Florence Santa Maria Novella to Milan Centrale bus with FlixBus

Fri, Jun 19
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FlixBus
Itabus
BlaBlaCar
BlaBlaCar Bus
Marino Autolinee
2,000+ travel companies
FlixBus
Itabus
BlaBlaCar
BlaBlaCar Bus
Marino Autolinee
2,000+ travel companies
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The cheapest and fastest buses from Florence Santa Maria Novella to Milan Centrale

Showing times and prices for Jun 19

Cheapest price

$32

Average price

$60

Fastest journey

3 h 38 m

Average duration

4 h 12 m

Buses per day

25

Distance

250 km

Cheap tickets

The best way to find a cheap bus ticket from Florence Santa Maria Novella to Milan Centrale is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Florence Santa Maria Novella to Milan Centrale will cost around $60 if you buy it on the day, but the cheapest tickets can be found for only $32.

Fast buses

It's difficult to get from Florence Santa Maria Novella to Milan Centrale without transferring at least 2 times.

  • RegionaleRegionale 18488 · Regionale 17806+TrenitaliaBUS L580A
    6:03 AM9h14
    Florence Santa Maria Novella
    3:17 PMMilan Centrale
    $321One-way
    2 transfers
  • RegionaleRegionale 18502 · Regionale 17808+TrenitaliaBUS L580A
    7:09 AM8h08
    Florence Santa Maria Novella
    3:17 PMMilan Centrale
    $321One-way
    2 transfers
  • Italo8900+TrenitaliaBUS LP604
    7:39 AM9h01
    Florence Santa Maria Novella
    4:40 PMMilan Centrale
    $571One-way
    1 transfer
  • Italo9908+TrenitaliaBUS L580A
    8:25 AM6h52
    Florence Santa Maria Novella
    3:17 PMMilan Centrale
    $571One-way
    1 transfer
  • Italo9908+TrenitaliaBUS LP604
    8:25 AM8h15
    Florence Santa Maria Novella
    4:40 PMMilan Centrale
    $571One-way
    1 transfer

Travel Information

Compare bus, train, and flight for Florence Santa Maria Novella to Milan Centrale

Omio recommends booking the train as it is the most popular option from Florence Santa Maria Novella to Milan Centrale among Omio's users. If you are prioritising price take the bus with prices starting from $10. For those with little time consider booking a train which can get you there in 3h 40m. The ticket price range depends on the travel mode: a bus costs an average of $10, and a flight costs an average of $128.

Distance: 155 miles (250 km)

Compare bus with

Bus
Most popular
Train
Flight
Driving

$22

Average price

Cheapest

$43

Average price

$128

Average price

$90

Average price

(fuel + tolls)

4h 39m

Average total duration

4h 9m

Onboard

+

30m

Additional time*

4h 10m

Average total duration

Fastest

3h 40m

Onboard

+

30m

Additional time*

9h 38m

Average total duration

6h 38m

Onboard

+

3h 0m

Additional time*

3h 20m

Average total duration

(door-to-door)

Direct Options

Direct Options

Direct Options

Direct Options

The cheapest way to travel from Florence Santa Maria Novella to Milan Centrale is a bus with an average price of $22 (€18).

This is compared to other travel options from Florence Santa Maria Novella to Milan Centrale:

A bus is $21 (€17) less than a train for this route with tickets for a train from Florence Santa Maria Novella to Milan Centrale costing on average $43 (€35).

A bus is $106 (€87) less than a flight for this route with tickets for a flight from Florence Santa Maria Novella to Milan Centrale costing on average $128 (€104).

The fastest way to travel from Florence Santa Maria Novella to Milan Centrale is by train with an average journey time of 3h 40m.

Other travel options to Milan Centrale take longer:

Bus takes on average 4h 9m.

Flight takes on average 6h 38m.

It's helpful to compare your options as there are 3 ways to travel between Florence Santa Maria Novella and Milan Centrale including taking a bus, train, and flight.
We recommend using the train as it is the most popular way to get from Florence Santa Maria Novella to Milan Centrale among Omio's users.
Take the bus. It's the cheapest way to make this trip, and the price gap is usually bigger than people expect.

Tickets start at around $22 (€18) compared to roughly $90 (€73) in fuel and tolls — a saving of about $68 (€56). The journey takes 4h 9m versus 3h 20m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.

