admission.
popular bus stations
Popular bus stations from Vandalia, OH to Chicago, IL
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