- Must visit
Art Institute of Chicago
World-class art museum with masterpieces from Monet to Hopper and the famous Modern Wing.
Omio recommends booking the bus as it is the most popular option from Meridian, MS to Chicago, IL among Omio's users. If you are prioritising price take the bus with prices starting from $292. For those with little time consider booking a bus which can get you there in 18h 16m. The ticket price range depends on the travel mode: a bus costs an average of $292, and a bus costs an average of $292.
Distance: 658 miles (1059 km)
Most popular Bus | Driving |
|---|---|
$292 Average price Cheapest | $31 Average price (fuel + tolls) |
18h 46m Average total duration Fastest 18h 16m Onboard + 30m Additional time* | 11h 34m Average total duration (door-to-door) |
![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options |
Other travel options to Chicago, IL take longer:
Train takes on average 40h 50m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Flixbus USA | Departure Time 02:45AM | Arrival Time 10:05PM | Duration 19h20 | Departure days Mon, Tue, Fri, Sat | Cheapest price $147 |
Operator Greyhound | Departure Time 10:50AM | Arrival Time 08:00AM | Duration 21h10 | Departure days Wed, Sun | Cheapest price $109 |
Operator Greyhound | Departure Time 03:40PM | Arrival Time 02:10PM | Duration 22h30 | Departure days Wed, Sun | Cheapest price $131 |
Operator Greyhound | Departure Time 07:10PM | Arrival Time 08:10PM | Duration 25h00 | Departure days Wed, Sun | Cheapest price $110 |
The table below shows live departures for Meridian, MS to Chicago, IL buses for today, Wednesday, August 5. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
· · | 10:50 AM Meridian, Front St (Union Station), MS | 17h30 | 4:20 AM Chicago, Greyhound Bus Station | 2 transfers | |
· · · | 10:50 AM Meridian, Front St (Union Station), MS | 21h10 | 8:00 AM Chicago, Union Station (Amtrak), IL | 3 transfers | |
· · | 3:40 PM Meridian, Front St (Union Station), MS | 22h30 | 2:10 PM Chicago, Greyhound Bus Station | 2 transfers | |
· · | 3:40 PM Meridian, Front St (Union Station), MS | 22h05 | 1:45 PM Chicago, Union Station (Amtrak), IL | 2 transfers | |
· | 7:10 PM Meridian, Front St (Union Station), MS | 25h00 | 8:10 PM Chicago, Greyhound Bus Station | 1 transfer |
Find all the dates and times for this journey
Compare bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Meridian, MS to Chicago, IL run on average 4 times per day, taking around 18h 16m. Cheap bus tickets for this journey start at $292 if you book in advance.
The earliest bus runs at 02:45, the last at 23:10. The fastest bus covers the 658 miles (1059 km) distance in 23h 35m.
Distance 658 miles (1059 km) |
Average bus duration 18h 16m |
Cheapest ticket price $292 |
Buses per day 4 |
Fastest bus 23h 35m |
First bus 2:45 AM |
Last bus 11:10 PM |
Cheapest Month Aug |
Cheapest Day Sun |
High Season Jan - Mar |
Low Season Jul - Sep |
Best time to book 2 days |
Discover the best of Chicago, IL — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Chicago, IL trip today.
World-class art museum with masterpieces from Monet to Hopper and the famous Modern Wing.
Major natural history museum with Sue the T. rex, ancient cultures, and strong family appeal.
Hands-on science museum in a grand former fair building, popular for exhibits and a U-505 submarine.
Lively lakefront park with Cloud Gate, Crown Fountain, gardens, and major public art in central Chicago.
Famous shopping boulevard lined with architecture, hotels, riverfront views, and major city energy.
Scenic pedestrian-friendly riverwalk with boat docks, public art, bridges, and standout skyline perspectives.
Deep-dish pizza is Chicago’s iconic pie with a tall buttery crust, layers of cheese and toppings, and chunky tomato sauce baked on top.
The Chicago-style hot dog is an all-beef frank on a poppy seed bun with mustard, relish, onion, tomato, pickle, peppers, and celery salt.
Italian beef is thin-sliced roast beef piled onto a roll, often dipped in savory juices and topped with sweet peppers or spicy giardiniera.
Classic spot for juicy Italian beef sandwiches, especially dipped and topped with spicy giardiniera, with a casual local feel.
Legendary stand for Chicago-style hot dogs and char-grilled sausages, served fast in a no-frills local landmark.
World-famous fine dining destination offering a highly creative tasting menu and refined service in an elegant setting.
Moderate for a major US city: hotels can be pricey, but transit is affordable and dining ranges from cheap eats to upscale options.
Tip 18-20% at restaurants, $1-2 per drink at bars, 10-15% for taxis, and optional small change at cafes.
Find answers to the most common questions about traveling from Meridian, MS to Chicago, IL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Chicago, IL, this guide helps you travel smarter and with confidence.

Most Meridian, MS to Chicago, IL buses use the Meridian, Front St (Union Station) to Chicago, Greyhound Bus Station station pair, with some services arriving at Chicago, Union Station (Amtrak). Use this guide to compare Meridian, MS and Chicago, IL bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Meridian, Front St (Union Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Meridian, Front St (Union Station). ATMs are available at Meridian, Front St (Union Station).
Ticket office support is available at Meridian, Front St (Union Station).
Available at Meridian, Front St (Union Station): Parking, Taxis, WC.
Accessibility facilities are available at Meridian, Front St (Union Station): Wheelchair accessible.
Chicago, Greyhound Bus Station is 2 km from Chicago city centre. Public transport options include:
Chicago, Greyhound Bus Station has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Snack shop and vending machines available
Free Wi-Fi in waiting area. ATMs are located near entrance.
Ticket office support is available at Chicago, Greyhound Bus Station.
Available at Chicago, Greyhound Bus Station: Parking, Taxis, WC.
Accessibility facilities are available at Chicago, Greyhound Bus Station: Wheelchair accessible entrances and seating.
Chicago, Union Station (Amtrak) is 3 km from Chicago city centre. Public transport options include:
Chicago, Union Station (Amtrak) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Multiple dining options are available inside the station.
Free Wi-Fi is available in waiting areas. ATMs are aTMs are located near the main entrance.
Ticket office support is available at Chicago, Union Station (Amtrak).
Available at Chicago, Union Station (Amtrak): Parking, Taxis, WC.
Accessibility facilities are available at Chicago, Union Station (Amtrak): Station is accessible with elevators and ramps.
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