Direct services are operated by FlixBus, Itabus, BlaBlaCar, BlaBlaCar Bus, Marino Autolinee, Calanda Viaggi.

Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.

Florence Santa Maria Novella to Milan Centrale Bus Timetables

OperatorDeparture TimeArrival TimeDurationDeparture daysCheapest price
Operator
FlixBus
Departure Time
12:05AM
Arrival Time
04:00AM
Duration
3h55
Departure days
Sun
Cheapest price
$18
Operator
BlaBlaCar
Departure Time
12:10AM
Arrival Time
03:20AM
Duration
3h10
Departure days
Fri
Cheapest price
$24
Operator
Itabus
Departure Time
01:05AM
Arrival Time
05:55AM
Duration
4h50
Departure days
Tue
Cheapest price
$17
Operator
FlixBus
Departure Time
01:50AM
Arrival Time
05:15AM
Duration
3h25
Departure days
Sun
Cheapest price
$18
Operator
Marino Autolinee
Departure Time
02:15AM
Arrival Time
07:00AM
Duration
4h45
Departure days
Sun
Cheapest price
$59
Operator
FlixBus
Departure Time
02:15AM
Arrival Time
06:55AM
Duration
4h40
Departure days
Sun
Cheapest price
$18
Operator
FlixBus
Departure Time
02:40AM
Arrival Time
06:55AM
Duration
4h15
Departure days
Sun
Cheapest price
$18
Operator
FlixBus
Departure Time
04:15AM
Arrival Time
08:35AM
Duration
4h20
Departure days
Sun
Cheapest price
$18
Operator
FlixBus
Departure Time
04:35AM
Arrival Time
07:50AM
Duration
3h15
Departure days
Sun
Cheapest price
$18
Operator
FlixBus
Departure Time
05:15AM
Arrival Time
10:00AM
Duration
4h45
Departure days
Tue
Cheapest price
$14
Operator
Trenitalia
Departure Time
06:03AM
Arrival Time
03:17PM
Duration
9h14
Departure days
Fri
Cheapest price
$32
Operator
BlaBlaCar
Departure Time
06:30AM
Arrival Time
09:40AM
Duration
3h10
Departure days
Sat
Cheapest price
$24
Operator
FlixBus
Departure Time
06:35AM
Arrival Time
11:10AM
Duration
4h35
Departure days
Sun
Cheapest price
$29
Operator
Trenitalia
Departure Time
07:09AM
Arrival Time
03:17PM
Duration
8h08
Departure days
Fri
Cheapest price
$32
Operator
FlixBus
Departure Time
07:15AM
Arrival Time
12:25PM
Duration
5h10
Departure days
Sun
Cheapest price
$18
Operator
Italo
Departure Time
07:25AM
Arrival Time
03:17PM
Duration
7h52
Departure days
Mon, Fri, Sat
Cheapest price
$42
Operator
Italo
Departure Time
07:39AM
Arrival Time
03:17PM
Duration
7h38
Departure days
Mon, Fri, Sat
Cheapest price
$42
Operator
FlixBus
Departure Time
07:40AM
Arrival Time
11:55AM
Duration
4h15
Departure days
Sun
Cheapest price
$26
Operator
Italo
Departure Time
08:25AM
Arrival Time
03:17PM
Duration
6h52
Departure days
Mon, Fri, Sat
Cheapest price
$42
Operator
Italo
Departure Time
08:39AM
Arrival Time
03:17PM
Duration
6h38
Departure days
Mon, Fri, Sat
Cheapest price
$42
Operator
FlixBus
Departure Time
08:55AM
Arrival Time
01:45PM
Duration
4h50
Departure days
Sun
Cheapest price
$18
Operator
Italo
Departure Time
09:05AM
Arrival Time
04:40PM
Duration
7h35
Departure days
Mon, Thu, Fri
Cheapest price
$42
Operator
Regionale
Departure Time
09:09AM
Arrival Time
02:15PM
Duration
5h06
Departure days
Mon, Thu, Fri
Cheapest price
$51
Operator
Itabus
Departure Time
09:20AM
Arrival Time
01:45PM
