The cheapest and fastest buses from Derby to Manchester
Cheapest price
$18
Average price
$25
Fastest journey
4 h 10 m
Average duration
4 h 35 m
Buses per day
7
Distance
80 km
The best way to find a cheap bus ticket from Derby to Manchester is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Derby to Manchester will cost around $25 if you buy it on the day, but the cheapest tickets can be found for only $18.
It's difficult to get from Derby to Manchester without transferring at least once.
NX134 · NX121
NX134 · NX171
FlixBus · FlixBus
NX133 · NX120
FlixBus · FlixBus
NX134 · NX171
NX133 · NX120
NX134 · NX121
NX133 · NX171
NX466 · NX171Travel Information
Compare train and bus for Derby to Manchester
Omio recommends booking the train as it is the most popular option from Derby to Manchester among Omio's users. If you are prioritising price take the bus with prices starting from $12. For those with little time consider booking a train which can get you there in 1h 40m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.0 - 0.1kg. The ticket price range depends on the travel mode: a bus costs an average of $12, and a train costs an average of $15.
Distance: 49 miles (80 km)
Compare bus with
| Bus | Most popular Train |
|---|---|
$23 Average price Cheapest | $37 Average price |
3h 14m Average total duration 2h 44m Onboard + 30m Additional time* | 2h 10m Average total duration Fastest 1h 40m Onboard + 30m Additional time* |
0.1 - 0.2kg CO2 emissions | 0.0 - 0.1kg CO2 emissions Lowest |
![]() Most popular bus company | ![]() Most popular train company |
Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Derby to Manchester Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator National Express | Departure Time 03:20AM | Arrival Time 08:20AM | Duration 5h00 | Departure days Tue, Wed | Cheapest price $40 |
Operator FlixBus | Departure Time 03:35AM | Arrival Time 11:20AM | Duration 7h45 | Departure days Tue, Wed | Cheapest price $20 |
Operator National Express | Departure Time 08:40AM | Arrival Time 01:15PM | Duration 4h35 | Departure days Tue, Wed | Cheapest price $18 |
Operator FlixBus | Departure Time 11:55AM | Arrival Time 05:20PM | Duration 5h25 | Departure days Tue, Wed | Cheapest price $21 |
Operator National Express | Departure Time 02:40PM | Arrival Time 07:10PM | Duration 4h30 | Departure days Tue, Wed | Cheapest price $23 |
Operator National Express | Departure Time 02:45PM | Arrival Time 07:25PM | Duration 4h40 | Departure days Tue, Wed | Cheapest price $26 |
Operator National Express | Departure Time 08:40PM | Arrival Time 12:50AM | Duration 4h10 | Departure days Tue, Wed | Cheapest price $19 |
Live departures
Derby to Manchester bus times
The table below shows live departures for Derby to Manchester buses for today, Tuesday, March 3. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
NX134 · NX121 | 8:40 AM Derby, Bus Station | 4h35 | 1:15 PM Manchester, Coach Station | 1 transfer | |
FlixBus · FlixBus | 11:55 AM Derby, Bus Station | 5h25 | 5:20 PM Manchester, Shudehill Interchange | 1 transfer | |
NX133 · NX120 | On time 2:40 PM Derby, Bus Station | 4h30 | 7:10 PM Manchester, Coach Station | 1 transfer | |
NX133 · NX171 | 2:45 PM Derby, Bus Station | 4h40 | 7:25 PM Manchester, Coach Station | 1 transfer | |
NX134 · NX171 | 8:40 PM Derby, Bus Station | 4h10 | 12:50 AM Manchester, Coach Station | 1 transfer | |
NX466 · NX171 | 3:20 AM Derby, Bus Station | 5h00 | 8:20 AM Manchester, Coach Station | 1 transfer | |
FlixBus · FlixBus | 3:35 AM Derby, Bus Station | 7h45 | 11:20 AM Manchester, Shudehill Interchange | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Derby to Manchester by train or bus
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Mar 04
Mar 05
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Mar 08
Mar 09
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Mar 11
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Mar 16
Mar 17
Why should you book Derby to Manchester buses with Omio?
Why book with Omio vs National Express?
