- Must visit
Everson Museum of Art
Major regional museum covering art, science, and history. Best known for broad collections, family appeal, and exhibits on Central New York.
The best way to find a cheap bus ticket from Manchester, NH to Syracuse, NY is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Manchester, NH to Syracuse, NY will cost around $110 if you buy it on the day, but the cheapest tickets can be found for only $110.
On Tue, Nov 03, we found 1 buses from Manchester, NH to Syracuse, NY, including 1 direct services.
On Tue, Nov 03 the direct buses cover the 381 km distance in an average of 13 h 25 m but if you time it right, some buses will get you there in just 13 h 25 m .
On Tue, Nov 03 the slowest buses will take 13 h 25 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

|
| ||||||||||||

|
| ||||||||||||
Buses from Manchester, NH to Syracuse, NY run on average 3 times per day, taking around 10h 28m. Cheap bus tickets for this journey start at $59 (€49) if you book in advance.
The earliest bus runs at 00:20, the last at 21:00. The fastest bus covers the 236 miles (381 km) distance in 7h 55m.
Plan this route
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Manchester, NH to Syracuse, NY.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 10:05AM | Arrival Time 11:30PM | Duration 13h25 | Departure days Tue | Cheapest price $110 |
Operator Greyhound USA | Departure Time 07:15PM | Arrival Time 01:40PM | Duration 18h25 | Departure days Mon, Wed, Thu, Fri | Cheapest price $99 |
Operator FlixBus | Departure Time 07:20PM | Arrival Time 09:05AM | Duration 13h45 | Departure days Sun | Cheapest price $91 |
Operator FlixBus | Departure Time 07:35PM | Arrival Time 09:05AM | Duration 13h30 | Departure days Sat | Cheapest price $88 |
The table below shows live departures for Manchester, NH to Syracuse, NY buses for today, Monday, November 2. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 7:15 PM Manchester, NH | 18h25 | 1:40 PM Syracuse, NY | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Buses from Manchester, NH to Syracuse, NY with Greyhound and FlixBus. Overnight buses available on this route with Greyhound and FlixBus. Use the details below to compare onboard facilities.
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
Discover the best of Syracuse, NY — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Syracuse, NY trip today.
Major regional museum covering art, science, and history. Best known for broad collections, family appeal, and exhibits on Central New York.
Historic house museum preserving nineteenth-century Syracuse domestic life. Worth visiting for period rooms and insight into early city society.
Interactive museum focused on science and technology, famous for hands-on exhibits and domed IMAX theater. Great for families and curious visitors.
Historic downtown square and year-round gathering place, known for festivals, fountains, and winter skating. A central stop for city atmosphere.
Scenic waterfront park with long trails, lake views, and birdlife. Popular for walking, cycling, and relaxing near Syracuse's restored shoreline.
Compact downtown district filled with galleries, murals, and restored warehouse buildings. Best explored on foot for arts culture and architecture.
Salt potatoes are small potatoes boiled in heavily salted water, creating a crusty skin and creamy center. They are a Central New York summer staple, often served with butter.
Chicken riggies is a spicy Utica pasta dish popular across Central New York, made with chicken, rigatoni, peppers, and a creamy tomato sauce.
Utica greens are escarole sautéed with hot peppers, garlic, breadcrumbs, and often prosciutto. This Italian American side is beloved throughout the Syracuse area.
Long running market cafe and bakery known for tomato pie, sandwiches, pastries, and a classic Syracuse neighborhood feel.
Established Italian restaurant known for homemade pasta, regional Italian American dishes, and a polished but welcoming atmosphere.
Upscale downtown dining with seasonal American cuisine, thoughtful plating, and a refined setting popular for special occasions.
Moderate for a U.S. city. Hotels are often cheaper than NYC, dining is mid-priced, and most visitors need a car or rideshares as transit is limited.
Tip 18-20% at restaurants, $1-2 per drink at bars, and 10-15% for taxis. Cafes often have tip jars or screen prompts for small tips.
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Syracuse, NY.
Find answers to the most common questions about traveling from Manchester, NH to Syracuse, NY by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Syracuse, NY, this guide helps you travel smarter and with confidence.

Most Manchester, NH to Syracuse, NY buses use the Manchester, Boston Manchester Airport to Syracuse, Walsh Cir (Syracuse Bus Station) station pair. Use this guide to compare Manchester, NH and Syracuse, NY bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Manchester, Boston Manchester Airport is 7 km from Manchester city centre. Public transport options include:
Manchester, Boston Manchester Airport has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: There are dining options available in the terminal.
Free WiFi is available within the airport terminals. ATMs are aTMs are located in the terminal for cash withdrawals.
Ticket office support is available at Manchester, Boston Manchester Airport.
Available at Manchester, Boston Manchester Airport: Parking, Taxis, WC.
Accessibility facilities are available at Manchester, Boston Manchester Airport: The airport is fully accessible with facilities for disabled passengers.
Manchester, Elm St (Veterans Memorial Park) is 1 km from Manchester city centre. Public transport options include:
Manchester, Elm St (Veterans Memorial Park) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Several nearby options
Wi-Fi is available at Manchester, Elm St (Veterans Memorial Park). ATMs are available at Manchester, Elm St (Veterans Memorial Park).
Ticket office support is available at Manchester, Elm St (Veterans Memorial Park).
Available at Manchester, Elm St (Veterans Memorial Park): Parking, Taxis, WC.
Accessibility facilities are available at Manchester, Elm St (Veterans Memorial Park): Wheelchair accessible.
Syracuse, Walsh Cir (Syracuse Bus Station) is 3 km from Syracuse city centre. Public transport options include:
Syracuse, Walsh Cir (Syracuse Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Free Wi-Fi available throughout the station. ATMs are aTMs are located near the entrance.
Ticket office support is available at Syracuse, Walsh Cir (Syracuse Bus Station).
Available at Syracuse, Walsh Cir (Syracuse Bus Station): Parking, Taxis, WC.
Accessibility facilities are available at Syracuse, Walsh Cir (Syracuse Bus Station): The station is wheelchair accessible.
Check bus stations information for Manchester, NH and Syracuse, NY, including where buses depart and arrive on this route.