The cheapest and fastest buses from Mission Viejo, CA to San Francisco, CA
Cheapest price
$69
Average price
$69
Fastest journey
11 h 53 m
Average duration
11 h 53 m
Buses per day
1
Distance
632 km
The best way to find a cheap bus ticket from Mission Viejo, CA to San Francisco, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Mission Viejo, CA to San Francisco, CA will cost around $69 if you buy it on the day, but the cheapest tickets can be found for only $69.
Of the 1 buses that leave Mission Viejo, CA for San Francisco, CA on Fri, May 08, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Fri, May 08 the direct buses cover the 632 km distance in an average of 11 h 53 m but if you time it right, some buses will get you there in just 11 h 53 m .
On Fri, May 08 the slowest buses will take 11 h 53 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
1:52 AM11h53Mission Viejo, CA1:45 PMSan Francisco, CA$691One-way0 transfers
1:52 AM11h53Mission Viejo, CA1:45 PMSan Francisco, CA$691One-way0 transfers
Travel Information
Compare bus, train, and flight for Mission Viejo, CA to San Francisco, CA
Omio recommends booking the flight as it is the most popular option from Mission Viejo, CA to San Francisco, CA among Omio's users. If you are prioritising price take the bus with prices starting from $68. For those with little time consider booking a flight which can get you there in 1h 32m. The ticket price range depends on the travel mode: a bus costs an average of $68, and a flight costs an average of $162.
Distance: 392 miles (632 km)
Compare bus with
| Bus | Most popular Flight | Train |
|---|---|---|
$72 Average price Cheapest | $234 Average price | $73 Average price |
12h 6m Average total duration 11h 36m Onboard + 30m Additional time* | 4h 32m Average total duration Fastest 1h 32m Onboard + 3h 0m Additional time* | 12h 46m Average total duration 12h 16m Onboard + 30m Additional time* |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Mission Viejo, CA to San Francisco, CA:
A bus is $1 (€0.92) less than a train for this route with tickets for a train from Mission Viejo, CA to San Francisco, CA costing on average $73 (€58).
A bus is $162 (€129) less than a flight for this route with tickets for a flight from Mission Viejo, CA to San Francisco, CA costing on average $234 (€186).
Other travel options to San Francisco, CA take longer:
Bus takes on average 11h 36m.
Train takes on average 12h 16m.
Mission Viejo, CA to San Francisco, CA Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Amtrak | Departure Time 05:49AM | Arrival Time 05:25PM | Duration 11h36 | Departure days Wed | Cheapest price $81 |
Operator Greyhound | Departure Time 08:45AM | Arrival Time 10:05PM | Duration 13h20 | Departure days Wed | Cheapest price $158 |
Operator Amtrak | Departure Time 09:52AM | Arrival Time 10:05PM | Duration 12h13 | Departure days Wed | Cheapest price $81 |
Operator Amtrak | Departure Time 05:52PM | Arrival Time 06:05AM | Duration 12h13 | Departure days Wed | Cheapest price $81 |
Operator Greyhound | Departure Time 09:20PM | Arrival Time 07:15AM | Duration 9h55 | Departure days Wed | Cheapest price $186 |
Operator Greyhound | Departure Time 09:40PM | Arrival Time 07:15AM | Duration 9h35 | Departure days Wed | Cheapest price $186 |
Live departures
Mission Viejo, CA to San Francisco, CA bus times
The table below shows live departures for Mission Viejo, CA to San Francisco, CA buses for today, Wednesday, May 6. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
785 Pacific Surfliner · 4785 AMTRAK | 5:52 PM Irvine Transportation Center, Irvine, CA | 12h13 | 6:05 AM Emeryville station, Emeryville, CA | 1 transfer | |
| Thursday, May 7 | |||||
![]() | 1:52 AM Mission Viejo, CA | 11h53 | 1:45 PM San Francisco, CA | 0 transfersDirect | |
| Wednesday, May 6 | |||||
![]() | 9:20 PM Santa Ana, E Santa Ana Blvd (Train Station) | 9h55 | 7:15 AM San Francisco, Transit Center Bay 29 | 0 transfersDirect | |
![]() | 9:40 PM Anaheim, Regional Transportation Intermodal Center (ARTIC) | 9h35 | 7:15 AM San Francisco, Transit Center Bay 29 | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Mission Viejo, CA to San Francisco, CA by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
May 07
May 08
May 09
May 10
May 11
May 12
May 13
Journey information
Overview: Bus from Mission Viejo, CA to San Francisco, CA
Buses from Mission Viejo, CA to San Francisco, CA run on average 27 times per day, taking around 11h 36m. Cheap bus tickets for this journey start at $68 (€54) if you book in advance.
There are 3 buses per day. The earliest bus runs at 04:55, the last at 23:25. The fastest bus covers the 392 miles (632 km) distance in 11h 48m.
Distance 392 miles (632 km) |
Average bus duration 11h 36m |
Cheapest ticket price $68 (€54) |
Buses per day 27 |
Direct buses 3 |
Fastest bus 11h 48m |
First bus 4:55 AM |
Last bus 11:25 PM |
Cheapest Month Dec |
Cheapest Day Wed |
High Season Jan - Mar |
Low Season Oct - Dec |
Bus providers: Amtrak from Mission Viejo, CA to San Francisco, CAYou can travel by bus between Mission Viejo, CA to San Francisco, CA with Amtrak for as low as $68 (€54). When you search for schedules and tickets, Omio will show you the best journey
Amtrak
FAQs: Bus from Mission Viejo, CA to San Francisco, CA
Find answers to the most common questions about traveling from Mission Viejo, CA to San Francisco, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at San Francisco, CA, this guide helps you travel smarter and with confidence.

- Amtrak
- Wheelchair spaces, accessible restrooms, Red Cap assistance service, accessible platforms and stations
- Golden Gate Bridge, an iconic suspension bridge offering panoramic views of the San Francisco Bay
- Alcatraz Island, a historic site featuring the infamous former prison and informative audio tours
- Fisherman's Wharf, a bustling waterfront area known for seafood, shops, and sea lions
- Golden Gate Park, a large urban park with gardens, museums, and recreational activities
- Chinatown, the oldest and one of the largest Chinatowns in North America, offering vibrant culture and cuisine.
- Ride a cable car through the steep streets of San Francisco for a classic city experience
- Explore the vibrant murals and street art in the Mission District
- Visit the Exploratorium, an interactive science museum perfect for all ages
- Take a scenic walk along the Embarcadero, offering views of the Bay Bridge and access to the Ferry Building Marketplace
- Enjoy a wine tasting tour in nearby Napa Valley, a short drive from the city.
- Amtrak
- Cancellation policies depend on ticket type and timing
- Amtrak
- 2 personal items and 2 carry-on bags included free
- Amtrak
- Small pets under 20 pounds allowed for $26 fee. Must be in carrier. Service animals travel free
popular bus stations
Popular bus stations from Mission Viejo, CA to San Francisco, CA
More options for your journey from Mission Viejo, CA to San Francisco, CA
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