The cheapest and fastest buses from Louisville, KY to Chicago, IL
Cheapest price
$54
Average price
$60
Fastest journey
5 h 40 m
Average duration
6 h 41 m
Buses per day
4
Distance
431 km
The best way to find a cheap bus ticket from Louisville, KY to Chicago, IL is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Louisville, KY to Chicago, IL will cost around $60 if you buy it on the day, but the cheapest tickets can be found for only $54.
Of the 4 buses that leave Louisville, KY for Chicago, IL on Wed, Nov 19, 4 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Wed, Nov 19 the direct buses cover the 431 km distance in an average of 6 h 41 m but if you time it right, some buses will get you there in just 5 h 40 m .
On Wed, Nov 19 the slowest buses will take 7 h 35 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.








Travel Information
Compare bus and flight for Louisville, KY to Chicago, IL
Omio recommends booking the bus as it is the most popular option from Louisville, KY to Chicago, IL among Omio's users. If you are prioritising price take the bus with prices starting from €34. For those with little time consider booking a flight which can get you there in 1h 39m. The ticket price range depends on the travel mode: a bus costs an average of €34, and a flight costs an average of €43.
Distance: 267 miles (431 km)
Compare bus with
Most popular Bus | Flight |
|---|---|
€52 Average price Cheapest | €324 Average price |
6h 57m Average total duration 6h 27m Onboard + 30m Additional time* | 4h 39m Average total duration Fastest 1h 39m Onboard + 3h 0m Additional time* |
![]() Most popular bus company | ![]() Most popular airline |
Direct Options | Direct Options |
Live departures
Louisville, KY to Chicago, IL bus times
The table below shows live departures for Louisville, KY to Chicago, IL buses for today, Tuesday, November 18. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 12:00 PM Louisville, KY | 7h35 | 7:35 PM Chicago, IL | 0 transfersDirect | |
![]() | 6:35 PM Louisville, KY | 6h35 | 1:10 AM Chicago, IL | 0 transfersDirect | |
![]() | 11:30 PM Louisville, KY | 5h40 | 5:10 AM Chicago, IL | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Louisville, KY to Chicago, IL by bus or flight
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Nov 19
Nov 20
Nov 21
Nov 22
Nov 23
Nov 24
Nov 25
Journey information
Overview: Bus from Louisville, KY to Chicago, IL
Buses from Louisville, KY to Chicago, IL run on average 8 times per day, taking around 6h 27m. Cheap bus tickets for this journey start at $42 (€34) if you book in advance.
There are 8 buses per day. The earliest bus runs at 01:50, the last at 22:30. The fastest bus covers the 267 miles (431 km) distance in 5h 40m.
Distance 267 miles (431 km) |
Average bus duration 6h 27m |
Cheapest ticket price $42 (€34) |
Buses per day 8 |
Direct buses 8 |
Fastest bus 5h 40m |
First bus 01:50 |
Last bus 22:30 |
Bus providers: Greyhound, FlixBus, Transit Authority of River City from Louisville, KY to Chicago, ILYou can travel by bus between Louisville, KY to Chicago, IL with Greyhound, FlixBus, Transit Authority of River City for as low as $42 (€34). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Greyhound
Transit Authority of River City
FAQs: Bus from Louisville, KY to Chicago, IL
Find answers to the most common questions about traveling from Louisville, KY to Chicago, IL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Chicago, IL, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Millennium Park, a public park known for its modern art installations and the iconic Cloud Gate sculpture
- Art Institute of Chicago, a renowned museum housing an extensive collection of art from around the world
- Navy Pier, a popular entertainment destination featuring rides, restaurants, and lakefront views
- Willis Tower Skydeck, an observation deck offering panoramic views of the city from one of the tallest buildings in the Western Hemisphere
- Field Museum, a natural history museum with vast exhibits including the famous T. Rex skeleton, Sue.
- Museum of Science and Industry, an interactive museum featuring exhibits on science, technology, and industry
- Explore the vibrant neighborhoods of Chicago, such as Wicker Park and Lincoln Park, known for their unique shops and eateries
- Take a river cruise to see the city's iconic architecture from a different perspective
- Attend a live performance at the historic Chicago Theatre
- Enjoy a day at Lincoln Park Zoo, one of the oldest zoos in the U. S. Offering free admission.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
To find the cheapest bus tickets for your trip from Louisville, KY to Chicago, IL, follow these tips:
Start your search now and compare ticket prices to find the best deal!
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Greyhound
- $15 per additional bag.
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- Guide dogs travel for free.
popular bus stations
Popular bus stations from Louisville, KY to Chicago, IL
Most popular bus connections from Louisville, KY
More options for your journey from Louisville, KY to Chicago, IL
Here are some other resources that might have the information you need

