Travel Information
Compare bus and flight for Tuscaloosa, AL to Louisville, KY
Omio recommends booking the flight as it is the most popular option from Tuscaloosa, AL to Louisville, KY among Omio's users. If you are prioritising price take the bus with prices starting from $157. For those with little time consider booking a flight which can get you there in 4h 46m. The ticket price range depends on the travel mode: a bus costs an average of $157, and a flight costs an average of $410.
Distance: 362 miles (584 km)
Compare bus with
| Bus | Most popular Flight | Driving |
|---|---|---|
$171 Average price Cheapest | $466 Average price | $15 Average price (fuel + tolls) |
16h 2m Average total duration 15h 32m Onboard + 30m Additional time* | 7h 46m Average total duration Fastest 4h 46m Onboard + 3h 0m Additional time* | 5h 59m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Tuscaloosa, AL to Louisville, KY:
A bus is $295 (€238) less than a flight for this route with tickets for a flight from Tuscaloosa, AL to Louisville, KY costing on average $466 (€376).
Other travel options to Louisville, KY take longer:
Bus takes on average 15h 32m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
Tuscaloosa, AL to Louisville, KY Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 01:50AM | Arrival Time 06:10PM | Duration 16h20 | Departure days Wed | Cheapest price $157 |
Operator Greyhound USA | Departure Time 07:45AM | Arrival Time 08:00AM | Duration 24h15 | Departure days Wed, Fri, Sun | Cheapest price $120 |
Operator Greyhound | Departure Time 03:10PM | Arrival Time 06:30AM | Duration 15h20 | Departure days Sat | Cheapest price $160 |
Operator Greyhound | Departure Time 10:40PM | Arrival Time 01:35PM | Duration 14h55 | Departure days Thu | Cheapest price $197 |
Compare prices and tickets Tuscaloosa, AL to Louisville, KY by bus or flight
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Tuscaloosa, AL to Louisville, KY buses with Omio?
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus and flight to ensure you get the best deal for traveling from Tuscaloosa, AL to Louisville, KY.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including bus and flight to find the ideal travel option from Tuscaloosa, AL to Louisville, KY.
Journey information
Overview: Bus from Tuscaloosa, AL to Louisville, KY
Buses from Tuscaloosa, AL to Louisville, KY run on average 3 times per day, taking around 15h 32m. Cheap bus tickets for this journey start at $157 (€126) if you book in advance.
The earliest bus runs at 06:00, the last at 22:55. The fastest bus covers the 362 miles (584 km) distance in 14h 55m.
Distance 362 miles (584 km) |
Average bus duration 15h 32m |
Cheapest ticket price $157 (€126) |
Buses per day 3 |
Fastest bus 14h 55m |
First bus 6:00 AM |
Last bus 10:55 PM |
Cheapest Month May |
Cheapest Day Fri |
High Season Apr - Jun |
Low Season Jan - Mar |
Bus providers: Greyhound from Tuscaloosa, AL to Louisville, KYYou can travel by bus between Tuscaloosa, AL to Louisville, KY with Greyhound for as low as $157 (€126). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
FAQs: Bus from Tuscaloosa, AL to Louisville, KY
Find answers to the most common questions about traveling from Tuscaloosa, AL to Louisville, KY by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Louisville, KY, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from Tuscaloosa, AL to Louisville, KY
Most popular bus connections from Tuscaloosa, AL
More options for your journey from Tuscaloosa, AL to Louisville, KY
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