- Recommended
Hilliard Art Museum
Regional history museum covering Acadiana culture, industry, and daily life through artifacts and changing exhibitions.
Buses from Columbus, OH to Lafayette, LA run on average 10 times per day, taking around 29h 52m. Cheap bus tickets for this journey start at €80 if you book in advance.
The earliest bus runs at 02:00, the last at 23:50. The fastest bus covers the 843 miles (1357 km) distance in 25h 5m.
Plan this route
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Columbus, OH to Lafayette, LA.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 03:30AM | Arrival Time 10:15PM | Duration 42h45 | Departure days Sun | Cheapest price €179 |
Operator FlixBus | Departure Time 04:30AM | Arrival Time 02:15PM | Duration 33h45 | Departure days Mon | Cheapest price €182 |
Operator Greyhound | Departure Time 04:50AM | Arrival Time 12:55PM | Duration 32h05 | Departure days Mon | Cheapest price €212 |
Operator Greyhound | Departure Time 02:45PM | Arrival Time 06:05PM | Duration 27h20 | Departure days Wed | Cheapest price €210 |
Operator Greyhound | Departure Time 06:30PM | Arrival Time 02:10AM | Duration 31h40 | Departure days Fri, Sat | Cheapest price €157 |
Buses from Columbus, OH to Lafayette, LA with Greyhound and FlixBus. Overnight buses available on this route with Greyhound and FlixBus. Use the details below to compare onboard facilities.
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
Discover the best of Lafayette, LA — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Lafayette, LA trip today.
Regional history museum covering Acadiana culture, industry, and daily life through artifacts and changing exhibitions.
University art museum with strong Louisiana-focused exhibitions, modern galleries, and a compact but rewarding collection.
Hands-on children’s museum downtown with interactive exhibits focused on play, learning, and family visits.
Walkable downtown district with local shops, murals, live music venues, and regular public events in the city center.
Large urban park with walking paths, ponds, sports areas, and broad green space popular for everyday local recreation.
Nature area with boardwalks and trails through cypress-tupelo wetlands, offering easy wildlife viewing near the city.
A rice-and-gravy plate topped with a breaded steak smothered in brown gravy, usually served with sides. A beloved Acadiana comfort food with strong Cajun roots.
A rich stew built from a dark roux with seafood or meats, served over rice. It is one of the signature dishes of Cajun and Creole south Louisiana cooking.
A deeply seasoned rice dish traditionally made with pork liver, rice, and spices, often stuffed into casing or served as a rice dressing. Distinctive to Cajun country.
Long-running spot famous for boudin, cracklins, and plate lunches. A practical stop for traditional Cajun meats and regional specialties.
Refined restaurant serving contemporary Louisiana cooking with local ingredients in an elegant but relaxed downtown atmosphere.
Well-known Cajun breakfast and lunch café serving boudin, biscuits, and hearty local comfort food in a friendly casual space.
Moderate for U.S. travelers. Hotels and dining are usually cheaper than major U.S. cities, but car use and limited transit can add to daily costs.
Tip 15-20% at restaurants, $1-2 per drink at bars, and 10-15% for taxis. Cafes often have tip jars or a card prompt.
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Lafayette, LA.
Find answers to the most common questions about traveling from Columbus, OH to Lafayette, LA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Lafayette, LA, this guide helps you travel smarter and with confidence.

Most Columbus, OH to Lafayette, LA buses use the Columbus, E Mound St (Akili Christian High School) to Lafayette, Lee Ave (Greyhound Bus Station) station pair, with some services arriving at Lafayette, TA Travel center. Use this guide to compare Columbus, OH and Lafayette, LA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Columbus, E Town St (Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Columbus, E Town St (Bus Station). ATMs are available at Columbus, E Town St (Bus Station).
Ticket office support is available at Columbus, E Town St (Bus Station).
Available at Columbus, E Town St (Bus Station): Parking, Taxis, WC.
Accessibility facilities are available at Columbus, E Town St (Bus Station): Wheelchair accessible bus platforms.
Columbus, E Mound St (Akili Christian High School) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Columbus, E Mound St (Akili Christian High School). ATMs are available at Columbus, E Mound St (Akili Christian High School).
Ticket office support is available at Columbus, E Mound St (Akili Christian High School).
Available at Columbus, E Mound St (Akili Christian High School): Parking, Taxis, WC.
Accessibility facilities are available at Columbus, E Mound St (Akili Christian High School): Wheelchair accessible buses available.
Lafayette, Lee Ave (Greyhound Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Lafayette, Lee Ave (Greyhound Bus Station). ATMs are available at Lafayette, Lee Ave (Greyhound Bus Station).
Ticket office support is available at Lafayette, Lee Ave (Greyhound Bus Station).
Available at Lafayette, Lee Ave (Greyhound Bus Station): Parking, Taxis, WC.
Accessibility facilities are available at Lafayette, Lee Ave (Greyhound Bus Station): Ramp access available.
Lafayette, TA Travel center is 3 km from Lafayette city centre. Public transport options include:
Lafayette, TA Travel center has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: There is a fast-food restaurant at the station.
Free Wi-Fi is available in the waiting area. ATMs are an ATM is available near the main entrance.
Ticket office support is available at Lafayette, TA Travel center.
Available at Lafayette, TA Travel center: Parking, Taxis, WC.
Accessibility facilities are available at Lafayette, TA Travel center: The station is wheelchair accessible.
Check bus stations information for Columbus, OH and Lafayette, LA, including where buses depart and arrive on this route.