The cheapest and fastest buses from Milan Centrale to Florence Santa Maria Novella
Cheapest price
$12
Average price
$25
Fastest journey
3 h 55 m
Average duration
4 h 9 m
Buses per day
23
Distance
250 km
The best way to find a cheap bus ticket from Milan Centrale to Florence Santa Maria Novella is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Milan Centrale to Florence Santa Maria Novella will cost around $25 if you buy it on the day, but the cheapest tickets can be found for only $12.
Of the 23 buses that leave Milan Centrale for Florence Santa Maria Novella on Mon, Aug 03, 18 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Mon, Aug 03 the direct buses cover the 250 km distance in an average of 4 h 9 m but if you time it right, some buses will get you there in just 3 h 55 m .
On Mon, Aug 03 the slowest buses will take 4 h 15 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
947636:25 AM4h20Milano, Autostazione Lampugnano10:45 AMScandicci, Villa Costanza (Florence)$121One-way0 transfers
34914:00 PM4h25Milano, Autostazione Lampugnano8:25 PMScandicci, Villa Costanza (Florence)$121One-way0 transfers
2213 · 24137:20 PM5h50Milano, Autostazione Lampugnano1:10 AMScandicci, Villa Costanza (Florence)$131One-way1 transfer
2213 · 27718:05 PM5h30Milano, San Donato - Settore B (Viale Giuseppe Impastato)1:35 AMScandicci, Villa Costanza (Florence)$131One-way1 transfer
2213 · 27717:20 PM6h15Milano, Autostazione Lampugnano1:35 AMScandicci, Villa Costanza (Florence)$131One-way1 transfer
388712:30 AM3h55Milano, San Donato - Settore B (Viale Giuseppe Impastato)4:25 AMScandicci, Villa Costanza (Florence)$311One-way0 transfers
0559:05 PM4h10Milano, San Donato - Settore B (Viale Giuseppe Impastato)1:15 AMScandicci, Villa Costanza (Florence)$581One-way0 transfers
24139:00 PM4h10Milano, San Donato - Settore B (Viale Giuseppe Impastato)1:10 AMScandicci, Villa Costanza (Florence)$131One-way0 transfers
38031:35 PM4h15Milano, San Donato - Settore B (Viale Giuseppe Impastato)5:50 PMScandicci, Villa Costanza (Florence)$181One-way0 transfers
24098:00 AM4h15Milano, San Donato - Settore B (Viale Giuseppe Impastato)12:15 PMScandicci, Villa Costanza (Florence)$151One-way0 transfers
Travel Information
Compare train, bus, and flight for Milan Centrale to Florence Santa Maria Novella
Omio recommends booking the train as it is the most popular option from Milan Centrale to Florence Santa Maria Novella among Omio's users. If you are prioritising price take the bus with prices starting from $11. For those with little time consider booking a train which can get you there in 3h 58m. The ticket price range depends on the travel mode: a bus costs an average of $11, and a flight costs an average of $168.
Distance: 155 miles (250 km)
Compare bus with
| Bus | Most popular Train | Flight | Driving |
|---|---|---|---|
$22 Average price Cheapest | $50 Average price | $176 Average price | $90 Average price (fuel + tolls) |
4h 32m Average total duration 4h 2m Onboard + 30m Additional time* | 4h 28m Average total duration Fastest 3h 58m Onboard + 30m Additional time* | 12h 59m Average total duration 9h 59m Onboard + 3h 0m Additional time* | 3h 26m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Milan Centrale to Florence Santa Maria Novella:
A bus is $27 (€22) less than a train for this route with tickets for a train from Milan Centrale to Florence Santa Maria Novella costing on average $50 (€40).
A bus is $154 (€125) less than a flight for this route with tickets for a flight from Milan Centrale to Florence Santa Maria Novella costing on average $176 (€143).
Other travel options to Florence Santa Maria Novella take longer:
Bus takes on average 4h 2m.
