- Must visit
California Academy of Sciences
Renowned science museum with rainforest dome, aquarium, and planetarium. Interactive exhibits make it a standout for all ages.
Buses from Santa Clarita, CA to San Francisco, CA run on average 3 times per day, taking around 9h 2m. Cheap bus tickets for this journey start at €65 if you book in advance.
There are 1 buses per day. The earliest bus runs at 00:25, the last at 23:35. The fastest bus covers the 318 miles (513 km) distance in 7h 15m.
Distance 318 miles (513 km) |
Average bus duration 9h 2m |
Cheapest ticket price €65 |
Buses per day 3 |
Direct buses 1 |
Fastest bus 7h 15m |
First bus 12:25 AM |
Last bus 11:35 PM |
Cheapest Month Feb |
Cheapest Day Thu |
High Season Jul - Sep |
Low Season Oct - Dec |
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Santa Clarita, CA to San Francisco, CA.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 12:30AM | Arrival Time 12:55PM | Duration 12h25 | Departure days Sun | Cheapest price €74 |
Operator Greyhound | Departure Time 06:35AM | Arrival Time 02:15PM | Duration 7h40 | Departure days Tue, Sun | Cheapest price €60 |
Operator Greyhound | Departure Time 07:25AM | Arrival Time 07:25PM | Duration 12h00 | Departure days Tue | Cheapest price €65 |
Operator Greyhound | Departure Time 07:35AM | Arrival Time 03:15PM | Duration 7h40 | Departure days Tue | Cheapest price €60 |
Operator Greyhound | Departure Time 08:25AM | Arrival Time 08:25PM | Duration 12h00 | Departure days Sat | Cheapest price €71 |
Operator FlixBus | Departure Time 09:45AM | Arrival Time 05:55PM | Duration 8h10 | Departure days Sun | Cheapest price €103 |
Operator Greyhound | Departure Time 12:35PM | Arrival Time 08:45PM | Duration 8h10 | Departure days Sun | Cheapest price €75 |
Operator FlixBus | Departure Time 04:30PM | Arrival Time 07:05AM | Duration 14h35 | Departure days Thu | Cheapest price €38 |
Operator FlixBus | Departure Time 04:40PM | Arrival Time 12:35AM | Duration 7h55 | Departure days Tue | Cheapest price €92 |
Operator FlixBus | Departure Time 09:00PM | Arrival Time 08:30AM | Duration 11h30 | Departure days Sun | Cheapest price €93 |
Operator Greyhound | Departure Time 11:55PM | Arrival Time 07:10AM | Duration 7h15 | Departure days Sun | Cheapest price €100 |
The table below shows live departures for Santa Clarita, CA to San Francisco, CA buses for today, Tuesday, November 3. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 7:25 AM Santa Clarita, CA | 12h00 | 7:25 PM San Francisco, CA | 0 transfersDirect | |
![]() | 4:40 PM Santa Clarita, CA | 7h55 | 12:35 AM San Francisco, CA | 0 transfersDirect | |
This is the last bus of the day. | |||||
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Discover the best of San Francisco, CA — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect San Francisco, CA trip today.
Renowned science museum with rainforest dome, aquarium, and planetarium. Interactive exhibits make it a standout for all ages.
Major fine arts museum in Golden Gate Park with American art, textiles, and a panoramic tower. A classic cultural highlight.
Leading modern and contemporary art museum with landmark architecture and strong global collections. Essential for art-focused visitors.
Large urban park with gardens, lakes, museums, and trails. It is a must for relaxing, walking, and seeing several major attractions.
Steeply curving block lined with flowers and grand homes. This famous street offers classic photos and a quintessential San Francisco scene.
Popular waterfront promenade with bay views, piers, and ferries. Great for walking, people-watching, and connecting to nearby sights.
A crusty loaf with a tangy flavor shaped by the city’s historic wild yeast culture. It is one of San Francisco’s most iconic foods.
Fresh local Dungeness crab, often cracked and served simply or in cioppino. It is a Bay Area seasonal specialty tied to the fishing waterfront.
A tomato-based seafood stew created by Italian American fishermen in North Beach. It is a classic San Francisco dish built from the day’s catch.
Celebrated fine dining destination known for inventive tasting menus and polished service in an elegant, intimate setting.
Historic North Beach seafood house famous for cioppino, crab, and old-school San Francisco waterfront charm.
Legendary Mission taqueria known for large Mission-style burritos and a lively, no-frills local atmosphere.
Very high hotel, dining, and transport costs make San Francisco pricier than most US cities and many major tourist destinations.
Tip 18-20% at restaurants, 15-20% for taxis, and round up or tip $1 at cafes for good service.
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in San Francisco, CA.
Find answers to the most common questions about traveling from Santa Clarita, CA to San Francisco, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at San Francisco, CA, this guide helps you travel smarter and with confidence.

Most Santa Clarita, CA to San Francisco, CA buses use the to San Francisco, Transit Center Bay 29 station pair, with some services arriving at San Francisco, Townsend Street / 5th Street. Use this guide to compare Santa Clarita, CA and San Francisco, CA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
San Francisco, Transit Center Bay 29 is 2 km from San Francisco city centre. Public transport options include:
San Francisco, Transit Center Bay 29 has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at San Francisco, Transit Center Bay 29. ATMs are available at San Francisco, Transit Center Bay 29.
Ticket office support is available at San Francisco, Transit Center Bay 29.
Available at San Francisco, Transit Center Bay 29: Parking, Taxis, WC.
Accessibility facilities are available at San Francisco, Transit Center Bay 29: Wheelchair accessible areas present.
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