- Must visit
Art Institute Of Chicago
One of the premier art museums in the US, known for Impressionist masterpieces, modern works, and the iconic bronze lions at its entrance.
Cheapest price
$54
Average price
$63
Fastest journey
6 h 42 m
Average duration
6 h 50 m
Buses per day
2
Distance
363 km
The best way to find a cheap bus ticket from Vandalia, OH to Chicago, IL is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Vandalia, OH to Chicago, IL will cost around $63 if you buy it on the day, but the cheapest tickets can be found for only $54.
It's difficult to get from Vandalia, OH to Chicago, IL without transferring at least 2 times.




Omio recommends booking the flight as it is the most popular option from Vandalia, OH to Chicago, IL among Omio's users. If you are prioritising price take the bus with prices starting from $50. For those with little time consider booking a flight which can get you there in 1h 36m. The ticket price range depends on the travel mode: a bus costs an average of $50, and a flight costs an average of $315.
Distance: 225 miles (363 km)
| Bus | Most popular Flight | Driving |
|---|---|---|
$60 Average price Cheapest | $351 Average price | $54 Average price (fuel + tolls) |
6h 56m Average total duration 6h 26m Onboard + 30m Additional time* | 4h 36m Average total duration Fastest 1h 36m Onboard + 3h 0m Additional time* | 4h 17m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Vandalia, OH to Chicago, IL:
A bus is $292 (€239) less than a flight for this route with tickets for a flight from Vandalia, OH to Chicago, IL costing on average $351 (€287).
Other travel options to Chicago, IL take longer:
Bus takes on average 6h 26m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 04:35AM | Arrival Time 11:10AM | Duration 6h35 | Departure days Thu | Cheapest price $53 |
Operator FlixBus | Departure Time 05:35AM | Arrival Time 12:10PM | Duration 6h35 | Departure days Tue | Cheapest price $53 |
Operator Dayton RTA | Departure Time 06:37AM | Arrival Time 01:35PM | Duration 6h58 | Departure days Wed, Sat, Sun | Cheapest price $72 |
Operator Dayton RTA | Departure Time 09:33AM | Arrival Time 04:15PM | Duration 6h42 | Departure days Wed, Sat, Sun | Cheapest price $54 |
Operator FlixBus | Departure Time 02:55PM | Arrival Time 09:15PM | Duration 6h20 | Departure days Fri | Cheapest price $97 |
Operator FlixBus | Departure Time 03:55PM | Arrival Time 10:15PM | Duration 6h20 | Departure days Mon, Fri | Cheapest price $50 |
The table below shows live departures for Vandalia, OH to Chicago, IL buses for tomorrow, Saturday, June 20. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 6:37 AM Vandalia, OH | 6h58 | 1:35 PM Chicago, IL | 2 transfers | |
![]() | 9:33 AM Vandalia, OH | 6h42 | 4:15 PM Chicago, IL | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Vandalia, OH to Chicago, IL run on average 5 times per day, taking around 6h 26m. Cheap bus tickets for this journey start at $50 (€41) if you book in advance.
There are 3 buses per day. The earliest bus runs at 00:35, the last at 23:10. The fastest bus covers the 225 miles (363 km) distance in 6h 20m.
Distance 225 miles (363 km) |
Average bus duration 6h 26m |
Cheapest ticket price $50 (€41) |
Buses per day 5 |
Direct buses 3 |
Fastest bus 6h 20m |
First bus 12:35 AM |
Last bus 11:10 PM |
Cheapest Month Mar |
Cheapest Day Mon |
High Season Jan - Mar |
Low Season Apr - Jun |
Discover the best of Chicago — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Chicago trip today.
One of the premier art museums in the US, known for Impressionist masterpieces, modern works, and the iconic bronze lions at its entrance.
Major natural history museum famous for Sue the T. rex, ancient cultures, and extensive science collections that appeal to both adults and children.
Large hands-on science museum in Hyde Park featuring a submarine, space exhibits, engineering displays, and immersive family-friendly experiences.
The city’s signature public space, home to Cloud Gate, gardens, events, and major skyline views that define modern Chicago.
Famous stretch of Michigan Avenue lined with historic buildings, shops, hotels, and frequent first-time visitor photo stops.
Highly popular waterfront promenade with architecture views, bridges, and one of the best urban walks in the city.
Chicago’s iconic thick-crust pizza baked in a deep pan, layered with cheese, toppings, and chunky tomato sauce. It is one of the city’s most famous comfort foods.
An all-beef hot dog on a poppy seed bun topped with mustard, onions, neon relish, tomato, pickle spear, sport peppers, and celery salt. It is a classic local street food.
Thinly sliced roast beef piled onto an Italian roll, often dipped in seasoned jus and topped with sweet peppers or giardiniera. It is a defining Chicago sandwich.
A historic old-school steakhouse serving steaks, chops, and classic Italian-American dishes in a traditional setting.
Chicago’s internationally acclaimed fine-dining restaurant known for highly inventive tasting menus and exceptional service.
A long-established Chicago favorite known for buttery deep-dish pizza and a casual, family-friendly atmosphere.
Moderate for a major U.S. city: casual food is manageable, but hotels, attractions, and downtown dining can be pricey.
Tip 18-20% in restaurants; 20%+ for great service. Tip bartenders USD 1-2 per drink, taxis about 10-15%, and hotel staff a few dollars.
Find answers to the most common questions about traveling from Vandalia, OH to Chicago, IL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Chicago, IL, this guide helps you travel smarter and with confidence.

Most Vandalia, OH to Chicago, IL buses use the Trotwood, Salem Ave (Greyhound Bus Station) to Chicago, Greyhound Bus Station station pair, with some services arriving at Chicago, Union Station (Amtrak). Use this guide to compare Vandalia, OH and Chicago, IL bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Here are some other resources that might have the information you need