Flight takes on average 9h 59m.
Tickets start at around $22 (€18) compared to roughly $90 (€73) in fuel and tolls — a saving of about $68 (€55). The journey takes 4h 2m versus 3h 26m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by FlixBus, Itabus, BlaBlaCar Bus, BlaBlaCar, Calanda Viaggi, Infobus, Marino Autolinee.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
Milan Centrale to Florence Santa Maria Novella Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Itabus | Departure Time 12:30AM | Arrival Time 04:25AM | Duration 3h55 | Departure days Mon, Tue, Wed, Thu, Fri, Sat | Cheapest price $21 |
Operator BlaBlaCar | Departure Time 03:15AM | Arrival Time 06:20AM | Duration 3h05 | Departure days Tue | Cheapest price $24 |
Operator BlaBlaCar | Departure Time 05:00AM | Arrival Time 08:20AM | Duration 3h20 | Departure days Mon, Sat | Cheapest price $21 |
Operator BlaBlaCar | Departure Time 05:15AM | Arrival Time 09:00AM | Duration 3h45 | Departure days Thu | Cheapest price $26 |
Operator BlaBlaCar | Departure Time 05:30AM | Arrival Time 08:40AM | Duration 3h10 | Departure days Wed | Cheapest price $31 |
Operator BlaBlaCar Bus | Departure Time 06:25AM | Arrival Time 10:45AM | Duration 4h20 | Departure days Mon, Tue, Wed, Thu, Fri, Sat | Cheapest price $10 |
Operator BlaBlaCar | Departure Time 07:00AM | Arrival Time 10:30AM | Duration 3h30 | Departure days Sat | Cheapest price $20 |
Operator BlaBlaCar | Departure Time 07:30AM | Arrival Time 10:50AM | Duration 3h20 | Departure days Wed | Cheapest price $29 |
Operator BlaBlaCar | Departure Time 08:00AM | Arrival Time 11:10AM | Duration 3h10 | Departure days Mon, Tue | Cheapest price $18 |
Operator Itabus | Departure Time 08:00AM | Arrival Time 12:15PM | Duration 4h15 | Departure days Mon, Tue, Wed, Thu, Fri, Sat | Cheapest price $12 |
Operator BlaBlaCar | Departure Time 08:20AM | Arrival Time 11:20AM | Duration 3h00 | Departure days Tue, Sat | Cheapest price $21 |
Operator BlaBlaCar | Departure Time 09:00AM | Arrival Time 01:00PM | Duration 4h00 | Departure days Mon, Wed | Cheapest price $23 |
Operator BlaBlaCar | Departure Time 09:30AM | Arrival Time 01:50PM | Duration 4h20 | Departure days Fri, Sat | Cheapest price $18 |
Operator BlaBlaCar | Departure Time 10:00AM | Arrival Time 01:00PM | Duration 3h00 | Departure days Thu, Fri, Sat | Cheapest price $20 |
Operator BlaBlaCar | Departure Time 10:30AM | Arrival Time 02:10PM | Duration 3h40 | Departure days Mon | Cheapest price $23 |
Operator Itabus | Departure Time 10:40AM | Arrival Time 03:20PM | Duration 4h40 | Departure days Mon, Tue, Wed, Thu, Fri, Sat | Cheapest price $12 |
Operator Itabus | Departure Time 12:50PM | Arrival Time 05:50PM | Duration 5h00 | Departure days Mon, Tue, Wed, Thu, Fri, Sat | Cheapest price $12 |
Operator Itabus | Departure Time 01:35PM | Arrival Time 05:50PM | Duration 4h15 | Departure days Mon, Tue, Wed, Thu, Fri, Sat | Cheapest price $12 |
Operator BlaBlaCar | Departure Time 01:50PM | Arrival Time 05:00PM | Duration 3h10 | Departure days Wed | Cheapest price $31 |
Operator BlaBlaCar | Departure Time 03:15PM | Arrival Time 06:45PM | Duration 3h30 | Departure days Fri | Cheapest price $18 |
Operator BlaBlaCar | Departure Time 03:30PM | Arrival Time 06:50PM | Duration 3h20 | Departure days Thu | Cheapest price $28 |
