- Must visit
Art Institute Of Chicago
One of the premier art museums in the US, known for Impressionist masterpieces, modern works, and the iconic bronze lions at its entrance.
Cheapest price
$135
Average price
$135
Fastest journey
17 h 10 m
Average duration
17 h 10 m
Buses per day
1
Distance
797 km
The best way to find a cheap bus ticket from Tyrone, PA to Chicago, IL is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Tyrone, PA to Chicago, IL will cost around $135 if you buy it on the day, but the cheapest tickets can be found for only $135.
Of the 1 buses that leave Tyrone, PA for Chicago, IL on Sun, Jun 21, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sun, Jun 21 the direct buses cover the 797 km distance in an average of 17 h 10 m but if you time it right, some buses will get you there in just 17 h 10 m .
On Sun, Jun 21 the slowest buses will take 17 h 10 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Omio recommends booking the train as it is the most popular option from Tyrone, PA to Chicago, IL among Omio's users. If you are prioritising price take the bus with prices starting from $135. For those with little time consider booking a train which can get you there in 15h 54m. The ticket price range depends on the travel mode: a bus costs an average of $135, and a train costs an average of $284.
Distance: 495 miles (797 km)
| Bus | Most popular Train | Driving |
|---|---|---|
$135 Average price Cheapest | $284 Average price | $114 Average price (fuel + tolls) |
17h 40m Average total duration 17h 10m Onboard + 30m Additional time* | 16h 24m Average total duration Fastest 15h 54m Onboard + 30m Additional time* | 8h 33m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Tyrone, PA to Chicago, IL:
A bus is $149 (€122) less than a train for this route with tickets for a train from Tyrone, PA to Chicago, IL costing on average $284 (€232).
Other travel options to Chicago, IL take longer:
Bus takes on average 17h 10m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound USA | Departure Time 02:00PM | Arrival Time 06:10AM | Duration 16h10 | Departure days Mon, Tue, Wed, Thu, Fri | Cheapest price $115 |
Operator FlixBus | Departure Time 06:00PM | Arrival Time 11:10AM | Duration 17h10 | Departure days Sun | Cheapest price $135 |
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Tyrone, PA to Chicago, IL run on average 2 times per day, taking around 17h 10m. Cheap bus tickets for this journey start at $135 (€110) if you book in advance.
The earliest bus runs at 10:00, the last at 19:15. The fastest bus covers the 495 miles (797 km) distance in 17h 10m.
Distance 495 miles (797 km) |
Average bus duration 17h 10m |
Cheapest ticket price $135 (€110) |
Buses per day 2 |
Fastest bus 17h 10m |
First bus 10:00 AM |
Last bus 7:15 PM |
Cheapest Month Jul |
Cheapest Day Wed |
High Season Jan - Mar |
Low Season Jul - Sep |
Discover the best of Chicago — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Chicago trip today.
One of the premier art museums in the US, known for Impressionist masterpieces, modern works, and the iconic bronze lions at its entrance.
Major natural history museum famous for Sue the T. rex, ancient cultures, and extensive science collections that appeal to both adults and children.
Large hands-on science museum in Hyde Park featuring a submarine, space exhibits, engineering displays, and immersive family-friendly experiences.
The city’s signature public space, home to Cloud Gate, gardens, events, and major skyline views that define modern Chicago.
Famous stretch of Michigan Avenue lined with historic buildings, shops, hotels, and frequent first-time visitor photo stops.
Highly popular waterfront promenade with architecture views, bridges, and one of the best urban walks in the city.
Chicago’s iconic thick-crust pizza baked in a deep pan, layered with cheese, toppings, and chunky tomato sauce. It is one of the city’s most famous comfort foods.
An all-beef hot dog on a poppy seed bun topped with mustard, onions, neon relish, tomato, pickle spear, sport peppers, and celery salt. It is a classic local street food.
Thinly sliced roast beef piled onto an Italian roll, often dipped in seasoned jus and topped with sweet peppers or giardiniera. It is a defining Chicago sandwich.
A historic old-school steakhouse serving steaks, chops, and classic Italian-American dishes in a traditional setting.
Chicago’s internationally acclaimed fine-dining restaurant known for highly inventive tasting menus and exceptional service.
A long-established Chicago favorite known for buttery deep-dish pizza and a casual, family-friendly atmosphere.
Moderate for a major U.S. city: casual food is manageable, but hotels, attractions, and downtown dining can be pricey.
Tip 18-20% in restaurants; 20%+ for great service. Tip bartenders USD 1-2 per drink, taxis about 10-15%, and hotel staff a few dollars.
Find answers to the most common questions about traveling from Tyrone, PA to Chicago, IL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Chicago, IL, this guide helps you travel smarter and with confidence.

Most Tyrone, PA to Chicago, IL buses use the Tyrone, Pennsylvania Ave (Train Station) to Chicago, Greyhound Bus Station station pair, with some services arriving at Chicago, Union Station (Amtrak). Use this guide to compare Tyrone, PA and Chicago, IL bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Here are some other resources that might have the information you need