The cheapest and fastest buses from Mississauga, ON to Chicago, IL
Cheapest price
$161
Average price
$161
Fastest journey
19 h 40 m
Average duration
19 h 40 m
Buses per day
1
Distance
682 km
The best way to find a cheap bus ticket from Mississauga, ON to Chicago, IL is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Mississauga, ON to Chicago, IL will cost around $161 if you buy it on the day, but the cheapest tickets can be found for only $161.
It's difficult to get from Mississauga, ON to Chicago, IL without transferring at least 2 times.


Travel Information
Compare bus for Mississauga, ON to Chicago, IL
Omio recommends booking the bus as it is the most popular option from Mississauga, ON to Chicago, IL among Omio's users. If you are prioritising price take the bus with prices starting from €132. For those with little time consider booking a flight which can get you there in 1h 50m. The ticket price range depends on the travel mode: a bus costs an average of €132, and a flight costs an average of €224.
Distance: 423 miles (682 km)
Compare bus with
Most popular Bus | Flight |
|---|---|
€132 Average price Cheapest | €224 Average price |
13h 10m Average total duration 12h 40m Onboard + 30m Additional time* | 4h 50m Average total duration Fastest 1h 50m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options |
Live departures
Mississauga, ON to Chicago, IL bus times
The table below shows live departures for Mississauga, ON to Chicago, IL buses for tomorrow, Thursday, November 20. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 6:15 PM Mississauga, ON | 19h40 | 1:55 PM Chicago, IL | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Mississauga, ON to Chicago, IL by bus
Compare bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Nov 20
Nov 21
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Nov 26
Journey information
Overview: Bus from Mississauga, ON to Chicago, IL
Buses from Mississauga, ON to Chicago, IL run on average 1 times per day, taking around 12h 40m. Cheap bus tickets for this journey start at $162 (€132) if you book in advance.
The earliest bus runs at 06:55, the last at 23:15. The fastest bus covers the 423 miles (682 km) distance in 19h 35m.
Distance 423 miles (682 km) |
Average bus duration 12h 40m |
Cheapest ticket price $162 (€132) |
Buses per day 1 |
Fastest bus 19h 35m |
First bus 06:55 |
Last bus 23:15 |
Bus providers: FlixBus, GO Transit from Mississauga, ON to Chicago, ILYou can travel by bus between Mississauga, ON to Chicago, IL with FlixBus, GO Transit for as low as $162 (€132). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
GO Transit
FAQs: Bus from Mississauga, ON to Chicago, IL
Find answers to the most common questions about traveling from Mississauga, ON to Chicago, IL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Chicago, IL, this guide helps you travel smarter and with confidence.

- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Millennium Park, a public park known for its modern art installations and the iconic Cloud Gate sculpture
- Art Institute of Chicago, a renowned museum housing an extensive collection of art from around the world
- Navy Pier, a popular entertainment destination featuring rides, restaurants, and lakefront views
- Willis Tower Skydeck, an observation deck offering panoramic views of the city from one of the tallest buildings in the Western Hemisphere
- Field Museum, a natural history museum with vast exhibits including the famous T. Rex skeleton, Sue.
- Museum of Science and Industry, an interactive museum featuring exhibits on science, technology, and industry
- Explore the vibrant neighborhoods of Chicago, such as Wicker Park and Lincoln Park, known for their unique shops and eateries
- Take a river cruise to see the city's iconic architecture from a different perspective
- Attend a live performance at the historic Chicago Theatre
- Enjoy a day at Lincoln Park Zoo, one of the oldest zoos in the U. S. Offering free admission.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
To find the cheapest bus tickets for your trip from Mississauga, ON to Chicago, IL, follow these tips:
Start your search now and compare ticket prices to find the best deal!
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- Guide dogs travel for free.
popular bus stations
Popular bus stations from Mississauga, ON to Chicago, IL
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