Duration
4h25
Departure days
Wed
Cheapest price
$13
Operator
FlixBus
Departure Time
09:20AM
Arrival Time
12:45PM
Duration
3h25
Departure days
Sun
Cheapest price
$23
Operator
Italo
Departure Time
09:25AM
Arrival Time
04:40PM
Duration
7h15
Departure days
Mon, Thu, Fri
Cheapest price
$44
Operator
Italo
Departure Time
09:39AM
Arrival Time
04:40PM
Duration
7h01
Departure days
Mon, Thu, Fri
Cheapest price
$44
Operator
BlaBlaCar
Departure Time
09:40AM
Arrival Time
01:00PM
Duration
3h20
Departure days
Sat
Cheapest price
$31
Operator
Italo
Departure Time
10:05AM
Arrival Time
04:40PM
Duration
6h35
Departure days
Mon, Thu, Fri
Cheapest price
$42
Operator
FlixBus
Departure Time
10:20AM
Arrival Time
03:20PM
Duration
5h00
Departure days
Sun
Cheapest price
$38
Operator
Regionale
Departure Time
10:20AM
Arrival Time
02:15PM
Duration
3h55
Departure days
Mon, Thu, Fri
Cheapest price
$51
Operator
Itabus
Departure Time
10:20AM
Arrival Time
03:10PM
Duration
4h50
Departure days
Wed
Cheapest price
$16
Operator
FlixBus
Departure Time
11:25AM
Arrival Time
04:25PM
Duration
5h00
Departure days
Sun
Cheapest price
$18
Operator
FlixBus
Departure Time
11:35AM
Arrival Time
04:35PM
Duration
5h00
Departure days
Tue
Cheapest price
$20
Operator
Regionale
Departure Time
11:38AM
Arrival Time
04:15PM
Duration
4h37
Departure days
Mon, Thu, Fri
Cheapest price
$51
Operator
FlixBus
Departure Time
11:55AM
Arrival Time
05:10PM
Duration
5h15
Departure days
Sun
Cheapest price
$18
Operator
FlixBus
Departure Time
12:20PM
Arrival Time
04:30PM
Duration
4h10
Departure days
Tue
Cheapest price
$19
Operator
Regionale
Departure Time
12:37PM
Arrival Time
06:15PM
Duration
5h38
Departure days
Mon, Thu, Fri
Cheapest price
$51
Operator
BlaBlaCar
Departure Time
01:00PM
Arrival Time
05:00PM
Duration
4h00
Departure days
Thu
Cheapest price
$26
Operator
FlixBus
Departure Time
01:20PM
Arrival Time
05:30PM
Duration
4h10
Departure days
Tue
Cheapest price
$15
Operator
BlaBlaCar
Departure Time
01:20PM
Arrival Time
04:20PM
Duration
3h00
Departure days
Mon
Cheapest price
$29
Operator
FlixBus
Departure Time
01:35PM
Arrival Time
06:35PM
Duration
5h00
Departure days
Sun
Cheapest price
$18
Operator
FlixBus
Departure Time
01:50PM
Arrival Time
07:20PM
Duration
5h30
Departure days
Sun
Cheapest price
$18
Operator
BlaBlaCar
Departure Time
02:00PM
Arrival Time
06:00PM
Duration
4h00
Departure days
Fri
Cheapest price
$23
Operator
BlaBlaCar Bus
Departure Time
02:15PM
Arrival Time
06:40PM
Duration
4h25
Departure days
Sun
Cheapest price
$15
Operator
FlixBus
Departure Time
02:20PM
Arrival Time
06:30PM
Duration
4h10
Departure days
Sun
Cheapest price
$36
Operator
FlixBus
Departure Time
03:25PM
Arrival Time
08:00PM
Duration
4h35
Departure days
Sun
Cheapest price
$47
Operator
FlixBus
Departure Time
04:10PM
Arrival Time
08:55PM
Duration
4h45
Departure days
Tue, Sun
Cheapest price
$12
Operator
BlaBlaCar
Departure Time
04:30PM
Arrival Time
07:50PM
Duration
3h20
Departure days
Fri
Cheapest price
$26
Operator
FlixBus
Departure Time
04:30PM
Arrival Time
07:55PM
Duration
3h25
