La Mesa, CA to Los Angeles, CA bus

Mon, Jun 22
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Alsa
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Rede Expressos
Costa Verde
2,000+ travel companies
FlixBus
Alsa
BlaBlaCar Bus
Rede Expressos
Costa Verde
2,000+ travel companies
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The cheapest and fastest buses from La Mesa, CA to Los Angeles, CA

Showing times and prices for Jun 22

Cheapest price

$28

Average price

$28

Fastest journey

3 h 20 m

Average duration

3 h 20 m

Buses per day

1

Distance

182 km

Cheap tickets

The best way to find a cheap bus ticket from La Mesa, CA to Los Angeles, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from La Mesa, CA to Los Angeles, CA will cost around $28 if you buy it on the day, but the cheapest tickets can be found for only $28.

Fast buses

Of the 1 buses that leave La Mesa, CA for Los Angeles, CA on Mon, Jun 22, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.

On Mon, Jun 22 the direct buses cover the 182 km distance in an average of 3 h 20 m but if you time it right, some buses will get you there in just 3 h 20 m .

On Mon, Jun 22 the slowest buses will take 3 h 20 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

  • FlixBus
    9:35 PM3h20
    La Mesa, CA
    12:55 AMLos Angeles, CA
    $281One-way
    0 transfers

Travel Information

Compare bus, flight, and train for La Mesa, CA to Los Angeles, CA

Omio recommends booking the train as it is the most popular option from La Mesa, CA to Los Angeles, CA among Omio's users. If you are prioritising price take the bus with prices starting from $24. For those with little time consider booking a train which can get you there in 2h 49m. The ticket price range depends on the travel mode: a bus costs an average of $24, and a flight costs an average of $186.

Distance: 113 miles (182 km)

Compare bus with

Bus
Most popular
Train
Flight
Driving

$33

Average price

Cheapest

$39

Average price

$293

Average price

$33

Average price

(fuel + tolls)

4h 0m

Average total duration

3h 30m

Onboard

+

30m

Additional time*

3h 19m

Average total duration

Fastest

2h 49m

Onboard

+

30m

Additional time*

12h 8m

Average total duration

9h 8m

Onboard

+

3h 0m

Additional time*

2h 15m

Average total duration

(door-to-door)

Direct Options

Direct Options

Direct Options

Direct Options

The cheapest way to travel from La Mesa, CA to Los Angeles, CA is a bus with an average price of $33 (€27).

This is compared to other travel options from La Mesa, CA to Los Angeles, CA:

A bus is $6 (€5) less than a train for this route with tickets for a train from La Mesa, CA to Los Angeles, CA costing on average $39 (€32).

A bus is $260 (€213) less than a flight for this route with tickets for a flight from La Mesa, CA to Los Angeles, CA costing on average $293 (€240).

The fastest way to travel from La Mesa, CA to Los Angeles, CA is by train with an average journey time of 2h 49m.

Other travel options to Los Angeles, CA take longer:

Bus takes on average 3h 30m.

Flight takes on average 9h 8m.

It's helpful to compare your options as there are 3 ways to travel between La Mesa, CA and Los Angeles, CA including taking a bus, flight, and train.
We recommend using the train as it is the most popular way to get from La Mesa, CA to Los Angeles, CA among Omio's users.
Take the bus. On this route, it's both cheaper and quicker than driving.

You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.

Direct coaches are operated by {directProviders}.

Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.

La Mesa, CA to Los Angeles, CA Bus Timetables

OperatorDeparture TimeArrival TimeDurationDeparture daysCheapest price
Operator
Greyhound
Departure Time
12:20AM
Arrival Time
05:20AM
Duration
5h00
Departure days
Sun
Cheapest price
$30
Operator
Greyhound
Departure Time
02:35AM
Arrival Time
05:20AM
Duration
2h45
Departure days
Sat
Cheapest price
$39
Operator
Amtrak
Departure Time
01:30PM
Arrival Time
04:57PM
Duration
3h27
Departure days
Sun
Cheapest price
$40
Operator
Greyhound
Departure Time
02:45PM
Arrival Time
06:40PM
Duration
3h55
Departure days
Fri
Cheapest price
$32
Operator
FlixBus
Departure Time
08:35PM
Arrival Time
11:55PM
Duration
3h20
Departure days
Tue, Wed, Thu
Cheapest price
$26
Operator
FlixBus
Departure Time
09:35PM
Arrival Time
12:55AM
Duration
3h20
Departure days
Mon, Tue, Wed, Thu
Cheapest price
$24

