The cheapest and fastest buses from Tyrone, PA to Chicago, IL
Cheapest price
$296
Average price
$296
Fastest journey
1 d 6 h 5 m
Average duration
1 d 6 h 5 m
Buses per day
1
Distance
797 km
The best way to find a cheap bus ticket from Tyrone, PA to Chicago, IL is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Tyrone, PA to Chicago, IL will cost around $296 if you buy it on the day, but the cheapest tickets can be found for only $296.
It's difficult to get from Tyrone, PA to Chicago, IL without transferring at least once.


Travel Information
Compare train and bus for Tyrone, PA to Chicago, IL
Omio recommends booking the bus as it is the most popular option from Tyrone, PA to Chicago, IL among Omio's users. If you are prioritising price take the bus with prices starting from €104. For those with little time consider booking a train which can get you there in 16h 54m. The ticket price range depends on the travel mode: a bus costs an average of €104, and a train costs an average of €159.
Distance: 495 miles (797 km)
Compare bus with
Most popular Bus | Train |
|---|---|
€104 Average price Cheapest | €159 Average price |
17h 40m Average total duration 17h 10m Onboard + 30m Additional time* | 17h 24m Average total duration Fastest 16h 54m Onboard + 30m Additional time* |
Direct Options | Direct Options |
Live departures
Tyrone, PA to Chicago, IL bus times
The table below shows live departures for Tyrone, PA to Chicago, IL buses for tomorrow, Thursday, November 6. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 2:00 PM Tyrone, PA | 30h05 | 8:05 PM Chicago, IL | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Tyrone, PA to Chicago, IL by train or bus
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Nov 06
Nov 07
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Nov 10
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Nov 12
Journey information
Overview: Bus from Tyrone, PA to Chicago, IL
Distance 495 miles (797 km) |
Average bus duration 17h 10m |
Cheapest ticket price $128 (€104) |
Buses per day 2 |
Fastest bus 17h 10m |
First bus 10:00 |
Last bus 19:15 |
Key Takeaways
Train Ticket Prices
- Budget Options: Train tickets from Tyrone, PA to Chicago, IL start from as low as $128 (€104) if booked well in advance.
- Standard Fares: Typically, trains cost $128 (€104) depending on the train type and class.
Bus providers: Greyhound from Tyrone, PA to Chicago, ILYou can travel by bus between Tyrone, PA to Chicago, IL with Greyhound for as low as $128 (€104). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
FAQs: Bus from Tyrone, PA to Chicago, IL
Find answers to the most common questions about traveling from Tyrone, PA to Chicago, IL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Chicago, IL, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Millennium Park, a public park known for its modern art installations and the iconic Cloud Gate sculpture
- Art Institute of Chicago, a renowned museum housing an extensive collection of art from around the world
- Navy Pier, a popular entertainment destination featuring rides, restaurants, and lakefront views
- Willis Tower Skydeck, an observation deck offering panoramic views of the city from one of the tallest buildings in the Western Hemisphere
- Field Museum, a natural history museum with vast exhibits including the famous T. Rex skeleton, Sue.
- Museum of Science and Industry, an interactive museum featuring exhibits on science, technology, and industry
- Explore the vibrant neighborhoods of Chicago, such as Wicker Park and Lincoln Park, known for their unique shops and eateries
- Take a river cruise to see the city's iconic architecture from a different perspective
- Attend a live performance at the historic Chicago Theatre
- Enjoy a day at Lincoln Park Zoo, one of the oldest zoos in the U. S. Offering free admission.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
To find the cheapest bus tickets for your trip from Tyrone, PA to Chicago, IL, follow these tips:
Start your search now and compare ticket prices to find the best deal!
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from Tyrone, PA to Chicago, IL
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