Operator BlaBlaCar | Departure Time 04:00PM | Arrival Time 07:10PM | Duration 3h10 | Departure days Tue, Sun | Cheapest price $26 |
Operator Itabus | Departure Time 04:00PM | Arrival Time 08:25PM | Duration 4h25 | Departure days Everyday | Cheapest price $12 |
Operator BlaBlaCar | Departure Time 05:00PM | Arrival Time 08:10PM | Duration 3h10 | Departure days Mon | Cheapest price $21 |
Operator FlixBus | Departure Time 05:00PM | Arrival Time 11:00PM | Duration 6h00 | Departure days Everyday | Cheapest price $28 |
Operator BlaBlaCar | Departure Time 05:20PM | Arrival Time 08:10PM | Duration 2h50 | Departure days Tue | Cheapest price $24 |
Operator BlaBlaCar | Departure Time 06:00PM | Arrival Time 09:40PM | Duration 3h40 | Departure days Wed, Fri, Sun | Cheapest price $23 |
Operator BlaBlaCar | Departure Time 07:20PM | Arrival Time 10:50PM | Duration 3h30 | Departure days Sun | Cheapest price $37 |
Operator Itabus | Departure Time 07:20PM | Arrival Time 01:10AM | Duration 5h50 | Departure days Mon, Tue, Wed, Thu, Sat, Sun | Cheapest price $13 |
Operator BlaBlaCar | Departure Time 08:00PM | Arrival Time 11:40PM | Duration 3h40 | Departure days Thu, Fri, Sat | Cheapest price $21 |
Operator Itabus | Departure Time 08:05PM | Arrival Time 01:35AM | Duration 5h30 | Departure days Mon, Thu, Sat, Sun | Cheapest price $13 |
Operator Itabus | Departure Time 08:25PM | Arrival Time 02:45AM | Duration 6h20 | Departure days Everyday | Cheapest price $12 |
Operator Marino Autolinee | Departure Time 08:25PM | Arrival Time 01:15AM | Duration 4h50 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price $53 |
Operator FlixBus | Departure Time 08:35PM | Arrival Time 01:00AM | Duration 4h25 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price $14 |
Operator Itabus | Departure Time 09:00PM | Arrival Time 01:10AM | Duration 4h10 | Departure days Everyday | Cheapest price $13 |
Operator Itabus | Departure Time 09:05PM | Arrival Time 03:10AM | Duration 6h05 | Departure days Mon, Sat, Sun | Cheapest price $38 |
Operator Marino Autolinee | Departure Time 09:05PM | Arrival Time 01:15AM | Duration 4h10 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price $52 |
Operator BlaBlaCar | Departure Time 09:30PM | Arrival Time 12:40AM | Duration 3h10 | Departure days Thu | Cheapest price $24 |
Operator Itabus | Departure Time 09:35PM | Arrival Time 02:05AM | Duration 4h30 | Departure days Everyday | Cheapest price $12 |
Operator FlixBus | Departure Time 10:00PM | Arrival Time 02:40AM | Duration 4h40 | Departure days Everyday | Cheapest price $16 |
Operator Itabus | Departure Time 10:30PM | Arrival Time 03:35AM | Duration 5h05 | Departure days Everyday | Cheapest price $25 |
Operator Itabus | Departure Time 10:45PM | Arrival Time 04:10AM | Duration 5h25 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $15 |
Operator Itabus | Departure Time 11:30PM | Arrival Time 04:10AM | Duration 4h40 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $15 |
Operator Itabus | Departure Time 11:50PM | Arrival Time 04:25AM | Duration 4h35 | Departure days Everyday | Cheapest price $21 |
Live departures
Milan Centrale to Florence Santa Maria Novella bus times
The table below shows live departures for Milan Centrale to Florence Santa Maria Novella buses for today, Sunday, August 2. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