Departure days
Wed
Cheapest price
$20
Operator
FlixBus
Departure Time
04:45PM
Arrival Time
09:35PM
Duration
4h50
Departure days
Wed
Cheapest price
$19
Operator
BlaBlaCar
Departure Time
04:50PM
Arrival Time
08:30PM
Duration
3h40
Departure days
Thu
Cheapest price
$28
Operator
BlaBlaCar
Departure Time
05:00PM
Arrival Time
08:00PM
Duration
3h00
Departure days
Mon, Thu
Cheapest price
$24
Operator
FlixBus
Departure Time
05:05PM
Arrival Time
08:55PM
Duration
3h50
Departure days
Sun
Cheapest price
$36
Operator
BlaBlaCar
Departure Time
05:10PM
Arrival Time
08:00PM
Duration
2h50
Departure days
Fri, Sat
Cheapest price
$24
Operator
BlaBlaCar
Departure Time
05:20PM
Arrival Time
09:20PM
Duration
4h00
Departure days
Fri
Cheapest price
$18
Operator
BlaBlaCar
Departure Time
05:30PM
Arrival Time
08:50PM
Duration
3h20
Departure days
Sat
Cheapest price
$31
Operator
FlixBus
Departure Time
05:30PM
Arrival Time
08:55PM
Duration
3h25
Departure days
Wed
Cheapest price
$24
Operator
BlaBlaCar
Departure Time
05:37PM
Arrival Time
09:17PM
Duration
3h40
Departure days
Sat
Cheapest price
$31
Operator
FlixBus
Departure Time
05:45PM
Arrival Time
10:35PM
Duration
4h50
Departure days
Wed
Cheapest price
$13
Operator
FlixBus
Departure Time
06:00PM
Arrival Time
11:05PM
Duration
5h05
Departure days
Tue, Wed
Cheapest price
$23
Operator
BlaBlaCar
Departure Time
06:00PM
Arrival Time
09:30PM
Duration
3h30
Departure days
Mon
Cheapest price
$24
Operator
FlixBus
Departure Time
06:10PM
Arrival Time
10:20PM
Duration
4h10
Departure days
Sun
Cheapest price
$20
Operator
FlixBus
Departure Time
06:45PM
Arrival Time
11:35PM
Duration
4h50
Departure days
Sun
Cheapest price
$18
Operator
FlixBus
Departure Time
07:00PM
Arrival Time
12:05AM
Duration
5h05
Departure days
Tue, Wed
Cheapest price
$14
Operator
BlaBlaCar
Departure Time
07:30PM
Arrival Time
10:20PM
Duration
2h50
Departure days
Mon
Cheapest price
$33
Operator
FlixBus
Departure Time
07:30PM
Arrival Time
03:00AM
Duration
7h30
Departure days
Tue
Cheapest price
$54
Operator
FlixBus
Departure Time
07:45PM
Arrival Time
11:00PM
Duration
3h15
Departure days
Sun
Cheapest price
$36
Operator
BlaBlaCar
Departure Time
08:00PM
Arrival Time
10:50PM
Duration
2h50
Departure days
Mon, Thu
Cheapest price
$28
Operator
FlixBus
Departure Time
08:00PM
Arrival Time
01:05AM
Duration
5h05
Departure days
Sun
Cheapest price
$21
Operator
FlixBus
Departure Time
09:00PM
Arrival Time
03:00AM
Duration
6h00
Departure days
Wed
Cheapest price
$31
Operator
BlaBlaCar
Departure Time
09:10PM
Arrival Time
12:10AM
Duration
3h00
Departure days
Thu
Cheapest price
$28
Operator
FlixBus
Departure Time
09:40PM
Arrival Time
02:00AM
Duration
4h20
Departure days
Tue, Wed
Cheapest price
$29
Operator
FlixBus
Departure Time
10:05PM
Arrival Time
06:55AM
Duration
8h50
Departure days
Tue
Cheapest price
$29
Operator
FlixBus
Departure Time
10:40PM
Arrival Time
03:00AM
Duration
4h20
Departure days
Tue
Cheapest price
$22
Operator
FlixBus
Departure Time
11:40PM
Arrival Time
04:00AM
Duration
4h20
Departure days
Sun
Cheapest price
$43

