- Must visit
San Francisco Museum of Modern Art
Major modern and contemporary art museum with an internationally important collection and frequent blockbuster exhibitions.
Cheapest price
$151
Average price
$159
Fastest journey
11 h 15 m
Average duration
13 h 50 m
Buses per day
2
Distance
720 km
The best way to find a cheap bus ticket from La Jolla, CA to San Francisco, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from La Jolla, CA to San Francisco, CA will cost around $159 if you buy it on the day, but the cheapest tickets can be found for only $151.
Of the 2 buses that leave La Jolla, CA for San Francisco, CA on Sun, Jul 12, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sun, Jul 12 the direct buses cover the 720 km distance in an average of 13 h 50 m but if you time it right, some buses will get you there in just 11 h 15 m .
On Sun, Jul 12 the slowest buses will take 16 h 25 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
· 

· Omio recommends booking the bus as it is the most popular option from La Jolla, CA to San Francisco, CA among Omio's users. If you are prioritising price take the train with prices starting from $82. For those with little time consider booking a flight which can get you there in 6h 6m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.6kg. The ticket price range depends on the travel mode: a train costs an average of $82, and a flight costs an average of $251.
Distance: 447 miles (720 km)
Most popular Bus | Flight | Train |
|---|---|---|
$197 Average price | $251 Average price | $82 Average price Cheapest |
10h 45m Average total duration 10h 15m Onboard + 30m Additional time* | 9h 6m Average total duration Fastest 6h 6m Onboard + 3h 0m Additional time* | 14h 20m Average total duration 13h 50m Onboard + 30m Additional time* |
0.7 - 1.8kg CO2 emissions | 2.2 - 4.3kg CO2 emissions | 0.2 - 0.6kg CO2 emissions Lowest |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from La Jolla, CA to San Francisco, CA:
A train is $115 (€95) less than a bus for this route with tickets for a bus from La Jolla, CA to San Francisco, CA costing on average $197 (€162).
A train is $169 (€139) less than a flight for this route with tickets for a flight from La Jolla, CA to San Francisco, CA costing on average $251 (€207).
Other travel options to San Francisco, CA take longer:
Bus takes on average 10h 15m.
Train takes on average 13h 50m.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 05:40AM | Arrival Time 10:05PM | Duration 16h25 | Departure days Sun | Cheapest price $151 |
Operator San Diego Metro Transit | Departure Time 06:51PM | Arrival Time 07:15AM | Duration 12h24 | Departure days Mon, Tue, Wed, Thu | Cheapest price $151 |
Operator Greyhound | Departure Time 07:55PM | Arrival Time 07:10AM | Duration 11h15 | Departure days Sun | Cheapest price $167 |
Operator Greyhound | Departure Time 11:15PM | Arrival Time 02:15PM | Duration 15h00 | Departure days Sat | Cheapest price $197 |
The table below shows live departures for La Jolla, CA to San Francisco, CA buses for today, Saturday, July 11. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 11:15 PM La Jolla, CA | 15h00 | 2:15 PM San Francisco, CA | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from La Jolla, CA to San Francisco, CA run on average 13 times per day, taking around 10h 15m. Cheap bus tickets for this journey start at $197 (€162) but you can travel from only $82 (€68) by train.
The earliest bus runs at 04:10, the last at 23:25. The fastest bus covers the 447 miles (720 km) distance in 15h 0m.
Distance 447 miles (720 km) |
Average bus duration 10h 15m |
Cheapest ticket price $197 (€162) |
Buses per day 13 |
Fastest bus 15h 0m |
First bus 4:10 AM |
Last bus 11:25 PM |
Cheapest Month May |
Cheapest Day Thu |
High Season Oct - Dec |
Low Season Jan - Mar |
Discover the best of San Francisco — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect San Francisco trip today.
Major modern and contemporary art museum with an internationally important collection and frequent blockbuster exhibitions.
Hands-on science and art museum on the Embarcadero, especially popular for interactive exhibits and bay views.
Leading fine arts museum in Golden Gate Park, known for American art, textiles, and its observation tower.
Busy waterfront district known for classic San Francisco atmosphere, bay views, piers, and easy access to major sights.
Famous crooked block with steep curves, manicured gardens, and one of the city's most photographed street scenes.
Huge urban park with gardens, lakes, museums, and broad walking and cycling routes across the western city.
A tomato-based seafood stew created by Italian American fishermen in San Francisco, typically filled with crab, clams, mussels, shrimp, and fish.
San Francisco’s famous tangy sourdough loaf, shaped by the city’s historic wild yeast culture and long baking tradition.
A large foil-wrapped burrito associated with the Mission District, usually packed with rice, beans, meat, salsa, and extras.
Classic San Francisco institution serving carved prime rib with old-fashioned hospitality and a lively, upscale supper-club feel.
Iconic Mission District taqueria celebrated for Mission-style burritos and tacos with a simple, always-busy casual atmosphere.
Historic seafood counter famous for ultra-fresh oysters, crab, and cioppino ingredients in a classic old-school San Francisco setting.
Prices are high for hotels, dining, parking, and taxes. Budget options exist, but overall costs rank among the highest in the US.
Tip 18-20% in restaurants; 20%+ for great service. Bars: USD 1-2 per drink. Taxis/rideshares: 10-15% or round up. Hotels: USD 2-5 for porters, USD 3-5 daily for housekeeping.
Find answers to the most common questions about traveling from La Jolla, CA to San Francisco, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at San Francisco, CA, this guide helps you travel smarter and with confidence.

Most La Jolla, CA to San Francisco, CA buses use the La Jolla, UCSD Health La Jolla Station to San Francisco, Transit Center Bay 29 station pair, with some services arriving at San Francisco, Townsend Street / 5th Street. Use this guide to compare La Jolla, CA and San Francisco, CA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Here are some other resources that might have the information you need