Live departures

La Mesa, CA to Los Angeles, CA bus times

The table below shows live departures for La Mesa, CA to Los Angeles, CA buses for today, Sunday, June 21. You can also manually refresh the results below to see updated bus journeys.

Last updated at
ProviderDepartsDurationArrivesTransfers
Tickets
Amtrak1:30 PM La Mesa, CA
3h27
4:57 PM Los Angeles, CA0 transfersDirect

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets La Mesa, CA to Los Angeles, CA by bus, flight, or train

Compare bus, flight, and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Mon
Jun 22
Tue
Jun 23
Wed
Jun 24
Thu
Jun 25
Fri
Jun 26
Sat
Jun 27
Sun
Jun 28

Journey information

Overview: Bus from La Mesa, CA to Los Angeles, CA

USAUSA
USAUSA
Icon of bus

Buses from La Mesa, CA to Los Angeles, CA run on average 34 times per day, taking around 3h 30m. Cheap bus tickets for this journey start at $24 (€19) if you book in advance.

There are 32 buses per day. The earliest bus runs at 00:05, the last at 23:30. The fastest bus covers the 113 miles (182 km) distance in 2h 45m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
113 miles (182 km)
Average bus duration
3h 30m
Cheapest ticket price
$24 (€19)
Buses per day
34
Direct buses
32
Fastest bus
2h 45m
First bus
12:05 AM
Last bus
11:30 PM
Cheapest Month
Nov
Cheapest Day
Tue
High Season
Jan - Mar
Low Season
Jul - Sep
Busiest Day
Mon
Least Busy Day
Mon
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Complete guide to Los Angeles

Things to do in Los Angeles

Discover the best of Los Angeles — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Los Angeles trip today.

  • Must visit

The Getty Center

Major hilltop art museum with European paintings, decorative arts, architecture, and city views; one of Los Angeles’s signature cultural sites.

  • Must visit

Los Angeles County Museum of Art (LACMA)

The largest art museum in the western United States, known for broad global collections and the iconic Urban Light installation.

  • Must visit

The Broad

Popular contemporary art museum in Downtown Los Angeles with works by Kusama, Warhol, and other major postwar artists.

United States Dollar

Los Angeles is expensive for visitors. Hotels, parking, and dining add up quickly, though casual food and some neighborhoods offer better value.

Average meal costs

Budget
USD 10-18 for fast food or casual takeout.
Mid-range
USD 25-45 per person at a mid-range restaurant.
Fine dining
USD 80+ per person before drinks and tip.
Coffee
USD 4-7 for a regular coffee or latte.

Tipping culture

Tip 18-20% at restaurants; 20%+ for great service. Bars: USD 1-2 per drink. Taxis/rideshares: 10-15%. Hotel staff: USD 2-5. Not expected at fast-food spots.

