- Must visit
Brewery Museum
Modern interactive brewery museum in a 15th-century malt house, explaining beer-making history and daily life in old Plzeň.
Cheapest price
€22
Average price
€26
Fastest journey
4 h 10 m
Average duration
4 h 43 m
Buses per day
3
Distance
65 km
The best way to find a cheap bus ticket from Karlovy Vary to Plzeň is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Karlovy Vary to Plzeň will cost around €26 if you buy it on the day, but the cheapest tickets can be found for only €22.
It's difficult to get from Karlovy Vary to Plzeň without transferring at least once.
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBusBuses from Karlovy Vary to Plzeň run on average 6 times per day, taking around 2h 23m. Cheap bus tickets for this journey start at €4 if you book in advance.
There are 3 buses per day. The earliest bus runs at 05:30, the last at 20:30. The fastest bus covers the 40 miles (65 km) distance in 1h 16m.
Distance 40 miles (65 km) |
Average bus duration 2h 23m |
Cheapest ticket price €4 |
Buses per day 6 |
Direct buses 3 |
Fastest bus 1h 16m |
First bus 5:30 AM |
Last bus 8:30 PM |
Cheapest Month Feb |
Cheapest Day Sun |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Sun |
Least Busy Day Fri |
Best time to book 1 day |
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 04:30AM | Arrival Time 11:15AM | Duration 6h45 | Departure days Mon | Cheapest price €8 |
Operator FlixBus | Departure Time 07:35AM | Arrival Time 12:15PM | Duration 4h40 | Departure days Tue, Wed, Thu, Fri, Sat, Sun | Cheapest price €22 |
Operator FlixBus | Departure Time 02:10PM | Arrival Time 07:40PM | Duration 5h30 | Departure days Mon | Cheapest price €12 |
Operator FlixBus | Departure Time 02:30PM | Arrival Time 07:35PM | Duration 5h05 | Departure days Mon, Tue, Thu, Fri | Cheapest price €12 |
Operator FlixBus | Departure Time 03:10PM | Arrival Time 08:40PM | Duration 5h30 | Departure days Mon | Cheapest price €14 |
Operator FlixBus | Departure Time 03:30PM | Arrival Time 07:35PM | Duration 4h05 | Departure days Sat, Sun | Cheapest price €31 |
Operator FlixBus | Departure Time 04:10PM | Arrival Time 09:40PM | Duration 5h30 | Departure days Fri | Cheapest price €28 |
Operator FlixBus | Departure Time 05:30PM | Arrival Time 09:40PM | Duration 4h10 | Departure days Mon, Tue, Wed, Thu, Sun | Cheapest price €8 |
Operator FlixBus | Departure Time 05:40PM | Arrival Time 09:40PM | Duration 4h00 | Departure days Sat | Cheapest price €22 |
Operator FlixBus | Departure Time 06:30PM | Arrival Time 11:50PM | Duration 5h20 | Departure days Tue, Wed, Thu, Fri, Sat, Sun | Cheapest price €23 |
Operator FlixBus | Departure Time 08:30PM | Arrival Time 01:15AM | Duration 4h45 | Departure days Fri, Sat, Sun | Cheapest price €22 |
The table below shows live departures for Karlovy Vary to Plzeň buses for today, Tuesday, August 4. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 2:30 PM Karlovy Vary, Dolní Nádraží | 5h05 | 7:35 PM Plzeň, Centrální Autobusové Nádraží | 1 transfer | |
FlixBus · FlixBus | 5:30 PM Karlovy Vary, Dolní Nádraží | 4h10 | 9:40 PM Plzeň, Centrální Autobusové Nádraží | 1 transfer | |
FlixBus · FlixBus | 6:30 PM Karlovy Vary, Dolní Nádraží | 5h20 | 11:50 PM Plzeň, Centrální Autobusové Nádraží | 1 transfer | |
| Wednesday, August 5 | |||||
FlixBus · FlixBus | 7:35 AM Karlovy Vary, Dolní Nádraží | 4h40 | 12:15 PM Plzeň, Centrální Autobusové Nádraží | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Discover the best of Plzeň — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Plzeň trip today.
Modern interactive brewery museum in a 15th-century malt house, explaining beer-making history and daily life in old Plzeň.
Major regional museum with archaeology, applied arts, weapons and civic history, housed in a remarkable historic building.
Popular puppetry museum in the old town presenting Czech marionette traditions, stagecraft and family-friendly exhibits.
Plzeň’s main square, lined with major monuments and colorful facades. The essential starting point for exploring the historic center.
Historic pedestrian street linking the station area with the center, valued for architecture, shops and an everyday city atmosphere.
Large urban park with mature trees, paths and open lawns. A favorite local place for walks close to the old town.
Bottom-fermented pale lager first brewed in Plzeň in 1842. Its soft water, Saaz hops, and triple decoction made the city world-famous.
Crisp fried cheese, usually Edam, served with tartar sauce and potatoes. A classic Czech pub meal commonly eaten in Plzeň.
Beef goulash slow-cooked with onions and paprika, often served with bread dumplings. A staple in Czech beer halls across Plzeň.
Refined fine dining with seasonal tasting menus, polished service, and a modern setting inside Hotel Rous.
Historic brewery restaurant beside Pilsner Urquell. Best for unfiltered tank beer and classic Czech dishes in a lively traditional setting.
Traditional Plzeň beer hall known for Pilsner Urquell, hearty Czech meals, and a classic local pub atmosphere.
Moderate for Czech city travel: hotels, dining, and transit are usually cheaper than Prague, but tourist areas and brewery venues can cost more.
Tip about 5-10% in restaurants if service is good, often by rounding up. Round up small taxi fares. In cafes, small change or rounding up is common.
Official public transport app
Plzeň, Centrální Autobusové Nádraží -> Náměstí Republiky, Plzeň
Find answers to the most common questions about traveling from Karlovy Vary to Plzeň by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Plzeň, this guide helps you travel smarter and with confidence.

Most Karlovy Vary to Plzeň buses use the Karlovy Vary, Dolní Nádraží to Plzeň, Centrální Autobusové Nádraží station pair, with some services arriving at Plzeň, Severka. Use this guide to compare Karlovy Vary and Plzeň bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Karlovy Vary, Dolní Nádraží has practical services for this route, including Wifi, Parking, Dining, ATM, Accessibility, WC, and Ticket Office.
Food options include: Cafeteria Dolní (in the station), Fast Food Express (in the station), Coffee Corner (in the station).
Free Wi-Fi. ATMs are located near the entrance.
Ticket office support is available at Karlovy Vary, Dolní Nádraží.
Available at Karlovy Vary, Dolní Nádraží: Parking, WC.
Accessibility facilities are available at Karlovy Vary, Dolní Nádraží: Elevators, ramps.
Here are some other resources that might have the information you need