- Must visit
Art Institute of Chicago
World-class art museum with masterpieces from Monet to Hopper and the famous Modern Wing.
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Travel Information
Compare train and bus for Tyrone, PA to Chicago, IL
Omio recommends booking the train as it is the most popular option from Tyrone, PA to Chicago, IL among Omio's users.
Distance: 495 miles (797 km)
Compare bus with
| Bus | Most popular Train | Driving |
|---|---|---|
€95 Average price (fuel + tolls) | ||
8h 33m Average total duration (door-to-door) | ||
Direct Options | Direct Options | Direct Options |
Tyrone, PA to Chicago, IL Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound USA | Departure Time 02:00PM | Arrival Time 06:10AM | Duration 16h10 | Departure days Mon, Tue, Wed, Thu, Fri | Cheapest price €94 |
Operator FlixBus | Departure Time 06:00PM | Arrival Time 11:10AM | Duration 17h10 | Departure days Sun | Cheapest price €110 |
Live departures
Tyrone, PA to Chicago, IL bus times
The table below shows live departures for Tyrone, PA to Chicago, IL buses for today, Friday, September 18. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
 | 2:00 PM Tyrone, PA | 16h10 | 6:10 AM Chicago, IL | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Tyrone, PA to Chicago, IL by train or bus
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Tyrone, PA to Chicago, IL buses with Omio?
Greyhound operates all buses services from Tyrone, PA to Chicago, IL.
Omio is an official ticket reseller for all your travel options from Tyrone, PA to Chicago, IL.
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are train and bus to ensure you get the best deal for traveling from Tyrone, PA to Chicago, IL.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including train and bus to find the ideal travel option from Tyrone, PA to Chicago, IL.
Journey information
Overview: Bus from Tyrone, PA to Chicago, IL
USAUSA
Take a bus from Tyrone, PA to Chicago, IL and enjoy the approximately 495 miles (797 km) long journey. Find schedules and pricing options for a convenient and affordable trip.
The earliest bus runs at 10:00, the last at 19:15.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 495 miles (797 km) |
First bus 10:00 AM |
Last bus 7:15 PM |
Cheapest Month Mar |
Cheapest Day Wed |
High Season Apr - Jun |
Low Season Oct - Dec |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Complete guide to Chicago, IL
Things to do in Chicago, IL
Discover the best of Chicago, IL — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Chicago, IL trip today.
- Must visit
Field Museum
Major natural history museum with Sue the T. rex, ancient cultures, and strong family appeal.
- Must visit
Museum of Science and Industry
Hands-on science museum in a grand former fair building, popular for exhibits and a U-505 submarine.
- Must visit
Millennium Park
Lively lakefront park with Cloud Gate, Crown Fountain, gardens, and major public art in central Chicago.
- Must visit
Magnificent Mile
Famous shopping boulevard lined with architecture, hotels, riverfront views, and major city energy.
- Must visit
Chicago Riverwalk
Scenic pedestrian-friendly riverwalk with boat docks, public art, bridges, and standout skyline perspectives.
Deep-Dish Pizza
Deep-dish pizza is Chicago’s iconic pie with a tall buttery crust, layers of cheese and toppings, and chunky tomato sauce baked on top.
Chicago-Style Hot Dog
The Chicago-style hot dog is an all-beef frank on a poppy seed bun with mustard, relish, onion, tomato, pickle, peppers, and celery salt.
Italian Beef Sandwich
Italian beef is thin-sliced roast beef piled onto a roll, often dipped in savory juices and topped with sweet peppers or spicy giardiniera.
Johnnie's Beef
Classic spot for juicy Italian beef sandwiches, especially dipped and topped with spicy giardiniera, with a casual local feel.
Superdawg Drive-In
Legendary stand for Chicago-style hot dogs and char-grilled sausages, served fast in a no-frills local landmark.
Alinea
World-famous fine dining destination offering a highly creative tasting menu and refined service in an elegant setting.
US dollar ($)
Moderate for a major US city: hotels can be pricey, but transit is affordable and dining ranges from cheap eats to upscale options.
Average meal costs
- Budget
- $10-18 for fast food or casual takeout.
- Mid-range
- $20-40 per person for a restaurant meal.