Live departures

Florence Santa Maria Novella to Milan Centrale bus times

The table below shows live departures for Florence Santa Maria Novella to Milan Centrale buses for today, Thursday, June 18. You can also manually refresh the results below to see updated bus journeys.

Last updated at
ProviderDepartsDurationArrivesTransfers
Tickets
Italo8954+TrenitaliaBUS LP6049:05 AM Florence Santa Maria Novella
7h35
4:40 PM Milan Centrale1 transfer
RegionaleRegionale 18508 · Treno 17820 effettuato con bus FI680+Italo99769:09 AM Florence Santa Maria Novella
4h06
1:15 PM Milan Centrale2 transfers
RegionaleRegionale 18508 · Treno 17820 effettuato con bus FI680+Italo99789:09 AM Florence Santa Maria Novella
5h06
2:15 PM Milan Centrale2 transfers
Italo9912+TrenitaliaBUS LP6049:25 AM Florence Santa Maria Novella
7h15
4:40 PM Milan Centrale1 transfer
Italo8904+TrenitaliaBUS LP6049:39 AM Florence Santa Maria Novella
7h01
4:40 PM Milan Centrale1 transfer
Italo8956+TrenitaliaBUS LP60410:05 AM Florence Santa Maria Novella
6h35
4:40 PM Milan Centrale1 transfer
RegionaleRegionale 18664 · Autobus TTPER B0400+Italo992810:20 AM Florence Santa Maria Novella
5h00
3:20 PM Milan Centrale2 transfers
RegionaleRegionale 18664 · Autobus TTPER B0400+Italo998210:20 AM Florence Santa Maria Novella
5h55
4:15 PM Milan Centrale2 transfers
RegionaleRegionale 18664 · Autobus TTPER B0400+Italo997810:20 AM Florence Santa Maria Novella
3h55
2:15 PM Milan Centrale2 transfers
RegionaleRegionale 18490 · Autobus TTPER B0402+Italo998611:38 AM Florence Santa Maria Novella
6h37
6:15 PM Milan Centrale2 transfers
RegionaleRegionale 18490 · Autobus TTPER B0402+Italo998211:38 AM Florence Santa Maria Novella
4h37
4:15 PM Milan Centrale2 transfers
RegionaleRegionale 18490 · Autobus TTPER B0402+Italo993211:38 AM Florence Santa Maria Novella
4h42
4:20 PM Milan Centrale2 transfers
RegionaleRegionale 18492 · Autobus TTPER B0404+Italo998212:37 PM Florence Santa Maria Novella
3h38
4:15 PM Milan Centrale2 transfers
RegionaleRegionale 18492 · Autobus TTPER B0404+Italo998612:37 PM Florence Santa Maria Novella
5h38
6:15 PM Milan Centrale2 transfers
RegionaleRegionale 18492 · Autobus TTPER B0404+Italo813412:37 PM Florence Santa Maria Novella
4h43
5:20 PM Milan Centrale2 transfers
RegionaleRegionale 18488 · Regionale 17806+TrenitaliaBUS L580A6:03 AM Florence Santa Maria Novella
9h14
3:17 PM Milan Centrale2 transfers
RegionaleRegionale 18502 · Regionale 17808+TrenitaliaBUS L580A7:09 AM Florence Santa Maria Novella
8h08
3:17 PM Milan Centrale2 transfers
Italo9904+TrenitaliaBUS L580A7:25 AM Florence Santa Maria Novella
7h52
3:17 PM Milan Centrale1 transfer
Italo9904+TrenitaliaBUS LP6047:25 AM Florence Santa Maria Novella
9h15
4:40 PM Milan Centrale1 transfer
Italo8900+TrenitaliaBUS LP6047:39 AM Florence Santa Maria Novella
9h01
4:40 PM Milan Centrale1 transfer
Italo8900+TrenitaliaBUS L580A7:39 AM Florence Santa Maria Novella
7h38
3:17 PM Milan Centrale1 transfer
Italo9908+TrenitaliaBUS L580A8:25 AM Florence Santa Maria Novella
6h52
3:17 PM Milan Centrale1 transfer
Italo9908+TrenitaliaBUS LP6048:25 AM Florence Santa Maria Novella
8h15
4:40 PM Milan Centrale1 transfer
Italo8924+TrenitaliaBUS LP6048:39 AM Florence Santa Maria Novella
8h01
4:40 PM Milan Centrale1 transfer
Italo8924+TrenitaliaBUS L580A8:39 AM Florence Santa Maria Novella
6h38
3:17 PM Milan Centrale1 transfer

Find all the dates and times for this journey

Compare prices and tickets Florence Santa Maria Novella to Milan Centrale by bus, train, or flight

Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

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Why should you book Florence Santa Maria Novella to Milan Centrale buses with Omio?

FlixBus as well as Itabus, BlaBlaCar Bus, Marino Autolinee, Calanda Viaggi and more offer buses services from Florence Santa Maria Novella to Milan Centrale.
Omio is an official ticket reseller for all your travel options from Florence Santa Maria Novella to Milan Centrale.

