- Must visit
The Getty Center
Major hilltop art museum with European paintings, decorative arts, architecture, and city views; one of Los Angeles’s signature cultural sites.
Cheapest price
$28
Average price
$28
Fastest journey
3 h 20 m
Average duration
3 h 20 m
Buses per day
1
Distance
182 km
The best way to find a cheap bus ticket from La Mesa, CA to Los Angeles, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from La Mesa, CA to Los Angeles, CA will cost around $28 if you buy it on the day, but the cheapest tickets can be found for only $28.
Of the 1 buses that leave La Mesa, CA for Los Angeles, CA on Mon, Jun 22, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Mon, Jun 22 the direct buses cover the 182 km distance in an average of 3 h 20 m but if you time it right, some buses will get you there in just 3 h 20 m .
On Mon, Jun 22 the slowest buses will take 3 h 20 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Omio recommends booking the train as it is the most popular option from La Mesa, CA to Los Angeles, CA among Omio's users. If you are prioritising price take the bus with prices starting from $24. For those with little time consider booking a train which can get you there in 2h 49m. The ticket price range depends on the travel mode: a bus costs an average of $24, and a flight costs an average of $186.
Distance: 113 miles (182 km)
| Bus | Most popular Train | Flight | Driving |
|---|---|---|---|
$33 Average price Cheapest | $39 Average price | $293 Average price | $33 Average price (fuel + tolls) |
4h 0m Average total duration 3h 30m Onboard + 30m Additional time* | 3h 19m Average total duration Fastest 2h 49m Onboard + 30m Additional time* | 12h 8m Average total duration 9h 8m Onboard + 3h 0m Additional time* | 2h 15m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from La Mesa, CA to Los Angeles, CA:
A bus is $6 (€5) less than a train for this route with tickets for a train from La Mesa, CA to Los Angeles, CA costing on average $39 (€32).
A bus is $260 (€213) less than a flight for this route with tickets for a flight from La Mesa, CA to Los Angeles, CA costing on average $293 (€240).
Other travel options to Los Angeles, CA take longer:
Bus takes on average 3h 30m.
Flight takes on average 9h 8m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 12:20AM | Arrival Time 05:20AM | Duration 5h00 | Departure days Sun | Cheapest price $30 |
Operator Greyhound | Departure Time 02:35AM | Arrival Time 05:20AM | Duration 2h45 | Departure days Sat | Cheapest price $39 |
Operator Amtrak | Departure Time 01:30PM | Arrival Time 04:57PM | Duration 3h27 | Departure days Sun | Cheapest price $40 |
Operator Greyhound | Departure Time 02:45PM | Arrival Time 06:40PM | Duration 3h55 | Departure days Fri | Cheapest price $32 |
Operator FlixBus | Departure Time 08:35PM | Arrival Time 11:55PM | Duration 3h20 | Departure days Tue, Wed, Thu | Cheapest price $26 |
Operator FlixBus | Departure Time 09:35PM | Arrival Time 12:55AM | Duration 3h20 | Departure days Mon, Tue, Wed, Thu | Cheapest price $24 |
The table below shows live departures for La Mesa, CA to Los Angeles, CA buses for today, Sunday, June 21. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 1:30 PM La Mesa, CA | 3h27 | 4:57 PM Los Angeles, CA | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus, flight, and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from La Mesa, CA to Los Angeles, CA run on average 34 times per day, taking around 3h 30m. Cheap bus tickets for this journey start at $24 (€19) if you book in advance.
There are 32 buses per day. The earliest bus runs at 00:05, the last at 23:30. The fastest bus covers the 113 miles (182 km) distance in 2h 45m.
Distance 113 miles (182 km) |
Average bus duration 3h 30m |
Cheapest ticket price $24 (€19) |
Buses per day 34 |
Direct buses 32 |
Fastest bus 2h 45m |
First bus 12:05 AM |
Last bus 11:30 PM |
Cheapest Month Nov |
Cheapest Day Tue |
High Season Jan - Mar |
Low Season Jul - Sep |
Busiest Day Mon |
Least Busy Day Mon |
Discover the best of Los Angeles — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Los Angeles trip today.
Major hilltop art museum with European paintings, decorative arts, architecture, and city views; one of Los Angeles’s signature cultural sites.
The largest art museum in the western United States, known for broad global collections and the iconic Urban Light installation.
Popular contemporary art museum in Downtown Los Angeles with works by Kusama, Warhol, and other major postwar artists.
Vast urban park with trails, scenic overlooks, and access to major attractions; a classic Los Angeles outdoor destination.
Iconic oceanfront boardwalk area with classic California views and broad appeal for first-time visitors.
Famous beachfront promenade known for street culture, skate scenes, murals, and constant people-watching.
A Los Angeles classic of thinly sliced roast beef on a roll, served with rich jus for dipping. It is one of the city’s most iconic old-school sandwiches.
Street tacos are central to Los Angeles food culture, especially carne asada, al pastor, and grilled fish tacos served on corn tortillas with salsa, onion, and cilantro.
A signature Los Angeles meal shaped by Koreatown, featuring grilled marinated meats, banchan, and shared dining. The city is especially known for its strong Korean barbecue scene.
Acclaimed fine dining restaurant known for refined seafood tasting menus and elegant service. One of Los Angeles’s top special-occasion destinations.
Historic downtown institution famous for the French dip sandwich. Casual, old-school atmosphere and one of Los Angeles’s most iconic food stops.
Well-known Oaxacan restaurant celebrated for complex moles, tlayudas, and mezcal. Lively atmosphere and a landmark for regional Mexican cuisine in Los Angeles.
Los Angeles is expensive for visitors. Hotels, parking, and dining add up quickly, though casual food and some neighborhoods offer better value.
Tip 18-20% at restaurants; 20%+ for great service. Bars: USD 1-2 per drink. Taxis/rideshares: 10-15%. Hotel staff: USD 2-5. Not expected at fast-food spots.
Find answers to the most common questions about traveling from La Mesa, CA to Los Angeles, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Los Angeles, CA, this guide helps you travel smarter and with confidence.

Most La Mesa, CA to Los Angeles, CA buses use the San Diego to Hantington Park station pair, with some services arriving at Los Angeles, Patsaouras Transit Plaza (Union Station). Use this guide to compare La Mesa, CA and Los Angeles, CA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Here are some other resources that might have the information you need