- Fine dining
- $75+ per person for upscale restaurants.
- Coffee
- $3-6 for coffee or cappuccino.
Tipping culture
Tip 18-20% at restaurants, $1-2 per drink at bars, 10-15% for taxis, and optional small change at cafes.
FAQs: Bus from Tyrone, PA to Chicago, IL
Find answers to the most common questions about traveling from Tyrone, PA to Chicago, IL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Chicago, IL, this guide helps you travel smarter and with confidence.
popular bus stations
Popular bus stations from Tyrone, PA to Chicago, IL
Most Tyrone, PA to Chicago, IL buses use the Tyrone, Pennsylvania Ave (Train Station) to Chicago, Greyhound Bus Station station pair, with some services arriving at Chicago, Union Station (Amtrak). Use this guide to compare Tyrone, PA and Chicago, IL bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in Tyrone
Arrival bus stations in Chicago
Which Tyrone, PA station do buses to Chicago, IL leave from?
Buses from Tyrone, PA to Chicago, IL leave from Tyrone, Pennsylvania Ave (Train Station). The station is from Tyrone, PA city centre at Pennsylvania Ave, Tyrone, PA 16686, USA.
Tyrone, Pennsylvania Ave (Train Station)Pennsylvania Ave, Tyrone, PA 16686, USA
City-centre transport
Getting to Tyrone, Pennsylvania Ave (Train Station) from Tyrone city centre
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Tyrone, Pennsylvania Ave (Train Station) bus station facilities and services
Tyrone, Pennsylvania Ave (Train Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Tyrone, Pennsylvania Ave (Train Station). ATMs are available at Tyrone, Pennsylvania Ave (Train Station).
Tickets and information
Ticket office support is available at Tyrone, Pennsylvania Ave (Train Station).
Parking, taxis and toilets
Available at Tyrone, Pennsylvania Ave (Train Station): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Tyrone, Pennsylvania Ave (Train Station): Bus boarding area has wheelchair access.
Which Chicago, IL station do buses from Tyrone, PA arrive at?
Buses from Tyrone, PA to Chicago, IL most often arrive at Chicago, Greyhound Bus Station. Some services arrive at Chicago, Union Station (Amtrak), so check your ticket before travel to confirm your Chicago, IL arrival station.
Chicago, Greyhound Bus Station630 W Harrison St, Chicago, IL 60607, USA
City-centre transport
Getting to Chicago, Greyhound Bus Station from Chicago city centre
Chicago, Greyhound Bus Station is 2 km from Chicago city centre. Public transport options include:
Bus7 · 8m · €3 · every ~6 min
Chicago, Greyhound Bus Station bus station facilities and services
Chicago, Greyhound Bus Station has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Snack shop and vending machines available
Wi-Fi and ATMs
Free Wi-Fi in waiting area. ATMs are located near entrance.
Tickets and information
Ticket office support is available at Chicago, Greyhound Bus Station.
Parking, taxis and toilets
Available at Chicago, Greyhound Bus Station: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Chicago, Greyhound Bus Station: Wheelchair accessible entrances and seating.
Chicago, Union Station (Amtrak)Chicago Union Station, 225 S Canal St, Chicago, IL 60606, USA
City-centre transport
Getting to Chicago, Union Station (Amtrak) from Chicago city centre
Chicago, Union Station (Amtrak) is 3 km from Chicago city centre. Public transport options include:
Bus28, 151 · 7m · €3 · every ~13 min
Chicago, Union Station (Amtrak) bus station facilities and services
Chicago, Union Station (Amtrak) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Multiple dining options are available inside the station.
Wi-Fi and ATMs
Free Wi-Fi is available in waiting areas. ATMs are aTMs are located near the main entrance.
Tickets and information
Ticket office support is available at Chicago, Union Station (Amtrak).
Parking, taxis and toilets
Available at Chicago, Union Station (Amtrak): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Chicago, Union Station (Amtrak): Station is accessible with elevators and ramps.
More options for your journey from Tyrone, PA to Chicago, IL
Here are some other resources that might have the information you need
Most popular buses to and from Chicago, IL and Tyrone, PA
Most popular bus connections to Chicago, IL
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