3491 | 4:00 PM Milano, Autostazione Lampugnano | 4h25 | 8:25 PM Scandicci, Villa Costanza (Florence) | 0 transfersDirect | |
FlixBus · FlixBus | 5:00 PM Milano, Autostazione Lampugnano | 6h00 | 11:00 PM Firenze, Piazzale Montelungo | 1 transfer | |
2213 · 2771 | 7:20 PM Milano, Autostazione Lampugnano | 6h15 | 1:35 AM Scandicci, Villa Costanza (Florence) | 1 transfer | |
2213 · 2413 | 7:20 PM Milano, Autostazione Lampugnano | 5h50 | 1:10 AM Scandicci, Villa Costanza (Florence) | 1 transfer | |
2213 · 2771 | 8:05 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 5h30 | 1:35 AM Scandicci, Villa Costanza (Florence) | 1 transfer | |
055 | 8:25 PM Milano, Autostazione Lampugnano | 4h50 | 1:15 AM Scandicci, Villa Costanza (Florence) | 0 transfersDirect | |
3505 | 8:25 PM Milano, Autostazione Lampugnano | 6h20 | 2:45 AM Scandicci, Villa Costanza (Florence) | 0 transfersDirect | |
FlixBus | 8:35 PM Milano, Autostazione Lampugnano | 4h25 | 1:00 AM Firenze, Piazzale Montelungo | 0 transfersDirect | |
2413 | 9:00 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 4h10 | 1:10 AM Scandicci, Villa Costanza (Florence) | 0 transfersDirect | |
055 | 9:05 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 4h10 | 1:15 AM Scandicci, Villa Costanza (Florence) | 0 transfersDirect | |
2205 · 2701 | 9:05 PM Milano, Autostazione Lampugnano | 6h05 | 3:10 AM Scandicci, Villa Costanza (Florence) | 1 transfer | |
2421 | 9:35 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 4h30 | 2:05 AM Scandicci, Villa Costanza (Florence) | 0 transfersDirect | |
FlixBus | 10:00 PM Milano, Autostazione Lampugnano | 4h40 | 2:40 AM Firenze, Piazzale Montelungo | 0 transfersDirect | |
3897 | 10:30 PM Milano, Autostazione Lampugnano | 5h05 | 3:35 AM Scandicci, Villa Costanza (Florence) | 0 transfersDirect | |
2495 | 10:45 PM Milano, Autostazione Lampugnano | 5h25 | 4:10 AM Scandicci, Villa Costanza (Florence) | 0 transfersDirect | |
2495 | 11:30 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 4h40 | 4:10 AM Scandicci, Villa Costanza (Florence) | 0 transfersDirect | |
3887 | 11:50 PM Milano, Autostazione Lampugnano | 4h35 | 4:25 AM Scandicci, Villa Costanza (Florence) | 0 transfersDirect | |
| Monday, August 3 | |||||
3887 | 12:30 AM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 3h55 | 4:25 AM Scandicci, Villa Costanza (Florence) | 0 transfersDirect | |
94763 | 6:25 AM Milano, Autostazione Lampugnano | 4h20 | 10:45 AM Scandicci, Villa Costanza (Florence) | 0 transfersDirect | |
2409 | 8:00 AM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 4h15 | 12:15 PM Scandicci, Villa Costanza (Florence) | 0 transfersDirect | |
2125 | 10:40 AM Milano, Autostazione Lampugnano | 4h40 | 3:20 PM Scandicci, Villa Costanza (Florence) | 0 transfersDirect | |
3803 | 12:50 PM Milano, Autostazione Lampugnano | 5h00 | 5:50 PM Scandicci, Villa Costanza (Florence) | 0 transfersDirect | |
3803 | 1:35 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 4h15 | 5:50 PM Scandicci, Villa Costanza (Florence) | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Milan Centrale to Florence Santa Maria Novella by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Aug 03
Aug 04
Aug 05
Aug 06
Aug 07
Aug 08
Aug 09
Aug 10
Aug 11
Aug 12
Aug 13
Aug 14
Aug 15
Aug 16
Aug 17
Aug 18
Aug 19
Aug 20
Aug 21
Aug 22
Aug 23
Why should you book Milan Centrale to Florence Santa Maria Novella buses with Omio?