FAQs: Bus from La Mesa, CA to Los Angeles, CA

Find answers to the most common questions about traveling from La Mesa, CA to Los Angeles, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Los Angeles, CA, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from La Mesa, CA to Los Angeles, CA can start from as little as $24 (€19) when you book in advance. The average bus ticket price for La Mesa, CA to Los Angeles, CA is $33 (€27) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from La Mesa, CA to Los Angeles, CA is 2h 45m to travel the 113 miles (182 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from La Mesa, CA to Los Angeles, CA leaves at 12:05 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from La Mesa, CA to Los Angeles, CA leaves at 11:30 PM.
A trip to Los Angeles, CA from La Mesa, CA is worth doing but not as a day trip with a journey time of 2h 45m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from La Mesa, CA to Los Angeles, CA is November.
It's helpful to compare your options as there are 3 ways to travel between La Mesa, CA and Los Angeles, CA including taking a bus, flight, and train.
No, the bus from La Mesa, CA to Los Angeles, CA has no accessibility options.
No, there are no bathrooms on board the bus from La Mesa, CA to Los Angeles, CA.
Some of the most interesting sights to explore in Los Angeles, CA are:
  • Griffith Observatory, an iconic facility offering stunning views of Los Angeles and exhibits on astronomy
  • The Getty Center, a renowned art museum with impressive architecture and beautiful gardens
  • Santa Monica Pier, a historic landmark featuring an amusement park, aquarium, and scenic ocean views
  • Hollywood Walk of Fame, a famous sidewalk celebrating entertainment industry icons with star plaques
  • Los Angeles County Museum of Art (LACMA), the largest art museum in the western United States with diverse collections.
The best things to do in Los Angeles, CA include:
  • Explore the vibrant Venice Beach Boardwalk, known for its eclectic shops, street performers, and skate park
  • Visit the historic El Capitan Theatre for a classic movie experience
  • Take a scenic hike in Runyon Canyon Park, offering panoramic views of the city
  • Enjoy a live performance at the Walt Disney Concert Hall, known for its stunning architecture and acoustics
  • Discover the unique exhibits at the Natural History Museum of Los Angeles County.
No, bikes are not allowed on board the bus from La Mesa, CA to Los Angeles, CA.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
No, there is no food available to purchase on board the bus from La Mesa, CA to Los Angeles, CA.
No, luggage for the bus from La Mesa, CA to Los Angeles, CA needs to be booked in addition.
No, there are no additional luggage options for the bus from La Mesa, CA to Los Angeles, CA.
Unfortunately, pets are not allowed on the bus from La Mesa, CA to Los Angeles, CA.
No, there are no USB plugs on board the bus from La Mesa, CA to Los Angeles, CA.
No, there is no WiFi on board the bus from La Mesa, CA to Los Angeles, CA.
Since neither La Mesa, CA nor Los Angeles, CA are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the train as it is the most popular way to get from La Mesa, CA to Los Angeles, CA among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Los Angeles, travelers should be cautious of pickpocketing and vehicle break-ins, especially in crowded or tourist-heavy areas like Hollywood and Venice Beach. Common scams include fake ticket vendors near popular attractions and overcharging by unlicensed ride services. It's important to use official transportation options, stay aware of surroundings, and avoid sharing personal information with strangers to stay safe.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

popular bus stations

Popular bus stations from La Mesa, CA to Los Angeles, CA

Most La Mesa, CA to Los Angeles, CA buses use the San Diego to Hantington Park station pair, with some services arriving at Los Angeles, Patsaouras Transit Plaza (Union Station). Use this guide to compare La Mesa, CA and Los Angeles, CA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.

Departure bus stations in La Mesa
Arrival bus stations in Los Angeles
Los Angeles, Patsaouras Transit Plaza (Union Station)
City-centre transport

Getting to Los Angeles, Patsaouras Transit Plaza (Union Station) from Los Angeles city centre

Bus4X · 8m · $2
SubwayMetro B Line, Metro D Line · 12m · $2 · every ~24 min
Los Angeles, Cesar E Chavez / Vignes
City-centre transport

Getting to Los Angeles, Cesar E Chavez / Vignes from Los Angeles city centre

Bus40, 74 · 3m · $2 · every ~15 min
33 · 4m · $2 · every ~9 min
D · 11m · $5 · every ~12 min
490, 495, 499, 699, 493, 498, 707 · 13m · $7 · every ~9 min
TramMetro A Line · 10m · $2 · every ~12 min
SubwayMetro B Line, Metro D Line · 10m · $2 · every ~24 min
Los Angles, S Hope St. USC Parking
City-centre transport

Getting to Los Angles, S Hope St. USC Parking from Los Angeles city centre

Bus92 · 1m · $2 · every ~6 min
D · 2m · $5 · every ~12 min

More options for your journey from La Mesa, CA to Los Angeles, CA

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