Why book with Omio vs FlixBus?

  • Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of Itabus, BlaBlaCar Bus, Marino Autolinee or Calanda Viaggi to find the best option for your trip from Florence Santa Maria Novella to Milan Centrale.
  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Florence Santa Maria Novella to Milan Centrale.

Why book with Omio over Wanderu, Trainline or Checkmybus?

  • Compare with other providers: On Omio, you can also compare tickets for the likes of Itabus, BlaBlaCar Bus, Marino Autolinee or Calanda Viaggi to find the best option for your trip from Florence Santa Maria Novella to Milan Centrale.
  • Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Florence Santa Maria Novella to Milan Centrale.

Journey information

Overview: Bus from Florence Santa Maria Novella to Milan Centrale

ItalyItaly
ItalyItaly
Icon of bus

Buses from Florence Santa Maria Novella to Milan Centrale run on average 32 times per day, taking around 4h 9m. Cheap bus tickets for this journey start at $10 (€8) if you book in advance.

There are 27 buses per day. The earliest bus runs at 00:05, the last at 23:20. The fastest bus covers the 155 miles (250 km) distance in 3h 15m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
155 miles (250 km)
Average bus duration
4h 9m
Cheapest ticket price
$10 (€8)
Buses per day
32
Direct buses
27
Fastest bus
3h 15m
First bus
12:05 AM
Last bus
11:20 PM
Cheapest Month
Aug
Cheapest Day
Sat
High Season
Apr - Jun
Low Season
Jan - Mar
Busiest Day
Mon
Least Busy Day
Sat
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Bus providers: FlixBus, Itabus, BlaBlaCar, BlaBlaCar Bus, Marino Autolinee, Calanda Viaggi from Florence Santa Maria Novella to Milan CentraleYou can travel by bus between Florence Santa Maria Novella to Milan Centrale with FlixBus, Itabus, BlaBlaCar, BlaBlaCar Bus, Marino Autolinee, Calanda Viaggi for as low as $10 (€8). When you search for schedules and tickets, Omio will show you the best journey

FlixBus

About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
3h 15m
Cheapest Price
$12 (€10)
FlixBus frequency
28 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.

Itabus

About
Itabus is a leading bus company in Italy, providing reliable and comfortable transportation services to its customers. Itabus operates a fleet of modern buses, ranging from luxury coaches to standard buses, all equipped with air conditioning, comfortable seating, and onboard entertainment.
Luggage & cancellation policy
Average Duration
4h 25m
Cheapest Price
$10 (€8)
Itabus frequency
14 a day
Luggage included
One carry-on bag up to 10kg and one checked bag up to 20kg.
Additional luggage
5€ per additional bag.
Cancellation Policy
You can cancel your ticket up to 24 hours before departure for a partial refund. Changes allowed for a fee.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Dedicated seating areas; Accessible restrooms.
Bikes
Bikes are allowed.
Pets
Small pets allowed in carriers; larger pets must be leashed and muzzled.

Marino Autolinee

About
MarinoBus is an Italian bus company with more than 200 destinations and 6,000 connections across Italy and Europe. Originally focused on Basilicata and Apulia, its network has expanded to cover the rest of Italy as well as Switzerland, France, Germany, and Luxembourg. All MarinoBus coaches are equipped with spacious reclining seats, air conditioning, onboard restrooms, WiFi, minibars, and color TVs. For your next trip, you can book the standard ticket, which includes one piece of hand luggage and up to two checked bags per passenger
Luggage & cancellation policy
Marino Autolinee frequency
2 a day
Luggage included
One carry-on bag up to 10kg (55x40x20 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
10€ per additional bag up to 20 kg.
Cancellation Policy
You can cancel your ticket up to 24 hours before departure for a full refund. Cancellations within 24 hours incur a 50% fee.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Accessible restrooms.
Bikes
Bikes are allowed.
Pets
Small pets allowed in carriers; larger pets must be leashed and muzzled.