Why book with Omio vs FlixBus?
- Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of Itabus, BlaBlaCar Bus, Calanda Viaggi or Infobus to find the best option for your trip from Milan Centrale to Florence Santa Maria Novella.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Milan Centrale to Florence Santa Maria Novella.
Why book with Omio over Wanderu, Trainline or Checkmybus?
- Compare with other providers: On Omio, you can also compare tickets for the likes of Itabus, BlaBlaCar Bus, Calanda Viaggi or Infobus to find the best option for your trip from Milan Centrale to Florence Santa Maria Novella.
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Milan Centrale to Florence Santa Maria Novella.
Journey information
Overview: Bus from Milan Centrale to Florence Santa Maria Novella
Buses from Milan Centrale to Florence Santa Maria Novella run on average 29 times per day, taking around 4h 2m. Cheap bus tickets for this journey start at $11 (€9) if you book in advance.
There are 23 buses per day. The earliest bus runs at 04:25, the last at 21:40. The fastest bus covers the 155 miles (250 km) distance in 3h 15m.
Distance 155 miles (250 km) |
Average bus duration 4h 2m |
Cheapest ticket price $11 (€9) |
Buses per day 29 |
Direct buses 23 |
Fastest bus 3h 15m |
First bus 4:25 AM |
Last bus 9:40 PM |
Cheapest Month Nov |
Cheapest Day Mon |
High Season Apr - Jun |
Low Season Jan - Mar |
Busiest Day Mon |
Least Busy Day Sat |
Bus providers: FlixBus, Itabus, BlaBlaCar Bus, BlaBlaCar, Calanda Viaggi, Infobus, Marino Autolinee from Milan Centrale to Florence Santa Maria NovellaYou can travel by bus between Milan Centrale to Florence Santa Maria Novella with FlixBus, Itabus, BlaBlaCar Bus, BlaBlaCar, Calanda Viaggi, Infobus, Marino Autolinee for as low as $11 (€9). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Itabus
Infobus
Marino Autolinee
BlaBlaCar Bus
Calanda Viaggi
BlaBlaCar
FAQs: Bus from Milan Centrale to Florence Santa Maria Novella
Find answers to the most common questions about traveling from Milan Centrale to Florence Santa Maria Novella by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Florence Santa Maria Novella, this guide helps you travel smarter and with confidence.

- BlaBlaCar Bus
- Assistance
- Priority boarding
- Accessible seating options.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Itabus
- Assistance
- Dedicated seating areas
- Accessible restrooms.
- BlaBlaCar Bus
- You can cancel your ticket up to 30 minutes before departure for a refund in the form of a voucher.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Itabus
- You can cancel your ticket up to 24 hours before departure for a partial refund. Changes allowed for a fee.
- BlaBlaCar Bus
- One carry-on bag up to 7kg and one checked bag up to 20kg.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Itabus
- One carry-on bag up to 10kg and one checked bag up to 20kg.
- BlaBlaCar Bus
- Additional luggage can be purchased for a fee.
- FlixBus
- Additional luggage can be purchased for a fee.
- Itabus
- 5€ per additional bag.
- Infobus
- Small pets allowed in carriers
- larger pets may require a separate ticket.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
- Itabus
- Small pets allowed in carriers
- larger pets must be leashed and muzzled.
More options for your journey from Milan Centrale to Florence Santa Maria Novella
Here are some other resources that might have the information you need