- Compare with other providers: On Omio, you can not only buy tickets for National Express, but also compare tickets for the likes of FlixBus or Megabus to find the best option for your trip from Derby to Manchester.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare National Express with all available travel options, which are train and bus to ensure you get the best deal for traveling from Derby to Manchester.
Why book with Omio over Wanderu or Trainline?
- Compare with other providers: On Omio, you can also compare tickets for the likes of FlixBus or Megabus to find the best option for your trip from Derby to Manchester.
- Multiple modes of transport: Omio allows you to compare travel options including train and bus to find the ideal travel option from Derby to Manchester.
Journey information
Overview: Bus from Derby to Manchester
Buses from Derby to Manchester run on average 5 times per day, taking around 2h 44m. Cheap bus tickets for this journey start at $12 (€10) if you book in advance.
The earliest bus runs at 00:09, the last at 22:30. The fastest bus covers the 49 miles (80 km) distance in 2h 37m.
Distance 49 miles (80 km) |
Average bus duration 2h 44m |
Cheapest ticket price $12 (€10) |
Buses per day 5 |
Fastest bus 2h 37m |
First bus 00:09 |
Last bus 22:30 |
Bus providers: National Express, FlixBus, Megabus from Derby to ManchesterYou can travel by bus between Derby to Manchester with National Express, FlixBus, Megabus for as low as $12 (€10). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
National Express
Megabus
FAQs: Bus from Derby to Manchester
Find answers to the most common questions about traveling from Derby to Manchester by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Manchester, this guide helps you travel smarter and with confidence.

- Megabus
- Megabus is ADA-compliant and provides assistance to customers with disabilities, including those using wheelchairs or mobility scooters, and those with service animals.
- National Express
- Assistance
- Priority seating
- Accessible toilets.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Manchester Art Gallery, a public art museum housing an extensive collection of fine art and decorative pieces
- Science and Industry Museum, an interactive museum exploring Manchester's industrial heritage and scientific achievements
- Manchester Cathedral, a historic Gothic-style cathedral known for its stunning architecture and serene atmosphere
- The John Rylands Library, a neo-Gothic library with an impressive collection of rare books and manuscripts
- Castlefield, a historic area with Roman ruins and picturesque canals, perfect for a leisurely stroll.
- Old Trafford, the iconic football stadium and home to Manchester United, offering tours and a museum dedicated to the club's history
- The Northern Quarter, a vibrant district known for its independent shops, cafes, and street art
- Visit the Manchester Opera House for a captivating performance
- Explore the vibrant nightlife at Deansgate Locks, a popular area with bars and clubs
- Enjoy a relaxing day at Heaton Park, one of the largest municipal parks in Europe, offering beautiful landscapes and recreational activities.
- Megabus
- Megabus reservations cannot be canceled or refunded, but they can be traded in for another journey up to 3 hours before your original scheduled departure for a fee.
- National Express
- You can cancel your ticket up to 24 hours before departure for a refund minus a cancellation fee. Changes can be up to 24 hours before departure for a fee.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Megabus
- One piece of luggage is included per passenger reservation. For guidance, a piece of luggage must not exceed 62 inches (length + width + height) and should not weigh more than 50 pounds (23kg).
- National Express
- Two medium-sized suitcases up to 20kg each and one small piece of hand luggage.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Megabus
- Additional luggage can be purchased by buying an additional travel ticket in advance or by adding up to two additional pieces when booking for a fee.
- National Express
- 10€ per additional bag.
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Popular bus stations from Derby to Manchester
- 06:00-22:00
- Free Wi-Fi
- Café at the Station (in the station)
- Fast Food Express (in the station).
- Available outside the main entrance.
- Ramps, assistance
- Available in the station.
- Bus: 50, 192, 201, 203, 205, 219, 255, 256 Train: Manchester Piccadilly Metro: Piccadilly Gardens
- 00:00-23:59
- Free Wi-Fi
- Burger King (in the station)
- Giraffe (in the station).
- Available outside the terminal, with several companies offering services.
- Elevators, ramps, assistance
- Available in the station.
- Bus: 43, 103 Train: Manchester Airport
- 05:00-23:30
- Free Wi-Fi
- Available outside the interchange.
- Elevators, ramps
- Available in the station.
- Bus: 42, 43, 135 Tram: Metrolink
Most popular bus connections from Derby
More options for your journey from Derby to Manchester
Here are some other resources that might have the information you need