BlaBlaCar Bus

About
BlaBlaCar Bus (formerly known as Ouibus or iDBUS) is a long-distance coach company operating in 10 European countries and connecting over 300 destinations. A subsidiary of the French carpooling company BlaBlaCar, it offers comfortable travel with standard amenities such as air conditioning, toilets, USB and power outlets for charging devices, extra legroom, and adjustable seats. Free Wi-Fi is available on select routes. BlaBlaCar Bus offers only a Standard ticket type, which allows passengers to bring one carry-on bag and up to two checked bags per person.
Luggage & cancellation policy
Average Duration
4h 25m
Cheapest Price
$11 (€9)
BlaBlaCar Bus frequency
1 a day
Luggage included
One carry-on bag up to 7kg and one checked bag up to 20kg.
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 30 minutes before departure for a refund in the form of a voucher.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Accessible seating options.
Bikes
Bikes are allowed; additional fees may apply.

Calanda Viaggi

About
Calanda Viaggi is an Italian bus company that originated in Switzerland in 1989 as Calanda Reisen, founded to serve Italian communities traveling to and from their home country. Headquartered in Chiaravalle Centrale, Italy, Calanda Viaggi connects a significant portion of Italy, including regions like Calabria, Tuscany, and Lombardy, with various Swiss cities such as Zurich, Bern, and Basel. The company emphasizes affordability and a comfortable onboard experience, offering amenities like air conditioning, restrooms, and often Wi-Fi and movie screenings. Calanda Viaggi also provides bus and minibus rentals for various events and organized trips within Italy and Europe.
Luggage & cancellation policy
Calanda Viaggi frequency
3 a day
Luggage included
One checked bag and one small hand luggage item are generally included, but specific size and weight details are not explicitly stated and may vary.
Additional luggage
Additional luggage may be allowed, but details on fees and restrictions are not specified.
Cancellation Policy
The cancellation policy can vary by ticket class, individual trips, or promotions; passengers should check the policies during the booking process.
Pregnant on board
Calanda Viaggi does not impose restrictions on flying if you are pregnant, but it is advisable to check with your doctor if traveling after the eighth month.
Unaccompagned minor
Unaccompanied minors must have an authorization form signed by their parents.
Amenities on board the bus
Wifi
Toilets
USB plugs

BlaBlaCar

About
BlaBlaCar is a French online marketplace for carpooling, connecting drivers with empty seats and passengers traveling to the same destination to share costs. Founded in 2006, it operates in Europe and Latin America, boasting 26 million active members. The platform also includes BlaBlaCar Bus, an intercity bus service. BlaBlaCar's name comes from its rating system for drivers' chattiness: "Bla" for quiet, "BlaBla" for talkative, and "BlaBlaBla" for very chatty. The company aims to be the leading marketplace for shared travel, offering affordable and sustainable solutions by combining carpooling with bus journeys.
Luggage & cancellation policy
BlaBlaCar frequency
4 a day

Complete guide to Milano Centrale

Things to do in Milano Centrale

Discover the best of Milano Centrale — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Milano Centrale trip today.

  • Must visit

Pinacoteca di Brera

One of Milan’s premier art museums, known for masterpieces by Raphael, Caravaggio, and Mantegna in the historic Brera district.

  • Must visit

Leonardo da Vinci National Museum of Science and Technology

Italy’s largest science museum, featuring Leonardo-inspired displays, transport collections, and interactive exhibits in a former monastery.

  • Recommended

Museo del Novecento

A major museum of 20th-century Italian art facing Piazza del Duomo, especially noted for Futurist works and its central location.

Euro

Prices are above the Italian average, especially near the station. Casual meals are manageable, but hotels and sit-down dining cost more.

Average meal costs

Budget
EUR 8-15 for pizza, panini, or takeaway.
Mid-range
EUR 20-35 per person for a standard restaurant meal.
Fine dining
EUR 70+ per person at upscale restaurants.
Coffee
EUR 1.20-2.50 for espresso or cappuccino.

Tipping culture

Service is often included or covered by a coperto. Tipping is not mandatory; round up or leave EUR 1-5 for good service. Taxis can be rounded up.

