Louisville, KY to Chicago, IL bus with Greyhound

Wed, Nov 19
+ Add return
Greyhound
FlixBus
Transit Authority of River City
Alsa
BlaBlaCar Bus
1,000+ travel companies
Greyhound
FlixBus
Transit Authority of River City
Alsa
BlaBlaCar Bus
1,000+ travel companies
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The cheapest and fastest buses from Louisville, KY to Chicago, IL

Showing times and prices for Nov 19

Cheapest price

$54

Average price

$60

Fastest journey

5 h 40 m

Average duration

6 h 41 m

Buses per day

4

Distance

431 km

Cheap tickets

The best way to find a cheap bus ticket from Louisville, KY to Chicago, IL is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Louisville, KY to Chicago, IL will cost around $60 if you buy it on the day, but the cheapest tickets can be found for only $54.

Fast buses

Of the 4 buses that leave Louisville, KY for Chicago, IL on Wed, Nov 19, 4 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.

On Wed, Nov 19 the direct buses cover the 431 km distance in an average of 6 h 41 m but if you time it right, some buses will get you there in just 5 h 40 m .

On Wed, Nov 19 the slowest buses will take 7 h 35 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

Greyhound
12:00PM7h35
Louisville, KY
07:35PMChicago, IL
$541One-way
0 transfers
Greyhound
06:35PM6h35
Louisville, KY
01:10AMChicago, IL
$551One-way
0 transfers
FlixBus
08:05PM6h55
Louisville, KY
03:00AMChicago, IL
$631One-way
0 transfers
FlixBus
11:30PM5h40
Louisville, KY
05:10AMChicago, IL
$671One-way
0 transfers

Travel Information

Compare bus and flight for Louisville, KY to Chicago, IL

Omio recommends booking the bus as it is the most popular option from Louisville, KY to Chicago, IL among Omio's users. If you are prioritising price take the bus with prices starting from €34. For those with little time consider booking a flight which can get you there in 1h 39m. The ticket price range depends on the travel mode: a bus costs an average of €34, and a flight costs an average of €43.

Distance: 267 miles (431 km)

Compare bus with

Most popular
Bus
Flight

€52

Average price

Cheapest

€324

Average price

6h 57m

Average total duration

6h 27m

Onboard

+

30m

Additional time*

4h 39m

Average total duration

Fastest

1h 39m

Onboard

+

3h 0m

Additional time*

Greyhound

Most popular bus company

Republic Airlines

Most popular airline

Direct Options

Direct Options

Live departures

Louisville, KY to Chicago, IL bus times

The table below shows live departures for Louisville, KY to Chicago, IL buses for today, Tuesday, November 18. You can also manually refresh the results below to see updated bus journeys.

Last updated at 10:37 AM
ProviderDepartsDurationArrivesTransfers
Tickets
greyhound12:00 PM Louisville, KY
7h35
7:35 PM Chicago, IL0 transfersDirect
greyhound6:35 PM Louisville, KY
6h35
1:10 AM Chicago, IL0 transfersDirect
meinfernbus_flixbus11:30 PM Louisville, KY
5h40
5:10 AM Chicago, IL0 transfersDirect

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets Louisville, KY to Chicago, IL by bus or flight

Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Wed
Nov 19
Thu
Nov 20
Fri
Nov 21
Sat
Nov 22
Sun
Nov 23
Mon
Nov 24
Tue
Nov 25

Journey information

Overview: Bus from Louisville, KY to Chicago, IL

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Buses from Louisville, KY to Chicago, IL run on average 8 times per day, taking around 6h 27m. Cheap bus tickets for this journey start at $42 (€34) if you book in advance.

There are 8 buses per day. The earliest bus runs at 01:50, the last at 22:30. The fastest bus covers the 267 miles (431 km) distance in 5h 40m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
267 miles (431 km)
Average bus duration
6h 27m
Cheapest ticket price
$42 (€34)
Buses per day
8
Direct buses
8
Fastest bus
5h 40m
First bus
01:50
Last bus
22:30
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Bus providers: Greyhound, FlixBus, Transit Authority of River City from Louisville, KY to Chicago, ILYou can travel by bus between Louisville, KY to Chicago, IL with Greyhound, FlixBus, Transit Authority of River City for as low as $42 (€34). When you search for schedules and tickets, Omio will show you the best journey

FlixBus

About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
5h 40m
Cheapest Price
$43 (€35)
FlixBus frequency
2 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.

Greyhound

About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
6h 5m
Cheapest Price
$41 (€33)
Greyhound frequency
6 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.