FAQs: Bus from Florence Santa Maria Novella to Milan Centrale

Find answers to the most common questions about traveling from Florence Santa Maria Novella to Milan Centrale by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Milan Centrale, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Florence Santa Maria Novella to Milan Centrale can start from as little as $10 (€8) when you book in advance. The average bus ticket price for Florence Santa Maria Novella to Milan Centrale is $22 (€18) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Florence Santa Maria Novella to Milan Centrale is 3h 15m to travel the 155 miles (250 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Florence Santa Maria Novella to Milan Centrale leaves at 12:05 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Florence Santa Maria Novella to Milan Centrale leaves at 11:20 PM.
Yes, there are 27 direct buses a day from Florence Santa Maria Novella to Milan Centrale with FlixBus, Itabus, BlaBlaCar, BlaBlaCar Bus, Marino Autolinee, Calanda Viaggi. Schedules can vary on holidays or weekends with fewer direct buses.
When taking a bus from Florence Santa Maria Novella to Milan Centrale, you can count on FlixBus, Itabus, BlaBlaCar, BlaBlaCar Bus, Marino Autolinee, Calanda Viaggi for the best way to get you to Milan Centrale. You can also check all possible bus companies who offer a service between Florence Santa Maria Novella and Milan Centrale and compare the amenities they offer before buying a bus ticket.
A trip to Milan Centrale from Florence Santa Maria Novella is worth doing but not as a day trip with a journey time of 3h 15m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Florence Santa Maria Novella to Milan Centrale is August.
It's helpful to compare your options as there are 3 ways to travel between Florence Santa Maria Novella and Milan Centrale including taking a bus, train, and flight.
Yes, the following accessibility options are available when taking the bus from Florence Santa Maria Novella to Milan Centrale:
  • BlaBlaCar Bus
    • Assistance
    • Priority boarding
    • Accessible seating options.
  • FlixBus
    • Assistance
    • Priority boarding
    • Wheelchair-accessible buses.
  • Itabus
    • Assistance
    • Dedicated seating areas
    • Accessible restrooms.
Yes, there are bathrooms on board the bus from Florence Santa Maria Novella to Milan Centrale for bus company FlixBus, Itabus, BlaBlaCar Bus, Marino Autolinee, Calanda Viaggi.
Whether you can cancel your bus ticket from Florence Santa Maria Novella to Milan Centrale depends on the bus companies:
  • BlaBlaCar Bus
    • You can cancel your ticket up to 30 minutes before departure for a refund in the form of a voucher.
  • FlixBus
    • You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
  • Itabus
    • You can cancel your ticket up to 24 hours before departure for a partial refund. Changes allowed for a fee.
Yes, bikes are allowed on board the bus with bus company FlixBus, Itabus, BlaBlaCar Bus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Florence Santa Maria Novella to Milan Centrale.
Yes, the following luggage options are included when booking a bus ticket from Florence Santa Maria Novella to Milan Centrale:
  • BlaBlaCar Bus
    • One carry-on bag up to 7kg and one checked bag up to 20kg.
  • FlixBus
    • One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
  • Itabus
    • One carry-on bag up to 10kg and one checked bag up to 20kg.
Yes, the following additional luggage options are available when booking a bus ticket from Florence Santa Maria Novella to Milan Centrale:
  • BlaBlaCar Bus
    • Additional luggage can be purchased for a fee.
  • FlixBus
    • Additional luggage can be purchased for a fee.
  • Itabus
    • 5€ per additional bag.
Yes, you can bring your pet on the bus from Florence Santa Maria Novella to Milan Centrale. The following conditions apply:
  • Marino Autolinee
    • Small pets allowed in carriers
    • larger pets must be leashed and muzzled.
  • FlixBus
    • Small pets in carriers allowed
    • guide dogs travel for free.
  • Itabus
    • Small pets allowed in carriers
    • larger pets must be leashed and muzzled.
You can reserve your seat on the bus from Florence Santa Maria Novella to Milan Centrale with the following bus company: FlixBus, Itabus, BlaBlaCar Bus, Marino Autolinee
Yes, there are USB plugs on board the bus from Florence Santa Maria Novella to Milan Centrale with the following bus company: FlixBus, Itabus, BlaBlaCar Bus, Marino Autolinee, Calanda Viaggi.
Yes, there is Wifi on board the bus from Florence Santa Maria Novella to Milan Centrale with the following bus company: FlixBus, Itabus, BlaBlaCar Bus, Marino Autolinee, Calanda Viaggi.
Since both Florence Santa Maria Novella and Milan Centrale are in the Schengen Area, a passport is not required for European Union (EU) or Schengen-associated country citizens. A national ID card is sufficient.
We recommend using the train as it is the most popular way to get from Florence Santa Maria Novella to Milan Centrale among Omio's users.
Italy uses the euro (EUR) as its currency. Travelers generally find it convenient to use cards for most payments, especially in cities and larger establishments, but carrying some cash is advisable for small shops, markets, and rural areas where card acceptance may be limited.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

More options for your journey from Florence Santa Maria Novella to Milan Centrale

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