Transit Authority of River City

Luggage & cancellation policy
Average Duration
6h 40m
Cheapest Price
$160 (€130)
Transit Authority of River City frequency
1 a day

FAQs: Bus from Louisville, KY to Chicago, IL

Find answers to the most common questions about traveling from Louisville, KY to Chicago, IL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Chicago, IL, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Louisville, KY to Chicago, IL can start from as little as $42 (€34) when you book in advance. The average bus ticket price for Louisville, KY to Chicago, IL is $61 (€49); however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Louisville, KY to Chicago, IL is 6 h 5 min   to travel the 267 mile (430 km) long trip, with around there are 10 buses per day. Journey times can vary on weekends and holidays.
The first bus from Louisville, KY to Chicago, IL leaves at 2: 40AM. Plan your trip with the Journey Planner   from Omio.
The last bus from Louisville, KY to Chicago, IL leaves at 10: 35PM.
There are 10 buses a day from Louisville, KY to Chicago, IL which require at least one change with Greyhound, FlixBus or Transit Authority of River City. Schedules can vary on holidays or weekends with fewer buses.
For the best Louisville, KY to Chicago, IL bus to book, you can travel safely and comfortably with Greyhound, FlixBus or Transit Authority of River City. However, it's always good to check all possible bus providers with services from Louisville, KY to Chicago, IL to compare what amenities they may offer.
The cheapest month to travel from Louisville, KY to Chicago, IL by bus is September.
You have options as you can travel to Chicago, IL from Louisville, KY 2 different ways: bus or flight.
Yes, the following accessibility options are available when taking the bus from Louisville, KY to Chicago, IL:
  • Greyhound
    • Assistance
    • Priority seating
    • Wheelchair-accessible buses.
  • FlixBus
    • Assistance
    • Priority boarding
    • Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Louisville, KY to Chicago, IL for bus providers Greyhound and FlixBus.
Some of the most interesting sights to explore in Chicago, IL are:
  • Millennium Park, a public park known for its modern art installations and the iconic Cloud Gate sculpture
  • Art Institute of Chicago, a renowned museum housing an extensive collection of art from around the world
  • Navy Pier, a popular entertainment destination featuring rides, restaurants, and lakefront views
  • Willis Tower Skydeck, an observation deck offering panoramic views of the city from one of the tallest buildings in the Western Hemisphere
  • Field Museum, a natural history museum with vast exhibits including the famous T. Rex skeleton, Sue.
The best things to do in Chicago, IL include:
  • Museum of Science and Industry, an interactive museum featuring exhibits on science, technology, and industry
  • Explore the vibrant neighborhoods of Chicago, such as Wicker Park and Lincoln Park, known for their unique shops and eateries
  • Take a river cruise to see the city's iconic architecture from a different perspective
  • Attend a live performance at the historic Chicago Theatre
  • Enjoy a day at Lincoln Park Zoo, one of the oldest zoos in the U. S. Offering free admission.
Yes, bikes are allowed on board the bus with bus providers Greyhound and FlixBus.
Whether you can cancel your bus ticket from Louisville, KY to Chicago, IL depends on the bus providers:
  • Greyhound
    • You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
  • FlixBus
    • You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.

To find the cheapest bus tickets for your trip from Louisville, KY to Chicago, IL, follow these tips:

  • Book in advance: Tickets are often cheaper when booked early.
  • Be flexible with dates and times: Traveling during off-peak hours or on weekdays can help you save money.
  • Use our search filters: Sort results by price to quickly identify the most affordable options.
  • Look for special deals or discounts: Check for promotions or discounts available on our website and app.
  • Start your search now and compare ticket prices to find the best deal!

    Yes, there is food available to purchase on board the bus from Louisville, KY to Chicago, IL.
    Yes, the following luggage options are included when booking a bus ticket from Louisville, KY to Chicago, IL:
    • Greyhound
      • One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
    • FlixBus
      • One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
    Yes, the following additional luggage options are available when booking a bus ticket from Louisville, KY to Chicago, IL:
    • Greyhound
      • $15 per additional bag.
    • FlixBus
      • Additional luggage can be purchased for a fee.
    Yes, you can bring your pet on the bus from Louisville, KY to Chicago, IL. The following conditions apply:
    • FlixBus
      • Small pets in carriers allowed
      • Guide dogs travel for free.
    You can reserve your seat on the bus from Louisville, KY to Chicago, IL with the following bus providers: Greyhound and FlixBus
    Yes, there are USB plugs on board the bus from Louisville, KY to Chicago, IL with the following bus providers: Greyhound and FlixBus.
    Yes, there is Wifi on board the bus from Louisville, KY to Chicago, IL with the following bus providers: Greyhound and FlixBus.

    popular bus stations

    Popular bus stations from Louisville, KY to Chicago, IL

    Louisville
    Chicago
    The major bus station for departures in Louisville is Louisville, W Muhammad Ali Blvd (Greyhound Bus Stop). Find all the information you need to know about services, amenities and connections at Louisville, W Muhammad Ali Blvd (Greyhound Bus Stop) for your trip from Louisville to Chicago.
    Louisville, W Muhammad Ali Blvd (Greyhound Bus Stop)
    information
    Louisville, W Broadway (Greyhound Bus Station)
    information
    HomeBusesBuses in USABus tickets to Chicago, ILLouisville, KY to Chicago, IL bus

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